LIVIVO - Search results -

Search results

Result 1 - 10 of total 2179

Search options

Article: Biomarkers for hepatic sinusoidal obstruction syndrome after hematopoietic cell transplantation.

Lee, Je-Hwan

2015 Volume 50, Issue 3, Page(s) 123–125

Language	English
Publishing date	2015-09-22
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2711910-5
ISSN	2288-0011 ; 2287-979X
ISSN (online)	2288-0011
ISSN	2287-979X
DOI	10.5045/br.2015.50.3.123
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Natural Killer Cell Activity Test Helps to Suspect Aggressive Natural Killer Cell Leukemia - Diagnostic Challenge.

You, Eunkyoung / Park, Chan-Jeoung / Lee, Min Young / Cho, Young-Uk / Jang, Seongsoo / Lee, Jung-Hee / Lee, Je-Hwan / Lee, Kyoo-Hyung

International journal of medical sciences

2023 Volume 20, Issue 2, Page(s) 206–210

Abstract: Aggressive natural killer cell leukemia (ANKL) is a rare disease with an aggressive clinical course. We aimed to assess the clinicopathological characteristics of the difficult to diagnose ANKL. During ten years, nine patients with ANKL were diagnosed. ... ...

Abstract	Aggressive natural killer cell leukemia (ANKL) is a rare disease with an aggressive clinical course. We aimed to assess the clinicopathological characteristics of the difficult to diagnose ANKL. During ten years, nine patients with ANKL were diagnosed. All the patients exhibited aggressive clinical course and underwent the BM study to rule out lymphoma and hemophagocytic lymphohistiocytosis (HLH). BM examination showed varying degrees of infiltration of neoplastic cells, which were mainly positive for CD2, CD56, cytoplasmic CD3 and EBV in situ hybridization. Five BM aspirates showed histiocytic proliferation with active heomphagocytosis. Normal or increased NK cell activity test results were obtained from 3 patients who were available for testing. Four had multiple BM studies until diagnosis. An aggressive clinical course and positive EBV in situ hybridization, often with associated secondary HLH, should raise the suspicion of an ANKL. Conducting additional supplementary tests such as NK cell activity and NK cell proportion would be helpful for the diagnosis of ANKL.
MeSH term(s)	Humans ; Leukemia, Large Granular Lymphocytic/diagnosis ; Leukemia, Large Granular Lymphocytic/pathology ; Lymphoma ; Killer Cells, Natural/pathology ; Disease Progression
Language	English
Publishing date	2023-01-16
Publishing country	Australia
Document type	Journal Article
ZDB-ID	2151424-0
ISSN	1449-1907 ; 1449-1907
ISSN (online)	1449-1907
ISSN	1449-1907
DOI	10.7150/ijms.77583
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Effect of changes in lymphocyte subsets at diagnosis in acute myeloid leukemia on prognosis: association with complete remission rates and relapse free survivals.

Park, Sang Hyuk / Bae, Mi-Hyun / Park, Chan-Jeoung / Cho, Young-Uk / Jang, Seongsoo / Lee, Je-Hwan / Lee, Kyoo-Hyung

Journal of hematopathology

2023 Volume 16, Issue 2, Page(s) 73–84

Abstract: We prospectively investigated whether the characteristics of lymphocyte subsets at diagnosis in acute myeloid leukemia (AML) patients are different from healthy controls and affect treatment outcomes. A total of 91 AML patients classified into 3 genetic ... ...

Abstract	We prospectively investigated whether the characteristics of lymphocyte subsets at diagnosis in acute myeloid leukemia (AML) patients are different from healthy controls and affect treatment outcomes. A total of 91 AML patients classified into 3 genetic risk subgroups (favorable/intermediate/poor) according to 2022 NCCN guidelines were enrolled. We measured lymphocyte subsets by flow cytometry with peripheral blood samples at diagnosis and compared results with healthy controls. Influences of lymphocyte subsets on complete remission (CR) rates and survivals were also evaluated. AML patients had significantly lower numbers and proportions of CD56
MeSH term(s)	Humans ; Lymphocyte Subsets ; Lymphocyte Count ; Leukemia, Myeloid, Acute/diagnosis ; Pathologic Complete Response ; Killer Cells, Natural ; Chronic Disease
Language	English
Publishing date	2023-03-07
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2438687-X
ISSN	1865-5785 ; 1868-9256
ISSN (online)	1865-5785
ISSN	1868-9256
DOI	10.1007/s12308-023-00536-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Real-World Treatment Patterns and Clinical Outcomes in Korean Patients With AML Ineligible for First-Line Intensive Chemotherapy: A Subanalysis of the CURRENT Study, a Non-Interventional, Retrospective Chart Review.

Bang, Soo-Mee / Kang, Ka-Won / Song, Ik-Chan / Llamas, Cynthia / Duan, Yinghui / Jeong, Ji-Young / Lee, Je-Hwan

Journal of Korean medical science

2023 Volume 38, Issue 44, Page(s) e345

Abstract: Background: Although most elderly patients with acute myeloid leukemia (AML) are ineligible for intensive chemotherapy (ICT), treatment options remain limited. CURRENT (UMIN000037786), a real-world, non-interventional, retrospective chart review, ... ...

Abstract	Background: Although most elderly patients with acute myeloid leukemia (AML) are ineligible for intensive chemotherapy (ICT), treatment options remain limited. CURRENT (UMIN000037786), a real-world, non-interventional, retrospective chart review, evaluated clinical outcomes, clinicopathologic characteristics, and treatment patterns in these patients. We present results from a subanalysis of Korean patients in this study. Methods: Patients were aged ≥ 18 years with primary or secondary AML ineligible for ICT who initiated first-line systemic therapy or best supportive care (BSC) between 2015 and 2018 across four centers in Korea. Primary endpoint was overall survival (OS) from diagnosis. Secondary endpoints included progression-free survival (PFS), time to treatment failure, and response rates. Data analyses were primarily descriptive, with time-to-event outcomes estimated using the Kaplan-Meier method, and Cox regression used to determine prognostic factors for survival. Results: Among 194 patients enrolled, 84.0% received systemic therapy and 16.0% received BSC. Median age at diagnosis was 74 and 78 years, and Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1 was reported in 73.0% and 48.4% of patients, respectively; poor cytogenetic risk was reported in 30.1% and 16.1% of patients. Median OS was 7.83 vs. 4.50 months, and median PFS was 6.73 vs. 4.50 months in the systemic therapy vs. BSC groups. Prognostic factors affecting OS included secondary AML (hazard ratio, 1.67 [95% confidence interval, 1.13-2.45]), ECOG performance status ≥ 2 (2.41 [1.51-3.83]), poor cytogenetic risk (2.10 [1.36-3.24]), and Charlson comorbidity index ≥ 1 (2.26 [1.43-3.58]). Conclusion: Clinical outcomes are poor in Korean patients with AML ineligible for ICT who are prescribed current systemic therapies or BSC. There is a substantial unmet need for novel agents (monotherapy or in combination) to improve clinical outcomes in this patient population.
MeSH term(s)	Aged ; Humans ; Retrospective Studies ; Leukemia, Myeloid, Acute/drug therapy ; Proportional Hazards Models ; Progression-Free Survival ; Republic of Korea ; Treatment Outcome ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/adverse effects
Language	English
Publishing date	2023-11-13
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	639262-3
ISSN	1598-6357 ; 1011-8934
ISSN (online)	1598-6357
ISSN	1011-8934
DOI	10.3346/jkms.2023.38.e345
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 3163: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Tongue-in-Groove: A Novel Implant Design for a Blow-Out Fracture.

Byeon, Je-Yeon / Hwang, Yong-Seon / Choi, Hwan-Jun / Lee, Da-Woon / Kim, Jun-Hyuk

Journal of clinical medicine

2024 Volume 13, Issue 6

Abstract: ... ...

Abstract	Background
Language	English
Publishing date	2024-03-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm13061766
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Interleukin-15 and -21-activated, donor-derived NK cell infusion after haploidentical HCT in high-risk AML and MDS-a cohort analysis.

Lee, Kyoo-Hyung / Lee, Sewon / Park, Young Hoon / Mun, Yeung-Chul / Choi, Eun-Ji / Choi, Yunsuk / Park, Han-Seung / Lee, Jung-Hee / Lee, Je-Hwan / Park, Soo-Yeon / Yoon, Suk Ran / Choi, Inpyo

Leukemia

2023 Volume 38, Issue 2, Page(s) 451–454

MeSH term(s)	Humans ; Interleukin-15/genetics ; Neoplasm Recurrence, Local ; Killer Cells, Natural ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/therapy ; Cohort Studies ; Hematopoietic Stem Cell Transplantation ; Graft vs Host Disease
Chemical Substances	Interleukin-15
Language	English
Publishing date	2023-12-22
Publishing country	England
Document type	Letter ; Research Support, Non-U.S. Gov't
ZDB-ID	807030-1
ISSN	1476-5551 ; 0887-6924
ISSN (online)	1476-5551
ISSN	0887-6924
DOI	10.1038/s41375-023-02121-6
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2295: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Blindsided: An Unusual Case of Ocular Ischemic Syndrome and Orthostatic Dizziness Caused by Brachiocephalic Trunk Stenosis.

Kim, Yoon Seob / Won, Je Hwan / Lee, Seong-Joon

Journal of clinical neurology (Seoul, Korea)

2023 Volume 19, Issue 3, Page(s) 324–326

Language	English
Publishing date	2023-05-07
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2500489-X
ISSN	2005-5013 ; 1738-6586
ISSN (online)	2005-5013
ISSN	1738-6586
DOI	10.3988/jcn.2022.0366
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Increased PD-1 expression of bone marrow T-cells in acute myeloid leukaemia patients after stem cell transplantation, and its association with overall survival.

You, Eunkyoung / Park, Chan-Jeoung / Cho, Young-Uk / Jang, Seongsoo / Lee, Min Young / Kim, Hery / Koh, Kyung Nam / Im, Ho Joon / Choi, Eun-Ji / Lee, Je-Hwan / Lee, Kyoo-Hyung

Annals of clinical biochemistry

2023 Volume 61, Issue 2, Page(s) 79–89

Abstract: Background: Immune checkpoints are involved in mechanisms by which tumours escape from the host immune system. Our aim was to evaluate acute myeloid leukaemia (AML) patients to determine expression levels of checkpoint molecules according to diagnosis ... ...

Abstract	Background: Immune checkpoints are involved in mechanisms by which tumours escape from the host immune system. Our aim was to evaluate acute myeloid leukaemia (AML) patients to determine expression levels of checkpoint molecules according to diagnosis and treatments, and to identify optimal candidates for checkpoint blockade. Methods: Bone marrow (BM) samples were obtained from 279 AML patients at different disease status and from 23 controls. Flow cytometric analyses of PD-1 and PD-L1/PD-L2 expression were performed. Results: Programmed death-1 (PD-1) expression levels on CD8 Conclusions: In conclusion, patients who underwent allo-SCT exhibited high PD-1 expression, suggesting that allo-SCT increases PD-1 expression on T-cells, and the patients with high PD-1 expression on CD8
MeSH term(s)	Humans ; Programmed Cell Death 1 Receptor/metabolism ; B7-H1 Antigen/metabolism ; CD8-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/pathology ; Bone Marrow/metabolism ; Bone Marrow/pathology ; Leukemia, Myeloid, Acute/therapy ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/pathology ; Stem Cell Transplantation
Chemical Substances	Programmed Cell Death 1 Receptor ; B7-H1 Antigen
Language	English
Publishing date	2023-11-21
Publishing country	England
Document type	Journal Article
ZDB-ID	390309-6
ISSN	1758-1001 ; 0004-5632
ISSN (online)	1758-1001
ISSN	0004-5632
DOI	10.1177/00045632231184716
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 889: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: A comparison of coagulation test results from heparinized central venous catheter and venipuncture.

Jeon, Mijin / Han, Arum / Kang, Hyeran / Lee, Kyoo-Hyung / Lee, Je-Hwan / Lee, Jung-Hee

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis

2020 Volume 31, Issue 2, Page(s) 145–151

Abstract: Blood sampling via heparin-locked central venous catheter, including coagulation tests, is possible in accordance with the Clinical & Laboratory Standards Institute guidelines. However, differences exist between the test values of samples obtained from ...

Abstract	: Blood sampling via heparin-locked central venous catheter, including coagulation tests, is possible in accordance with the Clinical & Laboratory Standards Institute guidelines. However, differences exist between the test values of samples obtained from central venous catheter and those obtained from peripheral veins, even the guidelines are followed. To compare the coagulation time between blood samples from the heparin-locked central venous catheter and peripheral veins. In total, 72 hospitalized patients using heparin-locked Hickman catheters were enrolled. Blood samples for coagulation testing were simultaneously obtained via the peripheral veins and heparin-locked Hickman catheters. For sampling from the catheters, 0.9% sodium chloride flushing was performed and 10 or 23 ml of blood was discarded prior to collecting the coagulation test samples. Correlation, Bland-Altman plot, covariate, and regression analysis were performed for data analyses. Despite following the guidelines, the activated partial thromboplastin time test values differed. In the 10 ml of blood discard group, a correlation coefficient of 0.378 and a mean bias of 6.46 s were determined, while and in the 23 ml blood discard group, a correlation coefficient of 0.80 and a mean bias of 2.518 s were determined. Therefore, the volume of blood discarded from the heparin-locked Hickman catheters may affect the activated partial thromboplastin time test values.
MeSH term(s)	Bias ; Blood Coagulation Tests/methods ; Blood Coagulation Tests/standards ; Blood Specimen Collection ; Central Venous Catheters ; Correlation of Data ; Heparin ; Humans ; Partial Thromboplastin Time ; Phlebotomy
Chemical Substances	Heparin (9005-49-6)
Language	English
Publishing date	2020-01-24
Publishing country	England
Document type	Comparative Study ; Journal Article
ZDB-ID	1033551-1
ISSN	1473-5733 ; 0957-5235
ISSN (online)	1473-5733
ISSN	0957-5235
DOI	10.1097/MBC.0000000000000890
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2920: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Book ; Online: Robust Imitation via Mirror Descent Inverse Reinforcement Learning

Han, Dong-Sig / Kim, Hyunseo / Lee, Hyundo / Ryu, Je-Hwan / Zhang, Byoung-Tak

2022

Abstract: Recently, adversarial imitation learning has shown a scalable reward acquisition method for inverse reinforcement learning (IRL) problems. However, estimated reward signals often become uncertain and fail to train a reliable statistical model since the ... ...

Abstract	Recently, adversarial imitation learning has shown a scalable reward acquisition method for inverse reinforcement learning (IRL) problems. However, estimated reward signals often become uncertain and fail to train a reliable statistical model since the existing methods tend to solve hard optimization problems directly. Inspired by a first-order optimization method called mirror descent, this paper proposes to predict a sequence of reward functions, which are iterative solutions for a constrained convex problem. IRL solutions derived by mirror descent are tolerant to the uncertainty incurred by target density estimation since the amount of reward learning is regulated with respect to local geometric constraints. We prove that the proposed mirror descent update rule ensures robust minimization of a Bregman divergence in terms of a rigorous regret bound of $\mathcal{O}(1/T)$ for step sizes $\{\eta_t\}_{t=1}^{T}$. Our IRL method was applied on top of an adversarial framework, and it outperformed existing adversarial methods in an extensive suite of benchmarks. Comment: NeurIPS 2022
Keywords	Computer Science - Machine Learning
Subject code	006
Publishing date	2022-10-20
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED