LIVIVO - Search results -

Search results

Result 1 - 10 of total 21

Search options

Article ; Online: Blindness Secondary to Odontogenic Orbital Cellulitis During the COVID-19 Dental Shutdown.

Sheils, Catherine R / Cypen, Sanja G / Tao, Jeremiah P

Ophthalmic plastic and reconstructive surgery

2021 Volume 37, Issue 5, Page(s) e194

MeSH term(s)	Blindness/diagnosis ; Blindness/etiology ; COVID-19 ; Focal Infection, Dental ; Humans ; Orbital Cellulitis/diagnosis ; Orbital Cellulitis/etiology ; Orbital Diseases ; SARS-CoV-2
Language	English
Publishing date	2021-07-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	632830-1
ISSN	1537-2677 ; 0740-9303
ISSN (online)	1537-2677
ISSN	0740-9303
DOI	10.1097/IOP.0000000000002020
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2159: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Vision Loss Associated With Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy.

Han, Michael M / Sheils, Catherine R / Crow, Robert W

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

2021 Volume 42, Issue 2, Page(s) e485–e487

MeSH term(s)	Astrocytes ; Autoantibodies ; Blindness ; Glial Fibrillary Acidic Protein ; Humans
Chemical Substances	Autoantibodies ; Glial Fibrillary Acidic Protein
Language	English
Publishing date	2021-07-26
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1189901-3
ISSN	1536-5166 ; 1070-8022
ISSN (online)	1536-5166
ISSN	1070-8022
DOI	10.1097/WNO.0000000000001323
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1670: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: The impact of amphotericin B-fortified preservation media on donor rim cultures and posttransplant infection.

Hussey, Vincent / Sheils, Catherine R / Salimiaghdam, Nasim / Young, Kirsten / Farid, Marjan

Indian journal of ophthalmology

2022 Volume 70, Issue 9, Page(s) 3294–3297

Abstract: Purpose: To determine the impact of amphotericin B supplementation to donor cornea preservation solutions on the rates of positive donor rim fungal cultures and postkeratoplasty fungal infections.: Methods: This was a retrospective analysis of cases ... ...

Abstract	Purpose: To determine the impact of amphotericin B supplementation to donor cornea preservation solutions on the rates of positive donor rim fungal cultures and postkeratoplasty fungal infections. Methods: This was a retrospective analysis of cases undergoing corneal transplantations at a single tertiary referral center from 2016 to 2021. Patients undergoing corneal transplantations with and without amphotericin B supplementation to the storage media were reviewed for donor rim culture results and postoperative infection. The primary outcome measures were positive donor rim fungal culture results and postkeratoplasty fungal infection. Results: A total of 1238 corneal transplants were analyzed. Of these, 849 were stored in preservation solution without amphotericin B, while 389 had amphotericin B included. There was a lower incidence of positive donor rim fungal cultures in cases with amphotericin B supplementation (1.8%) compared to the cases without amphotericin B (2.9%), although this difference was not statistically significant (P = 0.24). Of the 389 cases with amphotericin B supplementation, one (0.25%) went on to develop clinically significant infection, while three of 849 (0.35%) cases without amphotericin B developed infection. The sample size was too small to determine the effect of amphotericin B on the incidence of postkeratoplasty fungal infection. Conclusion: The addition of amphotericin B to donor cornea preservation solution resulted in a downward trend of positive donor rim fungal cultures and postkeratoplasty fungal infections, although these differences did not reach statistical significance. Further studies with larger sample sizes are necessary to appropriately determine the impact of amphotericin B supplementation in the storage solution on positive donor rims and postkeratoplasty fungal infections.
MeSH term(s)	Amphotericin B ; Cornea ; Corneal Transplantation ; Humans ; Mycoses ; Retrospective Studies ; Tissue Donors
Chemical Substances	Amphotericin B (7XU7A7DROE)
Language	English
Publishing date	2022-09-20
Publishing country	India
Document type	Journal Article
ZDB-ID	187392-1
ISSN	1998-3689 ; 0301-4738
ISSN (online)	1998-3689
ISSN	0301-4738
DOI	10.4103/ijo.IJO_676_22
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 329: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 598: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Orbital Microscopic Polyangiitis With Secondary Angle Closure Due to Uveal Effusion.

Sheils, Catherine R / Cypen, Sanja G / Bhatter, Param / Tao, Jeremiah P

Ophthalmic plastic and reconstructive surgery

2020 Volume 37, Issue 1, Page(s) e33–e35

Abstract: A 63 year-old man presented with 3 weeks of worsening, painless left-sided proptosis, ptosis, and diplopia. Examination of the affected eye revealed normal visual acuity, normal intraocular pressure in the presence of a shallow anterior chamber, grade 1 ... ...

Abstract	A 63 year-old man presented with 3 weeks of worsening, painless left-sided proptosis, ptosis, and diplopia. Examination of the affected eye revealed normal visual acuity, normal intraocular pressure in the presence of a shallow anterior chamber, grade 1 relative afferent pupillary defect, restricted motility in all directions of gaze, and 6 mm of proptosis. Ultrasound biomicroscopy revealed uveal effusions with anterior rotation of the ciliary body causing appositional angle closure. B-scan ultrasonography and MRI demonstrated enhancement of the posterior globe and an infiltrative mass involving the lacrimal gland and multiple extraocular muscles. Laboratory studies revealed positive perinuclear antineutrophil cytoplasmic antibody with elevated myeloperoxidase antibodies, consistent with a diagnosis of microscopic polyangiitis. Biopsy showed nonspecific dacryoadenitis. Intravenous and oral corticosteroids were associated with rapid improvement of all examination findings. The patient was later switched to rituximab steroid-sparing therapy and has shown no recurrence of disease at 3-months follow-up.
MeSH term(s)	Ciliary Body ; Glaucoma, Angle-Closure ; Humans ; Intraocular Pressure ; Male ; Microscopic Polyangiitis ; Middle Aged ; Neoplasm Recurrence, Local ; Ultrasonography
Language	English
Publishing date	2020-05-20
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	632830-1
ISSN	1537-2677 ; 0740-9303
ISSN (online)	1537-2677
ISSN	0740-9303
DOI	10.1097/IOP.0000000000001725
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2159: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Visual Disturbance in a Middle-aged Woman With Non-Small Cell Lung Cancer.

Sheils, Catherine R / Hartmann, Alexander J P W / Kuriyan, Ajay E

JAMA ophthalmology

2018 Volume 136, Issue 6, Page(s) 702–703

MeSH term(s)	Carbazoles/therapeutic use ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/enzymology ; Carcinoma, Non-Small-Cell Lung/secondary ; Choroid Neoplasms/drug therapy ; Choroid Neoplasms/enzymology ; Choroid Neoplasms/secondary ; Female ; Humans ; Lung Neoplasms/drug therapy ; Lung Neoplasms/enzymology ; Lung Neoplasms/pathology ; Magnetic Resonance Imaging ; Middle Aged ; Neoplasm Staging ; Oncogene Proteins, Fusion/metabolism ; Piperidines/therapeutic use ; Protein Kinase Inhibitors/therapeutic use ; Vision Disorders/diagnosis ; Vision Disorders/drug therapy ; Visual Fields
Chemical Substances	CH5424802 ; Carbazoles ; EML4-ALK fusion protein, human ; Oncogene Proteins, Fusion ; Piperidines ; Protein Kinase Inhibitors
Language	English
Publishing date	2018-03-09
Publishing country	United States
Document type	Case Reports ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2701705-9
ISSN	2168-6173 ; 2168-6165
ISSN (online)	2168-6173
ISSN	2168-6165
DOI	10.1001/jamaophthalmol.2017.5776
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ul I Zs.26: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: The Relationship Between Optic Disc Volume, Area, and Frisén Score in Patients With Idiopathic Intracranial Hypertension.

Sheils, Catherine R / Fischer, William S / Hollar, Rachel A / Blanchard, Lisa M / Feldon, Steven E

American journal of ophthalmology

2018 Volume 195, Page(s) 101–109

Abstract: ... at baseline (R: Conclusion: Frisén score fails to reflect the photographic area and OCT volume ...

Abstract	Purpose: To compare measurements of papilledema using fundus photography, optical coherence tomography (OCT), and Frisén score in patients with idiopathic intracranial hypertension (IIH). Design: Retrospective, noncomparative analysis of randomized controlled trial data. Methods: The Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) evaluated weight management and treatment with acetazolamide compared with placebo in patients with IIH and mild visual loss. Among the 126 subjects in the IIHTT OCT substudy, fundus photographs and OCT scans of the optic disc were taken at baseline and at 6 and 12 months after enrollment. Trained readers scored each eye using a modified Frisén scale and measured the area of disc elevation. OCT scans assessed optic nerve head (ONH) volume. Correlations between volume and area were computed for both study and nonstudy eyes. Results: Disc area and ONH volume were positively correlated at baseline (R Conclusion: Frisén score fails to reflect the photographic area and OCT volume of papilledema after treatment with acetazolamide. Clinicians should use caution when using the Frisén scale to monitor the effect of treatment on papilledema over time.
MeSH term(s)	Acetazolamide/therapeutic use ; Adult ; Carbonic Anhydrase Inhibitors/therapeutic use ; Cerebrospinal Fluid ; Double-Blind Method ; Female ; Humans ; Male ; Middle Aged ; Nerve Fibers/pathology ; Optic Disk/pathology ; Organ Size ; Papilledema/diagnosis ; Photography/methods ; Pseudotumor Cerebri/diagnostic imaging ; Pseudotumor Cerebri/drug therapy ; Retinal Ganglion Cells/pathology ; Retrospective Studies ; Tomography, Optical Coherence/methods ; Visual Field Tests
Chemical Substances	Carbonic Anhydrase Inhibitors ; Acetazolamide (O3FX965V0I)
Language	English
Publishing date	2018-08-04
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Multicenter Study ; Randomized Controlled Trial ; Research Support, American Recovery and Reinvestment Act ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	80030-2
ISSN	1879-1891 ; 0002-9394
ISSN (online)	1879-1891
ISSN	0002-9394
DOI	10.1016/j.ajo.2018.07.032
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ul I Zs.39: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Number of children in the household influences respiratory morbidities in children with bronchopulmonary dysplasia in the outpatient setting.

Pediatric pulmonology

2023 Volume 59, Issue 2, Page(s) 314–322

Abstract: Background: Bronchopulmonary dysplasia (BPD), a common complication of prematurity, is associated with outpatient morbidities, including respiratory exacerbations. Daycare attendance is associated with increased rates of acute and chronic morbidities in ...

Abstract	Background: Bronchopulmonary dysplasia (BPD), a common complication of prematurity, is associated with outpatient morbidities, including respiratory exacerbations. Daycare attendance is associated with increased rates of acute and chronic morbidities in children with BPD. We sought to determine if additional children in the household conferred similar risks for children with BPD. Methods: The number of children in the household and clinical outcomes were obtained via validated instruments for 933 subjects recruited from 13 BPD specialty clinics in the United States. Clustered logistic regression models were used to test for associations. Results: The mean gestational age of the study population was 26.5 ± 2.2 weeks and most subjects (69.1%) had severe BPD. The mean number of children in households (including the subject) was 2.1 ± 1.3 children. Each additional child in the household was associated with a 13% increased risk for hospital admission, 13% increased risk for antibiotic use for respiratory illnesses, 10% increased risk for coughing/wheezing/shortness of breath, 14% increased risk for nighttime symptoms, and 18% increased risk for rescue medication use. Additional analyses found that the increased risks were most prominent when there were three or more other children in the household. Conclusions: We observed that additional children in the household were a risk factor for adverse respiratory outcomes. We speculate that secondary person-to-person transmission of respiratory viral infections drives this finding. While this risk factor is not easily modified, measures do exist to mitigate this disease burden. Further studies are needed to define best practices for mitigating this risk associated with household viral transmission.
MeSH term(s)	Infant, Newborn ; Child ; Humans ; Infant ; Bronchopulmonary Dysplasia/epidemiology ; Bronchopulmonary Dysplasia/complications ; Outpatients ; Surveys and Questionnaires ; Infant, Premature ; Hospitalization
Language	English
Publishing date	2023-11-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	632784-9
ISSN	1099-0496 ; 8755-6863
ISSN (online)	1099-0496
ISSN	8755-6863
DOI	10.1002/ppul.26747
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2143: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Evaluation of hospitals participating in the American College of Surgeons National Surgical Quality Improvement Program.

Sheils, Catherine R / Dahlke, Allison R / Kreutzer, Lindsey / Bilimoria, Karl Y / Yang, Anthony D

Surgery

2016 Volume 160, Issue 5, Page(s) 1182–1188

Abstract: Background: The American College of Surgeons National Surgical Quality Improvement Program is well recognized in surgical quality measurement and is used widely in research. Recent calls to make it a platform for national public reporting and pay-for- ... ...

Abstract	Background: The American College of Surgeons National Surgical Quality Improvement Program is well recognized in surgical quality measurement and is used widely in research. Recent calls to make it a platform for national public reporting and pay-for-performance initiatives highlight the importance of understanding which types of hospitals elect to participate in the program. Our objective was to compare characteristics of hospitals participating in the American College of Surgeons National Surgical Quality Improvement Program to characteristics of nonparticipating US hospitals. Methods: The 2013 American Hospital Association and Centers for Medicare & Medicaid Services Healthcare Cost Report Information System datasets were used to compare characteristics and operating margins of hospitals participating in the American College of Surgeons National Surgical Quality Improvement Program to those of nonparticipating hospitals. Results: Of 3,872 general medical and surgical hospitals performing inpatient surgery in the United States, 475 (12.3%) participated in the American College of Surgeons National Surgical Quality Improvement Program. Participating hospitals performed 29.0% of all operations in the United States. Compared with nonparticipating hospitals, American College of Surgeons National Surgical Quality Improvement Program hospitals had a higher mean annual inpatient surgical case volume (6,426 vs 1,874; P < .001) and a larger mean number of hospital beds (420 vs 167; P < .001); participating hospitals were more often teaching hospitals (35.2% vs 4.1%; P < .001), had more quality-related accreditations (P < .001), and had higher mean operating margins (P < .05). States with the highest proportions of hospitals participating in the American College of Surgeons National Surgical Quality Improvement Program had established surgical quality improvement collaboratives. Conclusion: The American College of Surgeons National Surgical Quality Improvement Program hospitals are large teaching hospitals with more quality-related accreditations and financial resources. These findings should be considered when reviewing research studies using the American College of Surgeons National Surgical Quality Improvement Program data, and the findings reinforce that efforts are needed to facilitate participation in surgical quality improvement by all hospital types.
MeSH term(s)	Female ; Hospitals/standards ; Humans ; Male ; Outcome Assessment (Health Care) ; Program Evaluation ; Quality Improvement ; Quality Indicators, Health Care/standards ; Safety-net Providers/standards ; Societies, Medical/organization & administration ; Surgical Procedures, Operative/standards ; United States
Language	English
Publishing date	2016-11
Publishing country	United States
Document type	Comparative Study ; Evaluation Studies ; Journal Article
ZDB-ID	202467-6
ISSN	1532-7361 ; 0039-6060
ISSN (online)	1532-7361
ISSN	0039-6060
DOI	10.1016/j.surg.2016.04.034
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uk I Zs.129: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Long-Term Functional Outcomes at 1-Year After Hospital Discharge in Critically Ill Neonates With Congenital Diaphragmatic Hernia.

O'Hara, Jill E / Buchmiller, Terry L / Bechard, Lori J / Akhondi-Asl, Alireza / Visner, Gary / Sheils, Catherine / Becker, Ronald / Studley, Mollie / Lemire, Lindsay / Mullen, Mary P / Vitali, Sally / Mehta, Nilesh M / Dickie, Belinda / Zalieckas, Jill M / Albert, Ben D

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

2023 Volume 24, Issue 8, Page(s) e372–e381

Abstract: Objectives: Congenital diaphragmatic hernia (CDH) is a birth defect associated with long-term morbidity. Our objective was to examine longitudinal change in Functional Status Scale (FSS) after hospital discharge in CDH survivors.: Design: Single- ... ...

Abstract	Objectives: Congenital diaphragmatic hernia (CDH) is a birth defect associated with long-term morbidity. Our objective was to examine longitudinal change in Functional Status Scale (FSS) after hospital discharge in CDH survivors. Design: Single-center retrospective cohort study. Setting: Center for comprehensive CDH management at a quaternary, free-standing children's hospital. Patients: Infants with Bochdalek CDH were admitted to the ICU between January 2009 and December 2019 and survived until hospital discharge. Interventions: None. Measurements and main results: One hundred forty-two infants (58% male, mean birth weight 3.08 kg, 80% left-sided defects) met inclusion criteria. Relevant clinical data were extracted from the medical record to calculate FSS (primary outcome) at hospital discharge and three subsequent outpatient follow-up time points. The median (interquartile range [IQR]) FSS score at hospital discharge was 8.0 (7.0-9.0); 39 patients (27.5%) had at least moderate impairment (FSS ≥ 9). Median (IQR) FSS at 0- to 6-month ( n = 141), 6- to 12-month ( n = 141), and over 12-month ( n = 140) follow-up visits were 7.0 (7.0-8.0), 7.0 (6.0-8.0), and 6.0 (6.0-7.0), respectively. Twenty-one patients (15%) had at least moderate impairment at over 12-month follow-up; median composite FSS scores in the over 12-month time point decreased by 2.0 points from hospital discharge. Median feeding domain scores improved by 1.0 (1.0-2.0), whereas other domain scores remained without impairment. Multivariable analysis demonstrated right-sided, C- or D-size defects, extracorporeal membrane oxygenation use, cardiopulmonary resuscitation, and chromosomal anomalies were associated with impairment. Conclusions: The majority of CDH survivors at our center had mild functional status impairment (FSS ≤ 8) at discharge and 1-year follow-up; however, nearly 15% of patients had moderate impairment during this time period. The feeding domain had the highest level of functional impairment. We observed unchanged or improving functional status longitudinally over 1-year follow-up after hospital discharge. Longitudinal outcomes will guide interdisciplinary management strategies in CDH survivors.
MeSH term(s)	Infant ; Infant, Newborn ; Child ; Humans ; Male ; Female ; Hernias, Diaphragmatic, Congenital/complications ; Hernias, Diaphragmatic, Congenital/therapy ; Retrospective Studies ; Patient Discharge ; Critical Illness/therapy ; Hospitals
Language	English
Publishing date	2023-04-26
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2052349-X
ISSN	1947-3893 ; 1529-7535
ISSN (online)	1947-3893
ISSN	1529-7535
DOI	10.1097/PCC.0000000000003249
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5600: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 472: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Air quality, Environment and Respiratory Outcomes in Bronchopulmonary Dysplasia, the AERO-BPD cohort study: design and adaptation during the SARS-CoV-2 pandemic.

Ruran, Hana B / Adamkiewicz, Gary / Cunningham, Amparito / Petty, Carter R / Greco, Kimberly F / Gunnlaugsson, Sigfus / Stamatiadis, Natalie / Sierra, Gabriella / Vallarino, Jose / Alvarez, Marty / Hayden, Lystra P / Sheils, Catherine A / Weller, Edie / Phipatanakul, Wanda / Gaffin, Jonathan M

BMJ open respiratory research

2021 Volume 8, Issue 1

Abstract: Introduction: Almost half of all school-age children with bronchopulmonary dysplasia (BPD) have asthma-like symptoms and more suffer from lung function deficits. While air pollution and indoor respiratory irritants are known to affect high-risk ... ...

Abstract	Introduction: Almost half of all school-age children with bronchopulmonary dysplasia (BPD) have asthma-like symptoms and more suffer from lung function deficits. While air pollution and indoor respiratory irritants are known to affect high-risk populations of children, few studies have objectively evaluated environmental contributions to long-term respiratory morbidity in this population. This study aimed to examine the role of indoor environmental exposures on respiratory morbidity in children with BPD. Methods and analysis: The Air quality, Environment and Respiratory Ouctomes in BPD (AERO-BPD) study is a prospective, single-centre observational study that will enrol a unique cohort of 240 children with BPD and carefully characterise participants and their indoor home environmental exposures. Measures of indoor air quality constituents will assess the relationship of nitrogen dioxide (NO Ethics and dissemination: Study protocol was approved by the Boston Children's Hospital Committee on Clinical Investigation. Dissemination will be in the form of peer-reviewed publications and participant information products. Trial registration number: NCT04107701.
MeSH term(s)	Air Pollution/adverse effects ; Air Pollution, Indoor/analysis ; Allergens ; Asthma/epidemiology ; Asthma/physiopathology ; Bronchopulmonary Dysplasia/diagnosis ; Bronchopulmonary Dysplasia/epidemiology ; Bronchopulmonary Dysplasia/physiopathology ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/virology ; Child ; Cohort Studies ; Environmental Exposure/adverse effects ; Environmental Exposure/statistics & numerical data ; Female ; Humans ; Humidity ; Male ; Nitric Oxide/analysis ; Nitrogen Dioxide/analysis ; Particulate Matter/adverse effects ; Prospective Studies ; Respiratory Function Tests/methods ; SARS-CoV-2/genetics ; Temperature
Chemical Substances	Allergens ; Particulate Matter ; Nitric Oxide (31C4KY9ESH) ; Nitrogen Dioxide (S7G510RUBH)
Language	English
Publishing date	2021-02-18
Publishing country	England
Document type	Clinical Trial ; Journal Article ; Observational Study ; Research Support, N.I.H., Extramural
ZDB-ID	2736454-9
ISSN	2052-4439 ; 2052-4439
ISSN (online)	2052-4439
ISSN	2052-4439
DOI	10.1136/bmjresp-2021-000915
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito