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  1. Article ; Online: Optimising zoledronate treatment holiday duration without loss of fracture prevention.

    Drake, Matthew T

    The lancet. Diabetes & endocrinology

    2024  Volume 12, Issue 4, Page(s) 217–219

    MeSH term(s) Humans ; Zoledronic Acid/therapeutic use ; Holidays ; Fractures, Bone/prevention & control ; Diphosphonates/therapeutic use ; Bone Density Conservation Agents/therapeutic use ; Bone Density
    Chemical Substances Zoledronic Acid (6XC1PAD3KF) ; Diphosphonates ; Bone Density Conservation Agents
    Language English
    Publishing date 2024-03-04
    Publishing country England
    Document type Journal Article
    ISSN 2213-8595
    ISSN (online) 2213-8595
    DOI 10.1016/S2213-8587(24)00064-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Editorial - Cancer and Bone special issue.

    Edwards, Claire M / Drake, Matthew T

    Bone

    2022  Volume 158, Page(s) 116369

    MeSH term(s) Bone and Bones ; Humans ; Neoplasms
    Language English
    Publishing date 2022-02-14
    Publishing country United States
    Document type Editorial
    ZDB-ID 632515-4
    ISSN 1873-2763 ; 8756-3282
    ISSN (online) 1873-2763
    ISSN 8756-3282
    DOI 10.1016/j.bone.2022.116369
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    Zs.A 1571: Show issues Location:
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    Zs.MO 332: Show issues

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  3. Article ; Online: Commentary on the endocrine society clinical practice guideline on the "treatment of hypercalcemia of malignancy in adults".

    El-Hajj Fuleihan, Ghada / Drake, Matthew T

    Metabolism: clinical and experimental

    2023  Volume 143, Page(s) 155553

    MeSH term(s) Adult ; Humans ; Hypercalcemia/therapy ; Hypercalcemia/drug therapy ; Neoplasms/complications ; Neoplasms/therapy ; Bone Density Conservation Agents/therapeutic use
    Chemical Substances Bone Density Conservation Agents
    Language English
    Publishing date 2023-04-05
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 80230-x
    ISSN 1532-8600 ; 0026-0495
    ISSN (online) 1532-8600
    ISSN 0026-0495
    DOI 10.1016/j.metabol.2023.155553
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    Uc I Zs.316: Show issues Location:
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  4. Article: Pros and Cons of Skeletal Medications in the COVID-19 Era.

    Tsourdi, Elena / Drake, Matthew T

    Current treatment options in rheumatology

    2022  Volume 8, Issue 3, Page(s) 56–69

    Abstract: Purpose of review: This review provides an overview regarding osteoporosis therapies during the COVID-19 pandemic.: Recent findings: The COVID-19 pandemic has disrupted treatments for osteoporosis and resulted in decreased adherence particularly for ... ...

    Abstract Purpose of review: This review provides an overview regarding osteoporosis therapies during the COVID-19 pandemic.
    Recent findings: The COVID-19 pandemic has disrupted treatments for osteoporosis and resulted in decreased adherence particularly for parenteral regimens. Osteoporosis medications are safe and effective during the pandemic and should be continued whenever possible. Bisphosphonates have long-lasting effects on bone turnover such that delays in their administration are unlikely to be harmful to skeletal health. In contrast, interruption of denosumab treatment is strongly discouraged because of rapid loss of bone mass and an associated increased risk for rebound vertebral fractures. When osteoanabolic treatments cannot be continued during the pandemic, change to an oral bisphosphonate is advised. Preclinical data suggest possible beneficial effects of some therapies against COVID-19, but require validation in clinical studies. Vitamin D deficiency is associated with a more severe COVID-19 clinical course but data supporting improvements in outcomes with vitamin D supplementation are lacking.
    Summary: The impact of the COVID-19 pandemic on long-term bone health remains unknown but focused interventions to ensure osteoporosis treatment initiation/maintenance should be implemented. Future studies are needed to determine whether osteoporosis medications have an impact on SARS-CoV-2 pathophysiology and COVID-19 clinical outcomes.
    Language English
    Publishing date 2022-07-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2198-6002
    ISSN 2198-6002
    DOI 10.1007/s40674-022-00192-7
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  5. Article ; Online: Hypothyroidism in Clinical Practice.

    Drake, Matthew T

    Mayo Clinic proceedings

    2018  Volume 93, Issue 9, Page(s) 1169–1172

    MeSH term(s) Humans ; Hypothyroidism ; Osteolysis ; Thyroxine
    Chemical Substances Thyroxine (Q51BO43MG4)
    Language English
    Publishing date 2018-09-07
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2018.07.015
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    Ua VI Zs.183: Show issues Location:
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  6. Article ; Online: Treatment of hypercalcaemia of malignancy in adults.

    Mc Donald, Darran / Drake, Matthew T / Crowley, Rachel K

    Clinical medicine (London, England)

    2023  Volume 23, Issue 5, Page(s) 503–507

    Abstract: Hypercalcaemia of malignancy (HCM) is a common metabolic complication of advanced malignancies with a prevalence varying from 2-30%, depending on cancer type and disease stage. HCM is associated with impaired quality of life, increased risk of ... ...

    Abstract Hypercalcaemia of malignancy (HCM) is a common metabolic complication of advanced malignancies with a prevalence varying from 2-30%, depending on cancer type and disease stage. HCM is associated with impaired quality of life, increased risk of hospitalisation and limited survival. Evidence-based guidelines for management of HCM have been lacking to date, despite its prevalence and detrimental impact. This concise guidance highlights key recommendations from the recent Endocrine Society Clinical Practice Guidelines on Treatment of Hypercalcaemia of Malignancy in Adults, published in December 2022. A systematic review and meta-analysis was commissioned to support the guideline development process. Key suggestions include the use of denosumab in preference to intravenous bisphosphonates as first-line treatment for HCM and the use of denosumab in cases of recurrent or refractory HCM in patients previously treated with intravenous bisphosphonates. The guideline also identifies priority areas for future research.
    MeSH term(s) Humans ; Adult ; Hypercalcemia/etiology ; Hypercalcemia/therapy ; Denosumab/therapeutic use ; Diphosphonates/therapeutic use ; Quality of Life ; Neoplasms/complications ; Bone Density Conservation Agents/therapeutic use
    Chemical Substances Denosumab (4EQZ6YO2HI) ; Diphosphonates ; Bone Density Conservation Agents
    Language English
    Publishing date 2023-09-29
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2048646-7
    ISSN 1473-4893 ; 1470-2118
    ISSN (online) 1473-4893
    ISSN 1470-2118
    DOI 10.7861/clinmed.2023-0227
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    Zs.A 5439: Show issues Location:
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  7. Article ; Online: Update on Approved Osteoporosis Therapies Including Combination and Sequential Use of Agents.

    Saul, Dominik / Drake, Matthew T

    Endocrinology and metabolism clinics of North America

    2021  Volume 50, Issue 2, Page(s) 179–191

    Abstract: Osteoporosis is characterized by reduced bone mass leading to diminished skeletal integrity and an increased risk for fracture. Multiple agents exist that are effective for the treatment of osteoporosis. These can be broadly categorized into those that ... ...

    Abstract Osteoporosis is characterized by reduced bone mass leading to diminished skeletal integrity and an increased risk for fracture. Multiple agents exist that are effective for the treatment of osteoporosis. These can be broadly categorized into those that reduce the risk for additional loss of bone mass (anti-resorptive agents) and those that augment existing bone mass (anabolic agents). This article reviews the different medications within each class, and discusses more recent data regarding the combination and sequential use of these medications for optimization of skeletal health in patients at high risk for fracture.
    MeSH term(s) Anabolic Agents/therapeutic use ; Bone Density ; Bone Density Conservation Agents/therapeutic use ; Fractures, Bone/etiology ; Fractures, Bone/prevention & control ; Humans ; Osteoporosis/complications ; Osteoporosis/drug therapy
    Chemical Substances Anabolic Agents ; Bone Density Conservation Agents
    Language English
    Publishing date 2021-05-21
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 92116-6
    ISSN 1558-4410 ; 0889-8529
    ISSN (online) 1558-4410
    ISSN 0889-8529
    DOI 10.1016/j.ecl.2021.03.010
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    Se 148: Show issues Location:
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  8. Article ; Online: Defining Very High Fracture Risk: Is FRAX Fit for Purpose?

    Compston, Juliet E / Drake, Matthew T

    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

    2020  Volume 35, Issue 8, Page(s) 1399–1403

    MeSH term(s) Humans ; Osteoporotic Fractures/epidemiology ; Risk Assessment
    Language English
    Publishing date 2020-07-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632783-7
    ISSN 1523-4681 ; 0884-0431
    ISSN (online) 1523-4681
    ISSN 0884-0431
    DOI 10.1002/jbmr.4134
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    Zs.A 2142: Show issues Location:
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  9. Article ; Online: Commentary.

    Drake, Matthew T

    Clinical chemistry

    2016  Volume 62, Issue 5, Page(s) 687–688

    MeSH term(s) Female ; Fractures, Bone ; Humans ; Sclerosis
    Language English
    Publishing date 2016-04-28
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 80102-1
    ISSN 1530-8561 ; 0009-9147
    ISSN (online) 1530-8561
    ISSN 0009-9147
    DOI 10.1373/clinchem.2015.248757
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    Ud II Zs.171: Show issues Location:
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  10. Article ; Online: Resistant Starch as a Dietary Intervention to Limit the Progression of Diabetic Kidney Disease.

    Drake, Anna M / Coughlan, Melinda T / Christophersen, Claus T / Snelson, Matthew

    Nutrients

    2022  Volume 14, Issue 21

    Abstract: Diabetes is the leading cause of kidney disease, and as the number of individuals with diabetes increases there is a concomitant increase in the prevalence of diabetic kidney disease (DKD). Diabetes contributes to the development of DKD through a number ... ...

    Abstract Diabetes is the leading cause of kidney disease, and as the number of individuals with diabetes increases there is a concomitant increase in the prevalence of diabetic kidney disease (DKD). Diabetes contributes to the development of DKD through a number of pathways, including inflammation, oxidative stress, and the gut-kidney axis, which may be amenable to dietary therapy. Resistant starch (RS) is a dietary fibre that alters the gut microbial consortium, leading to an increase in the microbial production of short chain fatty acids. Evidence from animal and human studies indicate that short chain fatty acids are able to attenuate inflammatory and oxidative stress pathways, which may mitigate the progression of DKD. In this review, we evaluate and summarise the evidence from both preclinical models of DKD and clinical trials that have utilised RS as a dietary therapy to limit the progression of DKD.
    MeSH term(s) Animals ; Humans ; Resistant Starch ; Starch/therapeutic use ; Starch/metabolism ; Diabetic Nephropathies/prevention & control ; Dietary Fiber/therapeutic use ; Dietary Fiber/metabolism ; Fatty Acids, Volatile/metabolism ; Diabetes Mellitus
    Chemical Substances Resistant Starch ; Starch (9005-25-8) ; Dietary Fiber ; Fatty Acids, Volatile
    Language English
    Publishing date 2022-10-28
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu14214547
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