LIVIVO - Search results -

Search results

Result 1 - 10 of total 12

Search options

Article ; Online: Mucociliary transport deficiency and disease progression in Syrian hamsters with SARS-CoV-2 infection

Qian Li / Kadambari Vijaykumar / Scott E. Phillips / Shah S. Hussain / Nha V. Huynh / Courtney M. Fernandez-Petty / Jacelyn E. Peabody Lever / Jeremy B. Foote / Janna Ren / Javier Campos-Gómez / Farah Abou Daya / Nathaniel W. Hubbs / Harrison Kim / Ezinwanne Onuoha / Evan R. Boitet / Lianwu Fu / Hui Min Leung / Linhui Yu / Thomas W. Detchemendy /

Levi T. Schaefers / Jennifer L. Tipper / Lloyd J. Edwards / Sixto M. Leal Jr. / Kevin S. Harrod / Guillermo J. Tearney / Steven M. Rowe

JCI Insight, Vol 8, Iss

2023 Volume 1

Abstract: Substantial clinical evidence supports the notion that ciliary function in the airways is important in COVID-19 pathogenesis. Although ciliary damage has been observed in both in vitro and in vivo models, the extent or nature of impairment of mucociliary ...

Abstract	Substantial clinical evidence supports the notion that ciliary function in the airways is important in COVID-19 pathogenesis. Although ciliary damage has been observed in both in vitro and in vivo models, the extent or nature of impairment of mucociliary transport (MCT) in in vivo models remains unknown. We hypothesize that SARS-CoV-2 infection results in MCT deficiency in the airways of golden Syrian hamsters that precedes pathological injury in lung parenchyma. Micro-optical coherence tomography was used to quantitate functional changes in the MCT apparatus. Both genomic and subgenomic viral RNA pathological and physiological changes were monitored in parallel. We show that SARS-CoV-2 infection caused a 67% decrease in MCT rate as early as 2 days postinfection (dpi) in hamsters, principally due to 79% diminished airway coverage of motile cilia. Correlating quantitation of physiological, virological, and pathological changes reveals steadily descending infection from the upper airways to lower airways to lung parenchyma within 7 dpi. Our results indicate that functional deficits of the MCT apparatus are a key aspect of COVID-19 pathogenesis, may extend viral retention, and could pose a risk factor for secondary infection. Clinically, monitoring abnormal ciliated cell function may indicate disease progression. Therapies directed toward the MCT apparatus deserve further investigation.
Keywords	COVID-19 ; Medicine ; R
Subject code	570
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	American Society for Clinical investigation
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Tandem chemical deconstruction and biological upcycling of poly(ethylene terephthalate) to β-ketoadipic acid by Pseudomonas putida KT2440.

Werner, Allison Z / Clare, Rita / Mand, Thomas D / Pardo, Isabel / Ramirez, Kelsey J / Haugen, Stefan J / Bratti, Felicia / Dexter, Gara N / Elmore, Joshua R / Huenemann, Jay D / Peabody, George L / Johnson, Christopher W / Rorrer, Nicholas A / Salvachúa, Davinia / Guss, Adam M / Beckham, Gregg T

Metabolic engineering

2021 Volume 67, Page(s) 250–261

Abstract: Poly(ethylene terephthalate) (PET) is the most abundantly consumed synthetic polyester and accordingly a major source of plastic waste. The development of chemocatalytic approaches for PET depolymerization to monomers offers new options for open-loop ... ...

Abstract	Poly(ethylene terephthalate) (PET) is the most abundantly consumed synthetic polyester and accordingly a major source of plastic waste. The development of chemocatalytic approaches for PET depolymerization to monomers offers new options for open-loop upcycling of PET, which can leverage biological transformations to higher-value products. To that end, here we perform four sequential metabolic engineering efforts in Pseudomonas putida KT2440 to enable the conversion of PET glycolysis products via: (i) ethylene glycol utilization by constitutive expression of native genes, (ii) terephthalate (TPA) catabolism by expression of tphA2
MeSH term(s)	Adipates ; Burkholderiales ; Ethylenes ; Hydrolases ; Phthalic Acids ; Polyethylene Terephthalates ; Pseudomonas putida/genetics ; Rhodococcus
Chemical Substances	Adipates ; Ethylenes ; Phthalic Acids ; Polyethylene Terephthalates ; 3-oxoadipic acid (1379JRA56F) ; terephthalic acid (6S7NKZ40BQ) ; Hydrolases (EC 3.-)
Language	English
Publishing date	2021-07-12
Publishing country	Belgium
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	1470383-x
ISSN	1096-7184 ; 1096-7176
ISSN (online)	1096-7184
ISSN	1096-7176
DOI	10.1016/j.ymben.2021.07.005
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6288: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Corrigendum to "Engineering glucose metabolism for enhanced muconic acid production in Pseudomonas putida KT2440" [Metab. Eng. 59 (2020) 64-75].

Bentley, Gayle J / Narayanan, Niju / Jha, Ramesh K / Salvachúa, Davinia / Elmore, Joshua R / Peabody, George L / Black, Brenna A / Ramirez, Kelsey / De Capite, Annette / Michener, William E / Werner, Allison Z / Klingeman, Dawn M / Schindel, Heidi S / Nelson, Robert / Foust, Lindsey / Guss, Adam M / Dale, Taraka / Johnson, Christopher W / Beckham, Gregg T

Metabolic engineering

2022 Volume 72, Page(s) 66–67

Language	English
Publishing date	2022-03-01
Publishing country	Belgium
Document type	Journal Article ; Published Erratum
ZDB-ID	1470383-x
ISSN	1096-7184 ; 1096-7176
ISSN (online)	1096-7184
ISSN	1096-7176
DOI	10.1016/j.ymben.2022.02.006
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6288: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Neoantigen-targeted CD8

Puig-Saus, Cristina / Sennino, Barbara / Peng, Songming / Wang, Clifford L / Pan, Zheng / Yuen, Benjamin / Purandare, Bhamini / An, Duo / Quach, Boi B / Nguyen, Diana / Xia, Huiming / Jilani, Sameeha / Shao, Kevin / McHugh, Claire / Greer, John / Peabody, Phillip / Nayak, Saparya / Hoover, Jonathan / Said, Sara /

Jacoby, Kyle / Dalmas, Olivier / Foy, Susan P / Conroy, Andrew / Yi, Michael C / Shieh, Christine / Lu, William / Heeringa, Katharine / Ma, Yan / Chizari, Shahab / Pilling, Melissa J / Ting, Marc / Tunuguntla, Ramya / Sandoval, Salemiz / Moot, Robert / Hunter, Theresa / Zhao, Sidi / Saco, Justin D / Perez-Garcilazo, Ivan / Medina, Egmidio / Vega-Crespo, Agustin / Baselga-Carretero, Ignacio / Abril-Rodriguez, Gabriel / Cherry, Grace / Wong, Deborah J / Hundal, Jasreet / Chmielowski, Bartosz / Speiser, Daniel E / Bethune, Michael T / Bao, Xiaoyan R / Gros, Alena / Griffith, Obi L / Griffith, Malachi / Heath, James R / Franzusoff, Alex / Mandl, Stefanie J / Ribas, Antoni

Nature

2023 Volume 615, Issue 7953, Page(s) 697–704

Abstract: Neoantigens are peptides derived from non-synonymous mutations presented by human leukocyte antigens (HLAs), which are recognized by antitumour T ... ...

Abstract	Neoantigens are peptides derived from non-synonymous mutations presented by human leukocyte antigens (HLAs), which are recognized by antitumour T cells
MeSH term(s)	Humans ; Antigens, Neoplasm/immunology ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/metabolism ; Immunotherapy ; Melanoma/drug therapy ; Melanoma/genetics ; Melanoma/immunology ; Melanoma/pathology ; Receptors, Antigen, T-Cell/immunology ; Receptors, Antigen, T-Cell/metabolism ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Inhibitors/therapeutic use ; HLA Antigens/immunology ; Neoplasm Metastasis ; Precision Medicine ; Gene Editing ; CRISPR-Cas Systems ; Mutation
Chemical Substances	Antigens, Neoplasm ; Receptors, Antigen, T-Cell ; Immune Checkpoint Inhibitors ; HLA Antigens ; PDCD1 protein, human
Language	English
Publishing date	2023-03-08
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	120714-3
ISSN	1476-4687 ; 0028-0836
ISSN (online)	1476-4687
ISSN	0028-0836
DOI	10.1038/s41586-023-05787-1
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 26: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MG 9: Show issues
Zs.MO 244: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: The American Board of Orthopaedic Surgery Response to COVID-19.

The Journal of the American Academy of Orthopaedic Surgeons

2020 Volume 28, Issue 11, Page(s) e465–e468

Abstract: The COVID-19 pandemic has disrupted every aspect of society in a way never previously experienced by our nation's orthopaedic surgeons. In response to the challenges the American Board of Orthopaedic Surgery has taken steps to adapt our Board ... ...

Abstract	The COVID-19 pandemic has disrupted every aspect of society in a way never previously experienced by our nation's orthopaedic surgeons. In response to the challenges the American Board of Orthopaedic Surgery has taken steps to adapt our Board Certification and Continuous Certification processes. These changes were made to provide flexibility for as many Candidates and Diplomates as possible to participate while maintaining our high standards. The American Board of Orthopaedic Surgery is first and foremost committed to the safety and well-being of our patients, physicians, and families while striving to remain responsive to the changing circumstances affecting our Candidates and Diplomates.
MeSH term(s)	COVID-19 ; Clinical Competence/standards ; Communicable Disease Control/methods ; Coronavirus Infections ; Education, Medical, Continuing/standards ; Education, Medical, Graduate/standards ; Female ; Humans ; Male ; Occupational Health ; Orthopedic Procedures/education ; Pandemics/prevention & control ; Pandemics/statistics & numerical data ; Patient Safety ; Pneumonia, Viral ; Safety Management ; Specialty Boards/standards ; United States
Keywords	covid19
Language	English
Publishing date	2020-04-23
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1200524-1
ISSN	1940-5480 ; 1067-151X
ISSN (online)	1940-5480
ISSN	1067-151X
DOI	10.5435/JAAOS-D-20-00392
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4048: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 274: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Engineering glucose metabolism for enhanced muconic acid production in Pseudomonas putida KT2440.

Metabolic engineering

2020 Volume 59, Page(s) 64–75

Abstract: Pseudomonas putida KT2440 has received increasing attention as an important biocatalyst for the conversion of diverse carbon sources to multiple products, including the olefinic diacid, cis,cis-muconic acid (muconate). P. putida has been previously ... ...

Abstract	Pseudomonas putida KT2440 has received increasing attention as an important biocatalyst for the conversion of diverse carbon sources to multiple products, including the olefinic diacid, cis,cis-muconic acid (muconate). P. putida has been previously engineered to produce muconate from glucose; however, periplasmic oxidation of glucose causes substantial 2-ketogluconate accumulation, reducing product yield and selectivity. Deletion of the glucose dehydrogenase gene (gcd) prevents 2-ketogluconate accumulation, but dramatically slows growth and muconate production. In this work, we employed adaptive laboratory evolution to improve muconate production in strains incapable of producing 2-ketogluconate. Growth-based selection improved growth, but reduced muconate titer. A new muconate-responsive biosensor was therefore developed to enable muconate-based screening using fluorescence activated cell sorting. Sorted clones demonstrated both improved growth and muconate production. Mutations identified by whole genome resequencing of these isolates indicated that glucose metabolism may be dysregulated in strains lacking gcd. Using this information, we used targeted engineering to recapitulate improvements achieved by evolution. Deletion of the transcriptional repressor gene hexR improved strain growth and increased the muconate production rate, and the impact of this deletion was investigated using transcriptomics. The genes gntZ and gacS were also disrupted in several evolved clones, and deletion of these genes further improved strain growth and muconate production. Together, these targets provide a suite of modifications that improve glucose conversion to muconate by P. putida in the context of gcd deletion. Prior to this work, our engineered strain lacking gcd generated 7.0 g/L muconate at a productivity of 0.07 g/L/h and a 38% yield (mol/mol) in a fed-batch bioreactor. Here, the resulting strain with the deletion of hexR, gntZ, and gacS achieved 22.0 g/L at 0.21 g/L/h and a 35.6% yield (mol/mol) from glucose in similar conditions. These strategies enabled enhanced muconic acid production and may also improve production of other target molecules from glucose in P. putida.
MeSH term(s)	Glucose/metabolism ; Metabolic Engineering ; Pseudomonas putida/genetics ; Pseudomonas putida/metabolism ; Sorbic Acid/analogs & derivatives ; Sorbic Acid/metabolism
Chemical Substances	muconic acid (3KD92ZL2KH) ; Glucose (IY9XDZ35W2) ; Sorbic Acid (X045WJ989B)
Language	English
Publishing date	2020-01-10
Publishing country	Belgium
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	1470383-x
ISSN	1096-7184 ; 1096-7176
ISSN (online)	1096-7184
ISSN	1096-7176
DOI	10.1016/j.ymben.2020.01.001
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6288: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Development of the KOOS

The American journal of sports medicine

2018 Volume 46, Issue 12, Page(s) 2915–2921

Abstract: ... Joint Replacement (KOOS, JR) is a validated short-form instrument to assess patient-reported outcomes ... JR with additional KOOS items would allow for the creation of a short-form KOOS-based global knee ... to those of the IKDC.: Hypothesis: An augmented version of the KOOS, JR could be created that would demonstrate ...

Abstract	Background: The Knee injury and Osteoarthritis Outcome Score (KOOS) has demonstrated inferior psychometric properties when compared with the International Knee Documentation Committee (IKDC) subjective knee form when assessing outcomes after anterior cruciate ligament (ACL) reconstruction. The KOOS, Joint Replacement (KOOS, JR) is a validated short-form instrument to assess patient-reported outcomes (PROs) after knee arthroplasty, and the purpose of this study was to determine if augmenting the KOOS, JR with additional KOOS items would allow for the creation of a short-form KOOS-based global knee score for patients undergoing ACL reconstruction, with psychometric properties similar to those of the IKDC. Hypothesis: An augmented version of the KOOS, JR could be created that would demonstrate convergent validity with the IKDC but avoid the ceiling effects and limitations previously noted with several of the KOOS subscales. Study design: Cohort study (diagnosis); Level of evidence, 2. Methods: Based on preoperative and 2-year postoperative responses to the KOOS questionnaires from a sample of 1904 patients undergoing ACL reconstruction, an aggregate score combining the KOOS, JR and the 4 KOOS Quality of Life subscale questions, termed the KOOS Results: The newly developed KOOS Conclusion: The large ceiling effects limit the ability to use several of the KOOS subscales with the younger, more active ACL population. However, by creating an aggregate score from the KOOS, JR and 4 KOOS Quality of Life subscale questions, the 11-item KOOS
MeSH term(s)	Adult ; Anterior Cruciate Ligament Injuries/physiopathology ; Anterior Cruciate Ligament Injuries/surgery ; Anterior Cruciate Ligament Reconstruction/adverse effects ; Cohort Studies ; Disability Evaluation ; Female ; Humans ; Male ; Patient Reported Outcome Measures ; Program Development ; Surveys and Questionnaires
Language	English
Publishing date	2018-08-03
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	197482-8
ISSN	1552-3365 ; 0363-5465
ISSN (online)	1552-3365
ISSN	0363-5465
DOI	10.1177/0363546518789619
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.B 1910: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Seagrass Abundance Predicts Surficial Soil Organic Carbon Stocks Across the Range of Thalassia testudinum in the Western North Atlantic

Fourqurean, James W. / Campbell, Justin E. / Rhoades, O.K. / Munson, Calvin J. / Krause, Johannes R. / Altieri, Andrew H. / Douglass, James G. / Heck, Kenneth L. / Paul, Valerie J. / Armitage, Anna R. / Barry, Savanna C. / Bethel, Enrique / Christ, Lindsey / Christianen, Marjolijn J.A. / Dodillet, Grace / Dutton, Katrina / Frazer, Thomas K. / Gaffey, Bethany M. / Glazner, Rachael /

Goeke, Janelle A. / Grana-Valdes, Rancel / Kramer, Olivier A.A. / Linhardt, Samantha T. / Martin, Charles W. / López, Isis Gabriela Martínez / McDonald, Ashley M. / Main, Vivienne A. / Manuel, Sarah A. / Marco-Méndez, Candela / O’Brien, Duncan A. / O’Shea, Owen / Patrick, Christopher J. / Peabody, Clare / Reynolds, Laura K. / Rodriguez, Alex / Rodriguez Bravo, Lucia M. / Sang, Amanda / Sawall, Yvonne / Smulders, Fee O.H. / Thompson, Jamie E. / van Tussenbroek, Brigitta / Wied, William L. / Wilson, Sara S.

Estuaries and coasts

2023 Volume 46, Issue 5

Abstract: The organic carbon (Corg) stored in seagrass meadows is globally significant and could be relevant in strategies to mitigate increasing CO2 concentration in the atmosphere. Most of that stored Corg is in the soils that underlie the seagrasses. We ... ...

Abstract	The organic carbon (Corg) stored in seagrass meadows is globally significant and could be relevant in strategies to mitigate increasing CO2 concentration in the atmosphere. Most of that stored Corg is in the soils that underlie the seagrasses. We explored how seagrass and soil characteristics vary among seagrass meadows across the geographic range of turtlegrass (Thalassia testudinum) with a goal of illuminating the processes controlling soil organic carbon (Corg) storage spanning 23° of latitude. Seagrass abundance (percent cover, biomass, and canopy height) varied by over an order of magnitude across sites, and we found high variability in soil characteristics, with Corg ranging from 0.08 to 12.59% dry weight. Seagrass abundance was a good predictor of the Corg stocks in surficial soils, and the relative importance of seagrass-derived soil Corg increased as abundance increased. These relationships suggest that first-order estimates of surficial soil Corg stocks can be made by measuring seagrass abundance and applying a linear transfer function. The relative availability of the nutrients N and P to support plant growth was also correlated with soil Corg stocks. Stocks were lower at N-limited sites than at P-limited ones, but the importance of seagrass-derived organic matter to soil Corg stocks was not a function of nutrient limitation status. This finding seemed at odds with our observation that labile standard substrates decomposed more slowly at N-limited than at P-limited sites, since even though decomposition rates were 55% lower at N-limited sites, less Corg was accumulating in the soils. The dependence of Corg stocks and decomposition rates on nutrient availability suggests that eutrophication is likely to exert a strong influence on carbon storage in seagrass meadows.
Keywords	Blue carbon ; Decomposition ; Latitudinal gradients ; Nutrient limitation ; Sediment ; Submerged aquatic vegetation
Subject code	550
Language	English
Publishing country	nl
Document type	Article ; Online
ZDB-ID	2229170-2
ISSN	1559-2731 ; 1559-2723
ISSN (online)	1559-2731
ISSN	1559-2723
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Order via subito

Details ▾
- Full text online
- Order with fees

Article: The American Board of Orthopaedic Surgery Response to COVID-19

J Am Acad Orthop Surg

Abstract	The COVID-19 pandemic has disrupted every aspect of society in a way never previously experienced by our nation's orthopaedic surgeons. In response to the challenges the American Board of Orthopaedic Surgery has taken steps to adapt our Board Certification and Continuous Certification processes. These changes were made to provide flexibility for as many Candidates and Diplomates as possible to participate while maintaining our high standards. The American Board of Orthopaedic Surgery is first and foremost committed to the safety and well-being of our patients, physicians, and families while striving to remain responsive to the changing circumstances affecting our Candidates and Diplomates.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #32324709
Database	COVID19

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: The American Board of Orthopaedic Surgery Response to COVID-19

Journal of the American Academy of Orthopaedic Surgeons

2020 Volume 28, Issue 11, Page(s) e465–e468

Keywords	Surgery ; Orthopedics and Sports Medicine ; covid19
Language	English
Publisher	Ovid Technologies (Wolters Kluwer Health)
Publishing country	us
Document type	Article ; Online
ZDB-ID	1200524-1
ISSN	1940-5480 ; 1067-151X
ISSN (online)	1940-5480
ISSN	1067-151X
DOI	10.5435/jaaos-d-20-00392
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

In stock of ZB MED Cologne/Königswinter

Zs.A 4048: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 274: Show issues

Order via subito

Details ▾

To top

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito