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  1. Article ; Online: Epidemiology of invasive group a streptococcal infection in the United States.

    Mulla, Zuber D / Nuwayhid, Ziyad B

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2008  Volume 46, Issue 3, Page(s) 482–483

    MeSH term(s) Fasciitis, Necrotizing/microbiology ; Humans ; Sentinel Surveillance ; Streptococcal Infections/epidemiology ; Streptococcal Infections/mortality ; Streptococcus pyogenes/isolation & purification ; United States/epidemiology
    Language English
    Publishing date 2008-02-01
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1086/526351
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1505: Show issues Location:
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  2. Article: Blunt trauma as a risk factor for group A streptococcal necrotizing fasciitis.

    Nuwayhid, Ziyad B / Aronoff, David M / Mulla, Zuber D

    Annals of epidemiology

    2007  Volume 17, Issue 11, Page(s) 878–881

    Abstract: Purpose: Anecdotal reports suggest that blunt trauma and seemingly innocuous musculoskeletal injuries (e.g., muscle strains) are risk factors for developing necrotizing fasciitis (NF) and myositis caused by group A Streptococcus and other bacteria; ... ...

    Abstract Purpose: Anecdotal reports suggest that blunt trauma and seemingly innocuous musculoskeletal injuries (e.g., muscle strains) are risk factors for developing necrotizing fasciitis (NF) and myositis caused by group A Streptococcus and other bacteria; however, this hypothesis has not been tested in analytic epidemiologic studies of invasive group A streptococcal (GAS) disease. We conducted two case-control studies to determine whether nonpenetrating trauma is a risk factor for either NF or severe cellulitis caused by GAS.
    Methods: A secondary analysis of patients who were hospitalized throughout Florida for invasive GAS disease during a 4-year period was conducted. Two case series were used. The first series comprised patients who had severe GAS cellulitis. The second were patients who had GAS NF. Case-patients were compared to a single control series composed of patients with invasive GAS disease not including either NF or cellulitis (e.g., primary bacteremia, septic arthritis).
    Results: After we adjusted for age, race, and clindamycin usage, GAS NF cases were 5.97 times as likely as controls to have a recent history of blunt trauma (p = 0.04). Patients with severe cellulitis were not more likely than controls to have associated blunt trauma.
    Conclusions: Nonpenetrating trauma is significantly associated with the development of GAS NF.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Case-Control Studies ; Cellulitis/complications ; Cellulitis/etiology ; Clindamycin/therapeutic use ; Fasciitis, Necrotizing/complications ; Fasciitis, Necrotizing/etiology ; Female ; Florida ; Humans ; Logistic Models ; Male ; Middle Aged ; Risk Factors ; Streptococcus pyogenes/pathogenicity ; Wounds, Nonpenetrating/complications
    Chemical Substances Anti-Bacterial Agents ; Clindamycin (3U02EL437C)
    Language English
    Publishing date 2007-11
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1074355-8
    ISSN 1873-2585 ; 1047-2797
    ISSN (online) 1873-2585
    ISSN 1047-2797
    DOI 10.1016/j.annepidem.2007.05.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3225: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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