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Article ; Online: Dental Pain Medication Prescriptions in Minas Gerais, Brazil (2011-2021): A Time-Series Analysis.

Cruz, Alex Junio Silva / Martins, Maria Auxiliadora Parreiras / Batista, Victor Santos / de Aguilar Penido, Henrique Pereira / Santos, Jacqueline Silva / Dos Santos, Thiago Rezende / Sohn, Woosung / de Castilho, Lia Silva / Abreu, Mauro Henrique Nogueira Guimarães

International journal of environmental research and public health

2023 Volume 20, Issue 18

Abstract: To describe trends of dentist-prescribed non-steroidal anti-inflammatory drugs (NSAIDs) and analgesics, from January 2011 to December 2021, as well as to examine the relationship between these trends and characteristics of public oral health services in ... ...

Abstract	To describe trends of dentist-prescribed non-steroidal anti-inflammatory drugs (NSAIDs) and analgesics, from January 2011 to December 2021, as well as to examine the relationship between these trends and characteristics of public oral health services in Minas Gerais, Brazil. In this time-series analysis, all drugs were classified according to the Anatomical Therapeutic Chemical classification system. Drugs categorized as NSAIDs (M01A), and other analgesics and antipyretics (N02B) were included for analysis. The outcome was the number of Defined Daily Doses (DDDs)/1000 inhabitants/year for NSAIDs and analgesics in each town. Covariates referred to characteristics of public oral health services, such as coverage, estimates of dental procedures, and frequency of toothache. Linear time-series regression models were used to determine the influence of covariates on the outcome. Overall, there were 58,482 prescriptions of NSAIDs recorded in thirty-eight towns, while 47,499 prescriptions of analgesics in forty-three towns. For each year, there was a 0.38 (
MeSH term(s)	Humans ; Brazil/epidemiology ; Toothache/drug therapy ; Toothache/epidemiology ; Drug Prescriptions ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Research Design
Chemical Substances	Anti-Inflammatory Agents, Non-Steroidal
Language	English
Publishing date	2023-09-21
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph20186795
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: High prevalence of potential psychotropic drugs interactions among Brazilian dental patients.

Cruz, Alex Junio Silva / Martins, Maria Auxiliadora Parreiras / de Aguilar, Diego Rodrigues / Santos, Jacqueline Silva / Sohn, Woosung / de Castilho, Lia Silva / Abreu, Mauro Henrique Nogueira Guimarães

Oral diseases

2023

Abstract: Objective: To determine the prevalence of potential drug-drug interactions involving psychotropics prescribed by dentists, and dispensed by the public healthcare system, as well as to describe the severity and level of evidence of those interactions in ... ...

Abstract	Objective: To determine the prevalence of potential drug-drug interactions involving psychotropics prescribed by dentists, and dispensed by the public healthcare system, as well as to describe the severity and level of evidence of those interactions in the state of Minas Gerais, Brazil. Materials and methods: We conducted data analysis from pharmaceutical claims in which dental patients received systemic psychotropics in 2017. Data from the Pharmaceutical Management System provided the drug dispensing history of the patients, allowing the identification of those on concomitant medication use. The outcome was the occurrence of potential drug-drug interactions, which were detected according to IBM Micromedex®. Independent variables were the patient's sex, age, and the number of drugs used. Descriptive statistics was performed using SPSS v. 26. Results: Overall, 1480 individuals were prescribed psychotropic drugs. The prevalence of potential drug-drug interactions was 24.8% (n = 366). The total of 648 interactions was observed and, most of which were of major severity (n = 438, 67.6%). Most interactions occurred in female individuals (n = 235; 64.2%), with 46.0 (±17.3) years-old, concurrently taking 3.7 (±1.9) drugs. Conclusion: A substantial proportion of dental patients presented potential drug-drug interactions, mostly of major severity, which might be life-threatening.
Language	English
Publishing date	2023-02-16
Publishing country	Denmark
Document type	Journal Article
ZDB-ID	1290529-x
ISSN	1601-0825 ; 1354-523X
ISSN (online)	1601-0825
ISSN	1354-523X
DOI	10.1111/odi.14539
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Zs.A 4427: Show issues

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Article ; Online: Association of sociodemographic factors with the prescription pattern of opioids for dental patients: a systematic review.

Cruz, Alex Junio Silva / Abreu, Lucas Guimarães / da Rocha Mendes, Suellen / de Castilho, Lia Silva / de Abreu, Mauro Henrique Nogueira Guimarães

Evidence-based dentistry

2022

Abstract: Aim To evaluate the association of patients' sociodemographic factors (sex, age, ethnicity, income, educational level, living environment and health insurance) with the prescription pattern of opioids provided by oral health practitioners.Methods ... ...

Abstract	Aim To evaluate the association of patients' sociodemographic factors (sex, age, ethnicity, income, educational level, living environment and health insurance) with the prescription pattern of opioids provided by oral health practitioners.Methods Observational studies that evaluated the association of patients' sociodemographic factors and the likelihood of receiving an opioid prescription provided by an oral health practitioner were eligible. Electronic searches were conducted in Medline (PubMed), Embase, Scopus, Web of Science, LILACS, SciELO, Google Scholar, and OpenGrey up to March 2021. Two authors independently screened the studies, performed data extraction, and assessed the risk-of-bias using the critical appraisal tools developed by the Joanna Briggs Institute (JBI). Certainty of the evidence was assessed with the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE).Results Eight studies were included in this systematic review. Publication year ranged from 2011 to 2021. Narrative synthesis showed with very low certainty of evidence that younger individuals were more likely to receive a prescription of opioids than older individuals. Regarding the other sociodemographic factors and the prescriptions of opioids in dentistry, the evidence is controversial. Risk of bias was low for most items assessed in the included studies.Conclusion The available evidence suggests that there is an association between patients' sociodemographic factors and the prescription patterns of opioids provided by oral health practitioners.
Language	English
Publishing date	2022-09-06
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	1457588-7
ISSN	1476-5446 ; 1462-0049
ISSN (online)	1476-5446
ISSN	1462-0049
DOI	10.1038/s41432-022-0282-7
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Zs.A 4972: Show issues

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Article ; Online: Breathing problems and COVID-19 in patients with developmental disabilities.

de Castilho, Lia Silva / Lages, Frederico Dos Santos / Ferreira, Rauel Victor Dutra / de Oliveira, Ana Cristina Borges / Vilaça, Ênio Lacerda / Diniz, Ivana Márcia Alves

Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry

2020 Volume 40, Issue 5, Page(s) 529–530

MeSH term(s)	COVID-19 ; Child ; Developmental Disabilities ; Humans ; Respiration ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-08-03
Publishing country	United States
Document type	Letter
ZDB-ID	604118-8
ISSN	1754-4505 ; 0275-1879
ISSN (online)	1754-4505
ISSN	0275-1879
DOI	10.1111/scd.12504
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Zs.B 2515: Show issues

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Article ; Online: Association of sociodemographic factors with the prescription pattern of opioids for dental patients: A systematic review protocol.

Cruz, Alex Junio Silva / Abreu, Lucas Guimarães / Mendes, Suellen da Rocha / Castilho, Lia Silva de / Abreu, Mauro Henrique Nogueira Guimarães de

PloS one

2021 Volume 16, Issue 8, Page(s) e0255743

Abstract: Introduction: Oral health practitioners are responsible for a significant share of opioid prescriptions that seem to be influenced by many aspects, including sociodemographic factors. However, there is no consensus on the factors associated with opioid ... ...

Abstract	Introduction: Oral health practitioners are responsible for a significant share of opioid prescriptions that seem to be influenced by many aspects, including sociodemographic factors. However, there is no consensus on the factors associated with opioid prescription in Dentistry. Objective: To identify whether patients' sociodemographic factors are associated with the prescription pattern of opioids in Dentistry. Materials and methods: This systematic review will include observational studies (cross-sectional, case-control, and cohort). Electronic searches will be conducted in MEDLINE (PubMed), EMBASE, Scopus, Web of science, LILACS, SciELO, and Google Scholar. Grey literature will also be consulted. Two independent reviewers will screen all retrieved articles for eligibility, extract data, and assess the methodological quality of the included studies. The results will be presented as a narrative synthesis and, where possible, a meta-analysis will be conducted. Certainty of the evidence will be assessed with the Grading of Recommendations, Assessment, Development, and Evaluation approach. Systematic review registration number: PROSPERO CRD42020211226.
MeSH term(s)	Analgesics, Opioid/administration & dosage ; Dental Care/statistics & numerical data ; Drug Prescriptions/statistics & numerical data ; Drug Utilization/statistics & numerical data ; Humans ; Observational Studies as Topic ; Socioeconomic Factors ; Systematic Reviews as Topic
Chemical Substances	Analgesics, Opioid
Language	English
Publishing date	2021-08-05
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0255743
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Carious lesions recurrence in children with developmental disabilities: a longitudinal study.

Castilho, Lia Silva de / Diniz, Ivana Márcia Alves / Santos, Bruno Pereira Dos Reis / Lages, Frederico Santos / Cruz, Alex Júnio Silva da / Abreu, Mauro Henrique Nogueira Guimarães

Brazilian oral research

2021 Volume 35, Page(s) e071

Abstract: This study investigated the factors associated with new carious lesions in one-to five-year-old children with developmental disabilities. This was a retrospective cohort that evaluated 64 dental charts of individuals with caries or fillings in their ... ...

Abstract	This study investigated the factors associated with new carious lesions in one-to five-year-old children with developmental disabilities. This was a retrospective cohort that evaluated 64 dental charts of individuals with caries or fillings in their first dental appointment. The dependent variable was the occurrence of a new carious lesion or restoration. Gender, age, mother's education, sugar consumption, oral hygiene, mouth breathing, reports of xerostomia, gingival status, use of psychotropic drugs, use of asthma drugs, history of asthma, bronchitis, reflux or seizures and having at least one sibling were covariates. Cox proportional hazards regression model was used to estimate the raw and adjusted hazard ratios with their respective 95% confidence interval. The average time that individuals remained free of dental caries/restoration was 79.49 months (95%CI: 64.37 to 92.61). Increase in sucrose consumption increased the rate of caries recurrence (HR = 1.16; 95%CI: 1.04 to 1.30). Individuals who had poor oral hygiene had higher rate of new dental caries (HR = 3.88; 95%CI: 1.22 to 12.37) compared to those with good oral hygiene. The presence of mouth breathing decreased the rate of recurrence of the disease when compared to the nasal breathing (HR = 0.32; 95%CI: 0.15 to 0.70). Oral health-related behaviors and nasal respiration influenced the rate of dental caries recurrence in individuals with developmental disabilities.
MeSH term(s)	Child ; Child, Preschool ; Dental Caries/epidemiology ; Developmental Disabilities/epidemiology ; Humans ; Infant ; Longitudinal Studies ; Oral Hygiene ; Retrospective Studies
Language	English
Publishing date	2021-09-03
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2179332-3
ISSN	1807-3107 ; 1806-8324 ; 1517-7491
ISSN (online)	1807-3107
ISSN	1806-8324 ; 1517-7491
DOI	10.1590/1807-3107bor-2021.vol35.0071
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Zs.A 3037: Show issues

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Article: Breathing problems and COVID-19 in patients with developmental disabilities

de Castilho, Lia Silva / Lages, Frederico Dos Santos / Ferreira, Rauel Victor Dutra / de Oliveira, Ana Cristina Borges / Vilaça, Ênio Lacerda / Diniz, Ivana Márcia Alves

Spec. care dentist

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #691899
Database	COVID19

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Article ; Online: What Increases the Risk of Dental Traumatism in Patients with Developmental Disabilities?

Souza, Xana Carolina de Pereira E / Abreu, Mauro Henrique Nogueira Guimarães / Resende, Vera Lúcia Silva / Castilho, Lia Silva de

Brazilian dental journal

2018 Volume 29, Issue 2, Page(s) 154–158

Abstract: This study investigated risk factors for tooth injuries in individuals from a dental clinical reference service for patients with special needs in Belo Horizonte, MG, Brazil. This is a retrospective cohort study that evaluated 493 dental charts of ... ...

Abstract	This study investigated risk factors for tooth injuries in individuals from a dental clinical reference service for patients with special needs in Belo Horizonte, MG, Brazil. This is a retrospective cohort study that evaluated 493 dental charts of individuals with or without tooth injuries at their first dental appointment. The dependent variable was the time of occurrence of new dental traumatic injuries and was measured in months. Gender, age, International Code of Diseases, mother's education, mouth breathing, hyperkinesis, pacifier use, thumb sucking, psychotropic drug use, tooth injuries at the first dental examination, involuntary movements, open bite, having one or more siblings and reports of seizures were the covariates. The Cox proportional hazards regression model was used to estimate the unadjusted and adjusted hazard ratios and their respective 95% confidence intervals. The average time that individuals remained free of dental traumatism was 170.78 months (95% CI, 157.89-183.66) with median of 216 months. The incidence of new events was 11.88%. The covariate associated with an increased risk of dental traumatism was a history of tooth injuries at the first dental appointment. The increase in dental trauma risk was 3.59 (95% CI, 1.94-6.65). A history of traumatic dental injury was the risk factor for the dental trauma found in this group of individuals with developmental disabilities.
MeSH term(s)	Adolescent ; Adult ; Brazil/epidemiology ; Child ; Child, Preschool ; Dental Care for Disabled ; Dental Health Services/organization & administration ; Developmental Disabilities/epidemiology ; Female ; Humans ; Incidence ; Infant ; Infant, Newborn ; Male ; Prevalence ; Proportional Hazards Models ; Retrospective Studies ; Risk Factors ; Tooth Injuries/epidemiology ; Tooth Injuries/therapy ; Young Adult
Language	English
Publishing date	2018-06-13
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	1089484-6
ISSN	1806-4760 ; 0103-6440
ISSN (online)	1806-4760
ISSN	0103-6440
DOI	10.1590/0103-6440201801922
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 3335: Show issues

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Article ; Online: Uso de radiografias panorâmicas no programa de assistência odontológica a pacientes de transplante da UFMG

Maria Elisa Souza e Silva / Luanne Priscila Pereira Avelar / Ellen Marise Castro Oliveira / Tânia Mara Pimenta do Amaral / Jéssica Alves de Borba / Lia Silva de Castilho

Extensio: Revista Eletrônica de Extensão, Vol 18, Iss

2021 Volume 40

Abstract: A radiografia panorâmica é usada para a avaliação do estado dos dentes e osso dos maxilares, em uma visão global dessas estruturas de uma só vez. O objetivo deste estudo é caracterizar os pacientes e levantar aspectos radiográficos relevantes observados ... ...

Abstract	A radiografia panorâmica é usada para a avaliação do estado dos dentes e osso dos maxilares, em uma visão global dessas estruturas de uma só vez. O objetivo deste estudo é caracterizar os pacientes e levantar aspectos radiográficos relevantes observados nas radiografias panorâmicas dos pacientes do Programa de Extensão Assistência Odontológica a Pacientes de Transplante da UFMG. Foram estudadas radiografias panorâmicas desde 2016. A análise estatística se deu por descrição dos resultados e análises bivariadas, empregando-se o teste do qui-quadrado e teste exato de Fischer, Mann-Whitney e Kruskal-Wallis. Foram considerados significativos os resultados com p< 0,05. Em relação à faixa etária, foi observada uma associação significativa com a avaliação da raiz residual, nível ósseo e relação da cúpula alveolar. A radiografia panorâmica contribui para a compreensão de problemas, acelerando o estabelecimento do plano de tratamento, especialmente entre pacientes que estejam na fase pré-transplante de fígado, rins ou células hematopoiéticas.
Keywords	Transplante de Fígado ; Transplante de Células-Tronco Hematopoéticas ; Transplante de Rim ; Assistência Odontológica ; Radiografia Panorâmica ; Medicine ; R ; Science ; Q ; Social Sciences ; H
Language	Portuguese
Publishing date	2021-12-01T00:00:00Z
Publisher	Universidade Federal de Santa Catarina
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Association of sociodemographic factors with the prescription pattern of opioids for dental patients

Alex Junio Silva Cruz / Lucas Guimarães Abreu / Suellen da Rocha Mendes / Lia Silva de Castilho / Mauro Henrique Nogueira Guimarães de Abreu

PLoS ONE, Vol 16, Iss

A systematic review protocol

2021 Volume 8

Abstract: Introduction Oral health practitioners are responsible for a significant share of opioid prescriptions that seem to be influenced by many aspects, including sociodemographic factors. However, there is no consensus on the factors associated with opioid ... ...

Abstract	Introduction Oral health practitioners are responsible for a significant share of opioid prescriptions that seem to be influenced by many aspects, including sociodemographic factors. However, there is no consensus on the factors associated with opioid prescription in Dentistry. Objective To identify whether patients’ sociodemographic factors are associated with the prescription pattern of opioids in Dentistry. Materials and methods This systematic review will include observational studies (cross-sectional, case-control, and cohort). Electronic searches will be conducted in MEDLINE (PubMed), EMBASE, Scopus, Web of science, LILACS, SciELO, and Google Scholar. Grey literature will also be consulted. Two independent reviewers will screen all retrieved articles for eligibility, extract data, and assess the methodological quality of the included studies. The results will be presented as a narrative synthesis and, where possible, a meta-analysis will be conducted. Certainty of the evidence will be assessed with the Grading of Recommendations, Assessment, Development, and Evaluation approach. Systematic review registration number PROSPERO CRD42020211226.
Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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