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  1. Article ; Online: Evaluation of fidaxomicin use in community hospitals after a clinical guideline change at a large health system and opportunities for stewardship.

    Khadem, Tina M / Nguyen, M Hong / Bariola, J Ryan

    Infection control and hospital epidemiology

    2022  Volume 44, Issue 2, Page(s) 312–314

    Abstract: After updating our health system' ... ...

    Abstract After updating our health system's
    MeSH term(s) Humans ; Anti-Bacterial Agents/therapeutic use ; Antimicrobial Stewardship ; Clostridioides ; Clostridioides difficile ; Clostridium Infections/drug therapy ; Fidaxomicin/therapeutic use ; Hospitals, Community
    Chemical Substances Anti-Bacterial Agents ; Fidaxomicin (Z5N076G8YQ)
    Language English
    Publishing date 2022-01-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2021.456
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1714: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Comparison of Indirect Fungal Diagnostic Tests in Patients With Proven Histoplasmosis.

    Krishnan, Gayathri / Power, Margaret / Bariola, J Ryan / Dare, Ryan

    Open forum infectious diseases

    2022  Volume 9, Issue 11, Page(s) ofac609

    Abstract: Background: Histoplasmosis is a common cause of invasive fungal infection in endemic regions and accurate diagnosis is difficult without direct tissue culture or pathology. Indirect fungal antigen testing for various fungal pathogens are typically ... ...

    Abstract Background: Histoplasmosis is a common cause of invasive fungal infection in endemic regions and accurate diagnosis is difficult without direct tissue culture or pathology. Indirect fungal antigen testing for various fungal pathogens are typically performed to assist with diagnostic workup, though cross-reaction can lead to difficulty in interpreting results. We aimed to compare indirect fungal diagnostic tests and evaluate prevalence of positive antigen testing for non-
    Methods: We performed a single-center retrospective review of adult patients with proven histoplasmosis diagnosed by fungal culture and/or cytology from January 2010 to March 2018. Patient demographics, clinical characteristics, and results of fungal antigen testing for
    Results: Fifty-seven of 182 (31.3%) patients reviewed had proven histoplasmosis and presented with acute pulmonary (n = 10), chronic pulmonary (n = 7), and disseminated (n = 40) disease. Forty-one (72%) of these patients were immunosuppressed. Urine
    Conclusions: Noninvasive fungal antigen assays are helpful diagnostic tools; however, given their low specificity, clinicians must be aware of the various clinical presentations of invasive fungal infections and be aware of the limitations of these tests.
    Language English
    Publishing date 2022-11-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofac609
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Impact of a pharmacy-driven MRSA nares screening protocol on vancomycin discontinuation in a tele-antimicrobial stewardship model.

    Trzebucki, Alex M / Davis, Matthew R / McCreary, Erin K / Cuccaro, Susan / Bariola, J Ryan / Khadem, Tina

    Antimicrobial stewardship & healthcare epidemiology : ASHE

    2024  Volume 4, Issue 1, Page(s) e56

    Abstract: A pharmacist-driven protocol for methicillin- ... ...

    Abstract A pharmacist-driven protocol for methicillin-resistant
    Language English
    Publishing date 2024-04-22
    Publishing country England
    Document type Journal Article
    ISSN 2732-494X
    ISSN (online) 2732-494X
    DOI 10.1017/ash.2024.43
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Impact of Rapid Identification and Stewardship Intervention on Coagulase-Negative

    Goshorn, Eli S / Viehman, J Alex / Bariola, J Ryan / Khadem, Tina / Potoski, Brian A / Shields, Ryan K

    Open forum infectious diseases

    2023  Volume 10, Issue 8, Page(s) ofad416

    Abstract: We investigated the impact of rapid diagnostic testing with and without algorithm-based stewardship recommendations on antibiotic use for bloodstream infection with coagulase-negative staphylococci. A significant reduction in antibiotic days of therapy ... ...

    Abstract We investigated the impact of rapid diagnostic testing with and without algorithm-based stewardship recommendations on antibiotic use for bloodstream infection with coagulase-negative staphylococci. A significant reduction in antibiotic days of therapy was achieved in the stewardship intervention group that was not seen with rapid diagnostic testing alone.
    Language English
    Publishing date 2023-07-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofad416
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  5. Article: Development of a Centralized Antimicrobial Stewardship Program Across a Diverse Health System and Early Antimicrobial Usage Trends.

    Khadem, Tina M / Nguyen, M Hong / Mellors, John W / Bariola, J Ryan

    Open forum infectious diseases

    2022  Volume 9, Issue 6, Page(s) ofac168

    Abstract: Background: Expanding antimicrobial stewardship to community hospitals is vital and now required by regulatory agencies. UPMC instituted the Centralized Health system Antimicrobial Stewardship Efforts (CHASE) Program to expand antimicrobial stewardship ... ...

    Abstract Background: Expanding antimicrobial stewardship to community hospitals is vital and now required by regulatory agencies. UPMC instituted the Centralized Health system Antimicrobial Stewardship Efforts (CHASE) Program to expand antimicrobial stewardship to all UPMC hospitals regardless of local resources. For hospitals with few local stewardship resources, we used a model integrating local non-Infectious Diseases (ID) trained pharmacists with centralized ID experts.
    Methods: Thirteen hospitals were included. Eleven were classified as robust (4) or nonrobust (7) depending on local stewardship resources and fulfillment of Centers for Disease Control and Prevention core elements of hospital antimicrobial stewardship. In addition to general stewardship oversight at all UPMC hospitals, the centralized team interacted regularly with nonrobust hospitals for individual patient reviews and local projects. We compared inpatient antimicrobial usage rates at nonrobust versus robust hospitals and at 2 UPMC academic medical centers.
    Results: The CHASE Program expanded in scope between 2018 and 2020. During this period, antimicrobial usage at these 13 hospitals decreased by 16% with a monthly change of -4.7 days of therapy (DOT)/1000 patient days (PD) (95% confidence interval [CI], -5.5 to -3.9;
    Conclusions: Coordinated antimicrobial stewardship can be implemented across a large and diverse health system. Our hybrid model incorporating a central team of experts with local community hospital pharmacists led to usage decreases over 3 years at a rate comparable to that seen in larger hospitals with more established stewardship programs.
    Language English
    Publishing date 2022-04-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofac168
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: In-Person Versus Tele-Infectious Disease (Tele-ID) Care: Is One Better?

    Gupta, Nupur / Bariola, J Ryan / Mellors, John W / Abdel-Massih, Rima C

    Open forum infectious diseases

    2022  Volume 9, Issue 8, Page(s) ofac410

    Abstract: We compared outcomes at 3 community hospitals before and after switching from in-person to a Tele-ID group from an academic medical center. Compared to in-person, Tele-ID received significantly more consultations with similar outcomes for length of ... ...

    Abstract We compared outcomes at 3 community hospitals before and after switching from in-person to a Tele-ID group from an academic medical center. Compared to in-person, Tele-ID received significantly more consultations with similar outcomes for length of hospital stay, transfers, readmission, and mortality. Tele-ID is a suitable alternative for community settings.
    Language English
    Publishing date 2022-08-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofac410
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Bilateral Open Femoral Fracture Complicated by Wound Botulism: A Case Report.

    Reynolds, Kirk A / Young, Daniel R / Bariola, J Ryan / Rudnicki, Stacy A / Gruenwald, J Michael

    JBJS case connector

    2021  Volume 1, Issue 1, Page(s) e3

    Language English
    Publishing date 2021-08-25
    Publishing country United States
    Document type Journal Article
    ISSN 2160-3251
    ISSN (online) 2160-3251
    DOI 10.2106/JBJS.CC.K.00048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Uptake and initial use of novel antimicrobial agents at community hospitals in western Pennsylvania.

    Bariola, J Ryan / Khadem, T / Nguyen, M Hong

    Infection control and hospital epidemiology

    2019  Volume 40, Issue 11, Page(s) 1320–1322

    MeSH term(s) Anti-Infective Agents/therapeutic use ; Drug Utilization/statistics & numerical data ; Hospitals, Community ; Humans ; Infection Control ; Pennsylvania ; Retrospective Studies
    Chemical Substances Anti-Infective Agents
    Language English
    Publishing date 2019-08-22
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2019.220
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1714: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Impact of Clinical Decision Support System Implementation at a Community Hospital With an Existing Tele-Antimicrobial Stewardship Program.

    Khadem, Tina M / Ergen, Howard J / Salata, Heather J / Andrzejewski, Christina / McCreary, Erin K / Abdel Massih, Rima C / Bariola, J Ryan

    Open forum infectious diseases

    2022  Volume 9, Issue 7, Page(s) ofac235

    Abstract: Background: Lack of on-site antimicrobial stewardship expertise is a barrier to establishing successful programs. Tele-antimicrobial stewardship programs (TASPs) utilizing a clinical decision support system (CDSS) can address these challenges.: ... ...

    Abstract Background: Lack of on-site antimicrobial stewardship expertise is a barrier to establishing successful programs. Tele-antimicrobial stewardship programs (TASPs) utilizing a clinical decision support system (CDSS) can address these challenges.
    Methods: This interrupted time series study reports the impact of CDSS implementation (February 2020) within an existing TASP on antimicrobial usage in a community hospital. Segmented regression analysis was used to assess differences in antimicrobial usage from January 2018 through December 2021. Pre- and post-CDSS frequencies of intravenous vs oral antimicrobials, time to optimal therapy (TTOT), pharmacist efficiency (number of documented interventions per month), and percentage of hospitalized patients receiving antimicrobials were compared with descriptive statistics.
    Results: Implementation of a CDSS into an existing TASP was associated with an immediate 11% reduction in antimicrobial usage (level change,
    Conclusions: Implementation of a CDSS within an established TASP at a community hospital resulted in decreased antimicrobial usage, higher rates of oral usage, faster TTOT, and improved pharmacist efficiency.
    Language English
    Publishing date 2022-05-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofac235
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A Multicenter Weighted Lottery to Equitably Allocate Scarce COVID-19 Therapeutics.

    White, Douglas B / McCreary, Erin K / Chang, Chung-Chou H / Schmidhofer, Mark / Bariola, J Ryan / Jonassaint, Naudia N / Persad, Govind / Truog, Robert D / Pathak, Parag / Sonmez, Tayfun / Unver, M Utku

    American journal of respiratory and critical care medicine

    2022  Volume 206, Issue 4, Page(s) 503–506

    MeSH term(s) COVID-19 ; Health Care Rationing ; Humans
    Language English
    Publishing date 2022-05-12
    Publishing country United States
    Document type Letter ; Multicenter Study ; Research Support, N.I.H., Extramural
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202201-0133LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh II Zs.80: Show issues Location:
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