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  1. Article: Brucellar Endocarditis of the Tricuspid Valve: A Case Report and Review of the Literature.

    Boumis, Evangelo / Chinello, Pierangelo / Galati, Vincenzo / Topino, Simone / Gavaruzzi, Francesca / Cicalini, Stefania

    Pathogens (Basel, Switzerland)

    2024  Volume 13, Issue 3

    Abstract: Brucellar endocarditis is a rare entity commonly described as a severe disease associated with high mortality and generally requiring valve surgery for cure. Right-sided endocarditis, a very uncommon presentation of brucellosis, may be associated with a ... ...

    Abstract Brucellar endocarditis is a rare entity commonly described as a severe disease associated with high mortality and generally requiring valve surgery for cure. Right-sided endocarditis, a very uncommon presentation of brucellosis, may be associated with a better prognosis. We describe the case of a 72-year-old woman admitted to our institution with a persistent fever and multiple pulmonary infiltrates. Transthoracic echocardiography and serologic tests led to the diagnosis of brucellar tricuspid endocarditis. The patient responded favorably to antibiotic treatment alone and did not need surgery. Prolonged antibiotic therapy with a combination of drugs active on intracellular microorganisms in the absence of surgical treatment could be effective in brucellar tricuspid endocarditis when the valve is not severely damaged.
    Language English
    Publishing date 2024-03-08
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens13030239
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Giant cell arteritis after COVID-19 vaccination/disease: suggestions for further shots?

    Chinello, Pierangelo / Gavaruzzi, Francesca / Epifani, Anna Chiara / Taglietti, Fabrizio

    Vascular

    2022  , Page(s) 17085381221140161

    Language English
    Publishing date 2022-11-17
    Publishing country England
    Document type Letter
    ZDB-ID 2137151-9
    ISSN 1708-539X ; 1708-5381
    ISSN (online) 1708-539X
    ISSN 1708-5381
    DOI 10.1177/17085381221140161
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4277: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  3. Article: Streptococcus intermedius

    Gavaruzzi, Francesca / Chinello, Pierangelo / Cucinotta, Giuseppe / Oliva, Gianluigi / Capone, Alessandro / Granata, Guido / Al Moghazi, Samir / Caraffa, Emanuela / Taglietti, Fabrizio

    Infectious disease reports

    2023  Volume 15, Issue 4, Page(s) 445–453

    Abstract: Streptococcus ... ...

    Abstract Streptococcus intermedius
    Language English
    Publishing date 2023-08-11
    Publishing country Switzerland
    Document type Case Reports
    ISSN 2036-7430
    ISSN 2036-7430
    DOI 10.3390/idr15040045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pharmacological treatment of HIV-associated pulmonary hypertension.

    Chinello, Pierangelo / Petrosillo, Nicola

    Expert review of clinical pharmacology

    2016  Volume 9, Issue 5, Page(s) 715–725

    Abstract: Pulmonary arterial hypertension (PAH) is a rare but severe disease that results from chronic obstruction of small pulmonary arteries, leading to right ventricular failure and, ultimately, death. One established risk factor for the development of PAH is ... ...

    Abstract Pulmonary arterial hypertension (PAH) is a rare but severe disease that results from chronic obstruction of small pulmonary arteries, leading to right ventricular failure and, ultimately, death. One established risk factor for the development of PAH is HIV infection. The presence of PAH is an independent risk factor for mortality in HIV-infected patients. This article will focus on HIV-associated PAH (HIV-PAH) with special considerations to the available treatments. With the approval of the soluble guanylate cyclase stimulator riociguat, a new drug class has become available in addition to the already existing prostanoids, endothelin receptor antagonists, and phosphodiesterase type 5 inhibitors. Guidelines for the treatment of idiopathic PAH and guidelines for antiretroviral therapy should be followed for the treatment of HIV-PAH.
    MeSH term(s) Anti-Retroviral Agents/administration & dosage ; Anti-Retroviral Agents/therapeutic use ; Antihypertensive Agents/administration & dosage ; Antihypertensive Agents/classification ; Antihypertensive Agents/pharmacology ; HIV Infections/complications ; HIV Infections/drug therapy ; Humans ; Hypertension, Pulmonary/drug therapy ; Hypertension, Pulmonary/pathology
    Chemical Substances Anti-Retroviral Agents ; Antihypertensive Agents
    Language English
    Publishing date 2016
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ISSN 1751-2441
    ISSN (online) 1751-2441
    DOI 10.1586/17512433.2016.1151785
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: What is the impact of post-COVID-19 syndrome on health-related quality of life and associated factors: a cross-sectional analysis.

    Mastrorosa, Ilaria / Del Duca, Giulia / Pinnetti, Carmela / Lorenzini, Patrizia / Vergori, Alessandra / Brita, Anna Clelia / Camici, Marta / Mazzotta, Valentina / Baldini, Francesco / Chinello, Pierangelo / Mencarini, Paola / Giancola, Maria Letizia / Abdeddaim, Amina / Girardi, Enrico / Vaia, Francesco / Antinori, Andrea

    Health and quality of life outcomes

    2023  Volume 21, Issue 1, Page(s) 28

    Abstract: Background: After the acute phase, symptoms or sequelae related to post-COVID-19 syndrome may persist for months. In a population of patients, previously hospitalized and not, followed up to 12 months after the acute infection, we aim to assess whether ... ...

    Abstract Background: After the acute phase, symptoms or sequelae related to post-COVID-19 syndrome may persist for months. In a population of patients, previously hospitalized and not, followed up to 12 months after the acute infection, we aim to assess whether and to what extent post-COVID-19 syndrome may have an impact on health-related quality of life (HRQoL) and to investigate influencing factors.
    Methods: We present the cross-sectional analysis of a prospective study, including patients referred to the post-COVID-19 service. Questionnaires and scales administered at 3, 6, 12 months were: Short-Form 36-item questionnaire (SF-36); Visual Analogue Scale of the EQ5D (EQ-VAS); in a subgroup, Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI-II) and Pittsburgh Sleep Quality Index (PSQI). Linear regression models were fitted to identify factors associated with HRQoL.
    Results: We considered the first assessment of each participant (n = 572). The mean scores in SF-36 and in EQ-VAS were significantly lower than the Italian normative values and remained stable over time, except the mental components score (MCS) of the SF-36 and EQ-VAS which resulted in lower ratings at the last observations. Female gender, presence of comorbidities, and corticosteroids treatment during acute COVID-19, were associated with lower scores in SF-36 and EQ-VAS; patients previously hospitalized (54%) reported higher MCS. Alterations in BAI, BDI-II, and PSQI (n = 265)were associated with lower ratings in SF-36 and EQ-VAS.
    Conclusions: This study provides evidence of a significantly bad perception of health status among persons with post-COVID-19 syndrome, associated with female gender and, indirectly, with disease severity. In case of anxious-depressive symptoms and sleep disorders, a worse HRQoL was also reported. A systematic monitoring of these aspects is recommended to properly manage the post-COVID-19 period.
    MeSH term(s) Humans ; Female ; Quality of Life ; Cross-Sectional Studies ; Post-Acute COVID-19 Syndrome ; Prospective Studies ; COVID-19 ; Surveys and Questionnaires
    Language English
    Publishing date 2023-03-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2098765-1
    ISSN 1477-7525 ; 1477-7525
    ISSN (online) 1477-7525
    ISSN 1477-7525
    DOI 10.1186/s12955-023-02107-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Salmonella

    Chinello, Pierangelo / Granata, Guido / Galati, Vincenzo / Taglietti, Fabrizio / Topino, Simone / Caraffa, Emanuela / Venditti, Carolina / Bevilacqua, Nazario / Sbardella, Lucilla / Bilei, Stefano / Petrosillo, Nicola

    Pathogens (Basel, Switzerland)

    2020  Volume 9, Issue 8

    Abstract: Salmonella ... ...

    Abstract Salmonella enterica
    Language English
    Publishing date 2020-08-15
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens9080656
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: QTc interval prolongation during favipiravir therapy in an Ebolavirus-infected patient.

    Chinello, Pierangelo / Petrosillo, Nicola / Pittalis, Silvia / Biava, Gianluigi / Ippolito, Giuseppe / Nicastri, Emanuele

    PLoS neglected tropical diseases

    2017  Volume 11, Issue 12, Page(s) e0006034

    MeSH term(s) Adult ; Amides/adverse effects ; Amides/therapeutic use ; Antiviral Agents/adverse effects ; Antiviral Agents/therapeutic use ; Arrhythmias, Cardiac/chemically induced ; Ebolavirus/drug effects ; Ebolavirus/pathogenicity ; Electrocardiography ; Hemorrhagic Fever, Ebola/drug therapy ; Hemorrhagic Fever, Ebola/virology ; Humans ; Italy ; Levofloxacin/adverse effects ; Levofloxacin/therapeutic use ; Male ; Pyrazines/adverse effects ; Pyrazines/therapeutic use ; RNA Replicase/antagonists & inhibitors ; Virus Replication/drug effects
    Chemical Substances Amides ; Antiviral Agents ; Pyrazines ; Levofloxacin (6GNT3Y5LMF) ; RNA Replicase (EC 2.7.7.48) ; favipiravir (EW5GL2X7E0)
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2429704-5
    ISSN 1935-2735 ; 1935-2727
    ISSN (online) 1935-2735
    ISSN 1935-2727
    DOI 10.1371/journal.pntd.0006034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Salmonella Hessarek Gastroenteritis with Bacteremia: A Case Report and Literature Review

    Chinello, Pierangelo / Granata, Guido / Galati, Vincenzo / Taglietti, Fabrizio / Topino, Simone / Caraffa, Emanuela / Venditti, Carolina / Bevilacqua, Nazario / Sbardella, Lucilla / Bilei, Stefano / Petrosillo, Nicola

    Pathogens. 2020 Aug. 15, v. 9, no. 8

    2020  

    Abstract: Salmonella enterica subspecies enterica serotype Hessarek (Salmonella Hessarek) is considered a serovar with high host specificity and is an uncommon cause of disease in humans; no cases of S. Hessarek bacteremia have been reported in humans to date. On ... ...

    Abstract Salmonella enterica subspecies enterica serotype Hessarek (Salmonella Hessarek) is considered a serovar with high host specificity and is an uncommon cause of disease in humans; no cases of S. Hessarek bacteremia have been reported in humans to date. On 16 July 2019, a young male presented abdominal pain, vomit, diarrhea, and fever up to 41 °C, a few hours after a kebab meal containing goat meat; he went to the Emergency Room, where a Film Array® GI Panel (BioFire, Biomerieux Company, Marcy-L´Étoile, France) was performed on his feces and results were positive for Salmonella. The culture of the feces was negative, but the blood culture was positive for Salmonella spp., which was identified as Salmonella Hessarek by seroagglutination assays. The patient was treated with ceftriaxone 2 g intravenously qd for 8 days; he was discharged in good general conditions, and ciprofloxacin 500 mg per os bid for 7 more days was prescribed, after exclusion of endocarditis and of clinical signs of complicated bacteremia. This case of Salmonella Hessarek gastroenteritis with bacteremia is probably the first case of bloodstream human infection due to this agent ever described. Further studies are needed to ascertain the global burden of S. Hessarek disease in humans.
    Keywords Salmonella ; assays ; bacteremia ; blood ; blood flow ; case studies ; ceftriaxone ; ciprofloxacin ; diarrhea ; endocarditis ; feces ; fever ; gastroenteritis ; goat meat ; host specificity ; human diseases ; humans ; intravenous injection ; literature ; males ; pain ; pathogens ; patients ; serotypes ; France
    Language English
    Dates of publication 2020-0815
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    Note NAL-light
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens9080656
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Disinfection of personal protective equipment for management of Ebola patients.

    Puro, Vincenzo / Pittalis, Silvia / Chinello, Pierangelo / Nicastri, Emanuele / Petrosillo, Nicola / Antonini, Mario / Ippolito, Giuseppe

    American journal of infection control

    2015  Volume 43, Issue 12, Page(s) 1375–1376

    MeSH term(s) Disinfection/standards ; Equipment Reuse/standards ; Health Personnel ; Humans ; Ventilators, Mechanical/standards
    Language English
    Publishing date 2015-12-01
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2015.07.040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1773: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  10. Article ; Online: QT interval prolongation and antiretroviral treatment: another point of interest.

    Chinello, Pierangelo / Petrosillo, Nicola

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2007  Volume 44, Issue 10, Page(s) 1388–9; author reply 1389–91

    MeSH term(s) Anti-Retroviral Agents/adverse effects ; HIV ; HIV Infections/complications ; HIV Infections/drug therapy ; Humans ; Long QT Syndrome/chemically induced ; Long QT Syndrome/etiology
    Chemical Substances Anti-Retroviral Agents
    Language English
    Publishing date 2007-05-15
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1086/516614
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    Zs.MO 480: Show issues

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