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Article: Numerical analysis of a highly sensitive SOI MRR refractive index sensor with performance enhancement using graphene and gold.

Intisar, Tasin / Alam, Ahmed Shadman / Hoque, Ishtiaqul / Faruque, Md Omar

2024 Volume 10, Issue 4, Page(s) e26186

Abstract: This study proposes a simulation-based design for a Silicon-On-Insulator (SOI) ring resonator with a Figure of Merit (FOM) of 56.15 and a high sensitivity of up to 730 nm/RIU. The Finite-Difference Time-Domain (FDTD) technique was used to assess and ... ...

Abstract	This study proposes a simulation-based design for a Silicon-On-Insulator (SOI) ring resonator with a Figure of Merit (FOM) of 56.15 and a high sensitivity of up to 730 nm/RIU. The Finite-Difference Time-Domain (FDTD) technique was used to assess and evaluate the design quantitatively. Our design demonstrates higher sensitivity compared to many recent studies conducted on SOI-based sensors. The device structure follows a conventional ring resonator arrangement with a single waveguide, incorporating a 2D graphene layer on top of the SiO2 wafer and a gold nano-disc positioned at the center of the ring. Our findings highlight the device's susceptibility to refractive index variations, making it a desirable choice for various sensing applications. We have investigated the sensor's capabilities for sensing different concentrations of milkmilk. Graphene and gold materials enhance the device's response to light and provide comparatively higher sensitivity. The suggested design can serve as a blueprint for device fabrication, considering the practicality of implementing an SOI-based device using standard techniques for silicon processing.
Language	English
Publishing date	2024-02-14
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2024.e26186
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Evaluation of Efficacy and Safety of Combined Therapy of Melasma by using Azelic, Glycolic and Kojic Acid (Unitone and Neotone)

Intisar Ahmed Hasan, / Khudhair Kh Ibrahim Al-Kayally

Diyala Journal of Medicine, Vol 24, Iss

2023 Volume 1

Abstract: Background: Melasma is one of the most common disorders of brown hyperpigmentation, which affect primarily the face and later on some other sites of the body , seen most commonly in women during the reproductive period and may seen in men . Many options ... ...

Abstract	Background: Melasma is one of the most common disorders of brown hyperpigmentation, which affect primarily the face and later on some other sites of the body , seen most commonly in women during the reproductive period and may seen in men . Many options are used in the treatment of melasma, most commonly: hydroquinone, tretenoin, corticosteroid, azelic acid, glycolic acid, kojic acid, triaximinic acid, ascorbic acid, intralesional glutathione, and lastly medical procedures, like: microdermabrasion, chemical peel, laser and light therapy. Objective: To evaluate the efficacy and safety of combined therapy (azelic, glycolic and kojic acids) in the treatment of melasma (UNITONE and NEOTONE) . Patients and Methods: A cross-sectional study in which (585) patients complaining of melasma (577 females and 8 males), their age ranged from (17-50) years, with a mean age of 46.15± years. Treated by application of azelic acid (20% cream) for two hours at night, then washed and followed by topical application of combined cream consisted of (5%) glycolic acid and (1%) kojic acid throughout the night and washed in the morning, with application of sun block of ≥50 SPF, and oral ascorbic acid (500mg) tablet twice in the morning and evening . Results: Out of 585, 98% was females with a mean age of (46.15±8) years. Eight percent of the patients of MAIS score-1, (22.05%) of score-2, (51.28%) of score-3 and (18.8%) of score-4. Regarding the response to therapy: (44.78%) of patients showed complete clearance of the disease, (48.85%) with good response, (1.7%) of poor response and (5.47%) showed relapse of the melasma after discontinuation of the therapy, and they were retreated by the same combined formula, (93.75%) of them cleared completely and (6.25%) showed good response. Ninety percent of patients developed a variable degree of irritation, erythema and burning sensation, at the beginning of the treatment and after (10-15) days, most of them tolerated the therapy. Conclusion: Combined therapy of azelic, glycolic and kojic acids was ...
Keywords	Combination therapy ; azelic ; glycolic ; kojic ; ascorbic acids ; MASI ; MSI ; Medicine ; R
Subject code	610 ; 616
Language	English
Publishing date	2023-04-01T00:00:00Z
Publisher	College of medicine/ University of Diyala
Document type	Article ; Online
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Article ; Online: Best management of patients with malignant pericardial effusion: A comparative study between imaging-guided pericardiocentesis and surgical pericardial window.

Baqi, Abdul / Ahmed, Intisar / Shams, Pirbhat

Journal of clinical and translational research

2023 Volume 9, Issue 3, Page(s) 206–211

Abstract: Background: The clinical course of malignancies is frequently complicated by third spacing in body cavities, including pericardial effusion. What remains the optimal management for malignant pericardial effusion is a dilemma.: Aim: We aimed to ... ...

Abstract	Background: The clinical course of malignancies is frequently complicated by third spacing in body cavities, including pericardial effusion. What remains the optimal management for malignant pericardial effusion is a dilemma. Aim: We aimed to compare 30-day outcomes of imaging-guided pericardiocentesis and surgical pericardial window in patients with malignant pericardial effusion. Methods: A retrospective observational study was done at a tertiary care hospital. We reviewed hospital record files of 91 consecutive patients admitted with malignant pericardial effusion from January 2010 to December 2019 and requiring imaging-guided pericardiocentesis or pericardial window. Results: A total of 71 patients were included in the final analysis. Most patients were male (68%). The mean age was 45 years. Hypertension was the most common comorbid condition. Lymphoma or leukemia (39%) was the most common cause of malignant pericardial effusion followed by lung cancer (28%). About 57.7% of patients underwent pericardiocentesis, and the remainder underwent surgical pericardial window (42.3%). The overall procedural success was 97.2%, and the overall mortality was 5.6%. The success rate was similar when pericardiocentesis was compared with the surgical pericardial window ( Conclusion: There is a higher rate of recurrence following isolated pericardiocentesis but a comparable mortality difference between the two procedures. Complication rates can be reduced by improving surgical technique and peri-operative management. Meticulous surgical care, infection precautions, and good glycemic control in this immunocompromised subset can preserve the pericardial window as a better management option. Relevance to patients: Pericardial window is a promising and effective management option for patients with recurrent malignant pericardial effusion, but it comes at the cost of bleeding and infection. More extensive trials are needed to understand better the long-term outcomes of pericardial window or pericardiocentesis in patients with malignant effusion.
Language	English
Publishing date	2023-06-02
Publishing country	Singapore
Document type	Journal Article
ZDB-ID	3019815-X
ISSN	2424-810X ; 2382-6533
ISSN (online)	2424-810X
ISSN	2382-6533
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Article: Evaluation of the efficacy of RF microneedling and oral isotretinoin in comparison with oral isotretionoin alone in the treatment of acne vulgaris.

Hasan, Intisar Ahmed / Mahdi, Zahraa Najah / Obeed, Rana Khalid

Postepy dermatologii i alergologii

2023 Volume 40, Issue 1, Page(s) 111–114

Abstract: Introduction: Acne vulgaris is one of the most common skin illnesses in teenagers, affecting 80% of people aged 11-30 years. Scars on the face are caused by high inflammation, severe acne, physical manipulation of the skin, and delayed treatment.: Aim! ...

Abstract	Introduction: Acne vulgaris is one of the most common skin illnesses in teenagers, affecting 80% of people aged 11-30 years. Scars on the face are caused by high inflammation, severe acne, physical manipulation of the skin, and delayed treatment. Aim: To compare the effectiveness and safety of an automated RF micro needling device and oral isotretinoin with oral isotretinon alone alone for treating active acne. Material and methods: A cross-sectional study of 40 moderate acne sufferers. Twenty patients with active acne were treated with an automated RF microneedling device and isotretinoin 0.5-1 mg/kg. Group B included 20 people with active acne, who were given a single dose of 0.5-1 mg/kg isotretinoin. Results: In this cross-sectional research, 40 acne vulgaris patients were divided into 2 groups: group A: 23.8 ±3.2 years old, 58.95 ±5.5 kg, 13 females, and 7 males. There were 15 females and 5 males in group B: 24.4 ±3.7 years old and weighing 56.4 ±8.46 kg. After 12 weeks, group A shows better global acne assessment scale (GAAS) outcomes than group B than group B. After 6 months, group A showed better results than group B. The GAAS meaning global acne assessment scale did not change after 4-8 weeks of treatment. There was no age or weight difference. Conclusions: Acne vulgaris may be treated with fractional RF microneedling. Active acne treatment with RF microneedling is safe and effective, has a quicker response, causes less scarring, and reduces recurrence.
Language	English
Publishing date	2023-01-16
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2596142-1
ISSN	1642-395X
ISSN	1642-395X
DOI	10.5114/ada.2022.124109
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Article: Transseptal Puncture Through an Interatrial Septum With Lipomatous Hypertrophy: A False Perception of Success and Failure.

Ahmed, Intisar / Qureshi, Aman / Khan, Aamir H

Cureus

2022 Volume 14, Issue 9, Page(s) e29737

Abstract: Transseptal puncture is a standard procedure to access the left atrium during catheter ablation of arrhythmias. It is associated with high success and a meager complication rate in the contemporary era. The potential complications of transseptal puncture ...

Abstract	Transseptal puncture is a standard procedure to access the left atrium during catheter ablation of arrhythmias. It is associated with high success and a meager complication rate in the contemporary era. The potential complications of transseptal puncture include aortic puncture, perforation of the right/left atrial free wall resulting in pericardial effusion/tamponade, and systemic thromboembolism. The dissection of the interatrial septum (IAS) is a rare complication of transseptal puncture, reported in less than 1% of the procedures. We report a case of a dissection of the IAS during an attempted transseptal puncture in a 72-year-old man with lipomatous hypertrophy of the interatrial septum.
Language	English
Publishing date	2022-09-29
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.29737
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Article: Pacemaker Failure to Capture Caused by Electrocautery: A Rare Pacemaker Pulse Generator Change Complication.

Qureshi, Aman / Ahmed, Intisar / Khan, Aamir H

Cureus

2022 Volume 14, Issue 8, Page(s) e28252

Abstract: In the advent of increasing benefits of cardiac devices, more and more implants are being done. Pacing devices reaching the end of service need to be changed. The use of electrocautery (EC) to maintain hemostasis during cardiac device implantation is ... ...

Abstract	In the advent of increasing benefits of cardiac devices, more and more implants are being done. Pacing devices reaching the end of service need to be changed. The use of electrocautery (EC) to maintain hemostasis during cardiac device implantation is efficient and safe. Device makers have variable recommendations for the use of EC. Generally, considered safe, EC has been rarely known to cause device failure. We describe a case of a dual-chamber device, pulse generator change, where EC caused a sudden, unexpected loss of pacing function that lasted for 30 seconds. This case report highlights the gaps in the process of undertaking these high-risk changes.
Language	English
Publishing date	2022-08-22
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.28252
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Article ; Online: Reverse Takotsubo Cardiomyopathy Following A Case Of Suspected Meningoencephalitis And Literature Review.

Shams, Pirbhat / Ahmed, Intisar / Khan, Aamir Hameed

Journal of Ayub Medical College, Abbottabad : JAMC

2022 Volume 33, Issue 4, Page(s) 695–697

Abstract: Reverse Takotsubo cardiomyopathy is a rare variant of stress cardiomyopathy. A 22-year-old male presented with altered mentation and fever. He was intubated due to low Glasgow Coma Scale. CT head plain showed diffuse cerebral oedema. Patient had raised ... ...

Abstract	Reverse Takotsubo cardiomyopathy is a rare variant of stress cardiomyopathy. A 22-year-old male presented with altered mentation and fever. He was intubated due to low Glasgow Coma Scale. CT head plain showed diffuse cerebral oedema. Patient had raised troponin-I and echocardiogram revealed reduced ejection fraction with hyperdynamic apical segments and akinetic basal to mid segments suggestive of reverse Takotsubo cardiomyopathy (rTCM). Association of rTCM with neuropsychiatric disorders such as intracranial/epidural haemorrhages and anorexia nervosa has been defined. However, it is rare to have rTCM with meningoencephalitis.
MeSH term(s)	Adult ; Echocardiography ; Humans ; Male ; Meningoencephalitis/diagnosis ; Takotsubo Cardiomyopathy/diagnosis ; Takotsubo Cardiomyopathy/etiology ; Young Adult
Language	English
Publishing date	2022-02-03
Publishing country	Pakistan
Document type	Case Reports ; Review
ZDB-ID	2192473-9
ISSN	1819-2718 ; 1025-9589
ISSN (online)	1819-2718
ISSN	1025-9589
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Pericardiocentesis Indications and Complications: A Retrospective Observational Study in a Tertiary Care Hospital in Karachi, Pakistan.

Baqi, Abdul / Ahmed, Intisar

Cureus

2020 Volume 12, Issue 8, Page(s) e10102

Abstract: Introduction: Pericardiocentesis is crucial for the diagnosis and management of diseases responsible for significant pericardial effusions. Pericardiocentesis was performed the first time by Riolanus for cardiac tamponade. He described the process of ... ...

Abstract	Introduction: Pericardiocentesis is crucial for the diagnosis and management of diseases responsible for significant pericardial effusions. Pericardiocentesis was performed the first time by Riolanus for cardiac tamponade. He described the process of trephination of the sternum to remove the abnormally accumulated fluid from the pericardial space. However, with the advancement of expertise in echocardiography assisted procedures, echocardiography-guided diagnostic and therapeutic pericardiocentesis is now considered standard clinical practice in the treatment of pericardial effusions. Objectives: We aim to study different causes of pericardial effusion and indications of pericardiocentesis as well as complications associated with it in our population. Methods: This is a retrospective observational study done at Aga Khan University Hospital, Karachi. We reviewed hospital record files of 66 patients admitted to Aga Khan University Hospital from January 2010 to December 2019 who underwent pericardiocentesis. Results: Out of 66 patients, 43 (65.2%) were male. The mean age of the study population was 48.59±18.9 years and 41 (62.1%) of them had underlying active malignancy with hematological malignancies being most common followed by lung carcinoma. In the majority of patients (71.2%), pericardiocentesis was performed at the bedside, and the rest of them (28.8%) underwent pericardiocentesis in the cardiac catheterization laboratory. Of all the patients, 46 (69.7%) underwent pericardiocentesis under echocardiography guidance and 18 (27.3%) required fluoroscopy. Successful pericardiocentesis was performed in 65 (98.5%) of the patients, two (3%) patients developed access site infection and only one (1.5%) patient became hemodynamically unstable while undergoing pericardiocentesis Conclusion: Malignancy, predominantly lymphoma, is the most common cause of pericardial effusion requiring pericardiocentesis. Dyspnea is the most common symptom of presentation with cardiac tamponade. Echocardiography is the commonly used imaging modality for pericardiocentesis. Bedside setting is the most common setting used for pericardiocentesis. Imaging guided pericardiocentesis has a very high success and low complication rate.
Language	English
Publishing date	2020-08-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.10102
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Clinical Presentation, Cardiac Magnetic Resonance Findings, and Prognosis of Patients with Arrhythmogenic Right Ventricular Cardiomyopathy - An Experience from Pakistan.

Ahmed, Intisar / Tipoo, Fateh Ali

Journal of clinical imaging science

2020 Volume 10, Page(s) 48

Abstract: Objectives: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart-muscle disease, characterized by fibro-fatty replacement and ventricular arrhythmias, that primarily affects the right ventricle (RV). We aimed to look at the ... ...

Abstract	Objectives: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart-muscle disease, characterized by fibro-fatty replacement and ventricular arrhythmias, that primarily affects the right ventricle (RV). We aimed to look at the clinical presentation, cardiac magnetic resonance (CMR) imaging findings and prognosis of patients with ARVC in Pakistan. Material and methods: It is a retrospective observational study, 17 consecutive patients with CMR and other findings consistent with ARVC, were enrolled from 2010 to 2019 at a single center. Results: Out of 17 patients, 12 (70.6%) were male with a mean age of 33.5 ± 17.5 years. Family history of sudden cardiac death was present in 3 (17.7%) patients while one (5.9%) patient had family history of ARVC. Syncope was the first presenting symptom in eight (47.1%) patients. On 12 leads ECG, T wave inversion in precordial leads was found in 6 (35.4%) patients, and epsilon wave was present in only 3 (17.7%) patients. On echocardiogram, 13 (76.5%) patients had dilated RV with reduced systolic function. On CMR, majority of patients ( Conclusion: Arrhythmia related events are the main presenting symptoms of ARVC in this region, and left ventricular involvement in ARVC is not rare in this population. The mortality is relatively high, probably due to advanced disease at the time of presentation and less medical facilities available.
Language	English
Publishing date	2020-08-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2601233-9
ISSN	2156-5597 ; 2156-7514
ISSN (online)	2156-5597
ISSN	2156-7514
DOI	10.25259/JCIS_109_2020
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Knowledge, Attitudes and Practices Regarding Use of Local Anaesthetics Among Non-Anaesthesia Healthcare Professionals at Mulago National Referral Hospital.

Abdi, Intisar Ahmed / Kasumba, John Mark / Wabule, Agnes / Nabukenya, Mary T / Kayongo, Joseph / Kyoheirwe, Bernadette / Sheikdon, Abdirizak Abdullahi / Osman, Kamaludin D

Local and regional anesthesia

2024 Volume 17, Page(s) 29–37

Abstract: Introduction: Local anaesthetics (LA) are commonly used in dental and surgical emergency wards by both anaesthesia professionals and non-anaesthesia professionals. Anecdotal evidence shows that non-anaesthesia health-care professionals do not monitor ... ...

Abstract	Introduction: Local anaesthetics (LA) are commonly used in dental and surgical emergency wards by both anaesthesia professionals and non-anaesthesia professionals. Anecdotal evidence shows that non-anaesthesia health-care professionals do not monitor vital signs during the use of local anaesthesia, and there are no standard hospital guidelines on the use of LA and management of LA toxicity by non-anaesthesia professionals. Purpose: This study sought to assess the knowledge, attitudes and practices regarding local anaesthetic use among non-anaesthesia health-care professionals at Mulago National Referral Hospital. Patients and methods: This was a cross-sectional study that utilized a quantitative research approach. The sample size of the study was 43 non-anaesthesia healthcare professionals from the casualty and surgical outpatient wards and Mulago dental ward. Data was collected using a questionnaire and analyzed using STATA 15. Results: Overall, 66.67% of the Specialist, 76.47% of the senior house officers, 100% of medical officers, and 80% of the clinical orthopedic house officers had unsatisfactory levels of knowledge in Mulago casualty and surgical outpatient wards. 20% of the specialist and 16.67% of the senior house officers had unsatisfactory levels of knowledge in Mulago dental ward. 87.5% of the non-anaesthesia health-care professionals do not give a test dose on a routine basis in Mulago casualty and surgical outpatient wards. A total of 63.64% of the non-anaesthesia healthcare professionals in Mulago dental ward do not sterilize the site of injection. Conclusion: Non-anaesthesia health-care professionals had unsatisfactory levels of knowledge, somewhat good practices, and negative attitudes toward LA use.
Language	English
Publishing date	2024-03-08
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2520725-8
ISSN	1178-7112
ISSN	1178-7112
DOI	10.2147/LRA.S428661
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