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Article ; Online: Sharing Lived Experiences of HIV Stigmatization: Process of Disseminating a Traveling Photovoice Exhibit.

Pichon, Latrice C / Jewell, Erin N / Diehl, Reighan E / Stubbs, Andrea W / Thompson, Daniel E / Hurd-Sawyer, LaRonia / Campbell, Bettina / Teti, Michelle

Journal of health care for the poor and underserved

2024 Volume 34, Issue 3S, Page(s) 57–68

Abstract: A Memphis-based, community-academic partnership created Snap Out Stigma, a photovoice project, to understand lived experiences of HIV stigma among people with HIV. This report describes traveling photovoice exhibit dissemination strategies, lessons ... ...

Abstract	A Memphis-based, community-academic partnership created Snap Out Stigma, a photovoice project, to understand lived experiences of HIV stigma among people with HIV. This report describes traveling photovoice exhibit dissemination strategies, lessons learned, and goals for the future of photovoice dissemination activities and community engagement in Memphis.
MeSH term(s)	Humans ; HIV Infections/psychology ; Photography ; Social Stigma ; Community-Institutional Relations ; Stereotyping ; Exhibitions as Topic ; Information Dissemination/methods
Language	English
Publishing date	2024-04-25
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1142637-8
ISSN	1548-6869 ; 1049-2089
ISSN (online)	1548-6869
ISSN	1049-2089
DOI	10.1353/hpu.2023.a903352
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Article ; Online: Healthcare professionals' perceptions and experiences of physiotherapy for people with mental illness: a protocol for a systematic review and meta-ethnography.

Hemmings, Laura / Heneghan, Nicola R / Byrd, Erin / Stubbs, Brendon / Soundy, Andrew

BMJ open

2022 Volume 12, Issue 8, Page(s) e061227

Abstract: Introduction: There is a high global prevalence of patients presenting with physical and mental health comorbidities. Physiotherapeutic interventions, such as exercise, can have positive benefits for physical and mental health. However, poor ... ...

Abstract	Introduction: There is a high global prevalence of patients presenting with physical and mental health comorbidities. Physiotherapeutic interventions, such as exercise, can have positive benefits for physical and mental health. However, poor accessibility and negative experiences of healthcare services for those with mental illness (MI) have been consistently observed within literature with recent research identifying poor experiences of physiotherapeutic interactions and processes such as referrals and discharges. One way to help improve physiotherapy services for this population is to understand the personal experiences and perceptions of healthcare professionals (HCPs) toward physiotherapy for patients with MI. Qualitative-based evidence syntheses are suited to bring this data together with the aim of improving physiotherapy services for patients with MI. This review will systematically search and synthesise existing evidence around HCP experiences and perceptions of physiotherapy for people with MI. Methods and analysis: A systematic search and seven-phase meta-ethnography will be undertaken. A comprehensive search of electronic databases (CINAHL plus, MEDLINE, Pubmed, Embase and Psycinfo) and search engines as well as grey literature (unpublished primary research such as theses) will be completed. Searches are planned to take place in July 2022. Eligibility criteria include: (a) qualitative data, (b) perceptions identified from HCP, including physiotherapists, assistants and HCP referring into physiotherapy, about physiotherapy for patients with MI and (c) are primary studies. Ethics and dissemination: This work is exempt from requiring ethical approval due to review methodology with data accessed from published works. This systematic review is expected to provide insight into experiences and perceptions of HCP around benefits and barriers to accessing physiotherapy for patients with mental health illness. Findings will be used to inform further research and co-develop recommendations to overcome barriers and optimise facilitators to care for this population. Findings will be disseminated via peer-reviewed journal, conference presentations and to key stakeholder groups. Prospero registration number: CRD42021293035.
MeSH term(s)	Anthropology, Cultural ; Delivery of Health Care ; Health Personnel/psychology ; Humans ; Mental Disorders/therapy ; Meta-Analysis as Topic ; Physical Therapy Modalities ; Systematic Reviews as Topic
Language	English
Publishing date	2022-08-24
Publishing country	England
Document type	Journal Article
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2022-061227
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Article ; Online: Association of mentally-active and mentally-passive sedentary behaviour with depressive symptoms among adolescents.

Werneck, André O / Hoare, Erin / Stubbs, Brendon / van Sluijs, Esther M F / Corder, Kirsten

Journal of affective disorders

2021 Volume 294, Page(s) 143–150

Abstract: Background: The evidence on the association between sedentary behaviour and depression in adolescence is mixed. We aimed to investigate the association between mentally-active and mentally-passive sedentary behaviours at 11 years (11y) and depressive ... ...

Abstract	Background: The evidence on the association between sedentary behaviour and depression in adolescence is mixed. We aimed to investigate the association between mentally-active and mentally-passive sedentary behaviours at 11 years (11y) and depressive symptoms at 14y, and to examine potential mediators. Methods: UK Millennium Cohort Study data were used (n=7,124; 49% boys). At 11y, participants self-reported frequency of mentally-passive (listening to music, internet use) and mentally-active sedentary behaviours (reading, playing electronic games). Additional parental-reported behaviours (mentally-passive: TV viewing; mentally-active: homework) were summed with self-reported behaviours to represent continuous indicators of mentally-active and mentally-passive sedentary behaviour. Depressive symptoms were assessed (at 11y and 14y) using the short-version of Mood and Feelings Questionnaire. Body mass index (BMI), mentally-passive sedentary behaviour and cognition at 14y were examined as potential mediators. Linear regression models were adjusted for confounders and stratified by sex. Subsequent mediation analyses reporting e-values were used to assess unmeasured confounding. Results: Among girls, mentally-passive sedentary behaviour at 11y was associated with later depressive symptoms (14y) [β:0.089 (95%CI:0.055-0.122), e-value:1.32]. This association was mediated by BMI [5.6% (95%CI:4.1%-8.6%)] and mentally-passive sedentary behaviour [105.6% (95%CI:79.6%-156.7%)]. No associations were observed in boys or between mentally-active sedentary behaviour and later depressive symptoms. Limitations: The parental report of behaviours and the assessment of mediators and outcome in the same wave are the main limitations. Conclusion: Future interventions aiming to improve mental health among girls could aim to reduce mentally-passive sedentary behaviour in early teens and could target potential mediators including BMI.
MeSH term(s)	Adolescent ; Cohort Studies ; Depression/epidemiology ; Female ; Humans ; Male ; Sedentary Behavior ; Self Report ; Surveys and Questionnaires
Language	English
Publishing date	2021-07-13
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	135449-8
ISSN	1573-2517 ; 0165-0327
ISSN (online)	1573-2517
ISSN	0165-0327
DOI	10.1016/j.jad.2021.07.004
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Article ; Online: Associations between mentally-passive and mentally-active sedentary behaviours during adolescence and psychological distress during adulthood.

Werneck, André O / Hoare, Erin / Stubbs, Brendon / van Sluijs, Esther M F / Corder, Kirsten

Preventive medicine

2021 Volume 145, Page(s) 106436

Abstract: It is unclear if different types of sedentary behaviour during the adolescence are differentially associated with psychological distress during adolescence and adulthood. It is also unknown what may mediate this potential proposed association. The ... ...

Abstract	It is unclear if different types of sedentary behaviour during the adolescence are differentially associated with psychological distress during adolescence and adulthood. It is also unknown what may mediate this potential proposed association. The current study aimed to analyse the association of mentally-active and mentally-passive sedentary behaviours during adolescence (16y) with subsequent psychological distress during adulthood (42y), and to examine the role of potential mediators (42y). Data from the 1970 British Cohort Study was used (N = 1787). At age 16y participants reported time and frequency in mentally-passive (TV-viewing and watching movies) and mentally-active (reading books, doing homework and playing computer games) sedentary behaviours, psychological distress and organized sports participation. At 42y, participants reported cognition (vocabulary test), TV-viewing, psychological distress, self-rated health, body mass index and employment status. Education was collected throughout the follow-up years. Logistic regression and mediation models assessed associations. Multiple imputation using chained equations was used to assess the impact of missing data. Mentally-passive sedentary behaviour in adolescence was a risk factor for psychological distress during adulthood in complete-cases analysis [OR:1.44(95%CI:1.09-1.90)], which was confirmed by the model with multiple imputation. Mentally-active sedentary behaviour at 16y was not associated with psychological distress at 42y. Adult TV-viewing during weekends (24.7%), and self-rated health (19.0%) mediated the association between mentally-passive sedentary behaviour during adolescence and psychological distress during adulthood. However, the mediation was not clear in the models with multiple imputation. Mentally-passive sedentary behaviour during adolescence was associated with elevated psychological distress during adulthood and this association was mediated TV-viewing and self-rated health in adulthood.
MeSH term(s)	Adolescent ; Adult ; Body Mass Index ; Cohort Studies ; Humans ; Psychological Distress ; Sedentary Behavior ; Sports ; Television
Language	English
Publishing date	2021-01-22
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	184600-0
ISSN	1096-0260 ; 0091-7435
ISSN (online)	1096-0260
ISSN	0091-7435
DOI	10.1016/j.ypmed.2021.106436
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Article ; Online: Recurrent Rash in an 11-Year-Old Boy With Pericardial and Pleural Effusions.

Weisnicht, Allison M / Byrne, Ryan / Henkel, Erin B / Harding, Stephen A / Kostelyna, Stefan P / Schady, Deborah / Lai, Jamie / Stubbs, Leigh A

Pediatrics

2022 Volume 150, Issue 5

Abstract: An 11-year-old, previously healthy boy presented to the emergency center (EC) for acute respiratory distress in the setting of 5 months of recurrent and worsening rash with progressive fatigue, shortness of breath, chest pain, and cough. At the onset of ... ...

Abstract	An 11-year-old, previously healthy boy presented to the emergency center (EC) for acute respiratory distress in the setting of 5 months of recurrent and worsening rash with progressive fatigue, shortness of breath, chest pain, and cough. At the onset of his rash, he and his younger brothers were diagnosed with roseola. Although his brothers' symptoms resolved, the patient's rash recurred, prompting his primary care provider to prescribe amoxicillin. The rash subsequently worsened, so amoxicillin was stopped; a prednisone course was prescribed which alleviated the rash. Upon completion of the prednisone course, the rash returned more diffusely with associated symptoms of shortness of breath, chest pain, and cough. Because of these symptoms, his mother brought him to the EC, where his vitals were notable for tachypnea and tachycardia. His initial EC imaging workup was remarkable for an echocardiogram with a mild to moderate circumferential pericardial effusion, chest x-ray (CXR) with a large right pleural effusion, and chest computerized tomography significant for prominent and diffuse mediastinal and hilar lymphadenopathy with numerous enlarged axillary lymph nodes. Laboratory results were notable for elevated liver enzymes, inflammatory markers, d-dimer, and brain natriuretic peptide. Differential diagnosis remained broad, including infectious, oncologic, and rheumatologic etiologies. Our panel of experts reviews the evaluation, hospital course, and treatment of this patient presenting with an unusual rash and serositis.
MeSH term(s)	Humans ; Male ; Child ; Cough ; Prednisone ; Pleural Effusion ; Exanthema/etiology ; Chest Pain/etiology ; Dyspnea ; Amoxicillin
Chemical Substances	Prednisone (VB0R961HZT) ; Amoxicillin (804826J2HU)
Language	English
Publishing date	2022-10-28
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	207677-9
ISSN	1098-4275 ; 0031-4005
ISSN (online)	1098-4275
ISSN	0031-4005
DOI	10.1542/peds.2021-055524
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Article ; Online: An Engaged Community of Faith to Decrease HIV Stigma in the U.S. South.

Pichon, Latrice C / Jewell, Erin N / Williams Stubbs, Andrea / Jones, DeMarcus / Campbell, Bettina / Kimble, Katrina M / Stewart, Gina M / Hurd-Sawyer, LaRonia / Carroll, Lacretia / Powell, Terrinieka W

International journal of environmental research and public health

2023 Volume 20, Issue 3

Abstract: Community members from a city in the U.S. Deep South identified root causes of HIV racial disparities, including stigma. This meeting report describes how we developed and implemented a conference series to address HIV stigma. We used community feedback ... ...

Abstract	Community members from a city in the U.S. Deep South identified root causes of HIV racial disparities, including stigma. This meeting report describes how we developed and implemented a conference series to address HIV stigma. We used community feedback and bidirectional learning to host two meetings in observance of National HIV Testing Day (June 2021) and National Southern HIV/AIDS Awareness Day (August 2021). We established a 10-member organizing committee workgroup that met monthly to plan the Faith Summit in honor of National Black HIV Awareness Day (February 2022). Lessons learned include (a) the effectiveness of different community engagement strategies, including participatory evaluative approaches, and (b) strategies to maintain engagement and increase participation, such as reliance on personal and professional networks and prompting the community about forthcoming interventions. Sustaining a conference series to end HIV stigma requires commitment and inclusive participation. This collaborative project offers additional evidence that faith communities can be a part of the solution to ending the HIV epidemic and related health disparities.
MeSH term(s)	Humans ; HIV Infections/epidemiology ; HIV Infections/prevention & control ; Acquired Immunodeficiency Syndrome ; Population Groups ; Social Stigma
Language	English
Publishing date	2023-01-24
Publishing country	Switzerland
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph20032100
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Article ; Online: An Engaged Community of Faith to Decrease HIV Stigma in the U.S. South

Latrice C. Pichon / Erin N. Jewell / Andrea Williams Stubbs / DeMarcus Jones / Bettina Campbell / Katrina M. Kimble / Gina M. Stewart / LaRonia Hurd-Sawyer / Lacretia Carroll / Terrinieka W. Powell

International Journal of Environmental Research and Public Health, Vol 20, Iss 2100, p

2023 Volume 2100

Abstract	Community members from a city in the U.S. Deep South identified root causes of HIV racial disparities, including stigma. This meeting report describes how we developed and implemented a conference series to address HIV stigma. We used community feedback and bidirectional learning to host two meetings in observance of National HIV Testing Day (June 2021) and National Southern HIV/AIDS Awareness Day (August 2021). We established a 10-member organizing committee workgroup that met monthly to plan the Faith Summit in honor of National Black HIV Awareness Day (February 2022). Lessons learned include (a) the effectiveness of different community engagement strategies, including participatory evaluative approaches, and (b) strategies to maintain engagement and increase participation, such as reliance on personal and professional networks and prompting the community about forthcoming interventions. Sustaining a conference series to end HIV stigma requires commitment and inclusive participation. This collaborative project offers additional evidence that faith communities can be a part of the solution to ending the HIV epidemic and related health disparities.
Keywords	faith ; HIV stigma ; community engagement ; CBPR ; virtual conference ; pandemic ; Medicine ; R
Subject code	306
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: Patient safety in ambulatory care.

Neuspiel, Daniel R / Stubbs, Erin H

Pediatric clinics of North America

2012 Volume 59, Issue 6, Page(s) 1341–1354

Abstract: Understanding of the types and frequency of errors among children in the outpatient setting is paramount. The most commonly described errors involve medical treatment, communication failures, patient identification, laboratory, and diagnostic errors. ... ...

Abstract	Understanding of the types and frequency of errors among children in the outpatient setting is paramount. The most commonly described errors involve medical treatment, communication failures, patient identification, laboratory, and diagnostic errors. Research suggests that adverse events and near misses are frequent occurrences in ambulatory pediatrics, but relatively little is known about the types of errors, risk factors, or effective interventions in this setting. This article will review current information on the descriptive epidemiology of pediatric outpatient medical errors, established risk factors for these errors, effective interventions to enhance reporting and improve safety, and future research needs in this area.
MeSH term(s)	Ambulatory Care/standards ; Child ; Humans ; Medical Errors/prevention & control ; Patient Safety ; Physicians ; Risk Factors ; Safety Management
Language	English
Publishing date	2012-12
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	215711-1
ISSN	1557-8240 ; 0031-3955
ISSN (online)	1557-8240
ISSN	0031-3955
DOI	10.1016/j.pcl.2012.08.006
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Article ; Online: Identification of a novel GR-ARID1a-P53BP1 protein complex involved in DNA damage repair and cell cycle regulation.

Stubbs, Felicity E / Flynn, Benjamin P / Rivers, Caroline A / Birnie, Matthew T / Herman, Andrew / Swinstead, Erin E / Baek, Songjoon / Fang, Hai / Temple, Jillian / Carroll, Jason S / Hager, Gordon L / Lightman, Stafford L / Conway-Campbell, Becky L

Oncogene

2022 Volume 41, Issue 50, Page(s) 5347–5360

Abstract: ARID1a (BAF250), a component of human SWI/SNF chromatin remodeling complexes, is frequently mutated across numerous cancers, and its loss of function has been putatively linked to glucocorticoid resistance. Here, we interrogate the impact of siRNA ... ...

Abstract	ARID1a (BAF250), a component of human SWI/SNF chromatin remodeling complexes, is frequently mutated across numerous cancers, and its loss of function has been putatively linked to glucocorticoid resistance. Here, we interrogate the impact of siRNA knockdown of ARID1a compared to a functional interference approach in the HeLa human cervical cancer cell line. We report that ARID1a knockdown resulted in a significant global decrease in chromatin accessibility in ATAC-Seq analysis, as well as affecting a subset of genome-wide GR binding sites determined by analyzing GR ChIP-Seq data. Interestingly, the specific effects on gene expression were limited to a relatively small subset of glucocorticoid-regulated genes, notably those involved in cell cycle regulation and DNA repair. The vast majority of glucocorticoid-regulated genes were largely unaffected by ARID1a knockdown or functional interference, consistent with a more specific role for ARID1a in glucocorticoid function than previously speculated. Using liquid chromatography-mass spectrometry, we have identified a chromatin-associated protein complex comprising GR, ARID1a, and several DNA damage repair proteins including P53 binding protein 1 (P53BP1), Poly(ADP-Ribose) Polymerase 1 (PARP1), DNA damage-binding protein 1 (DDB1), DNA mismatch repair protein MSH6 and splicing factor proline and glutamine-rich protein (SFPQ), as well as the histone acetyltransferase KAT7, an epigenetic regulator of steroid-dependent transcription, DNA damage repair and cell cycle regulation. Not only was this protein complex ablated with both ARID1a knockdown and functional interference, but spontaneously arising DNA damage was also found to accumulate in a manner consistent with impaired DNA damage repair mechanisms. Recovery from dexamethasone-dependent cell cycle arrest was also significantly impaired. Taken together, our data demonstrate that although glucocorticoids can still promote cell cycle arrest in the absence of ARID1a, the purpose of this arrest to allow time for DNA damage repair is hindered.
MeSH term(s)	Humans ; Cell Cycle ; Cell Cycle Checkpoints ; Cell Line, Tumor ; Chromatin/genetics ; DNA Damage ; DNA Repair ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Histone Acetyltransferases/metabolism ; Nuclear Proteins/metabolism ; Transcription Factors/genetics ; Receptors, Glucocorticoid/metabolism ; Tumor Suppressor p53-Binding Protein 1/metabolism
Chemical Substances	ARID1A protein, human ; Chromatin ; DNA-Binding Proteins ; Histone Acetyltransferases (EC 2.3.1.48) ; KAT7 protein, human (EC 2.3.1.48) ; Nuclear Proteins ; Transcription Factors ; Receptors, Glucocorticoid ; TP53BP1 protein, human ; Tumor Suppressor p53-Binding Protein 1
Language	English
Publishing date	2022-11-07
Publishing country	England
Document type	Journal Article
ZDB-ID	639046-8
ISSN	1476-5594 ; 0950-9232
ISSN (online)	1476-5594
ISSN	0950-9232
DOI	10.1038/s41388-022-02516-2
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Article ; Online: Transfusion-Transmitted Malaria: Two Pediatric Cases From the United States and Their Relevance in an Increasingly Globalized World.

Stubbs, Leigh A / Price, Michael / Noland, Daniel / Fuchs, Jennifer / Filkins, Laura / McElvania, Erin / Luu, Hung S / Sebert, Michael / Waters, Ami / Hsiang, Michelle S

Journal of the Pediatric Infectious Diseases Society

2021 Volume 10, Issue 12, Page(s) 1092–1095

Abstract: In non-endemic settings, transfusion-transmitted malaria (TTM) is rare but potentially fatal and becoming more common with globalization. We present two pediatric cases that demonstrate donor screening using questionnaires is subject to error and that ... ...

Abstract	In non-endemic settings, transfusion-transmitted malaria (TTM) is rare but potentially fatal and becoming more common with globalization. We present two pediatric cases that demonstrate donor screening using questionnaires is subject to error and that TTM should be considered with fever following numerous transfusions in children, particularly sickle cell patients.
MeSH term(s)	Blood Donors ; Blood Transfusion ; Child ; Fever ; Humans ; Malaria/epidemiology ; Transfusion Reaction ; United States/epidemiology
Language	English
Publishing date	2021-09-24
Publishing country	England
Document type	Journal Article
ZDB-ID	2668791-4
ISSN	2048-7207 ; 2048-7193
ISSN (online)	2048-7207
ISSN	2048-7193
DOI	10.1093/jpids/piab083
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