Article: The significance of transaminase ratio (AST/ALT) in acute myocardial infarction.
Archives of medical sciences. Atherosclerotic diseases
2020 Volume 5, Page(s) e279–e283
Abstract: Introduction: Fernando De Ritis described the significance of the transaminase (AST/ALT) ratio in 1957, and since then it has been commonly used to screen liver diseases. The liver is sensitive to hemodynamic changes because it receives approximately ... ...
Abstract | Introduction: Fernando De Ritis described the significance of the transaminase (AST/ALT) ratio in 1957, and since then it has been commonly used to screen liver diseases. The liver is sensitive to hemodynamic changes because it receives approximately one-quarter of total cardiac output. We aimed to investigate the AST/ALT ratio changes in patients with acute myocardial infarction without any history of liver diseases in the Chinese Han population. Material and methods: We analyzed a total of 120 patients with acute myocardial infarction admitted to the cardiology department of Zhongnan Hospital of Wuhan University between January 2019 and June 2019. AST/ALT ratio of the first blood test was calculated for all patients. Results: The mean De Ritis ratio (AST/ALT) was higher in patients with ST-segment elevation myocardial infarction (STEMI) (3.2261 ±2.41379) than in non-ST-segment elevation myocardial infarction (NSTEMI) (2.2089 ±1.63177) patients. The difference was statistically significant ( Conclusions: AST/ALT ≥ 2.0 has a strong association with total coronary occlusion. We might rely on this test to predict coronary occlusion without age difference. |
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Language | English |
Publishing date | 2020-12-26 |
Publishing country | Poland |
Document type | Journal Article |
ISSN | 2451-0629 |
ISSN | 2451-0629 |
DOI | 10.5114/amsad.2020.103028 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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