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  1. Article ; Online: A Systematic Literature Review on Pricing Strategies in the Sharing Economy

    Meijian Yang / Enjun Xia

    Sustainability, Vol 13, Iss 9762, p

    2021  Volume 9762

    Abstract: As an emerging business model, the sharing economy has gained a large amount of academic attention; the pricing problem in the sharing economy has also been widely investigated. Aiming to capture the current state-of-the-art research on pricing ... ...

    Abstract As an emerging business model, the sharing economy has gained a large amount of academic attention; the pricing problem in the sharing economy has also been widely investigated. Aiming to capture the current state-of-the-art research on pricing strategies in the sharing economy and foreseeing directions for future research, this article conducts a systematic literature review and content analysis of 158 articles from the Scopus and Web of Science databases. As a result, first, this review proposes an extended definition covering B2C and C2C models and a model structure covering the entire supply chain, based on which 158 articles are categorized into nine sub-models covering 30 scenarios. Second, the general characteristics (i.e., research fields, time and journal distributions, research themes and scenarios) and technical details (i.e., theories, methodologies, approaches, models, and conclusions) of the 158 articles are reviewed and summarized by the pricing party, business mode, and scenario. Finally, this review proposes some future research directions of existing scenarios from the perspectives of information asymmetry, market competition, and empirical approaches, and discusses some extensions, including uninvestigated scenarios and COVID-19-related topics; correspondingly, this review suggests some analytical models and empirical approaches that can be employed to fill these gaps. The proposed research directions and corresponding approaches can be references for future research.
    Keywords sharing economy ; price ; pricing ; systematic literature review ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 330
    Language English
    Publishing date 2021-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Wound microenvironment self-adaptive all-in-one hydrogel for rapid healing of the diabetic wound.

    Li, Jingjing / Gao, Xin / Li, Shaochun / Zhang, Xinyu / Guo, Jiamin / Wang, Bei / Jin, Yi / Zhang, Jinchao / Yang, Xinjian / Wang, Enjun

    Journal of materials chemistry. B

    2024  Volume 12, Issue 8, Page(s) 2070–2082

    Abstract: The natural healing of diabetic wounds is collectively impeded by multiple factors, including hyperglycemia, angiogenesis disorders, acute oxidative stress, and prolonged inflammation. Although considerable effort has been devoted to solving these ... ...

    Abstract The natural healing of diabetic wounds is collectively impeded by multiple factors, including hyperglycemia, angiogenesis disorders, acute oxidative stress, and prolonged inflammation. Although considerable effort has been devoted to solving these problems, the treatment of diabetic wounds remains a major clinical obstacle. In light of this, we developed an innovative wound microenvironment self-adaptive hydrogel to promote the healing of diabetic wounds. The hydrogel was constructed by the crosslinking of 3-aminobenzeneboronic acid (PBA)-modified gelatin (Gel) and polyvinyl alcohol (PVA) by borate ester bonds, which showed high responsiveness to glucose. Meanwhile, the liposomes that encapsulated metformin, L-arginine, and L(+)-ascorbic acid were incorporated into the hydrogel framework. The hydrogel@lipo composite demonstrated shape adaptability, glucose responsiveness, and all-in-one capability, thereby effectively improving the intricate microenvironment of diabetic wounds.
    MeSH term(s) Humans ; Hydrogels/pharmacology ; Arginine ; Ascorbic Acid ; Glucose ; Diabetes Mellitus
    Chemical Substances Hydrogels ; Arginine (94ZLA3W45F) ; Ascorbic Acid (PQ6CK8PD0R) ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2702241-9
    ISSN 2050-7518 ; 2050-750X
    ISSN (online) 2050-7518
    ISSN 2050-750X
    DOI 10.1039/d3tb02426a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Tree Species Classification Based on Self-Supervised Learning with Multisource Remote Sensing Images

    Xueliang Wang / Nan Yang / Enjun Liu / Wencheng Gu / Jinglin Zhang / Shuo Zhao / Guijiang Sun / Jian Wang

    Applied Sciences, Vol 13, Iss 1928, p

    2023  Volume 1928

    Abstract: In order to solve the problem of manual labeling in semi-supervised tree species classification, this paper proposes a pixel-level self-supervised learning model named M-SSL (multisource self-supervised learning), which takes the advantage of the ... ...

    Abstract In order to solve the problem of manual labeling in semi-supervised tree species classification, this paper proposes a pixel-level self-supervised learning model named M-SSL (multisource self-supervised learning), which takes the advantage of the information of plenty multisource remote sensing images and self-supervised learning methods. Based on hyperspectral images (HSI) and multispectral images (MSI), the features were extracted by combining generative learning methods with contrastive learning methods. Two kinds of multisource encoders named MAAE (multisource AAE encoder) and MVAE (multisource VAE encoder) were proposed, respectively, which set up pretext tasks to extract multisource features as data augmentation. Then the features were discriminated by the depth-wise cross attention module (DCAM) to enhance effective ones. At last, joint self-supervised methods output the tress species classification map to find the trade-off between providing negative samples and reducing the amount of computation. The M-SSL model can learn more representative features in downstream tasks. By employing the feature cross-fusion process, the low-dimensional information of the data is simultaneously learned in a unified network. Through the validation of three tree species datasets, the classification accuracy reached 78%. The proposed method can obtain high-quality features and is more suitable for label-less tree species classification.
    Keywords self-supervised learning ; tree species classification ; multisource remote sensing images ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 006
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Constructing Nitrogen-Doped Carbon Hierarchy Structure Derived from Metal-Organic Framework as High-Performance ORR Cathode Material for Zn-Air Battery.

    Pan, Yangdan / Gao, Junkuo / Li, Yuwen / Lv, Enjun / Khan, Usman / Yang, Xiaogang / Yao, Juming / Nairan, Adeela / Zhang, Qichun

    Small (Weinheim an der Bergstrasse, Germany)

    2023  Volume 20, Issue 3, Page(s) e2304594

    Abstract: The development of efficient and low-cost catalysts for cathodic oxygen reduction reaction (ORR) in Zn-air battery (ZAB) is a key factor in reducing costs and achieving industrialization. Here, a novel segregated CoNiPt alloy embedded in N-doped porous ... ...

    Abstract The development of efficient and low-cost catalysts for cathodic oxygen reduction reaction (ORR) in Zn-air battery (ZAB) is a key factor in reducing costs and achieving industrialization. Here, a novel segregated CoNiPt alloy embedded in N-doped porous carbon with a nanoflowers (NFs)-like hierarchy structure is synthesized through pyrolyzing Hofmann-type metal-organic frameworks (MOFs). The unique hierarchical NFs structure exposes more active sites and facilitates the transportation of reaction intermediates, thus accelerating the reaction kinetics. Impressively, the resulting 15% CoNiPt@C NFs catalyst exhibits outstanding alkaline ORR activity with a half-wave potential of 0.93 V, and its mass activity is 7.5 times higher than that of commercial Pt/C catalyst, surpassing state-of-the-art noble metal-based catalysts. Furthermore, the assembled CoNiPt@C+RuO2 ZAB demonstrates a maximum power density of 172 mW cm
    Language English
    Publishing date 2023-09-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2168935-0
    ISSN 1613-6829 ; 1613-6810
    ISSN (online) 1613-6829
    ISSN 1613-6810
    DOI 10.1002/smll.202304594
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: CircRbms1 fosters MST1 mRNA and protein levels to motivate myocardial ischaemia-reperfusion injury via autophagic status.

    Liu, Qin / Lai, Guorong / Hu, Yanhui / Yang, Fan / Zhang, Chao / Le, Dongsheng / Deng, Fumou / Xing, Xianliang / Tang, Binquan / Jie, Huanhuan / Liang, Yingping / Lei, Enjun

    ESC heart failure

    2024  Volume 11, Issue 2, Page(s) 1205–1217

    Abstract: Aims: Acute myocardial infarction (MI) is a significant contributor to death in individuals diagnosed with coronary heart disease on a worldwide level. The specific mechanism by which circRbms1 contributes to the damage caused by myocardial ischaemia- ... ...

    Abstract Aims: Acute myocardial infarction (MI) is a significant contributor to death in individuals diagnosed with coronary heart disease on a worldwide level. The specific mechanism by which circRbms1 contributes to the damage caused by myocardial ischaemia-reperfusion (I/R) is not well understood. The primary aim of this study was to examine the role of circRbms1 and its associated mechanisms in the setting of I/R injury.
    Methods and results: An in vivo MI mice model and an in vitro MI cell model was established. The expression levels were detected using quantitative real-time PCR (qRT-PCR) and western blot. Cellular proliferation, apoptosis, pyroptosis, and autophagy were detected by immunostaining, immunohistochemistry, western blot, and transmission electron microscopy (TEM). Dual-luciferase reporter assay, RNA pull-down assay, and RIP assay were performed to validate the molecular interactions. CircRbms1 was up-regulated in A/R-induced HCMs and acted as a sponge for miR-142-3p, thereby targeting MST1. CircRbms1 could improve stability of MST1 by recruiting IGF2BP2 (all P < 0.05). CircRbms1 knockout reduced cell pyroptosis, improved autophagy and proliferation level in A/R-induced HCMs (all P < 0.05). CircRbms1 knockout alleviated cardiac dysfunction and cell pyroptosis and enhanced autophagy and proliferation in mice through the miR-142-3p/MST1 axis.
    Conclusions: CircRbms1 inhibited the miR-142-3p/MST1 axis and played a protective role in myocardial I/R injury. It may provide a new therapeutic target for I/R heart injury.
    MeSH term(s) Animals ; Mice ; Autophagy/genetics ; MicroRNAs/genetics ; Myocardial Ischemia ; Myocardial Reperfusion Injury/genetics ; RNA, Messenger
    Chemical Substances MicroRNAs ; RNA, Messenger ; macrophage stimulating protein
    Language English
    Publishing date 2024-01-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2814355-3
    ISSN 2055-5822 ; 2055-5822
    ISSN (online) 2055-5822
    ISSN 2055-5822
    DOI 10.1002/ehf2.14673
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Long-term exposure to dietary emulsifier Tween 80 promotes liver lipid accumulation and induces different-grade inflammation in young and aged mice.

    Xie, Enjun / Chen, Yunmei / Yang, Wanbao / Pan, Quan / Zheng Shen, James / Zhou, Fenghua / Shen, Jie / Li, Tao / Li, Qili / Li, Xiaopeng

    Food research international (Ottawa, Ont.)

    2024  Volume 184, Page(s) 114205

    Abstract: With the advent of industrialization, there has been a substantial increase in the production and consumption of ultra-processed foods (UPFs). These processed foods often contain artificially synthesized additives, such as emulsifiers. Emulsifiers ... ...

    Abstract With the advent of industrialization, there has been a substantial increase in the production and consumption of ultra-processed foods (UPFs). These processed foods often contain artificially synthesized additives, such as emulsifiers. Emulsifiers constitute approximately half of the total amount of food additives, with Tween 80 being a commonly used emulsifier in the food industry. Concurrently, China is undergoing significant demographic changes, transitioning into an aging society. Despite this demographic shift, there is insufficient research on the health implications of food emulsifiers, particularly on the elderly population. In this study, we present novel findings indicating that even at low concentrations, Tween 80 suppressed the viability of multiple cell types. Prolonged in vivo exposure to 1 % Tween 80 in drinking water induced liver lipid accumulation and insulin resistance in young adult mice under a regular chow diet. Intriguingly, in mice with high-fat diet (HFD) induced metabolic dysfunction-associated steatotic liver disease (MASLD), this inductive effect was masked. In aged mice, liver lipid accumulation was replicated under prolonged Tween 80 exposure. We further revealed that Tween 80 induced inflammation in both adult and aged mice, with a more pronounced inflammation in aged mice. In conclusion, our study provides compelling evidence that Tween 80 could contribute to a low-grade inflammation and liver lipid accumulation. These findings underscore the need for increasing attention regarding the consumption of UPFs with Tween 80 as the emulsifier, particularly in the elderly consumers.
    MeSH term(s) Humans ; Aged ; Young Adult ; Animals ; Mice ; Polysorbates/adverse effects ; Diet, High-Fat ; Fatty Liver ; Emulsifying Agents/adverse effects ; Inflammation ; Lipids
    Chemical Substances Polysorbates ; Emulsifying Agents ; Lipids
    Language English
    Publishing date 2024-03-29
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1111695-x
    ISSN 1873-7145 ; 0963-9969
    ISSN (online) 1873-7145
    ISSN 0963-9969
    DOI 10.1016/j.foodres.2024.114205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Analytical and clinical evaluation of the light-initiated chemiluminescent assays for measurement of human thyroid hormones.

    Li, Jing / Huang, Youyuan / Xiang, Guiming / Xu, Enjun / Chen, Tao / Yang, Ming / Zhang, Jie

    Journal of clinical laboratory analysis

    2022  Volume 36, Issue 5, Page(s) e24266

    Abstract: Background: Light-initiated chemiluminescent assay (LiCA) is a new homogeneous immunoassay. The aim of this study was to evaluate the analytical and clinical performance of the assays for the detection of thyroid hormones based on the fully automated ... ...

    Abstract Background: Light-initiated chemiluminescent assay (LiCA) is a new homogeneous immunoassay. The aim of this study was to evaluate the analytical and clinical performance of the assays for the detection of thyroid hormones based on the fully automated LiCA 800 analyzer.
    Methods: Analytical validations of the LiCA thyroid assays (TSH, FT3, FT4, T3, and T4) included precision, linearity, analytical sensitivity, interference, and method comparison applying the protocols of the Clinical and Laboratory Standards Institute (CLSI). The diagnostic performance was assessed by the receiver operating characteristic (ROC) curve analysis with different assay schemes for the diagnosis of hyperthyroidism and hypothyroidism.
    Results: Within-run and within-lab precisions (%CV) of the five assays ranged from 1.06 to 6.40% at all concentrations evaluated. A satisfactory linearity was verified over the entire measuring range for TSH, T3, and T4 (R > 0.99, change in recovery <10%, p = 0.000 all). Paired-comparison measurements presented a comparable assay for each of the five assays (R > 0.96, median bias <5%, p < 0.0001 all) between LiCA and Cobas across three institutes. The diagnostic accuracy of the LiCA assays for hyperthyroidism or hypothyroidism was quantified by the areas under curves (AUC) as 0.925 or 0.832 with the five-assay panel (TSH, FT3, FT4, T3, and T4) and as 0.921 or 0.811 with the three-assay panel (TSH, FT3, and FT4), respectively. No significant difference was found between the AUC of LiCA and that of DxI, Cobas, or Centaur (p > 0.3 all).
    Conclusion: LiCA 800 provides a precise and high-throughput immunoassay platform for detection of thyroid hormones. It is acceptable for clinical use.
    MeSH term(s) Humans ; Hyperthyroidism/diagnosis ; Hypothyroidism/diagnosis ; Luminescent Measurements/methods ; Thyroid Hormones ; Thyrotropin ; Thyroxine ; Triiodothyronine
    Chemical Substances Thyroid Hormones ; Triiodothyronine (06LU7C9H1V) ; Thyrotropin (9002-71-5) ; Thyroxine (Q51BO43MG4)
    Language English
    Publishing date 2022-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645095-7
    ISSN 1098-2825 ; 0887-8013
    ISSN (online) 1098-2825
    ISSN 0887-8013
    DOI 10.1002/jcla.24266
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Thymic stromal lymphopoietin induces IL-4/IL-13 from T cells to promote sebum secretion and adipose loss.

    Choa, Ruth / Harris, Jordan C / Yang, EnJun / Yokoyama, Yuichi / Okumura, Mariko / Kim, MinJu / To, Jerrick / Lou, Meng / Nelson, Amanda / Kambayashi, Taku

    The Journal of allergy and clinical immunology

    2023  

    Abstract: Background: The cytokine TSLP promotes type 2 immune responses and can induce adipose loss by stimulating lipid loss from the skin through sebum secretion by sebaceous glands, which enhances the skin barrier. However, the mechanism by which TSLP ... ...

    Abstract Background: The cytokine TSLP promotes type 2 immune responses and can induce adipose loss by stimulating lipid loss from the skin through sebum secretion by sebaceous glands, which enhances the skin barrier. However, the mechanism by which TSLP upregulates sebaceous gland function is unknown.
    Objectives: This study investigated the mechanism by which TSLP stimulates sebum secretion and adipose loss.
    Methods: RNA-sequencing analysis was performed on sebaceous glands isolated by laser capture microdissection and single-cell RNA-sequencing analysis was performed on sorted skin T cells. Sebocyte function was analyzed by histological analysis and sebum secretion in vivo and by measuring lipogenesis and proliferation in vitro.
    Results: This study found that TSLP sequentially stimulated the expression of lipogenesis genes followed by cell death genes in sebaceous glands to induce holocrine secretion of sebum. TSLP did not affect sebaceous gland activity directly. Rather, single-cell RNA-sequencing revealed that TSLP recruited distinct T-cell clusters that produce IL-4 and IL-13, which were necessary for TSLP-induced adipose loss and sebum secretion. Moreover, IL-13 was sufficient to cause sebum secretion and adipose loss in vivo and to induce lipogenesis and proliferation of a human sebocyte cell line in vitro.
    Conclusions: This study proposes that TSLP stimulates T cells to deliver IL-4 and IL-13 to sebaceous glands, which enhances sebaceous gland function, turnover, and subsequent adipose loss.
    Language English
    Publishing date 2023-12-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2023.11.923
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Rewiring ERBB3 and ERK signaling confers resistance to FGFR1 inhibition in gastrointestinal cancer harbored an ERBB3-E928G mutation.

    Yang, Xiang / Wang, Hongxiao / Xie, Enjun / Tang, Biyao / Mu, Qingdian / Song, Zijun / Chen, Junyi / Wang, Fudi / Min, Junxia

    Protein & cell

    2020  Volume 11, Issue 12, Page(s) 915–920

    MeSH term(s) Amino Acid Substitution ; Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Drug Resistance, Neoplasm/drug effects ; Drug Resistance, Neoplasm/genetics ; Gastrointestinal Neoplasms/genetics ; Gastrointestinal Neoplasms/metabolism ; Gastrointestinal Neoplasms/pathology ; Humans ; MAP Kinase Signaling System/drug effects ; MAP Kinase Signaling System/genetics ; Mutation, Missense ; Receptor, ErbB-3/genetics ; Receptor, ErbB-3/metabolism ; Receptor, Fibroblast Growth Factor, Type 1/antagonists & inhibitors ; Receptor, Fibroblast Growth Factor, Type 1/genetics ; Receptor, Fibroblast Growth Factor, Type 1/metabolism
    Chemical Substances Antineoplastic Agents ; ERBB3 protein, human (EC 2.7.10.1) ; FGFR1 protein, human (EC 2.7.10.1) ; Receptor, ErbB-3 (EC 2.7.10.1) ; Receptor, Fibroblast Growth Factor, Type 1 (EC 2.7.10.1)
    Language English
    Publishing date 2020-07-06
    Publishing country Germany
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2543451-2
    ISSN 1674-8018 ; 1674-800X
    ISSN (online) 1674-8018
    ISSN 1674-800X
    DOI 10.1007/s13238-020-00749-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Isolation of Single Intracellular Bacterial Communities Generated from a Murine Model of Urinary Tract Infection for Downstream Single-cell Analysis.

    Yang, EnJun / Chee, Jacqueline L Y / Duraiswamy, Suhanya / Chen, Siyi / Lees, Kristin / Chen, Swaine L

    Journal of visualized experiments : JoVE

    2019  , Issue 146

    Abstract: In this article, we outline a procedure used to isolate individual intracellular bacterial communities from a mouse that has been experimentally infected in the urinary tract. The protocol can be broadly divided into three sections: the infection, ... ...

    Abstract In this article, we outline a procedure used to isolate individual intracellular bacterial communities from a mouse that has been experimentally infected in the urinary tract. The protocol can be broadly divided into three sections: the infection, bladder epithelial cell harvesting, and mouth micropipetting to isolate individual infected epithelial cells. The isolated epithelial cell contains viable bacterial cells and is nearly free of contaminating extracellular bacteria, making it ideal for downstream single-cell analysis. The time taken from the start of infection to obtaining a single intracellular bacterial community is about 8 h. This protocol is inexpensive to deploy and uses widely available materials, and we anticipate that it can also be utilized in other infection models to isolate single infected cells from cell mixtures even if those infected cells are rare. However, due to a potential risk in mouth micropipetting, this procedure is not recommended for highly infectious agents.
    MeSH term(s) Animals ; Bacteria/isolation & purification ; Disease Models, Animal ; Dissection ; Epithelial Cells/microbiology ; Mice ; Single-Cell Analysis ; Urinary Bladder/microbiology ; Urinary Bladder/pathology ; Urinary Tract Infections/microbiology
    Language English
    Publishing date 2019-04-16
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Video-Audio Media
    ZDB-ID 2259946-0
    ISSN 1940-087X ; 1940-087X
    ISSN (online) 1940-087X
    ISSN 1940-087X
    DOI 10.3791/58829
    Database MEDical Literature Analysis and Retrieval System OnLINE

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