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  1. Book ; Online ; Thesis: Untersuchungen zur Bildung von Tight Junctions in der humanen Colon-Adenocarcinom-Zellinie HT29

    Faff, Ortwin Michael [Verfasser] / Bacher, A. [Akademischer Betreuer] / Honegger, H.-W. [Gutachter] / Bacher, A. [Gutachter]

    2024  

    Author's details Ortwin Michael Faff ; Gutachter: H.-W. Honegger, A. Bacher ; Betreuer: A. Bacher
    Keywords Pflanzen (Botanik) ; Plants (Botany)
    Subject code sg580
    Language German
    Publisher Universitätsbibliothek der TU München
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  2. Article ; Online: Fusarium sporotrichioides

    Svoboda, Thomas / Labuda, Roman / Sulyok, Michael / Krska, Rudolf / Bacher, Markus / Berthiller, Franz / Adam, Gerhard

    Toxins

    2024  Volume 16, Issue 2

    Abstract: ... ...

    Abstract Fusarium
    MeSH term(s) Humans ; Glucosides/metabolism ; Fusarium/metabolism ; Oryza/metabolism ; T-2 Toxin/analogs & derivatives ; Mycotoxins/metabolism
    Chemical Substances Glucosides ; HT-2 toxin (NC6C26RM46) ; T-2 Toxin (I3FL5NM3MO) ; Mycotoxins
    Language English
    Publishing date 2024-02-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518395-3
    ISSN 2072-6651 ; 2072-6651
    ISSN (online) 2072-6651
    ISSN 2072-6651
    DOI 10.3390/toxins16020099
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Clinical Impact of Single Nucleotide Polymorphism in CD-19 on Treatment Outcome in FMC63-CAR-T Cell Therapy.

    Seipel, Katja / Abbühl, Mariesol / Bacher, Ulrike / Nilius, Henning / Daskalakis, Michael / Pabst, Thomas

    Cancers

    2023  Volume 15, Issue 11

    Abstract: Chimeric antigen receptor (CAR)-T cell therapy is effective in patients with relapsed or refractory diffuse large B-cell lymphoma (r/r DLBCL) with response rates of 63-84% and complete response observed in 43-54%. Common germline variants of the target ... ...

    Abstract Chimeric antigen receptor (CAR)-T cell therapy is effective in patients with relapsed or refractory diffuse large B-cell lymphoma (r/r DLBCL) with response rates of 63-84% and complete response observed in 43-54%. Common germline variants of the target antigen CD19 may elicit different responses to CAR-T cell therapy. The CD19 gene single nucleotide polymorphism rs2904880 encoding leucine or valine at amino acid position 174 of the CD19 antigen was prevalent in 51% of the studied DLBCL patients. In a retrospective comparative analysis of clinical outcome, there were significant differences in CD19 L174 versus V174 carriers: the median time of progression-free survival was 22 vs. 6 months (
    Language English
    Publishing date 2023-06-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15113058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Efficacy and Safety of High-Dose Chemotherapy with Treosulfan and Melphalan in Multiple Myeloma.

    Gillich, Cédric / Akhoundova, Dilara / Hayoz, Michael / Aebi, Yolanda / Largiadèr, Carlo R / Seipel, Katja / Daskalakis, Michael / Bacher, Ulrike / Pabst, Thomas

    Cancers

    2023  Volume 15, Issue 10

    Abstract: 1) Background: Upfront treatment consolidation with high-dose chemotherapy (HDCT) and autologous stem cell transplantation (ASCT) has relevantly contributed to achieving durable remissions following induction treatment in multiple myeloma (MM) patients. ...

    Abstract (1) Background: Upfront treatment consolidation with high-dose chemotherapy (HDCT) and autologous stem cell transplantation (ASCT) has relevantly contributed to achieving durable remissions following induction treatment in multiple myeloma (MM) patients. The optimization of HDCT regimens can, therefore, essentially contribute to improving the depth and duration of tumor remissions. To date, melphalan at 200 mg/m
    Language English
    Publishing date 2023-05-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15102699
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Thesis: Der unzufriedene Patient

    Bacher, Michael

    1987  

    Author's details vorgelegt von Michael Bacher
    Size 2 Mikrofiches : 24x
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Münster, Westf., Univ., Diss., 1987 (Nur als Mikrofiche f.d. Austausch)
    Note Mikroreprod. e. Ms. 146 Bl.: graph. Darst.
    HBZ-ID HT003021014
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1987 MB 170 order for loan Magazin

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  6. Article ; Online: Despite Good Correlations, There Is No Exact Coincidence between Isometric and Dynamic Strength Measurements in Elite Youth Soccer Players.

    Wagner, Carl-M / Warneke, Konstantin / Bächer, Christoph / Liefke, Christian / Paintner, Philipp / Kuhn, Larissa / Brauner, Torsten / Wirth, Klaus / Keiner, Michael

    Sports (Basel, Switzerland)

    2022  Volume 10, Issue 11

    Abstract: Speed strength performances are substantially dependent on maximum strength. Due to their importance, various methods have been utilized to measure maximum strength (e.g., isometric or dynamic) with discussed differences regarding transferability to ... ...

    Abstract Speed strength performances are substantially dependent on maximum strength. Due to their importance, various methods have been utilized to measure maximum strength (e.g., isometric or dynamic) with discussed differences regarding transferability to sport-specific movements dependent upon the testing procedure. The aim of this study was to analyze whether maximum isometric force (MIF) during isometric back squats correlates with maximum strength measurements of the one repetition maximum (1RM) in the squat, with countermovement jump (CMJ) performance, and with drop jump (DJ) performances in elite youth soccer players (
    Language English
    Publishing date 2022-11-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704239-X
    ISSN 2075-4663 ; 2075-4663
    ISSN (online) 2075-4663
    ISSN 2075-4663
    DOI 10.3390/sports10110175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Perioperatives Ernährungsmanagement

    Schemmer, Peter / Mischinger, Hans-Jörg / Lemmerer, Martina / Eisenberger, Anna Maria / Berger, Stefanie / Kornprat, Peter / Pfeifer, Johann / Kugel, Eva / Prisching, Anna / Fink, Nadja / Fuchs, Anita / Henneth, Barbara / Liendl, Franz / Uranüs, Selman / Auer, Thomas / Thalhammer, Michael / Bacher, Heinz / Gincu, Vasile / El-Shabrawi, Azab Mohamed /
    Müller, Helmut / Werkgartner, Georg

    How we do it

    2020  

    Institution LKH-Univ. Klinikum Graz
    Author's details LKH-Univ. Klinikum Graz, Fachbereich für Allgemein-, Viszeral- und Transplantationchirurgie und Ernährungsmedizinischer Dienst ; Peter Schemmer, Hans-Jörg Mischinger, Martina Lemmerer, Anna Maria Eisenberger [und weitere]
    Keywords klinische Ernährung ; nutrition support ; Ernährung ; Perioperatives Ernährungsmanagement ; Chirurgie ; perioperativ
    Subject code 610
    Language German
    Size 45 Seiten, 1 Illustration, 29.7 cm x 21 cm, 280 g
    Edition 1. Auflage
    Publisher Ernährungsmed. Dienst LKH-Univ. Klinikum
    Publishing place Graz
    Publishing country Austria
    Document type Book
    HBZ-ID HT020546276
    ISBN 978-3-200-06752-3 ; 3-200-06752-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2020 A 1140 available for loan (reading room) Lesesaal EG

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  8. Article ; Online: Regulation of Transcription Factor NF-κB in Its Natural Habitat: The Nucleus.

    Bacher, Susanne / Meier-Soelch, Johanna / Kracht, Michael / Schmitz, M Lienhard

    Cells

    2021  Volume 10, Issue 4

    Abstract: Activation of the transcription factor NF-κB elicits an individually tailored transcriptional response in order to meet the particular requirements of specific cell types, tissues, or organs. Control of the induction kinetics, amplitude, and termination ... ...

    Abstract Activation of the transcription factor NF-κB elicits an individually tailored transcriptional response in order to meet the particular requirements of specific cell types, tissues, or organs. Control of the induction kinetics, amplitude, and termination of gene expression involves multiple layers of NF-κB regulation in the nucleus. Here we discuss some recent advances in our understanding of the mutual relations between NF-κB and chromatin regulators also in the context of different levels of genome organization. Changes in the 3D folding of the genome, as they occur during senescence or in cancer cells, can causally contribute to sustained increases in NF-κB activity. We also highlight the participation of NF-κB in the formation of hierarchically organized super enhancers, which enable the coordinated expression of co-regulated sets of NF-κB target genes. The identification of mechanisms allowing the specific regulation of NF-κB target gene clusters could potentially enable targeted therapeutic interventions, allowing selective interference with subsets of the NF-κB response without a complete inactivation of this key signaling system.
    MeSH term(s) Animals ; Cell Nucleus/metabolism ; Chromatin Assembly and Disassembly ; Cytosol/metabolism ; Genome ; Humans ; NF-kappa B/metabolism ; Signal Transduction
    Chemical Substances NF-kappa B
    Language English
    Publishing date 2021-03-29
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells10040753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online ; Thesis: Massenspektrometrische Methoden in der Laboratoriumsmedizin

    Bächer, Silvia / Vogeser, Michael

    2014  

    Author's details Silvia Bächer. Betreuer: Michael Vogeser
    Language German
    Size Online-Ressource
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis München, Ludwig-Maximilians-Universität, Diss., 2014
    Database Former special subject collection: coastal and deep sea fishing

    Full text online

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  10. Article ; Online: CAR-T Cell Therapy Shows Similar Efficacy and Toxicity in Patients With DLBCL Regardless of CNS Involvement.

    Shumilov, Evgenii / Boyadzhiev, Hristo / Mazzeo, Paolo / Akhoundova, Dilara / Daskalakis, Michael / Novak, Urban / Lenz, Georg / Bacher, Ulrike / Pabst, Thomas

    HemaSphere

    2023  Volume 7, Issue 12, Page(s) e984

    Abstract: Efficacy and toxicity of chimeric antigen receptor T (CAR-T) cell therapy in relapsed/refractory (r/r) diffuse large B-cell lymphoma (DLBCL) with central nervous system (CNS) involvement remain understudied. Here we analyzed the outcomes of CAR-T cell ... ...

    Abstract Efficacy and toxicity of chimeric antigen receptor T (CAR-T) cell therapy in relapsed/refractory (r/r) diffuse large B-cell lymphoma (DLBCL) with central nervous system (CNS) involvement remain understudied. Here we analyzed the outcomes of CAR-T cell therapy in r/r DLBCL patients with CNS involvement and compared them with patients without CNS disease. Retrospective and monocentric comparative analysis of patient cohort with r/r DLBCL treated with CAR-T cell therapy: 15 patients with CNS versus 65 patients without CNS involvement. Overall response rates (80% versus 80%;
    Language English
    Publishing date 2023-11-30
    Publishing country United States
    Document type Journal Article
    ISSN 2572-9241
    ISSN (online) 2572-9241
    DOI 10.1097/HS9.0000000000000984
    Database MEDical Literature Analysis and Retrieval System OnLINE

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