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  1. Article: The Associations of Body Mass Index, Body Image, Perceived Stress, and Mental Health among Female Nursing Students: A Cross-Sectional Study in Taiwan.

    Huang, Ching-Feng / Chou, Fan-Hao / Chang, Chia-Hao / Guo, Su-Er

    Healthcare (Basel, Switzerland)

    2023  Volume 11, Issue 17

    Abstract: Maintaining a healthy caloric intake and expenditure balance is challenging. The preliminary study examined (a) the associations of Body Mass Index (BMI), body image, perceived stress, mental health, dietary habits, and exercise participation among 310 ... ...

    Abstract Maintaining a healthy caloric intake and expenditure balance is challenging. The preliminary study examined (a) the associations of Body Mass Index (BMI), body image, perceived stress, mental health, dietary habits, and exercise participation among 310 female college nursing students and (b) the differences in these factors among BMI subgroups. The cutoffs for underweight, normal weight, overweight, and obesity were <18.5 kg/m
    Language English
    Publishing date 2023-08-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare11172426
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  2. Article ; Online: Co-Incidence of Intussusception and Appendicitis in a 10-Month-Old Infant.

    Huang, Chih-Kang / Song, Shih-Hsi / Wu, Tzee-Chung / Liu, Chin-Su / Huang, Ching-Feng

    Clinical pediatrics

    2023  , Page(s) 99228231221338

    Language English
    Publishing date 2023-12-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207678-0
    ISSN 1938-2707 ; 0009-9228
    ISSN (online) 1938-2707
    ISSN 0009-9228
    DOI 10.1177/00099228231221338
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  3. Article: Effects of coffee intake on airway hypersensitivity and immunomodulation: an

    Wong, Ying-Chi / Hsu, Wen-Cheng / Wu, Tzee-Chung / Huang, Ching-Feng

    Nutrition research and practice

    2023  Volume 17, Issue 4, Page(s) 631–640

    Abstract: Background/objectives: Coffee is a complex chemical mixture, with caffeine being the most well-known bioactive substance. The immunomodulatory and anti-inflammatory properties of coffee and caffeine impact health in various aspects, including the ... ...

    Abstract Background/objectives: Coffee is a complex chemical mixture, with caffeine being the most well-known bioactive substance. The immunomodulatory and anti-inflammatory properties of coffee and caffeine impact health in various aspects, including the respiratory system. The objective is to investigate the effects of coffee and caffeine on airway hyperresponsiveness and allergic reactions, as well as to analyze and compare associated cytokine profiles.
    Materials/methods: BALB/c mice were intraperitoneally sensitized with ovalbumin (OVA) and given OVA inhalation to induce airway hypersensitivity. Two weeks after sensitization, they were intragastrically gavaged with coffee or caffeine, both containing 0.3125 mg caffeine, daily for 4 weeks. Control mice were fed with double-distilled water. Serum OVA-specific antibody levels were measured beforehand and 5 weeks after the first gavage. Airway hyperresponsiveness was detected by whole body plethysmography after gavage. Cytokine levels of bronchoalveolar lavage and cultured splenocytes were analyzed.
    Results: Coffee effectively suppressed T helper 2-mediated specific antibody response. Airway responsiveness was reduced in mice treated with either coffee or caffeine. Compared to the control, coffee significantly reduced OVA-specific immunoglobulin (Ig) G, IgG1 and IgE antibody responses (
    Conclusions: Coffee effectively attenuated airway hyperresponsiveness and systemic allergic responses induced by OVA food allergen in mice. As a complex composition of bioactive substances, coffee displayed enhanced immunomodulatory and anti-inflammatory effects than caffeine.
    Language English
    Publishing date 2023-04-07
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2387946-4
    ISSN 2005-6168 ; 1976-1457
    ISSN (online) 2005-6168
    ISSN 1976-1457
    DOI 10.4162/nrp.2023.17.4.631
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  4. Article ; Online: Correlation of hepatic transient elastography measurements and abdominal adiposity in children: A cross-sectional study.

    Lee, Yii-Shiuan / Song, Shih-Hsi / Wu, Tzee-Chung / Wu, Shang-Liang / Huang, Ching-Feng

    Pediatrics and neonatology

    2023  Volume 64, Issue 6, Page(s) 631–636

    Abstract: Background: Transient elastography is a non-invasive assessment of steatosis (measured as the controlled attenuation parameter, [CAP]) and fibrosis (measured as liver stiffness measurement, [LSM]) in patients with pediatric non-alcoholic fatty liver ... ...

    Abstract Background: Transient elastography is a non-invasive assessment of steatosis (measured as the controlled attenuation parameter, [CAP]) and fibrosis (measured as liver stiffness measurement, [LSM]) in patients with pediatric non-alcoholic fatty liver disease (NAFLD). Abdominal adiposity is considered the most important factor for metabolic dysregulation including NAFLD. However, there is lack of a correlation between transient elastography measurements and abdominal adiposity. Accordingly, this study aimed to assess the correlation between transient elastography measurements and abdominal adiposity in children.
    Methods: This cross-sectional study included 137 children who visited the Taipei Veterans General Hospital. Hepatic steatosis (CAP) and fibrosis (LSM), were assessed by transient elastography. Abdominal adiposity including subcutaneous adipose tissue (SAT), visceral adipose tissue (VAT), and preperitoneal adipose tissue (PPT) was assessed using abdominal sonography. The correlation between transient elastography measurements and abdominal adiposity was assessed using multiple linear regression.
    Results: In total, 137 children were included in this study. SAT and VAT were significantly associated with CAP, whereas SAT was significantly associated with LSM. An increment of 1 mm in SAT increased CAP and LSM by 5.56 dB/m and 0.06 kPa, respectively.
    Conclusion: Certain abdominal adiposities, especially SAT, are significantly associated with CAP and LSM, as determined by transient elastography. Simple abdominal adiposity measured using sonography may be useful for the early detection of pediatric NAFLD.
    MeSH term(s) Humans ; Child ; Non-alcoholic Fatty Liver Disease/diagnostic imaging ; Non-alcoholic Fatty Liver Disease/complications ; Elasticity Imaging Techniques ; Cross-Sectional Studies ; Liver Cirrhosis/complications ; Liver Cirrhosis/diagnosis ; Liver Cirrhosis/pathology ; Adiposity ; Liver/diagnostic imaging ; Liver/pathology
    Language English
    Publishing date 2023-03-15
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2441816-X
    ISSN 2212-1692 ; 1875-9572
    ISSN (online) 2212-1692
    ISSN 1875-9572
    DOI 10.1016/j.pedneo.2022.12.018
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  5. Article ; Online: Bronchiolitis and Potential Pathophysiological Implications in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome Patients With Near-Normal Respiratory Compliance.

    Huang, Ching-Feng / Sun, Pei-Ting / Tay, Chee Kiang

    Critical care medicine

    2020  Volume 48, Issue 10, Page(s) e993–e994

    MeSH term(s) Betacoronavirus ; Bronchiolitis ; COVID-19 ; Coronavirus ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; Respiratory Distress Syndrome ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-02-12
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000004470
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  6. Article: Comparison of EMG amplitudes recorded by ipsilateral and contralateral electrodes placement during using trans-thyroid cartilage recording method in thyroid surgery.

    Chiang, Feng-Yu / Shih, Yu-Chen / Lien, Ching-Feng / Wang, Chih-Chun / Wang, Chien-Chung / Hwang, Tzer-Zen / Huang, Yaw-Chang / Wu, Che-Wei / Yeh, Tai-Hung / Huang, Tzu-Yen

    Frontiers in endocrinology

    2024  Volume 14, Page(s) 1305629

    Abstract: Objectives: The feasibility and reliability of trans-thyroid cartilage EMG recording method (TCERM) during intraoperative monitoring (IONM) of the recurrent laryngeal nerve (RLN) in thyroid surgery have been established. This study compared two ... ...

    Abstract Objectives: The feasibility and reliability of trans-thyroid cartilage EMG recording method (TCERM) during intraoperative monitoring (IONM) of the recurrent laryngeal nerve (RLN) in thyroid surgery have been established. This study compared two different recording electrode placements on the ipsi-lateral and contra-lateral lamina of the thyroid cartilage (TC).
    Methods: Fifty consecutive patients undergoing total thyroidectomy with 100 RLNs at risk were enrolled. Two paired subdermal needle electrodes were inserted into the subperichondrium of the bilateral TC lamina to record electromyography (EMG) signals. The channel leads from the TC electrodes were connected to the patient interface with two different modes. In A-mode, the electrode leads were placed ipsi-laterally, and channel 1 monitored the left RLN and channel 2 monitored the right RLN respectively. In B-mode, the electrode leads were placed contra-laterally, and channels 1 and 2 simultaneously monitored the same side of the RLN. The amplitudes of four EMG signals (V
    Results: All EMG amplitudes of V
    Conclusion: During using TCERM in thyroid surgery, the recording electrodes should be placed contra-laterally on the TC lamina. This approach ensures high and stable EMG signals, which are important for high-quality IONM of the RLN.
    MeSH term(s) Aged ; Humans ; Male ; Electrodes ; Reproducibility of Results ; Thyroid Cartilage/innervation ; Thyroid Gland/surgery ; Thyroidectomy/adverse effects ; Thyroidectomy/methods
    Language English
    Publishing date 2024-01-16
    Publishing country Switzerland
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1305629
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  7. Article ; Online: A High-Sodium Diet Modulates the Immune Response of Food Allergy in a Murine Model.

    Liu, Zheying / Li, Shih-Kuan / Huang, Chih-Kang / Huang, Ching-Feng

    Nutrients

    2021  Volume 13, Issue 11

    Abstract: Mounting evidence demonstrates that a high-salt diet (HSD) not only affects hemodynamic changes but also disrupts immune homeostasis. The T helper 17 (Th17) and regulatory T cells (Tregs) are susceptible to hypersalinity. However, research on the ... ...

    Abstract Mounting evidence demonstrates that a high-salt diet (HSD) not only affects hemodynamic changes but also disrupts immune homeostasis. The T helper 17 (Th17) and regulatory T cells (Tregs) are susceptible to hypersalinity. However, research on the influence of sodium on Th2-mediated food allergies remains scarce. We aimed to investigate the effect of dietary sodium on the immune response to food allergies. Mice maintained on an HSD (4% NaCl), low-salt diet (LSD; 0.4% NaCl), or control diet (CTRL; 1.0% NaCl) were orally sensitized with ovalbumin (OVA) and a cholera toxin (CT) adjuvant, and then subjected to an intragastric OVA challenge. OVA-specific immunoglobulin G (IgG), IgG1, IgG2a, and IgE antibodies were significantly higher in the HSD group than in the CTRL group (
    MeSH term(s) Animal Nutritional Physiological Phenomena/immunology ; Animals ; Diet/adverse effects ; Diet/methods ; Diet, Sodium-Restricted/methods ; Disease Models, Animal ; Food Hypersensitivity/etiology ; Food Hypersensitivity/immunology ; Immunity ; Mice ; Ovalbumin/immunology ; Salt Tolerance/immunology ; Sodium, Dietary/administration & dosage ; Sodium, Dietary/immunology ; T-Lymphocytes, Regulatory/immunology ; Th2 Cells/immunology
    Chemical Substances Sodium, Dietary ; Ovalbumin (9006-59-1)
    Language English
    Publishing date 2021-10-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu13113684
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  8. Article ; Online: Prevalence, clinical presentation, and associated atopic diseases of pediatric fruit and vegetable allergy: A population-based study.

    Li, Shih-Kuan / Liu, Zheying / Huang, Chih-Kang / Wu, Tzee-Chung / Huang, Ching-Feng

    Pediatrics and neonatology

    2022  Volume 63, Issue 5, Page(s) 520–526

    Abstract: Background: In children, fruit and vegetable allergies are often overlooked compared with well-known allergies such as those to eggs, milk, and shellfish. Therefore, this study aimed to analyze fruit and vegetable allergies in children, including ... ...

    Abstract Background: In children, fruit and vegetable allergies are often overlooked compared with well-known allergies such as those to eggs, milk, and shellfish. Therefore, this study aimed to analyze fruit and vegetable allergies in children, including prevalence, types of food allergens, clinical presentation, management, and associated comorbid atopic diseases.
    Methods: In 2012, a nationwide, cross-sectional, random sampling questionnaire-based survey for common fruit and vegetable allergies was conducted in Taiwan. Information regarding these plant food allergies was collected. Physicians diagnosed food allergies according to the descriptions of convincing symptoms. Enrolled questionnaires were reviewed by expert pediatricians.
    Results: A total of 9,982 valid questionnaires were analyzed. The overall prevalence of fruit and vegetable allergies was 5.6% (n = 560) and 3.0% (n = 304), respectively. The most common fruit allergen was mango, followed by kiwifruit, whereas taro and bamboo shoot were the most common vegetable allergens. Meanwhile, most allergic symptoms were of the mucocutaneous tissue, followed by the upper airway and gastrointestinal tract. Most only required avoidance of allergens and not medical treatment. Children with fruit or vegetable allergies had a higher percentage of comorbid atopic dermatitis, allergic rhinitis, and asthma than those without food allergies; additionally, the proportion of comorbid atopic diseases was similar between fruit and vegetable allergies and shellfish allergy. One child developed anaphylaxis due to a corn allergy.
    Conclusions: Fruits and vegetables are common food allergens in Taiwanese children who present with diverse and potentially severe symptoms. Children with plant food allergies had a percentage of comorbid atopic diseases similar to that of shellfish allergy, the most common allergen. These findings indicate the importance of considering fruit and vegetable allergies in children.
    MeSH term(s) Allergens ; Child ; Cross-Sectional Studies ; Food Hypersensitivity/diagnosis ; Food Hypersensitivity/epidemiology ; Food Hypersensitivity/therapy ; Fruit ; Humans ; Prevalence ; Shellfish Hypersensitivity ; Vegetables
    Chemical Substances Allergens
    Language English
    Publishing date 2022-06-22
    Publishing country Singapore
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2441816-X
    ISSN 2212-1692 ; 1875-9572
    ISSN (online) 2212-1692
    ISSN 1875-9572
    DOI 10.1016/j.pedneo.2022.03.019
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  9. Article ; Online: Nature of the work correlated to overweight and obesity for nurses: A 10-year hospital-based cohort study.

    Huang, Chih-Kang / Huang, Ching-Feng / Liu, Zheying / Li, Shih-Kuan / Chiu, Yu-Hua / Chiu, Hsiao-Hui / Wu, Shang-Liang

    Journal of the Chinese Medical Association : JCMA

    2023  Volume 86, Issue 10, Page(s) 940–944

    Abstract: Background: Nurses are a high-risk group for overweight and obesity due to high stress, low-labor medical work, irregular diet, and lack of exercise. There is scarce information on relationship between job characteristics and overweight and obesity ... ...

    Abstract Background: Nurses are a high-risk group for overweight and obesity due to high stress, low-labor medical work, irregular diet, and lack of exercise. There is scarce information on relationship between job characteristics and overweight and obesity among nurses. This study aimed to answer the question. Does the nature of the work including job position, seniority relate to overweight and obesity among nurses? Their incidence was also investigated.
    Methods: We conducted a retrospective cohort study of nurses who underwent annual checkups during 2007 to 2016 in a medical center. Overweight was defined as a body mass index between 24 and 27 kg/m 2 . Obesity was defined as a body mass index higher than 27 kg/m 2 . We calculated the prevalence and incidence of overweight and obesity and estimated relative risks using logistic regression.
    Results: Overall, 4253 participants were enrolled for the incidence of overweight and obesity. We found that junior staff, administrative directors, working in intensive care units, and old age had a high possibility of overweight. Junior staff, administrative directors, old age, and male sex tend to be obesity. Overweight and obesity occurred rapidly in the first 2 years of their career.
    Conclusion: Our findings suggest that policies should be set up to achieve the goal of workplace health promotion. Health plans focusing on these factors may help nurses avoid obesity and overweight. The director of the hospital should keep track of the health checkup database to confirm the benefits of its long-term implementation.
    MeSH term(s) Humans ; Male ; Overweight/epidemiology ; Overweight/etiology ; Cohort Studies ; Retrospective Studies ; Obesity/epidemiology ; Body Mass Index ; Hospitals
    Language English
    Publishing date 2023-08-22
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2107283-8
    ISSN 1728-7731 ; 1726-4901
    ISSN (online) 1728-7731
    ISSN 1726-4901
    DOI 10.1097/JCMA.0000000000000983
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  10. Article ; Online: Pediatric non-alcoholic fatty liver disease predicted by anthropometric values through transient elastography.

    Song, Shih-Hsi / Wong, Ying-Chi / Wu, Tzee-Chung / Huang, Ching-Feng

    Pediatrics international : official journal of the Japan Pediatric Society

    2021  Volume 63, Issue 2, Page(s) 183–188

    Abstract: Background: Non-alcoholic fatty liver disease (NAFLD) is the leading cause of pediatric chronic liver disease, which is strongly associated with obesity. Transient elastography, together with anthropometric values including waist-to-height ratio (WHtR) ... ...

    Abstract Background: Non-alcoholic fatty liver disease (NAFLD) is the leading cause of pediatric chronic liver disease, which is strongly associated with obesity. Transient elastography, together with anthropometric values including waist-to-height ratio (WHtR) and body mass index (BMI) z-scores are a more precise diagnostic method of NAFLD than ultrasonography. Through transient elastography, we investigate the principal anthropometric values associated with pediatric NAFLD.
    Methods: Healthy children between the ages of 6-18 years whose BMIs were ≥85% of normal were recruited as the overweight-and-obese group, and children whose BMIs ranged between 5%-85% were recruited as the control group. Non-alcoholic fatty liver disease was evaluated via transient elastography. BMI z-score and WHtR were measured.
    Results: A total of 107 (58 overweight-and-obese, 49 control) children were recruited. As evaluated by transient elastography, children in the overweight-and-obese group had significantly higher controlled attenuation parameter and liver stiffness measurement values than the control group. To detect fatty liver, WHtR with a cut-off point of 0.481 and BMI z-score with cut-off point of 1.075 had the best sensitivity and specificity. To identify liver stiffness or inflammation, WHtR with cut-off point of 0.514 and BMI z-score with cut-off point of 1.62 had the best sensitivity and specificity. Controlled attenuation parameter demonstrated a fair correlation with WHtR and BMI z-scores, even in the normal range of these parameters.
    Conclusions: Transient elastography together with anthropometric measurements demonstrate that pediatric NAFLD may develop earlier than expected. We present principal anthropometric values associated with pediatric NAFLD.
    MeSH term(s) Adolescent ; Anthropometry ; Body Mass Index ; Child ; Elasticity Imaging Techniques ; Humans ; Liver/diagnostic imaging ; Non-alcoholic Fatty Liver Disease/diagnostic imaging ; Ultrasonography
    Language English
    Publishing date 2021-02-15
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1470376-2
    ISSN 1442-200X ; 1328-8067
    ISSN (online) 1442-200X
    ISSN 1328-8067
    DOI 10.1111/ped.14395
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