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  1. Article: Morphologic and Morphometric Evaluation of Oblique Popliteal Ligament - A Clinico-Anatomical Study.

    Mehta, Vandana / Dawani, Pooja / Goel, Prabhat

    Maedica

    2022  Volume 17, Issue 3, Page(s) 641–646

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2022-12-20
    Publishing country Romania
    Document type Editorial
    ZDB-ID 2399972-X
    ISSN 2069-6116 ; 1841-9038
    ISSN (online) 2069-6116
    ISSN 1841-9038
    DOI 10.26574/maedica.2022.17.3.641
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  2. Article ; Online: Morphological and morphometric analysis of oblique popliteal ligament in North Indian population: a cadaveric study.

    Kancharla, Emmanuel / Jeph, Renu Baliyan / Ravichandran, Selvalakshmi / Mehta, Vandana / Loh, Hitendra Kumar

    Surgical and radiologic anatomy : SRA

    2024  Volume 46, Issue 4, Page(s) 399–405

    Abstract: Purpose: To study the morphology and the morphometry of the oblique popliteal ligament (OPL).: Methods: Thirty cadaver knees were dissected to study the morphology and morphometry of the OPL. For the measurement of the morphology of the OPL a ... ...

    Abstract Purpose: To study the morphology and the morphometry of the oblique popliteal ligament (OPL).
    Methods: Thirty cadaver knees were dissected to study the morphology and morphometry of the OPL. For the measurement of the morphology of the OPL a standard tape and the vernier callipers were used.
    Result: Out of 30 specimens 14 were Y shaped, 10 were band shaped, and 6 were Z shaped observed. Total length was measured on both the limbs, on the right side it was 4.5 ± 0.4 cm and on the left side 4.5 ± 0.5 cm was recorded. Width at the medial attachment was also measured on both the limbs, on the right side it was 4.6 ± 0.5 cm and on the left side 4.7 ± 0.5 cm was recorded. And width at the lateral attachment was recorded too, on the right side it was 4 ± 0.3 cm and on the left side it was 4 ± 0.3 cm. Width at the midpoint was recorded as on the right side 3.5 ± 0.2 cm and on the left side 3.5 ± 0.2 cm.
    Conclusion: The OPL is a thick ligament that arises as an extension of the semimembranosus, and it exists in various morphology which includes band, Y, Z, complex shapes.
    MeSH term(s) Humans ; Cadaver ; Cerebral Cortex ; Knee Joint/anatomy & histology ; Ligaments, Articular/anatomy & histology ; South Asian People
    Language English
    Publishing date 2024-02-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 632839-8
    ISSN 1279-8517 ; 0930-312X ; 0930-1038
    ISSN (online) 1279-8517
    ISSN 0930-312X ; 0930-1038
    DOI 10.1007/s00276-023-03288-4
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1456: Show issues Location:
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  3. Article ; Online: Injected Breast Materials: Review of Imaging Features and Characteristics.

    Gao, Yukun / Karimova, E Jane / Phillips, Jordana / Fein-Zachary, Valerie / Dialani, Vandana / Mehta, Tejas S / Mehta, Rashmi / Slanetz, Priscilla J

    Journal of breast imaging

    2024  Volume 3, Issue 6, Page(s) 727–739

    Abstract: In the United States, silicone and saline breast implants with their familiar radiologic appearance are the mainstays of breast augmentation. However, less well-known sequelae of unconventional injected materials introduced for cosmetic and noncosmetic ... ...

    Abstract In the United States, silicone and saline breast implants with their familiar radiologic appearance are the mainstays of breast augmentation. However, less well-known sequelae of unconventional injected materials introduced for cosmetic and noncosmetic purposes may also be encountered on breast imaging-for example, free silicone, paraffin and/or oil, polyacrylamide gel, autologous fat, and hyaluronic acid, which are encountered in the setting of breast augmentation. Breast injection of go-yak is not cosmetic but also results in characteristic imaging findings. Breast changes due to extravasation of chemotherapy or interstitial brachytherapy can mimic the appearance of injected noncosmetic materials. Because many of these materials can mimic or obscure imaging findings of breast cancer, it is important to recognize their varied appearances and the limitations of imaging alone in delineating breast injection material from cancer. Given the relatively uncommon incidence of injected materials into the breast, this article aims to review the imaging appearance in order to aid radiologists in maximizing cancer detection and ensuring optimal patient management.
    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ISSN 2631-6129
    ISSN (online) 2631-6129
    DOI 10.1093/jbi/wbab035
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  4. Article ; Online: Ovalbumin/lipopolysaccharide induced vasculitis in rats: a new predictive model.

    Thakur, Vandana R / Mehta, Anita A

    Journal of basic and clinical physiology and pharmacology

    2021  Volume 33, Issue 4, Page(s) 445–455

    Abstract: Objectives: Currently, there are several animal models for vasculitis. Ovalbumin and lipopolysaccharide (OVA, LPS) are well established for causing inflammation and used as an adjunct in the vasculitis induction. However, to date, none has established ... ...

    Abstract Objectives: Currently, there are several animal models for vasculitis. Ovalbumin and lipopolysaccharide (OVA, LPS) are well established for causing inflammation and used as an adjunct in the vasculitis induction. However, to date, none has established the effect of OVA and LPS in disease induction. Therefore, in the present study, an attempt has been made to develop a new animal model for vasculitis using OVA/LPS in rats.
    Methods: A total of 42 Wistar rats were divided randomly into seven groups (n=6/group), normal control, and three different doses (0.5, 1, and 5 mg/kg) of OVA and LPS treated groups. Half of the rats in each group received only intraperitoneal sensitization, while the remaining half rats were additionally subjected to a one-week intranasal challenge.
    Results: Results showed that both OVA/LPS in their respective groups have significantly increased circulating inflammatory cells, C-reactive protein (CRP), Inflammatory cytokines (IL-1β, IL-6, TNF-α), Kidney damage markers (BUN, Creatinine), and liver function enzymes (AST, ALT) in a dose-dependent manner.
    Conclusions: OVA/LPS induced vascular inflammation in a dose-dependent manner. However, the higher (5 mg/kg) dose of ovalbumin and lipopolysaccharide has contributed to severe vascular inflammation through increasing inflammatory cytokines. These findings suggest that OVA/LPS may contribute as a possible model for vasculitis in rats.
    MeSH term(s) Animals ; Cytokines ; Disease Models, Animal ; Inflammation ; Lipopolysaccharides ; Ovalbumin ; Rats ; Rats, Wistar ; Vasculitis
    Chemical Substances Cytokines ; Lipopolysaccharides ; Ovalbumin (9006-59-1)
    Language English
    Publishing date 2021-04-23
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1071737-7
    ISSN 2191-0286 ; 0792-6855 ; 0334-1534
    ISSN (online) 2191-0286
    ISSN 0792-6855 ; 0334-1534
    DOI 10.1515/jbcpp-2020-0200
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3207: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Amalgamation of Toll-Like Receptor and Hypoxic Signaling in Etiology of Preeclampsia.

    Aggarwal, Ruby / Jain, Arun Kumar / Mehta, Vandana / Rath, Gayatri

    Applied immunohistochemistry & molecular morphology : AIMM

    2023  Volume 31, Issue 6, Page(s) 429–437

    Abstract: Inflammation and oxidative stress are involved in the pathogenesis of preeclampsia. Therefore, the aim of this study was to investigate the expression of Toll-like receptor (TLR) (TLR-4, HMGB1, NFκB, IκBα) and hypoxic (HIF-1α, HIF-1β, PHD, pVHL) pathway ... ...

    Abstract Inflammation and oxidative stress are involved in the pathogenesis of preeclampsia. Therefore, the aim of this study was to investigate the expression of Toll-like receptor (TLR) (TLR-4, HMGB1, NFκB, IκBα) and hypoxic (HIF-1α, HIF-1β, PHD, pVHL) pathway proteins in the placenta of preeclamptic pregnant women after 28 weeks of gestational period. A possible association between these 2 pathways was also explored. A total of 194 placental tissues of preeclamptic as well as healthy pregnant women were analyzed by immunohistochemistry. On the basis of gestational age, the samples were divided into 2 groups, I (28-36 wk) and II (36 wk onwards), with 55 and 139 samples in the respective groups. The expression of both TLR (TLR-4, HMGB1, NFκB, IκBα) and hypoxic (HIF-1α, HIF-1β, PHD, pVHL) pathway proteins were significantly modulated in the placental tissues of preeclampsia as compared with control. The 2 pathways were interlinked in preeclampsia. This study highlights the intercorrelation of both TLR and hypoxic signalling pathways that may be a causative factor for the pathophysiology of preeclampsia.
    MeSH term(s) Pregnancy ; Female ; Humans ; Placenta/metabolism ; Pre-Eclampsia/metabolism ; Toll-Like Receptor 4/metabolism ; HMGB1 Protein/metabolism ; NF-KappaB Inhibitor alpha/metabolism
    Chemical Substances Toll-Like Receptor 4 ; HMGB1 Protein ; NF-KappaB Inhibitor alpha (139874-52-5)
    Language English
    Publishing date 2023-05-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1473273-7
    ISSN 1533-4058 ; 1062-3345 ; 1541-2016
    ISSN (online) 1533-4058
    ISSN 1062-3345 ; 1541-2016
    DOI 10.1097/PAI.0000000000001129
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    Zs.A 3783: Show issues Location:
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  6. Article ; Online: Cancer Conspicuity on Low-energy Images of Contrast-enhanced Mammography Compared With 2D Mammography.

    Konstantopoulos, Christina / Mehta, Tejas S / Brook, Alexander / Dialani, Vandana / Mehta, Rashmi / Fein-Zachary, Valerie / Phillips, Jordana

    Journal of breast imaging

    2024  Volume 4, Issue 1, Page(s) 31–38

    Abstract: Objective: Low-energy (LE) images of contrast-enhanced mammography (CEM) have been shown to be noninferior to digital mammography. However, our experience is that LE images are superior to 2D mammography. Our purpose was to compare cancer appearance on ... ...

    Abstract Objective: Low-energy (LE) images of contrast-enhanced mammography (CEM) have been shown to be noninferior to digital mammography. However, our experience is that LE images are superior to 2D mammography. Our purpose was to compare cancer appearance on LE to 2D images.
    Methods: In this IRB-approved retrospective study, seven breast radiologists evaluated 40 biopsy-proven cancer cases on craniocaudal (CC) and mediolateral oblique (MLO) LE images and recent 2D images for cancer visibility, confidence in margins, and conspicuity of findings using a Likert scale. Objective measurements were performed using contrast-to-noise ratio (CNR) estimated from regions of interest placed on tumor and background parenchyma. Reader agreement was evaluated using Fleiss kappa. Per-reader comparisons were performed using Wilcoxon test and overall comparisons used three-way analysis of variance.
    Results: Low-energy images showed improved performance for visibility (CC LE 4.0 vs 2D 3.5, P < 0.001 and MLO LE 3.7 vs 2D 3.5, P = 0.01), confidence in margins (CC LE 3.2 vs 2D 2.8, P < 0.001 and MLO LE 3.1 vs 2D 2.9, P < 0.008), and conspicuity compared to tissue density compared to 2D mammography (CC LE 3.6 vs 2D 3.2, P < 0.001 and MLO LE 3.5 vs 2D 3.2, P < 0.001). The average CNR was significantly higher for LE than for digital mammography (CC 2.1 vs 3.2, P < 0.001 and MLO 2.1 vs 3.4, P < 0.001).
    Conclusion: Our results suggest that cancers may be better visualized on the LE CEM images compared with the 2D digital mammogram.
    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Journal Article
    ISSN 2631-6129
    ISSN (online) 2631-6129
    DOI 10.1093/jbi/wbab085
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  7. Article ; Online: Cutaneous hyalohyphomycosis in an immunocompetent host.

    Mehta, Vandana

    Indian journal of dermatology

    2013  Volume 58, Issue 5, Page(s) 411

    Language English
    Publishing date 2013-09-30
    Publishing country India
    Document type Journal Article
    ZDB-ID 416069-1
    ISSN 1998-3611 ; 0019-5154
    ISSN (online) 1998-3611
    ISSN 0019-5154
    DOI 10.4103/0019-5154.117365
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    Zs.B 817: Show issues Location:
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  8. Article: Endoscopy for assessment of mucosal healing in ulcerative colitis: time bound or response guided?

    Sood, Ajit / Mahajan, Ramit / Singh, Arshdeep / Midha, Vandana / Mehta, Varun

    Intestinal research

    2022  Volume 20, Issue 3, Page(s) 297–302

    Abstract: The timing of colonoscopy in patients with active ulcerative colitis (UC) lacks coherence. The published guidelines and recommendations advocate time-bound colonoscopy in patients with active UC to assess for mucosal healing. However, the practice of ... ...

    Abstract The timing of colonoscopy in patients with active ulcerative colitis (UC) lacks coherence. The published guidelines and recommendations advocate time-bound colonoscopy in patients with active UC to assess for mucosal healing. However, the practice of performing colonoscopies at fixed time frames lacks reasoning. The time to achieve mucosal healing in UC is not uniform across the patient populations and is influenced by the disease severity and efficacy and time to therapeutic response of the drugs being used. Additionally, with the availability of sensitive noninvasive inflammatory biomarkers such as fecal calprotectin, that parallel the disease activity and correlate with mucosal healing, the notion of performing colonoscopy at fixed intervals sounds unjustifiable. The authors express their view that a response-guided colonoscopy (driven by normalization of clinical symptoms and inflammatory biomarkers), rather than a time-bound colonoscopy, would be more logical, apart from being cost-effective and patient-friendly.
    Language English
    Publishing date 2022-02-08
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3018469-1
    ISSN 2288-1956 ; 1598-9100
    ISSN (online) 2288-1956
    ISSN 1598-9100
    DOI 10.5217/ir.2021.00099
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  9. Article ; Online: Effect of soya phosphatidylcholine and possible underlying mechanism on ischemia/reperfusion injury in isolated perfused rat heart: an experimental and computational study.

    Mehta, Anita A / Patel, Purav / Thakur, Vandana R / Beladiya, Jayesh V

    Canadian journal of physiology and pharmacology

    2022  Volume 100, Issue 3, Page(s) 252–258

    Abstract: This study was designed to assess the effect of soya phosphatidylcholine (SPC) against ischemia/reperfusion (I/R) injury and the possible underlying mechanism using experimental and computational studies. I/R injury was induced by global ischemia for 30 ... ...

    Abstract This study was designed to assess the effect of soya phosphatidylcholine (SPC) against ischemia/reperfusion (I/R) injury and the possible underlying mechanism using experimental and computational studies. I/R injury was induced by global ischemia for 30 min followed by reperfusion for 120 min. The perfusion of the SPC was performed for 10 min before inducing global ischemia. In the mechanistic study, the involvement of specific cellular pathways was identified using various inhibitors such as ATP-dependent potassium channel (K
    MeSH term(s) Animals ; Cardiotonic Agents ; Computer Simulation ; In Vitro Techniques ; Male ; Myocardial Reperfusion Injury/diagnosis ; Myocardial Reperfusion Injury/drug therapy ; Myocardial Reperfusion Injury/etiology ; Myocardial Reperfusion Injury/physiopathology ; Phosphatidylcholines/administration & dosage ; Phosphatidylcholines/pharmacology ; Phosphatidylcholines/therapeutic use ; Rats, Wistar ; Toll-Like Receptor 4 ; Rats
    Chemical Substances Cardiotonic Agents ; Phosphatidylcholines ; Tlr4 protein, rat ; Toll-Like Receptor 4
    Language English
    Publishing date 2022-01-06
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 127527-6
    ISSN 1205-7541 ; 0008-4212
    ISSN (online) 1205-7541
    ISSN 0008-4212
    DOI 10.1139/cjpp-2021-0056
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    Zs.A 589: Show issues Location:
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  10. Article ; Online: Cutaneous hyalohyphomycosis in an immunocompetent host

    Vandana Mehta

    Indian Journal of Dermatology, Vol 58, Iss 5, Pp 411-

    2013  Volume 411

    Keywords Medicine ; R ; Dermatology ; RL1-803
    Language English
    Publishing date 2013-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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