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  1. Book: Fields virology / 1 / ed.-in-chief David M. Knipe ...

    Fields, Bernard N.

    2001  

    Author's details ed.-in-chief Bernard N. Fields
    Collection Fields virology
    Language English
    Size XIX, 1579, I-72 S. : Ill., graph. Darst.
    Edition 4. ed.
    Publisher Raven Press
    Publishing place New York
    Publishing country United States
    Document type Book
    HBZ-ID HT013105768
    ISBN 0-7817-1832-5 ; 978-0-7817-1832-5
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Fields virology / 2 / ed.-in-chief David M. Knipe ...

    Fields, Bernard N.

    2001  

    Author's details ed.-in-chief Bernard N. Fields
    Collection Fields virology
    Language English
    Size XIX, S. 1581 - 3087, I-72 S. : Ill., graph. Darst.
    Edition 4. ed.
    Publisher Raven Press
    Publishing place New York
    Publishing country United States
    Document type Book
    HBZ-ID HT013105812
    ISBN 0-7817-1832-5 ; 978-0-7817-1832-5
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Online ; E-Book: Divided America, Divided Korea

    Fields, David P. / Lerner, Mitchell B.

    The US and Korea During and after the Trump Years

    (Cambridge Studies in US Foreign Relations Series)

    2024  

    Abstract: Bringing together leading experts on Korea and US-Korean relations, this book provides a nuanced look at the critical relationship between the US and Korea during and after the Trump years. An important study for students and scholars interested in US ... ...

    Author's details edited by David P. Fields and Mitchell B. Lerner
    Series title Cambridge Studies in US Foreign Relations Series
    Abstract Bringing together leading experts on Korea and US-Korean relations, this book provides a nuanced look at the critical relationship between the US and Korea during and after the Trump years. An important study for students and scholars interested in US foreign policy and Korea.
    Keywords Political science ; United States ; Korea
    Subject code 327.730519
    Language English
    Size 1 online resource (266 pages)
    Edition First edition.
    Publisher Cambridge University Press
    Publishing place Cambridge, England
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-009-12140-5 ; 1-009-12228-2 ; 1-009-11926-5 ; 1-009-10057-2 ; 978-1-009-12140-8 ; 978-1-009-12228-3 ; 978-1-009-11926-9 ; 978-1-009-10057-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Voxelotor improves red blood cell functionality in children with sickle cell anaemia: An ancillary study of the HOPE-KIDS 1 trial.

    Chonat, Satheesh / Fields, Earl / Baratz, Hannah / Watt, Amanda / Pochron, Mira / Dixon, Sandy / Tonda, Margaret / Brown, Clark / Archer, David

    EJHaem

    2024  Volume 5, Issue 1, Page(s) 125–130

    Abstract: Introduction: Sickle haemoglobin (HbS) polymerisation perturbs red blood cell (RBC) rheology and drives sickle cell disease (SCD) pathophysiology. Voxelotor is an HbS polymerisation inhibitor that increases haemoglobin (Hb)-oxygen affinity.: Methods/ ... ...

    Abstract Introduction: Sickle haemoglobin (HbS) polymerisation perturbs red blood cell (RBC) rheology and drives sickle cell disease (SCD) pathophysiology. Voxelotor is an HbS polymerisation inhibitor that increases haemoglobin (Hb)-oxygen affinity.
    Methods/results: In this 48-week, prospective, single-centre translational study, 10 children aged 4-11 years with SCD were treated with voxelotor. Improvements in RBC deformability were observed using osmotic/oxygen gradient ektacytometry, with increases in minimal and maximal elongation index and reductions in point of sickling. Increased Hb and reduced markers of haemolysis were also observed.
    Conclusion: These findings suggest that voxelotor treatment is associated with reduced RBC sickling and haemolysis in children with SCD.
    Language English
    Publishing date 2024-01-30
    Publishing country United States
    Document type Journal Article
    ISSN 2688-6146
    ISSN (online) 2688-6146
    DOI 10.1002/jha2.831
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Contemporary orthodontics

    Proffit, William R. / Fields, Henry W. / Larson, Brent E. / Sarver, David M.

    2019  

    Author's details William R. Proffit, DDS, PhD ; Henry W. Fields, Jr., DDS, MS, MSD ; Brent Larson, DDS, MS ; David M. Sarver, DDS, MS
    Keywords Orthodontics
    Subject code 617.643
    Language English
    Size viii, 729 Seiten, Illustationen, 29 cm
    Edition sixth edition
    Publisher Elsevier
    Publishing place Philadelphia, PA
    Publishing country United States
    Document type Book
    Note Zugang zur Online-Ausgabe über Code
    HBZ-ID HT019838384
    ISBN 978-0-323-54387-3 ; 9780323543880 ; 0-323-54387-1 ; 032354388X
    Database Catalogue ZB MED Medicine, Health

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  6. Article ; Online: With age comes resilience.

    Wilson, David B / Fields, Melanie E

    Blood

    2022  Volume 139, Issue 15, Page(s) 2266–2268

    MeSH term(s) Female ; Infant, Newborn ; Pregnancy ; Humans ; Fetus ; Prenatal Care ; Thrombocytopenia
    Language English
    Publishing date 2022-04-13
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2022015821
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Fields virology / 2

    Fields, Bernard N. / Knipe, David M. / Howley, Peter M.

    2013  

    Author's details ed.-in-chief David M. Knipe ; Peter M. Howley
    Collection Fields virology
    Language English
    Size XX S., S. 1283 - 2456, I-82 S. : Ill., graph. Darst., Kt.
    Publisher Wolters Kluwer | Lippincott Williams & Wilkins
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT017729584
    Database Catalogue ZB MED Medicine, Health

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  8. Book: Fields virology / 1

    Fields, Bernard N. / Knipe, David M. / Howley, Peter M.

    2013  

    Author's details ed.-in-chief David M. Knipe ; Peter M. Howley
    Collection Fields virology
    Language English
    Size XX, 1282, I-82 S. : Ill., graph. Darst.
    Publisher Wolters Kluwer | Lippincott Williams & Wilkins
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    Accompanying material Zugang zu Internetausgabe und zusätzlichem Internetmaterial über Code
    HBZ-ID HT017729501
    Database Catalogue ZB MED Medicine, Health

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  9. Article ; Online: A practical guide to the management of phobias.

    Mandich, David V / Fields, Scott A A

    The Journal of family practice

    2020  Volume 69, Issue 1, Page(s) 33–36

    Abstract: When a patient reports symptoms suggestive of phobia, ask questions designed to clarify thoughts and behaviors. A 4-step exposure therapy plan can also help. ...

    Abstract When a patient reports symptoms suggestive of phobia, ask questions designed to clarify thoughts and behaviors. A 4-step exposure therapy plan can also help.
    MeSH term(s) Disease Management ; Humans ; Implosive Therapy/methods ; Phobic Disorders/diagnosis ; Phobic Disorders/psychology ; Phobic Disorders/therapy
    Language English
    Publishing date 2020-02-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197883-4
    ISSN 1533-7294 ; 0094-3509
    ISSN (online) 1533-7294
    ISSN 0094-3509
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Preinjury Frailty Predicts 1-Year Mortality in Older Adults With Traumatic Spine Fractures.

    Fields, Daryl P / Varga, Gregory / Alattar, Ali / Shanahan, Regan / Das, Ashtah / Hamilton, David K / Okonkwo, David O / Kanter, Adam S / Forsythe, Raquel M / Weiner, Debra K

    Neurosurgery

    2024  

    Abstract: Background and objectives: Nearly 30% of older adults presenting with isolated spine fractures will die within 1 year. Attempts to ameliorate this alarming statistic are hindered by our inability to identify relevant risk factors. The primary objective ... ...

    Abstract Background and objectives: Nearly 30% of older adults presenting with isolated spine fractures will die within 1 year. Attempts to ameliorate this alarming statistic are hindered by our inability to identify relevant risk factors. The primary objective of this study was to develop a prediction model that identifies feasible targets to limit 1-year mortality.
    Methods: This retrospective cohort study included 703 older adults (65 years or older) admitted to a level I trauma center with isolated spine fractures, without neural deficit, from January 2013 to January 2018. Multivariable analysis was used to select for independently significant patient demographics, frailty variables, injury metrics, and management decisions to incorporate into distinct logistic regression models predicting 1-year mortality. Variables were considered significant, if P < .05.
    Results: Of the 703 older adults, 199 (28.3%) died after hospital discharge, but within 1 year of index trauma. Risk Analysis Index (RAI; odds ratio [OR]: 1.116; 95% CI: 1.087-1.149; P < .001) and ambulation requiring a cane (OR: 2.601; 95% CI: 1.151-5.799; P = .02) or walker (OR: 4.942; 95% CI: 2.698-9.196; P < .001), ie, frailty variables, were associated with increased odds of 1-year mortality. Spine trauma scales were not associated with 1-year mortality. Longer hospital stays (OR: 1.112; 95% CI: 1.034-1.196; P = .004) and nursing home discharge (OR: 3.881; 95% CI: 2.070-7.378; P < .001) were associated with increased odds, while discharge to rehab (OR: 0.361; 95% CI: 0.155-0.799; P = .014) decreased 1-year mortality odds. A "preinjury" regression model incorporating Risk Analysis Index and ambulation status resulted in an area under receiver operating characteristic curve (AUROCC) of 0.914 (95% CI: 0.863-0.965). A "postinjury" model incorporating Glasgow Coma Scale, hospital stay duration, and discharge disposition resulted in AUROCC of 0.746 (95% CI: 0.642-0.849). Combining elements of the preinjury and postinjury models into an "integrated model" produced an AUROCC of 0.908 (95% CI: 0.852-0.965).
    Conclusion: Preinjury frailty measures are most strongly associated with 1-year mortality outcomes in older adults with isolated spine fractures. Incorporating injury metrics or management decisions did not enhance predictive accuracy. Further work is needed to understand how targeting frailty may reduce mortality.
    Language English
    Publishing date 2024-03-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1227/neu.0000000000002913
    Database MEDical Literature Analysis and Retrieval System OnLINE

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