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  1. Book: Neuroinflammation, gut-brain axis and immunity in neuropsychiatric disorders

    Kim, Yong-Ku

    (Advances in experimental medicine and biology ; 1400)

    2023  

    Author's details Yong-Ku Kim editor
    Series title Advances in experimental medicine and biology ; 1400
    Collection
    Keywords Mental illness/Pathophysiology ; Mental illness/Chemotherapy ; Cytokines ; Neuroglia ; Inflammation
    Subject code 616.89
    Language English
    Size xvii, 559 Seiten, Illustrationen, 24 cm
    Publisher Springer
    Publishing place Singapore
    Publishing country Singapore
    Document type Book
    HBZ-ID HT021740510
    ISBN 978-981-19-7375-8 ; 9789811973765 ; 981-19-7375-X ; 9811973768
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Major depressive disorder

    Kim, Yong-Ku

    rethinking and understanding recent discoveries

    (Advances in experimental medicine and biology ; 1305)

    2021  

    Author's details Yong-Ku Kim editor
    Series title Advances in experimental medicine and biology ; 1305
    Collection
    Language English
    Size xi, 563 Seiten, Illustrationen, Diagramme
    Publisher Springer
    Publishing place Singapore
    Publishing country Singapore
    Document type Book
    HBZ-ID HT020901525
    ISBN 978-981-336-043-3 ; 9789813360440 ; 981-336-043-7 ; 9813360445
    Database Catalogue ZB MED Medicine, Health

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  3. Book: Anxiety disorders

    Kim, Yong-Ku

    rethinking and understanding recent discoveries

    (Advances in experimental medicine and biology ; 1191)

    2020  

    Author's details Yong-Ku Kim editor
    Series title Advances in experimental medicine and biology ; 1191
    Collection
    Language English
    Size vii, 576 Seiten, Illustrationen
    Publisher Springer
    Publishing place Singapore
    Publishing country Singapore
    Document type Book
    HBZ-ID HT020374952
    ISBN 978-981-329-704-3 ; 9789813297050 ; 981-329-704-2 ; 9813297050
    Database Catalogue ZB MED Medicine, Health

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  4. Book ; Online ; E-Book: Treatment resistance in psychiatry

    Kim, Yong-Ku

    risk factors, biology, and management

    2019  

    Author's details Yong-Ku Kim editor
    Keywords Psychiatry
    Subject code 616.89
    Language English
    Size 1 Online-Ressource (xv, 416 Seiten)
    Publisher Springer
    Publishing place Singapore
    Publishing country Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019958832
    ISBN 978-981-10-4358-1 ; 9789811043574 ; 981-10-4358-2 ; 9811043574
    DOI 10.1007/978-981-10-4358-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Book: Frontiers in psychiatry

    Kim, Yong-Ku

    artificial intelligence, precision medicine, and other paradigm shifts

    (Advances in experimental medicine and biology ; 1192)

    2019  

    Author's details Yong-Ku Kim editor
    Series title Advances in experimental medicine and biology ; 1192
    Collection
    Language English
    Size xi, 641 Seiten, Illustrationen
    Publisher Springer
    Publishing place Singapore
    Publishing country Singapore
    Document type Book
    HBZ-ID HT020307020
    ISBN 978-981-32-9720-3 ; 9789813297210 ; 981-32-9720-4 ; 9813297212
    Database Catalogue ZB MED Medicine, Health

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  6. Book ; Online: Major Depressive Disorder : Cognitive and Neurobiological Mechanisms

    Kim, Yong-Ku

    2015  

    Keywords Neurosciences
    Size 1 electronic resource (156 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021046461
    ISBN 9789535172406 ; 9535172409
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  7. Article ; Online: Recent advances and challenges in major depressive disorder.

    Kim, Yong-Ku

    Progress in neuro-psychopharmacology & biological psychiatry

    2021  Volume 111, Page(s) 110403

    MeSH term(s) Antidepressive Agents/therapeutic use ; Bipolar Disorder/drug therapy ; Depressive Disorder, Major/drug therapy ; Humans
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2021-07-20
    Publishing country England
    Document type Editorial
    ZDB-ID 781181-0
    ISSN 1878-4216 ; 0278-5846
    ISSN (online) 1878-4216
    ISSN 0278-5846
    DOI 10.1016/j.pnpbp.2021.110403
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Molecular Imaging of Neuroinflammation in Alzheimer's Disease and Mild Cognitive Impairment.

    Kim, Junhyung / Kim, Yong-Ku

    Advances in experimental medicine and biology

    2023  Volume 1411, Page(s) 301–326

    Abstract: Alzheimer's disease (AD) is the most prevalent neurocognitive disorder. Due to the ineffectiveness of treatments targeting the amyloid cascade, molecular biomarkers for neuroinflammation are attracting attention with increasing knowledge about the role ... ...

    Abstract Alzheimer's disease (AD) is the most prevalent neurocognitive disorder. Due to the ineffectiveness of treatments targeting the amyloid cascade, molecular biomarkers for neuroinflammation are attracting attention with increasing knowledge about the role of neuroinflammation in the pathogenesis of AD. This chapter will explore the results of studies using molecular imaging for diagnosing AD and mild cognitive impairment (MCI). Because it is critical to interpreting the data to understand which substances are targeted in molecular imaging, this chapter will discuss the two most significant targets, microglia and astrocytes, as well as the best-known radioligands for each. Then, neuroimaging results with PET neuroinflammation imaging will be reviewed for AD and MCI. Although a growing body of evidence has suggested that these molecular imaging biomarkers for neuroinflammation may have a role in the diagnosis of AD and MCI, the findings are inconsistent or cross-sectional, which indicates that it is difficult to apply the contents in practice due to the need for additional study. In particular, because the results of multiple interventions targeting neuroinflammation were inconclusive, molecular imaging markers for neuroinflammation can be used in combination with conventional markers to select appropriate patients for early intervention for neuroinflammation rather than as a single marker.
    MeSH term(s) Humans ; Alzheimer Disease/pathology ; Neuroinflammatory Diseases ; Cross-Sectional Studies ; Cognitive Dysfunction/diagnostic imaging ; Molecular Imaging ; Biomarkers
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-03-22
    Publishing country United States
    Document type Journal Article
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-981-19-7376-5_14
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Major Depressive Disorder: Current Advances and Paradigm Shifts.

    Kim, Yong-Ku

    Psychiatry investigation

    2020  Volume 17, Issue 3, Page(s) 179–180

    Language English
    Publishing date 2020-03-23
    Publishing country Korea (South)
    Document type Editorial
    ZDB-ID 2414364-9
    ISSN 1976-3026 ; 1738-3684
    ISSN (online) 1976-3026
    ISSN 1738-3684
    DOI 10.30773/pi.2019.0092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Microbiota-Gut-Brain Axis: Pathophysiological Mechanism in Neuropsychiatric Disorders.

    Shin, Cheolmin / Kim, Yong-Ku

    Advances in experimental medicine and biology

    2023  Volume 1411, Page(s) 17–37

    Abstract: Gut microbiota influence human behavior. The immunological, metabolic, and endocrine systems are involved in bidirectional communication between the gut and the brain, which is regulated by microbes through the microbiota-derived neurochemicals and ... ...

    Abstract Gut microbiota influence human behavior. The immunological, metabolic, and endocrine systems are involved in bidirectional communication between the gut and the brain, which is regulated by microbes through the microbiota-derived neurochemicals and metabolites. Gut microbiota have certain effects on neurodevelopment and maturation of immunity. However, gut dysbiosis can lead to neuropsychiatric disorders. Animal research and clinical case-control studies have demonstrated that gut dysbiosis has an adverse effect on human behavior through a variety of mechanisms. Recent meta-analysis on clinical studies confirmed gut dysbiosis in several major neuropsychiatric disorders. Microbiota-targeted intervention has recently been in the spotlight and meta-analyses have confirmed its effectiveness. In this chapter, we summarize the evidence for the interactions between microbiota and brain-gut network, as well as the potential pathophysiological mechanisms involved.
    MeSH term(s) Animals ; Humans ; Brain-Gut Axis ; Dysbiosis ; Brain/metabolism ; Gastrointestinal Microbiome/physiology ; Microbiota ; Probiotics
    Language English
    Publishing date 2023-03-22
    Publishing country United States
    Document type Journal Article
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-981-19-7376-5_2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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