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  1. Article ; Online: Recent advances in selective mono-/dichalcogenation and exclusive dichalcogenation of C(sp

    Wang, Chang-Sheng / Xu, Yuan / Wang, Shao-Peng / Zheng, Chun-Ling / Wang, Guowei / Sun, Qiao

    Organic & biomolecular chemistry

    2024  Volume 22, Issue 4, Page(s) 645–681

    Abstract: Organochalcogen compounds are prevalent in numerous natural products, pharmaceuticals, agrochemicals, polymers, biological molecules and synthetic intermediates. Direct chalcogenation of C-H bonds has evolved as a step- and atom-economical method for the ...

    Abstract Organochalcogen compounds are prevalent in numerous natural products, pharmaceuticals, agrochemicals, polymers, biological molecules and synthetic intermediates. Direct chalcogenation of C-H bonds has evolved as a step- and atom-economical method for the synthesis of chalcogen-bearing compounds. Nevertheless, direct C-H chalcogenation severely lags behind C-C, C-N and C-O bond formations. Moreover, compared with the C-H monochalcogenation, reports of selective mono-/dichalcogenation and exclusive dichalcogenation of C-H bonds are relatively scarce. The past decade has witnessed significant advancements in selective mono-/dichalcogenation and exclusive dichalcogenation of various C(sp
    Language English
    Publishing date 2024-01-24
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2097583-1
    ISSN 1477-0539 ; 1477-0520
    ISSN (online) 1477-0539
    ISSN 1477-0520
    DOI 10.1039/d3ob01847d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Prediction of a two-dimensional high Curie temperature Weyl nodal line kagome semimetal.

    Li, Jie / Wang, Xiao-Tian / Chen, Ya-Qing / Wei, Yu-Hao / Yuan, Hong-Kuan / Tian, Chun-Ling

    Physical chemistry chemical physics : PCCP

    2024  Volume 26, Issue 4, Page(s) 3092–3100

    Abstract: Kagome lattices may have numerous exotic physical properties, such as stable ferromagnetism and topological states. Herein, combining the particle swarm structure search method with first-principles calculations, we identify a two-dimensional (2D) kagome ...

    Abstract Kagome lattices may have numerous exotic physical properties, such as stable ferromagnetism and topological states. Herein, combining the particle swarm structure search method with first-principles calculations, we identify a two-dimensional (2D) kagome Mo
    Language English
    Publishing date 2024-01-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp03762b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Effect of cardiac rehabilitation care after coronary intervention on cardiac function recovery and negative mood in patients with myocardial infarction.

    Yang, Ming / Huang, Yuan-Tao / Hu, Xi-Wen / Wu, Chun-Ling

    World journal of clinical cases

    2023  Volume 12, Issue 1, Page(s) 59–67

    Abstract: Background: Cardiovascular disease, particularly myocardial infarction (MI) profound impact on patients' quality of life and places a substantial burden on the healthcare and economy systems. Developments in medical technology have led to the emergence ... ...

    Abstract Background: Cardiovascular disease, particularly myocardial infarction (MI) profound impact on patients' quality of life and places a substantial burden on the healthcare and economy systems. Developments in medical technology have led to the emergence of coronary intervention as an essential method for treating MI.
    Aim: To assess the effects of cardiac rehabilitation care on cardiac function recovery and negative emotions in MI after coronary intervention.
    Methods: This study included a total of 180 patients with MI during the period from June 2022 to July 2023. Selected patients were divided into two groups: An observation group, which receiving cardiac rehabilitation care; a control group, which receiving conventional care. By comparing multiple observation indicators such as cardiac function indicators, blood pressure, exercise tolerance, occurrence of adverse cardiac events, and negative emotion scores between the two groups of patients. All the data were analyzed and compared between two groups.
    Results: There were 44 males and 46 females in the observation group with an average age of 36.26 ± 9.88 yr; there were 43 males and 47 females in the control group, with an average age of 40.87 ± 10.5 yr. After receiving the appropriate postoperative nursing measures, the results of the observation group showed significant improvement in several indicators compared with the control group. Indicators of cardiac function, such as left ventricular end-diastolic internal diameter and left ventricular ejection fraction were significantly better in the observation group than in the control group (
    Conclusion: Cardiac rehabilitation care after coronary intervention has a significant positive impact on functional recovery. This emphasizes the importance of cardiac rehabilitation care to improve patient recovery.
    Language English
    Publishing date 2023-11-17
    Publishing country United States
    Document type Journal Article
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v12.i1.59
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Direct C-H Sulfuration: Synthesis of Disulfides, Dithiocarbamates, Xanthates, Thiocarbamates and Thiocarbonates.

    Sun, Qiao / Xu, Yuan / Yang, Liu / Zheng, Chun-Ling / Wang, Guowei / Wang, Hai-Bo / Fang, Zheng / Wang, Chang-Sheng / Guo, Kai

    Chemistry, an Asian journal

    2024  , Page(s) e202400124

    Abstract: In light of the important biological activities and widespread applications of organic disulfides, dithiocarbamates, xanthates, thiocarbamates and thiocarbonates, the continual persuit of efficient methods for their synthesis remains crucial. ... ...

    Abstract In light of the important biological activities and widespread applications of organic disulfides, dithiocarbamates, xanthates, thiocarbamates and thiocarbonates, the continual persuit of efficient methods for their synthesis remains crucial. Traditionally, the preparation of such compounds heavily relied on intricate multi-step syntheses and the use of highly prefunctionalized starting materials. Over the past two decades, the direct sulfuration of C-H bonds has evolved into a straightforward, atom- and step-economical method for the preparation of organosulfur compounds. This review aims to provide an up-to-date discussion on direct C-H disulfuration, dithiocarbamation, xanthylation, thiocarbamation and thiocarbonation, with a special focus on describing scopes and mechanistic aspects. Moreover, the synthetic limitations and applications of some of these methodologies, along with the key unsolved challenges to be addressed in the future are also discussed. The majority of examples covered in this review are accomplished via metal-free, photochemical or electrochemical approaches, which are in alignment with the overraching objectives of green and sustainable chemistry. This comprehensive review aims to consolidate recent advancements, providing valuable insights into the dynamic landscape of efficient and sustainable synthetic strategies for these crucial classes of organosulfur compounds.
    Language English
    Publishing date 2024-02-29
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2233006-9
    ISSN 1861-471X ; 1861-4728
    ISSN (online) 1861-471X
    ISSN 1861-4728
    DOI 10.1002/asia.202400124
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Apple SUMO E3 ligase MdSIZ1 regulates cuticular wax biosynthesis by SUMOylating transcription factor MdMYB30.

    Zhang, Ya-Li / Tian, Yi / Man, Yao-Yang / Zhang, Chun-Ling / Wang, Yi / You, Chun-Xiang / Li, Yuan-Yuan

    Plant physiology

    2023  Volume 191, Issue 3, Page(s) 1771–1788

    Abstract: A key function of SUMOylation is the coordinated modification of numerous proteins to optimize plant growth and resistance to environmental stress. Plant cuticular wax is deposited on the surface of primary plant organs to form a barrier that provides ... ...

    Abstract A key function of SUMOylation is the coordinated modification of numerous proteins to optimize plant growth and resistance to environmental stress. Plant cuticular wax is deposited on the surface of primary plant organs to form a barrier that provides protection against changes in terrestrial environments. Many recent studies have examined cuticular wax biosynthetic pathways and regulation. However, whether SUMOylation is involved in the regulation of cuticle wax deposition at the posttranslational level remains unclear. Here, we demonstrate that a small ubiquitin-like modifier (SUMO) E3 ligase, SAP AND MIZ1 DOMAIN CONTAINING LIGASE1 (MdSIZ1), regulates wax accumulation and cuticle permeability in apple (Malus domestica Borkh), SUMO E2 CONJUGATING ENZYME 1(MdSCE1) physically interacts with MdMYB30, a transcription factor involved in the regulation of cuticle wax accumulation. MdSIZ1 mediates the SUMOylation and accumulation of MdMYB30 by inhibiting its degradation through the 26S proteasome pathway. Furthermore, MdMYB30 directly binds to the β-KETOACYL-COA SYNTHASE 1 (MdKCS1) promoter to activate its expression and promote wax biosynthesis. These findings indicate that the MdSIZ1-MdMYB30-MdKCS1 module positively regulates cuticular wax biosynthesis in apples. Overall, the findings of our study provide insights into the regulation pathways involved in cuticular wax biosynthesis.
    MeSH term(s) Malus/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism ; Ubiquitin/metabolism ; Gene Expression Regulation, Plant ; Waxes/metabolism ; Plant Proteins/genetics ; Plant Proteins/metabolism
    Chemical Substances Transcription Factors ; Ubiquitin-Protein Ligases (EC 2.3.2.27) ; Ubiquitin ; Waxes ; Plant Proteins
    Language English
    Publishing date 2023-01-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 208914-2
    ISSN 1532-2548 ; 0032-0889
    ISSN (online) 1532-2548
    ISSN 0032-0889
    DOI 10.1093/plphys/kiad007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: To compare the influence of blind insertion and up-down optimized glottic exposure manoeuvre on oropharyngeal leak pressure using SaCoVLM™ video laryngeal mask among patients undergoing general anesthesia.

    Yan, Chun-Ling / Zhang, Yi-Qi-Yuan / Chen, Ying / Qv, Zong-Yang / Zuo, Ming-Zhang

    Journal of clinical monitoring and computing

    2022  Volume 37, Issue 2, Page(s) 593–598

    Abstract: To compare the potential influences of blind insertion and up-down optimized glottic exposure manoeuvre on the oropharyngeal leak pressure (OPLP) in using SaCoVLM™ video laryngeal mask (VLM) among patients undergoing general anesthesia. A randomized self- ...

    Abstract To compare the potential influences of blind insertion and up-down optimized glottic exposure manoeuvre on the oropharyngeal leak pressure (OPLP) in using SaCoVLM™ video laryngeal mask (VLM) among patients undergoing general anesthesia. A randomized self-control study controlled was conducted to investigate the effect of two insertion techniques on OPLP. A total of 60 patients (male or female, 18-78 years, BMI 18.0-30.0 kg m
    MeSH term(s) Humans ; Male ; Female ; Laryngeal Masks ; Anesthesia, General/methods ; Intubation, Intratracheal/methods ; Anesthesiology ; Glottis
    Language English
    Publishing date 2022-10-29
    Publishing country Netherlands
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 1418733-4
    ISSN 1573-2614 ; 1387-1307 ; 0748-1977
    ISSN (online) 1573-2614
    ISSN 1387-1307 ; 0748-1977
    DOI 10.1007/s10877-022-00930-1
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  7. Article ; Online: Effectiveness of WeChat-assisted preoperative education to reduce perioperative anxiety in breast cancer patients: a prospective randomized controlled study protocol.

    Xiao, Xiao / Zuo, Yi-Ding / Kuang, Shu-Yu / Liu, Chun-Yuan / Kun-Shao / Wang, Heng / Yan, Si-Yu / Yu, Feng / Xu, Yan / Zhou, Li / Jiang, Chun-Ling

    Trials

    2024  Volume 25, Issue 1, Page(s) 231

    Abstract: Background: Breast cancer is the most prevalent cancer among women globally, and surgical procedures continue to be the primary treatment. However, over 50% of patients experience preoperative anxiety due to the unknown and fear associated with surgery. ...

    Abstract Background: Breast cancer is the most prevalent cancer among women globally, and surgical procedures continue to be the primary treatment. However, over 50% of patients experience preoperative anxiety due to the unknown and fear associated with surgery. Although drug therapy is commonly used to address this anxiety, its side effects have led to a heated debate regarding its effectiveness. Consequently, non-pharmacological therapies, such as preoperative education, have emerged as an alternative approach to alleviate anxiety. WeChat, a widely popular social media platform, offers a public platform that can potentially be utilized for effective preoperative education. This study aims to evaluate the use of WeChat public platform as a tool for preoperative education in patients undergoing breast surgery.
    Methods: This is a prospective, randomized, and controlled trial will involve 392 adult women scheduled for breast cancer resection. Participants will be randomly assigned to either the WeChat education group or the regular group. In addition to regular preoperative visits, the WeChat education group will also watch science videos through the WeChat public platform. The regular group will only receive education from ward nurses during preoperative visits. The primary outcome measure will be the incidence of preoperative anxiety, defined by scores of the State Anxiety Inventory (SAI) exceeding 40 points. Secondary outcome measures include the incidence of severe anxiety (SAI > 44) on the day before surgery, incidence of anxiety 72 h after surgery, incidence of severe anxiety 72 h after surgery, NRS scores for pain at rest and during activity 24, 48, and 72 h after surgery, incidence of nausea and vomiting within 24 h after surgery, subjective sleep score at 1 week postoperatively, quality of life QoR-15 scores at 1 and 3 months postoperatively, incidence of chronic pain at 3 months postoperatively, bowel function recovery, length of hospital stay, and hospitalization expenses.
    Discussion: This is the first clinical trial to investigate the use of WeChat public platform for delivering preoperative education on perioperative anxiety in breast cancer patients. By utilizing the renowned WeChat public platform, our study aims to improve patient outcomes by providing video education that explains the disease, surgery, and anesthesia in a more accessible manner, thereby reducing the incidence of perioperative anxiety. If our hypothesis is confirmed, this non-pharmacological approach can be universally acknowledged as a cost-effective and practical method in clinical care. Its application can also be extended to other medical fields beyond breast cancer.
    Trial registration: ClinicalTrials.gov, NCT05291494. Registered on 29 December 2021.
    MeSH term(s) Adult ; Humans ; Female ; Quality of Life ; Breast Neoplasms/surgery ; Prospective Studies ; Anxiety/diagnosis ; Anxiety/etiology ; Anxiety/prevention & control ; Preoperative Care/methods ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2024-04-03
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1745-6215
    ISSN (online) 1745-6215
    ISSN 1468-6694 ; 1745-6215
    DOI 10.1186/s13063-024-08071-3
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  8. Article ; Online: LINC00511 is associated with the malignant status and promotes cell proliferation and motility in cervical cancer.

    Yu, Chun-Ling / Xu, Xiao-Ling / Yuan, Fang

    Bioscience reports

    2019  Volume 39, Issue 9

    Abstract: LINC00511 is a newly identified lncRNA that is up-regulated in many types of human cancers and may serve as an oncogenic lncRNA. However, there was no report about the role of LINC00511 in cervical cancer. Therefore, we investigated the clinical value of ...

    Abstract LINC00511 is a newly identified lncRNA that is up-regulated in many types of human cancers and may serve as an oncogenic lncRNA. However, there was no report about the role of LINC00511 in cervical cancer. Therefore, we investigated the clinical value of LINC00511 in cervical cancer patients via analyzing the correlation between LINC00511 expression and clinicopathological features. Moreover, we performed loss-of-function study to estimate the effect of LINC00511 on cervical cancer cell proliferation, migration, and invasion. In our study, we found LINC00511 expression levels were increased in cervical cancer tissues and cell lines compared with adjacent normal tissues and normal cervical epithelial cell line, respectively. High LINC00511 expression was correlated with advanced clinical stage, large tumor size, histological type of adenocarcinoma, and present lymph node metastasis, distant metastasis, and poor overall survival in cervical cancer patients. The
    MeSH term(s) Biomarkers, Tumor/genetics ; Carcinogenesis/genetics ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Female ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Lymphatic Metastasis/genetics ; Lymphatic Metastasis/pathology ; Middle Aged ; Neoplasm Invasiveness/genetics ; Neoplasm Invasiveness/pathology ; Neoplasm Staging ; RNA, Long Noncoding/genetics ; Uterine Cervical Neoplasms/genetics ; Uterine Cervical Neoplasms/pathology
    Chemical Substances Biomarkers, Tumor ; RNA, Long Noncoding
    Language English
    Publishing date 2019-09-13
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 764946-0
    ISSN 1573-4935 ; 0144-8463
    ISSN (online) 1573-4935
    ISSN 0144-8463
    DOI 10.1042/BSR20190903
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  9. Article: Effect of age on postural performance and control strategies during changes in visual input and dual-tasking stances.

    Chen, Hui-Ya / Chen, Han-Yu / Chen, Bing-Hong / Lou, Shu-Zon / Chen, Li-Yuan / Lin, Chun-Ling

    Heliyon

    2023  Volume 9, Issue 8, Page(s) e18472

    Abstract: Background: With age, people begin to experience deterioration in standing balance, especially when sensory input is suddenly removed or added. Here, we sought to explore the effects of age on postural performance and postural control strategies.: ... ...

    Abstract Background: With age, people begin to experience deterioration in standing balance, especially when sensory input is suddenly removed or added. Here, we sought to explore the effects of age on postural performance and postural control strategies.
    Methods: The convenience sample consisted of 15 young, 10 middle-aged, and 14 elderly healthy adults. They were instructed to stand with their feet together in four randomly administered conditions involving visual input removal/addition and single-/dual-tasking. Dual-tasking involved continuous subtraction by 3s.
    Results: Postural sway displacement in the two older groups seemed larger than that in the younger group; however, neither the main effect of group (F
    Conclusions: In healthy older individuals, age-related changes were observed in control strategies used to maintain standing balance upon changes in visual input. The dual-task paradigm induced the use of an ankle-stiffening strategy in middle-aged and elderly adults.
    Language English
    Publishing date 2023-07-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e18472
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  10. Article ; Online: The Association Between Subjective Mental Impairment and Objective Cognitive Performance in Non-Demented, Very Mild and Mild Demented Individuals.

    Huang, Ling-Chun / Yang, Yuan-Han

    American journal of Alzheimer's disease and other dementias

    2023  Volume 38, Page(s) 15333175231196061

    Abstract: Objectives: Explore associations between subjective mental impairment, objective cognitive performance, and subsequent decline in older individuals with different cognitive statuses in Taiwan.: Methods: Use self-reported questionnaire and cognitive ... ...

    Abstract Objectives: Explore associations between subjective mental impairment, objective cognitive performance, and subsequent decline in older individuals with different cognitive statuses in Taiwan.
    Methods: Use self-reported questionnaire and cognitive abilities screening instrument to assess subjective and objective cognitive function. Categorize participants as reporters or non-reporters based on subjective reports. Conduct t-tests and regression analysis.
    Results: 206 participants were assessed: 99 cognitively intact (CI), 44 very mild dementia, and 63 mild dementia. In the CI group, reporters in memory, orientation, daily life, community affairs, and judgement domains performed worse than non-reporters. In very mild dementia group, reporters in memory and personality domains performed better than non-reporters. No association found between subjective reports and 1-year cognitive decline in dementia groups.
    Conclusion: Association between subjective impairment and objective performance differs in CI and very mild dementia groups. Subjective reports do not predict 1-year cognitive decline in dementia patients. Longer follow-up studies needed.
    MeSH term(s) Humans ; Aged ; Cognitive Dysfunction/diagnosis ; Dementia ; Cognition ; Follow-Up Studies ; Surveys and Questionnaires ; Neuropsychological Tests
    Language English
    Publishing date 2023-08-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1283069-0
    ISSN 1938-2731 ; 0895-5336 ; 1082-5207 ; 1533-3175
    ISSN (online) 1938-2731
    ISSN 0895-5336 ; 1082-5207 ; 1533-3175
    DOI 10.1177/15333175231196061
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