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  1. Article ; Online: Unilateral Submandibular Gland Aplasia Mimicking Nodal Metastasis.

    Kandemirli, Sedat G

    Journal of pediatric hematology/oncology

    2019  Volume 42, Issue 3, Page(s) 220–221

    Abstract: Aplasia of salivary glands is rare and usually involves several major salivary glands. Isolated unilateral submandibular gland aplasia or aplasia accompanied by hypertrophy of contralateral submandibular gland or sublingual glands is a rare entity. The ... ...

    Abstract Aplasia of salivary glands is rare and usually involves several major salivary glands. Isolated unilateral submandibular gland aplasia or aplasia accompanied by hypertrophy of contralateral submandibular gland or sublingual glands is a rare entity. The majority of cases are incidentally detected findings in asymptomatic patients; however, imaging findings may mimic mass-like lesions, posing diagnostic challenges in cancer patients. We presented 2 cases, a case with melanoma and an asymptomatic case, who had asymmetric lesion at left submandibular space, demonstrated to represent left submandibular gland accompanied by right submandibular gland aplasia. We aimed to highlight the imaging features for correct identification of these mass-like lesions as normal contralateral salivary gland accompanied by unilateral submandibular gland aplasia.
    MeSH term(s) Diagnosis, Differential ; Humans ; Lymphatic Metastasis/diagnosis ; Submandibular Gland/abnormalities ; Submandibular Gland/pathology
    Language English
    Publishing date 2019-11-05
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1231152-2
    ISSN 1536-3678 ; 1077-4114 ; 0192-8562
    ISSN (online) 1536-3678
    ISSN 1077-4114 ; 0192-8562
    DOI 10.1097/MPH.0000000000001634
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Neuroimaging findings in rheumatologic disorders.

    Kandemirli, Sedat Giray / Bathla, Girish

    Journal of the neurological sciences

    2021  Volume 427, Page(s) 117531

    Abstract: Patients with rheumatological diseases may present with neurological manifestations of peripheral and/or central nervous system (CNS). Symptoms may be related to underlying rheumatological disease or CNS effects of immune-modulating drugs. Early ... ...

    Abstract Patients with rheumatological diseases may present with neurological manifestations of peripheral and/or central nervous system (CNS). Symptoms may be related to underlying rheumatological disease or CNS effects of immune-modulating drugs. Early diagnosis and therapy may help prevent serious complications. Magnetic resonance imaging (MRI), given its excellent soft tissue details, is the preferred imaging modality when evaluating patients with rheumatological disease and suspected CNS involvement. We present a review of the neuroimaging manifestations of various rheumatic diseases with emphasis on the imaging findings on MRI.
    MeSH term(s) Arthritis, Rheumatoid ; Central Nervous System ; Humans ; Magnetic Resonance Imaging ; Neuroimaging ; Rheumatic Diseases/complications ; Rheumatic Diseases/diagnostic imaging
    Language English
    Publishing date 2021-06-11
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 80160-4
    ISSN 1878-5883 ; 0022-510X ; 0374-8642
    ISSN (online) 1878-5883
    ISSN 0022-510X ; 0374-8642
    DOI 10.1016/j.jns.2021.117531
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Efficacy and Safety of Lumbar Accessed Catheter-Assisted Epidural Blood Patch in Cervical and Thoracic Cerebrospinal Fluid Leakage.

    Nas, Omer F / Oztepe, Muhammed F / Kandemirli, Sedat G / Demir, Aylin Bican / Bilgin, Cem / Inecikli, Mehmet F / Hakyemez, Bahattin

    World neurosurgery

    2022  Volume 168, Page(s) e233–e239

    Abstract: Objective: To evaluate the clinical and radiological results of lumbar accessed catheter-assisted epidural blood patch (LACA-EBP) technique in treatment of spontaneous intracranial hypotension secondary to cervicothoracic cerebrospinal fluid leakage.: ...

    Abstract Objective: To evaluate the clinical and radiological results of lumbar accessed catheter-assisted epidural blood patch (LACA-EBP) technique in treatment of spontaneous intracranial hypotension secondary to cervicothoracic cerebrospinal fluid leakage.
    Methods: Patients presenting with spontaneous intracranial hypotension where magnetic resonance imaging cisternography confirmed and localized the cerebrospinal fluid leakage at cervicothoracic levels were treated with LACA-EBP. Visual analog scale (VAS) score for headache at baseline, third day after treatment, and during long-term follow-up was used to assess the treatment response. Posttreatment VAS score ≤3 on the third day defined treatment success, and VAS score ≥4 indicated treatment failure.
    Results: LACA-EBP was performed in 10 patients (7 females, 3 males) with a mean age of 38.4 ± 10.5 years. Orthostatic headache was the most common presenting symptom (10/10; 100%) followed by nausea (5/10; 50%). Pituitary gland enlargement was the most commonly observed finding on pretreatment cranial magnetic resonance imaging (9/10; 90%). On magnetic resonance imaging cisternography, 8 patients had cervical and/or thoracic fistulas, whereas 2 patients had multiple-level fistulas. LACA-EBP was successful in all patients with no complications. All patients showed a treatment response with a 72-hour VAS score ≤3. Follow-up VAS scores were available for 8 patients with a clinical follow-up duration of 1-74 months (median 7.5 months). During clinical follow-up, headache recurred in 2 patients.
    Conclusions: In our study cohort, LACA-EBP was a safe and efficacious technique in treatment of cerebrospinal fluid leakage at cervical and thoracic levels.
    Language English
    Publishing date 2022-09-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2022.09.087
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  4. Article: Correlation of imaging and intraoperative findings in Pott's puffy tumour.

    Olmaz, Burak / Cingoz, Mehmet / Akdogan, Emin / Kandemirli, Sedat G

    Scottish medical journal

    2018  Volume 64, Issue 1, Page(s) 25–29

    Abstract: Introduction: Pott's puffy tumour is characterised by frontal bone osteomyelitis accompanied by subperiosteal abscess. It can be further complicated by intracranial extension of the infectious process.: Case presentation: A 12-year-old boy initially ... ...

    Abstract Introduction: Pott's puffy tumour is characterised by frontal bone osteomyelitis accompanied by subperiosteal abscess. It can be further complicated by intracranial extension of the infectious process.
    Case presentation: A 12-year-old boy initially presented with signs and imaging findings of pan-sinusitis. Despite antibiotic therapy, there was progressive swelling of the forehead region. Subsequent imaging studies revealed osteomyelitis of frontal bone, subcutaneous abscess and extension into intracranial space. The abscesses were surgically drained, and craniectomy for osteomyelitis was carried out.
    Conclusion: The initial symptoms of Pott's puffy tumour can be subtle, and antibiotic use may mask the underlying sinister involvement of intracranial structures. Imaging plays an important role both in diagnosis and detection of possible intracranial complications.
    MeSH term(s) Child ; Craniotomy/methods ; Humans ; Male ; Pott Puffy Tumor/diagnostic imaging ; Pott Puffy Tumor/pathology ; Pott Puffy Tumor/surgery ; Tomography, X-Ray Computed
    Language English
    Publishing date 2018-10-06
    Publishing country Scotland
    Document type Case Reports ; Journal Article
    ZDB-ID 414085-0
    ISSN 2045-6441 ; 0036-9330
    ISSN (online) 2045-6441
    ISSN 0036-9330
    DOI 10.1177/0036933018803787
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Imaging Features to Predict Response to Olfactory Training in Post-Traumatic Olfactory Dysfunction.

    Altundag, Aytug / Saatci, Ozlem / Kandemirli, Sedat G / Sanli, Deniz E T / Duz, Ozge A / Sanli, Ahmet N / Yildirim, Duzgun

    The Laryngoscope

    2021  Volume 131, Issue 7, Page(s) E2243–E2250

    Abstract: Objectives/hypothesis: Prognosis of post-traumatic olfactory dysfunction is poor, with medical treatment options showing limited success rates. Olfactory training (OT) has been introduced as a potential therapeutic option in olfactory dysfunction. We ... ...

    Abstract Objectives/hypothesis: Prognosis of post-traumatic olfactory dysfunction is poor, with medical treatment options showing limited success rates. Olfactory training (OT) has been introduced as a potential therapeutic option in olfactory dysfunction. We aimed to identify the imaging features that would predict a better response to OT and create an imaging-based prognostic scale.
    Methods: We retrospectively reviewed 52 patients that underwent OT at our center for post-traumatic olfactory dysfunction. Olfactory functions at the time of initial presentation and at completion of OT were evaluated using Sniffin' Sticks test and threshold discrimination identification (TDI) scores were calculated. Patients were divided into responders (ROT group: 16 cases) and non-responders (n-ROT group: 36 cases) to OT based on TDI score change (cut-off 5.5 point). Morphological measurements of olfactory fossa, olfactory bulb volume and signal abnormalities, olfactory nerve filia integrity, siderosis, encephalomalacic changes in olfactory cortex, and other cortical regions were reviewed.
    Results: There was no significant difference between the two groups in terms of age, gender distribution, olfactory dysfunction duration, head-trauma severity, and initial TDI scores. A model incorporating five variables: cribriform plate fracture, olfactory fossa depth (cut-off: 4.9 mm), olfactory bulb encephalomalacia, olfactory bulb volume (cut-off: 27.1 mm
    Conclusions: We developed an imaging-based scoring system with good specificity that can be used as an adjunctive tool for patient counseling, and optimal selection of management options.
    Level of evidence: 4 Laryngoscope, 131:E2243-E2250, 2021.
    MeSH term(s) Adult ; Aged ; Area Under Curve ; Craniocerebral Trauma/complications ; Female ; Humans ; Magnetic Resonance Imaging/methods ; Magnetic Resonance Imaging/statistics & numerical data ; Male ; Middle Aged ; Olfaction Disorders/diagnostic imaging ; Olfaction Disorders/etiology ; Olfaction Disorders/therapy ; Olfactory Bulb/diagnostic imaging ; Predictive Value of Tests ; Prognosis ; Reference Values ; Reproducibility of Results ; Retrospective Studies ; Sensitivity and Specificity ; Sensory Thresholds ; Signal Detection, Psychological ; Treatment Outcome ; Young Adult
    Language English
    Publishing date 2021-01-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.29392
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  6. Article ; Online: A technical note on intra-arterial cone-beam computed tomography for the evaluation of flow-diverter stents: Image quality differences between diluted and non-diluted contrast medium.

    Kocer, Naci / Kandemirli, Sedat G / Ruijters, Daniel / Mantatzis, Michalis / Kizilkilic, Osman / Islak, Civan

    Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences

    2019  Volume 26, Issue 2, Page(s) 164–169

    Abstract: Background: Design of flow-diverter stents for flexibility, tractability, and low profile limits their radiopacity on conventional digital subtraction angiography. Cone-beam computed tomography (CBCT) offers higher spatial resolution for the evaluation ... ...

    Abstract Background: Design of flow-diverter stents for flexibility, tractability, and low profile limits their radiopacity on conventional digital subtraction angiography. Cone-beam computed tomography (CBCT) offers higher spatial resolution for the evaluation of flow-diverter stents. However, CBCT requires optimal dilution and timing of contrast medium for simultaneous visualization of the stent, arterial lumen, and vessel wall. There are only limited data on the effects of different contrast dilutions on CBCT image quality in neurointerventional applications.
    Materials and methods: In our institution, intra-arterial CBCTs were acquired during stent deployment and at follow-ups with 10% diluted contrast. We had recently started acquiring intra-arterial CBCTs with non-diluted contrast. Retrospective analysis of our flow-diverter data identified eight cases with different aneurysm locations who had intra-arterial CBCT with 10% diluted contrast immediately after flow-diverter stent deployment and with non-diluted contrast technique during follow-ups. For each case, the image quality between diluted and non-diluted contrast techniques was compared qualitatively by assessing stent visualization and quantitatively by plotting gray-scale intensity values along the vessel lumen.
    Results: In two sets of CBCT images per each case, there was no substantial difference between diluted and non-diluted CBTC techniques for the evaluation of stent architecture and lumen opacification. Gray-scale intensity values perpendicular to the lumen revealed similar intensity values along the neighboring parenchyma, vessel wall, and lumen for the two different contrast techniques.
    Conclusion: Intra-arterial CBCT angiography can be performed without contrast dilution and still achieve adequate image quality in certain cerebral aneurysms treated with flow diverter. The non-diluted contrast technique avoids the time loss during preparation of diluted contrast and installation of diluted contrast to the injector in angiography suites with a single power injector.
    MeSH term(s) Angiography, Digital Subtraction ; Cerebral Angiography ; Cerebral Arteries/diagnostic imaging ; Cerebral Arteries/surgery ; Computed Tomography Angiography ; Cone-Beam Computed Tomography/methods ; Contrast Media ; Humans ; Image Processing, Computer-Assisted ; Retrospective Studies ; Stents ; Treatment Outcome
    Chemical Substances Contrast Media
    Language English
    Publishing date 2019-11-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1354913-3
    ISSN 2385-2011 ; 1591-0199 ; 1123-9344
    ISSN (online) 2385-2011
    ISSN 1591-0199 ; 1123-9344
    DOI 10.1177/1591019919890929
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  7. Article ; Online: Predictors of antegrade ureteral stenting failure: a single-center experience in patients with malignant and benign ureteral obstruction.

    Nas, Omer F / Oztepe, Muhammed F / Kandemirli, Sedat G / Bilgin, Cem / Ozkaya, Guven / Inecikli, Mehmet F / Kaygısız, Onur

    Abdominal radiology (New York)

    2020  Volume 46, Issue 5, Page(s) 2188–2194

    Abstract: Objective: To determine the potential predictors of antegrade ureteral stenting (AUS) failure in patients with malignant and benign ureteral obstruction.: Method: We retrospectively evaluated 116 AUS procedures performed in 80 patients for ureteral ... ...

    Abstract Objective: To determine the potential predictors of antegrade ureteral stenting (AUS) failure in patients with malignant and benign ureteral obstruction.
    Method: We retrospectively evaluated 116 AUS procedures performed in 80 patients for ureteral obstruction due to malignant and benign causes. Variables such as etiology for obstruction, ureter shape, previous treatment regimen, history of ileal loop diversion, and presence of percutaneous nephrostomy were recorded. Univariate and multivariate logistic regression methods were used between these variables and stent failure.
    Results: Antegrade ureteral stenting was performed as single stage in 24 procedures (n: 24/116, 21%) and performed as a two-step approach after percutaneous nephrostomy in 92 procedures (n: 92/116, 79%). Ureteral stent was successfully deployed in 112 AUS procedures (n: 112/116, 96.5%). In 35 of these successful procedures, the patients were referred to our department due to prior failed retrograde ureteral stenting (RUS). Subsequent stent failure occurred in 40 procedures after a median interval of 39 days. Pre-stenting percutaneous nephrostomy (PN) was a statistically significant risk factor for stent failure (p: 0.041), and age showed an inverse relationship with stent failure (p: 0.008). Complications in early (within the first 30 days after procedure) and late stage occurred in a total of 17 procedures. Early complications included urinary tract infection (n: 11), stent migration (n: 3), and malposition (n: 1). Late complications (after 30 days) were urinary tract infection (n: 1) and stent migration (n: 1).
    Conclusion: This study suggests that AUS can be performed effectively in both benign and malignant ureteral obstructions including cases with prior failed RUS. Two-step AUS after percutaneous nephrostomy was found to be a significant risk factor for subsequent stent failure in our study cohort.
    MeSH term(s) Humans ; Nephrostomy, Percutaneous ; Retrospective Studies ; Stents ; Ureter/diagnostic imaging ; Ureter/surgery ; Ureteral Obstruction/diagnostic imaging ; Ureteral Obstruction/surgery
    Language English
    Publishing date 2020-11-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2839786-1
    ISSN 2366-0058 ; 2366-004X
    ISSN (online) 2366-0058
    ISSN 2366-004X
    DOI 10.1007/s00261-020-02858-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Right- Versus Left-Sided Approach for Transhepatic Tunneled Catheter Placement: Is There a Difference?

    Nas, Omer F / Candan, Selman / Oztepe, Muhammed F / Kandemirli, Sedat G / Bilgin, Cem / Inecikli, Mehmet F / Ozkaya, Guven / Gokalp, Gokhan / Ongen, Gokhan / Erdogan, Cuneyt

    Cardiovascular and interventional radiology

    2021  Volume 44, Issue 7, Page(s) 1039–1047

    Abstract: Objective: We aimed to compare the technical difficulties, complications, long-term efficacy, and risks between right- and left-sided approach transhepatic tunneled catheterization.: Methods: We retrospectively evaluated transhepatic tunneled ... ...

    Abstract Objective: We aimed to compare the technical difficulties, complications, long-term efficacy, and risks between right- and left-sided approach transhepatic tunneled catheterization.
    Methods: We retrospectively evaluated transhepatic tunneled catheter placement cases in our institution between May 2012 and November 2019. Demographic and procedural parameters were recorded. Statistical tests were used to compare the complication rates of right- and left-sided approach. Furthermore, Cox regression analyses were used to investigate the relationship between functional catheter days and included parameters.
    Results: A total of 83 procedures were performed in 46 patients, with a female to male ratio of 1.88 and a mean age of 55.5 ± 18.2 years. Indication for catheter placement was chronic renal insufficiency and loss of central venous access through traditional routes in all cases. Median functional catheter durations were 28 days (1-382) and 55.5 days (1-780) for right-sided and left-sided access, respectively. Complication rates were similar for both sides. There was no difference between primary and revision procedures in terms of safety and efficacy outcomes. In univariate Cox regression analysis, gender was the only variable which was found to be statistically significant (HR = 2.014 (1.004-4.038)) for functional catheter days. In multivariate Cox regression model, gender and access side were included which failed to reach statistical significance.
    Conclusions: In our study, both right- and left-sided approaches provided similar safety and efficacy outcomes, suggesting that both techniques can be employed based on physician's preference.
    Language English
    Publishing date 2021-04-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603082-8
    ISSN 1432-086X ; 0342-7196 ; 0174-1551
    ISSN (online) 1432-086X
    ISSN 0342-7196 ; 0174-1551
    DOI 10.1007/s00270-021-02843-z
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  9. Article: Unique imaging appearance of neurosarcoidosis as a solitary cystic mass with mural enhancement.

    Bathla, Girish / Kandemirli, Sedat Giray / Gupta, Sarika / Agarwal, Amit

    Surgical neurology international

    2020  Volume 11, Page(s) 463

    Abstract: Background: Sarcoidosis is an idiopathic, granulomatous, and multi-system inflammatory disorder that can also involve the central nervous system in the form of meningeal, parenchymal, or cranial nerve involvement. Imaging findings can be non-specific ... ...

    Abstract Background: Sarcoidosis is an idiopathic, granulomatous, and multi-system inflammatory disorder that can also involve the central nervous system in the form of meningeal, parenchymal, or cranial nerve involvement. Imaging findings can be non-specific and may overlap with other inflammatory, infectious and neoplastic processes, and posing diagnostic challenges. Parenchymal involvement in neurosarcoidosis (NS) predominantly manifests as either non-enhancing white matter lesions or as enhancing parenchymal granulomas. Granulomas usually manifest as multiple solid lesions with nodular enhancement.
    Case description: A 72-year-old man presented with right-eye visual field changes with the non-contrast head computed tomography showing a large cystic lesion in the left frontoparietal lobe. Subsequent contrast-enhanced magnetic resonance imaging study revealed a large cystic mass with irregular rim enhancement and mural nodule concerning for glial neoplasm. Cyst decompression with biopsy and histopathological analysis revealed gliosis and prominent perivascular granulomatous inflammation with mixed picture of CD4 and CD8-positive cells suggestive of sarcoidosis. Further subsequent work-up showed mediastinal and cervical lymphadenopathy which on biopsy showed non-necrotizing granulomatous inflammation, consistent with sarcoidosis.
    Conclusion: Herein, we report unique imaging findings of a NS case manifesting as a solitary cystic intraparenchymal lesion with an enhancing nodular component, mimicking primary intra-cranial tumor. This appearance is highly atypical and rarely been reported earlier.
    Language English
    Publishing date 2020-12-22
    Publishing country United States
    Document type Case Reports
    ISSN 2229-5097
    ISSN 2229-5097
    DOI 10.25259/SNI_830_2020
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  10. Article: Central venous catheter insertion into the false lumen of a complicated aortic dissection.

    Bas, Ahmet / Goksedef, Deniz / Kandemirli, Sedat G / Gulsen, Fatih / Numan, Furuzan

    Scottish medical journal

    2017  Volume 62, Issue 3, Page(s) 115–118

    Abstract: Thoracic endovascular repair is considered the first-line treatment in complicated acute type B dissection. Central venous catheters provide valuable vascular access during endovascular treatments. However, central venous catheters are not without ... ...

    Abstract Thoracic endovascular repair is considered the first-line treatment in complicated acute type B dissection. Central venous catheters provide valuable vascular access during endovascular treatments. However, central venous catheters are not without complications. Herein, we report a case of central venous catheter insertion into the false lumen of a complicated acute type B aortic dissection by direct aortic puncture. The tip of the central venous catheter was in the false lumen. The central venous catheter was left in place initially and was removed after graft stent deployment. This case illustrates the importance of image guidance during central venous catheter insertion, which may further complicate an already complicated aortic dissection case.
    MeSH term(s) Aneurysm, Dissecting/diagnostic imaging ; Aneurysm, Dissecting/physiopathology ; Aneurysm, Dissecting/surgery ; Catheterization, Central Venous/methods ; Central Venous Catheters ; Endovascular Procedures/methods ; Humans ; Male ; Middle Aged ; Paraplegia/physiopathology ; Postoperative Complications/diagnostic imaging ; Postoperative Complications/physiopathology ; Radiographic Image Interpretation, Computer-Assisted ; Stents ; Tomography, X-Ray Computed ; Treatment Outcome ; Vascular Remodeling
    Language English
    Publishing date 2017-08
    Publishing country Scotland
    Document type Case Reports ; Journal Article
    ZDB-ID 414085-0
    ISSN 2045-6441 ; 0036-9330
    ISSN (online) 2045-6441
    ISSN 0036-9330
    DOI 10.1177/0036933017715962
    Database MEDical Literature Analysis and Retrieval System OnLINE

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