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Article ; Online: A welcomed invitation: The feasibility of Trauma Adapted Yoga on a psychiatric inpatient adolescent unit.

Khoury, Nayla M / Carbone, Stephanie / Cote, John / LePage, Emily / George, Susan / Zhang-James, Yanli / Duquette, Jacquelynn / Hagen, Kathryn

General hospital psychiatry

2024 Volume 88, Page(s) 81–82

MeSH term(s)	Humans ; Adolescent ; Yoga/psychology ; Inpatients ; Feasibility Studies ; Meditation
Language	English
Publishing date	2024-02-10
Publishing country	United States
Document type	Letter
ZDB-ID	392299-6
ISSN	1873-7714 ; 0163-8343
ISSN (online)	1873-7714
ISSN	0163-8343
DOI	10.1016/j.genhosppsych.2024.02.005
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: High-level nitrofurantoin resistance in a clinical isolate of

Hussein, Maytham / Sun, Zetao / Hawkey, Jane / Allobawi, Rafah / Judd, Louise M / Carbone, Vincenzo / Sharma, Rajnikant / Thombare, Varsha / Baker, Mark / Rao, Gauri G / Li, Jian / Holt, Kathryn E / Velkov, Tony

mSystems

2023 Volume 9, Issue 1, Page(s) e0097223

Abstract: Nitrofurantoin is a commonly used chemotherapeutic agent in the treatment of uncomplicated urinary tract infections caused by the problematic multidrug resistant Gram-negative ... ...

Abstract	Nitrofurantoin is a commonly used chemotherapeutic agent in the treatment of uncomplicated urinary tract infections caused by the problematic multidrug resistant Gram-negative pathogen
MeSH term(s)	Humans ; Nitrofurantoin/pharmacology ; Klebsiella pneumoniae/genetics ; Klebsiella Infections/drug therapy ; Drug Resistance, Multiple, Bacterial/genetics ; Anti-Bacterial Agents/metabolism ; Urinary Tract Infections/drug therapy ; Genomics ; Nitroreductases/genetics ; Riboflavin/metabolism ; RNA, Transfer/metabolism
Chemical Substances	Nitrofurantoin (927AH8112L) ; Anti-Bacterial Agents ; Nitroreductases (EC 1.7.-) ; Riboflavin (TLM2976OFR) ; RNA, Transfer (9014-25-9)
Language	English
Publishing date	2023-12-11
Publishing country	United States
Document type	Journal Article
ISSN	2379-5077
ISSN (online)	2379-5077
DOI	10.1128/msystems.00972-23
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Article ; Online: Stroke Alters the Function of Enteric Neurons to Impair Smooth Muscle Relaxation and Dysregulates Gut Transit.

Kumar, Kathryn Prame / Wilson, Jenny L / Nguyen, Huynh / McKay, Liam D / Wen, Shu Wen / Sepehrizadeh, Tara / de Veer, Michael / Rajasekhar, Pradeep / Carbone, Simona E / Hickey, Michael J / Poole, Daniel P / Wong, Connie H Y

Journal of the American Heart Association

2024 Volume 13, Issue 3, Page(s) e033279

Abstract: Background: Gut dysmotility is common after ischemic stroke, but the mechanism underlying this response is unknown. Under homeostasis, gut motility is regulated by the neurons of the enteric nervous system that control contractile/relaxation activity of ...

Abstract	Background: Gut dysmotility is common after ischemic stroke, but the mechanism underlying this response is unknown. Under homeostasis, gut motility is regulated by the neurons of the enteric nervous system that control contractile/relaxation activity of muscle cells in the gut wall. More recently, studies of gut inflammation revealed interactions of macrophages with enteric neurons are also involved in modulating gut motility. However, whether poststroke gut dysmotility is mediated by direct signaling to the enteric nervous system or indirectly via inflammatory macrophages is unknown. Methods and results: We examined these hypotheses by using a clinically relevant permanent intraluminal midcerebral artery occlusion experimental model of stroke. At 24 hours after stroke, we performed in vivo and ex vivo gut motility assays, flow cytometry, immunofluorescence, and transcriptomic analysis. Stroke-induced gut dysmotility was associated with recruitment of muscularis macrophages into the gastrointestinal tract and redistribution of muscularis macrophages away from myenteric ganglia. The permanent intraluminal midcerebral artery occlusion model caused changes in gene expression in muscularis macrophages consistent with an altered phenotype. While the size of myenteric ganglia after stroke was not altered, myenteric neurons from post-permanent intraluminal midcerebral artery occlusion mice showed a reduction in neuronal nitric oxide synthase expression, and this response was associated with enhanced intestinal smooth muscle contraction ex vivo. Finally, chemical sympathectomy with 6-hydroxydopamine prevented the loss of myenteric neuronal nitric oxide synthase expression and stroke-induced slowed gut transit. Conclusions: Our findings demonstrate that activation of the sympathetic nervous system after stroke is associated with reduced neuronal nitric oxide synthase expression in myenteric neurons, resulting in impaired smooth muscle relaxation and dysregulation of gut transit.
MeSH term(s)	Mice ; Animals ; Nitric Oxide Synthase Type I/genetics ; Nitric Oxide Synthase Type I/metabolism ; Enteric Nervous System/metabolism ; Neurons/physiology ; Muscle Relaxation ; Stroke/metabolism
Chemical Substances	Nitric Oxide Synthase Type I (EC 1.14.13.39)
Language	English
Publishing date	2024-01-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2653953-6
ISSN	2047-9980 ; 2047-9980
ISSN (online)	2047-9980
ISSN	2047-9980
DOI	10.1161/JAHA.123.033279
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book: Borna disease virus and its role in neurobehavioral disease

Carbone, Kathryn M

2002

Author's details	edited by Kathryn M. Carbone
Language	English
Size	XIV, 233 S, Ill., graph. Darst, 24 cm
Publisher	ASM Press
Publishing place	Washington, DC
Document type	Book
Note	BDV: spanning a century of science / Keizo Tomonaga and Kathryn M. Carbone -- Borna disease virus: molecular virology / Masahiko Kishi, Keizo Tomonaga, Patrick Lai, and Juan Carlos de la Torre -- Laboratory diagnosis / Christian Suder, Tetsuya Mizutani and Kazunari Yamaguchi -- Epidemiology and infection of natural animal hosts / Kazuyoshi Ikuta, Katsuro Hagiwara, Hiroyuki Taniyama, and Norbert Nowotny -- Experimental infection: pathogenesis of neurobehavioral disease / Mikhail V. Pletnikov, Daniel Gonzalez-Dunia, and Lothar Stitz -- Human BDV infection / Oliver Planz, Karl A. Bechter, and Martin Schwemmle ; Includes bibliographical references and index
ISBN	155581235X ; 9781555812355
Database	Special collection on veterinary medicine and general parasitology

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Article ; Online: Applying an Innovative Model of Disaster Resilience at the Neighborhood Level : The COPEWELL New York City Experience.

Slemp, Catherine C / Sisco, Sarah / Jean, Marc C / Ahmed, Munerah S / Kanarek, Norma F / Erös-Sarnyai, Monika / Gonzalez, Ingrid A / Igusa, Takeru / Lane, Kathryn / Tirado, Fernando P / Tria, Maryellen / Lin, Sen / Martins, Valter N / Ravi, Sanjana / Kendra, James M / Carbone, Eric G / Links, Jonathan M

Public health reports (Washington, D.C. : 1974)

2020 Volume 135, Issue 5, Page(s) 565–570

Abstract: Community resilience is a community's ability to maintain functioning (ie, delivery of services) during and after a disaster event. The Composite of Post-Event Well-Being (COPEWELL) is a system dynamics model of community resilience that predicts a ... ...

Abstract	Community resilience is a community's ability to maintain functioning (ie, delivery of services) during and after a disaster event. The Composite of Post-Event Well-Being (COPEWELL) is a system dynamics model of community resilience that predicts a community's disaster-specific functioning over time. We explored COPEWELL's usefulness as a practice-based tool for understanding community resilience and to engage partners in identifying resilience-strengthening strategies. In 2014, along with academic partners, the New York City Department of Health and Mental Hygiene organized an interdisciplinary work group that used COPEWELL to advance cross-sector engagement, design approaches to understand and strengthen community resilience, and identify local data to explore COPEWELL implementation at neighborhood levels. The authors conducted participant interviews and collected shared experiences to capture information on lessons learned. The COPEWELL model led to an improved understanding of community resilience among agency members and community partners. Integration and enhanced alignment of efforts among preparedness, disaster resilience, and community development emerged. The work group identified strategies to strengthen resilience. Searches of neighborhood-level data sets and mapping helped prioritize communities that are vulnerable to disasters (eg, medically vulnerable, socially isolated, low income). These actions increased understanding of available data, identified data gaps, and generated ideas for future data collection. The COPEWELL model can be used to drive an understanding of resilience, identify key geographic areas at risk during and after a disaster, spur efforts to build on local metrics, and result in innovative interventions that integrate and align efforts among emergency preparedness, community development, and broader public health initiatives.
MeSH term(s)	Disasters/statistics & numerical data ; Humans ; Models, Theoretical ; New York City ; Residence Characteristics/statistics & numerical data ; Resilience, Psychological ; Social Capital ; Stress, Psychological
Language	English
Publishing date	2020-07-31
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID	120953-x
ISSN	1468-2877 ; 0033-3549
ISSN (online)	1468-2877
ISSN	0033-3549
DOI	10.1177/0033354920938012
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Un I Zs.150: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 479: Show issues

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Article: Storage Stability Study of Salicylate-based Poly(anhydride-esters).

Deronde, Brittany M / Carbone, Ashley L / Uhrich, Kathryn E

Polymer degradation and stability

2010 Volume 95, Issue 9, Page(s) 1778–1782

Abstract: Storage stability was evaluated on a biodegradable salicylate-based poly(anhydride-ester) to elucidate the effects of storage conditions over time. The hydrolytically labile polymer samples were stored in powdered form at five relevant storage ... ...

Abstract	Storage stability was evaluated on a biodegradable salicylate-based poly(anhydride-ester) to elucidate the effects of storage conditions over time. The hydrolytically labile polymer samples were stored in powdered form at five relevant storage temperatures (-12 °C, 4 °C, 27 °C, 37 °C, 50 °C) and monitored over four weeks for changes in color, glass transition temperature, molecular weight, and extent of hydrolysis. Samples stored at lower temperatures remained relatively constant with respect to bond hydrolysis and molecular weight. Whereas, samples stored at higher temperatures displayed significant hydrolysis. For hydrolytically degradable polymers, such as these poly(anhydride-esters), samples are best stored at low temperatures under an inert atmosphere.
Language	English
Publishing date	2010-11-30
Publishing country	England
Document type	Journal Article
ZDB-ID	1502217-1
ISSN	0141-3910
ISSN	0141-3910
DOI	10.1016/j.polymdegradstab.2010.05.008
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Association of vitamin D with incident glaucoma: findings from the Women's Health Initiative.

Carbone, Laura D / Johnson, Karen / Larson, Joseph C / Thomas, Fridtjof / Wactawski-Wende, Jean / Bollinger, Kathryn / Chen, Zhao / Watsky, Mitchell

Journal of investigative medicine : the official publication of the American Federation for Clinical Research

2021

Abstract: The relationship between vitamin D and glaucoma is controversial. The objective of this study was to examine women from the Women's Health Initiative (WHI) to determine if there is an association between vitamin D and incident glaucoma in postmenopausal ... ...

Abstract	The relationship between vitamin D and glaucoma is controversial. The objective of this study was to examine women from the Women's Health Initiative (WHI) to determine if there is an association between vitamin D and incident glaucoma in postmenopausal women. We examined the association between dietary vitamin D intake, vitamin D supplements and serum 25 hydroxyvitamin D (25(OH)D) levels and the risk of developing glaucoma. 143,389 postmenopausal women from the WHI including a subset with serum 25(OH) D measurements were examined to determine the association of dietary, supplemental and serum levels of vitamin D to the development of glaucoma. Dietary intakes of vitamin D, use of vitamin D supplements and serum levels of 25(OH) D were predictors examined for the main outcome of incident glaucoma. In multivariable models adjusted for demographic, clinical variables and medication use, dietary vitamin D, vitamin D supplements, total vitamin D intake (diet plus supplements) and serum 25 (OH) D measurements were not significantly associated with incident glaucoma. In the CaD placebo-controlled intervention clinical trial, there was also no association in the active intervention arm with glaucoma. We conclude that dietary vitamin D intake, supplements and serum levels are not significantly related to the risk of developing glaucoma in postmenopausal women.
Language	English
Publishing date	2021-01-11
Publishing country	England
Document type	Journal Article
ZDB-ID	1217870-6
ISSN	1708-8267 ; 0009-9279 ; 1081-5589
ISSN (online)	1708-8267
ISSN	0009-9279 ; 1081-5589
DOI	10.1136/jim-2020-001645
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Zs.A 307: Show issues

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Book: Borna disease virus and its role in neurobehavioral disease

Carbone, Kathryn M

2002

Author's details	edited by Kathryn M. Carbone
Keywords	Borna disease. ; Borna disease virus. ; Neurobehavioral disorders/Etiology. ; Central nervous system/Infections.
Language	English
Size	xiv, 233 p., [4] p. of plates :, ill. (some col.) ;, 24 cm.
Publisher	ASM Press
Publishing place	Washington, D.C
Document type	Book
ISBN	155581235X ; 9781555812355
Database	NAL-Catalogue (AGRICOLA)

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Book: Borna disease virus and its role in neurobehavioral disease

Carbone, Kathryn M

2002

Author's details	edited by Kathryn M. Carbone
MeSH term(s)	Borna Disease/virology ; Borna disease virus/pathogenicity ; Central Nervous System Viral Diseases/physiopathology
Language	English
Size	xiv, 233 p. :, ill.
Publisher	ASM Press
Publishing place	Washington, D.C
Document type	Book
ISBN	9781555812355 ; 155581235X
Database	Catalogue of the US National Library of Medicine (NLM)

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Book ; Online: Borna disease virus and its role in neurobehavioral disease

Carbone, Kathryn M

2002

Title variant	Rueckent.: Borna disease virus ; Borna disease virus
Author's details	edited by Kathryn M. Carbone
MeSH term(s)	Borna Disease/virology ; Borna disease virus/pathogenicity ; Central Nervous System Viral Diseases/physiopathology
Keywords	Borna disease ; Borna disease virus ; Central nervous system/Infections ; Neurobehavioral disorders/Etiology
Language	English
Size	Online-Ressource (xiv, 233 pages), illustrations (some color)
Publisher	ASM Press
Publishing place	Washington, D.C
Document type	Book ; Online
Note	Includes bibliographical references and index ; Use copy Restrictions unspecified star MiAaHDL
ISBN	1555817904 ; 155581235X ; 9781555812355 ; 9781555817909
Database	Former special subject collection: coastal and deep sea fishing

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