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Article ; Online: Exercise-induced ventricular tachycardia in a case with hypertrophic cardiomyopathy taking cibenzoline.

Shiohira, Shinya / Kawabata, Mihoko / Goya, Masahiko / Maeda, Shingo / Sasano, Tetsuo / Hirao, Kenzo

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc

2020 Volume 26, Issue 1, Page(s) e12789

Abstract: We report a 17-year-old woman with hypertrophic cardiomyopathy (HCM) successfully resuscitated from ventricular fibrillation while taking cibenzoline. During exercise-stress testing before implanting an implantable cardioverter-defibrillator, ventricular ...

Abstract	We report a 17-year-old woman with hypertrophic cardiomyopathy (HCM) successfully resuscitated from ventricular fibrillation while taking cibenzoline. During exercise-stress testing before implanting an implantable cardioverter-defibrillator, ventricular tachycardia was induced and thought to be a proarrhythmia due to the use-dependent effect of the Na channel blockade with cibenzoline. In patients with arrhythmogenic substrates such as HCM, it is critical to pay attention to the proarrhythmic effects of class I antiarrhythmic drugs while increasing heart rate.
MeSH term(s)	Adolescent ; Anti-Arrhythmia Agents/therapeutic use ; Cardiomyopathy, Hypertrophic/complications ; Cardiopulmonary Resuscitation/methods ; Exercise ; Exercise Test/adverse effects ; Female ; Humans ; Imidazoles/therapeutic use ; Sotalol/therapeutic use ; Tachycardia, Ventricular/complications ; Tachycardia, Ventricular/therapy ; Ventricular Fibrillation/complications ; Ventricular Fibrillation/drug therapy
Chemical Substances	Anti-Arrhythmia Agents ; Imidazoles ; Sotalol (A6D97U294I) ; cifenline (Z7489237QT)
Language	English
Publishing date	2020-08-19
Publishing country	United States
Document type	Case Reports
ZDB-ID	1325530-7
ISSN	1542-474X ; 1082-720X
ISSN (online)	1542-474X
ISSN	1082-720X
DOI	10.1111/anec.12789
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Zs.A 4953: Show issues

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Article ; Online: Comparative evaluation of standard maintenance-dose clopidogrel versus low-dose prasugrel in patients with stable coronary artery disease after percutaneous coronary intervention.

Akimaru, Kaoru / Iwabuchi, Masashi / Ishida, Akio / Uehara, Hiroki / Higa, Namio / Kakazu, Masanori / Wake, Minoru / Maeda, Taketoshi / Maeda, Toshiki / Arima, Hisatomi / Ohya, Yusuke / Tokashiki, Shinta / Wakugawa, Hayashi / Miyagi, Ayane / Shiohira, Shinya / Zaima, Satoshi / Shiohira, Tomohiro / Toma, Yuichirou / Ikemiyagi, Hidekazu

International journal of cardiology

2022 Volume 356, Page(s) 30–35

Abstract: Background: Treatment with low-dose prasugrel might be more beneficial even in chronic stable coronary artery disease (CAD) patients treated with clopidogrel. We compared platelet reactivity between standard maintenance-dose and low-dose prasugrel in ... ...

Abstract	Background: Treatment with low-dose prasugrel might be more beneficial even in chronic stable coronary artery disease (CAD) patients treated with clopidogrel. We compared platelet reactivity between standard maintenance-dose and low-dose prasugrel in stable CAD patients. Methods: This multicenter study enrolled 164 stable CAD patients receiving dual antiplatelet therapy with aspirin and clopidogrel. Patients were randomly assigned to continue treatment with 75-mg clopidogrel daily (n = 80) or switch to 3.75-mg prasugrel daily (n = 84). Platelet reactivity was evaluated by measuring P2Y Results: The PRU level was comparable between the two groups at baseline but was significantly lower in the prasugrel group than in the clopidogrel group on days 5 (133.0 vs. 156.8 PRU, P = 0.005) and 30 (124.3 vs. 158.0 PRU, P < 0.001). On day 30, the PRU level was lower in the prasugrel group among patients categorized as poor and intermediate metabolizers but not among extensive metabolizers. Conclusions: Low-dose prasugrel achieves more consistent antiplatelet effects than clopidogrel irrespective of the metabolic phenotype in Japanese patients with stable CAD. Low-dose prasugrel might be also beneficial in the chronic phase without increasing the bleeding risk among stable CAD patients in other countries.
MeSH term(s)	Clopidogrel ; Coronary Artery Disease/diagnosis ; Coronary Artery Disease/drug therapy ; Coronary Artery Disease/surgery ; Cytochrome P-450 CYP2C19/genetics ; Cytochrome P-450 CYP2C19/metabolism ; Humans ; Percutaneous Coronary Intervention/adverse effects ; Platelet Aggregation Inhibitors ; Prasugrel Hydrochloride/therapeutic use ; Treatment Outcome
Chemical Substances	Platelet Aggregation Inhibitors ; Clopidogrel (A74586SNO7) ; Cytochrome P-450 CYP2C19 (EC 1.14.14.1) ; Prasugrel Hydrochloride (G89JQ59I13)
Language	English
Publishing date	2022-02-19
Publishing country	Netherlands
Document type	Journal Article ; Multicenter Study ; Randomized Controlled Trial
ZDB-ID	779519-1
ISSN	1874-1754 ; 0167-5273
ISSN (online)	1874-1754
ISSN	0167-5273
DOI	10.1016/j.ijcard.2022.02.023
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Zs.A 1673: Show issues

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Article: Bronchogenic cyst of the atrioventricular septum presenting with ventricular fibrillation.

Shiohira, Shinya / Sasaki, Takeshi / Maeda, Shingo / Kawabata, Mihoko / Goya, Masahiko / Hirao, Kenzo

HeartRhythm case reports

2017 Volume 3, Issue 8, Page(s) 389–391

Language	English
Publishing date	2017-06-13
Publishing country	United States
Document type	Case Reports
ZDB-ID	2834871-0
ISSN	2214-0271
ISSN	2214-0271
DOI	10.1016/j.hrcr.2017.05.005
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Article: Right coronary artery wall edema provoked by cavotricuspid isthmus radiofrequency ablation.

Nishimura, Takuro / Goya, Masahiko / Shiohira, Shinya / Yoshitake, Takakatsu / Shirai, Yasuhiro / Maeda, Shingo / Sasaki, Takeshi / Kawabata, Mihoko / Sasano, Tetsuo / Hirao, Kenzo

HeartRhythm case reports

2017 Volume 3, Issue 9, Page(s) 443–446

Language	English
Publishing date	2017-07-18
Publishing country	United States
Document type	Case Reports
ZDB-ID	2834871-0
ISSN	2214-0271
ISSN	2214-0271
DOI	10.1016/j.hrcr.2017.07.010
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Article ; Online: Candidacy for a Subcutaneous Implantable Cardioverter Defibrillator in Patients with Cardiac Resynchronization Therapy.

Kawabata, Mihoko / Goya, Masahiko / Takahashi, Yoshihide / Maeda, Shingo / Yagishita, Atsuhiko / Shirai, Yasuhiro / Kaneko, Masakazu / Shiohira, Shinya / Hirao, Kenzo

International heart journal

2018 Volume 59, Issue 5, Page(s) 951–958

Abstract: In patients requiring an implantable cardioverter defibrillator (ICD), the combined use of a prior pacemaker and a subcutaneous ICD (S-ICD) could be an alternative treatment option to implantation of new leads or upgrading of pacemakers to an ICD if ... ...

Abstract	In patients requiring an implantable cardioverter defibrillator (ICD), the combined use of a prior pacemaker and a subcutaneous ICD (S-ICD) could be an alternative treatment option to implantation of new leads or upgrading of pacemakers to an ICD if vascular access is limited. Here, we assessed the prevalence of S-ICD's eligibility according to surface electrogram screening in those receiving cardiac resynchronization therapy (CRT). S-ICD's eligibility was assessed in patients with a CRT pacemaker or a CRT defibrillator using the S-ICD template screening tool. Eligibility was defined as fulfillment of the template in both supine and upright positions in one or more leads during biventricular pacing. Among 44 patients (34 men, age: 67 ± 12), 36 (82%) were found to be eligible. The T/QRS amplitude ratio in lead II was significantly lower in those who were eligible (0.31 ± 0.16 versus 0.44 ± 0.18 in the ineligible group, P = 0.04). The lead position, underlying disease, and other electrocardiographic findings were not different between those who were eligible and those who were not. The majority of patients with biventricular pacing were eligible for S-ICD based on current screening tests and may benefit from this treatment. Further study is required.
MeSH term(s)	Aged ; Cardiac Resynchronization Therapy/methods ; Combined Modality Therapy ; Defibrillators, Implantable/statistics & numerical data ; Defibrillators, Implantable/utilization ; Electrocardiography/instrumentation ; Eligibility Determination/standards ; Female ; Heart Failure/physiopathology ; Heart Failure/therapy ; Humans ; Male ; Mass Screening/methods ; Middle Aged ; Pacemaker, Artificial/statistics & numerical data ; Pacemaker, Artificial/utilization ; Prevalence ; Secondary Prevention/standards ; Subcutaneous Tissue ; Treatment Outcome
Language	English
Publishing date	2018-08-11
Publishing country	Japan
Document type	Journal Article
ZDB-ID	2187806-7
ISSN	1349-3299 ; 1349-2365
ISSN (online)	1349-3299
ISSN	1349-2365
DOI	10.1536/ihj.17-550
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Zs.A 211: Show issues

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Article ; Online: Left Atrial Appendage Thrombi Formation in Japanese Non-Valvular Atrial Fibrillation Patients During Anticoagulation Therapy　- Warfarin vs. Direct Oral Anticoagulants.

Kawabata, Mihoko / Goya, Masahiko / Sasaki, Takeshi / Maeda, Shingo / Shirai, Yasuhiro / Nishimura, Takuro / Yoshitake, Takakatsu / Shiohira, Shinya / Isobe, Mitsuaki / Hirao, Kenzo

Circulation journal : official journal of the Japanese Circulation Society

2017 Volume 81, Issue 5, Page(s) 645–651

Abstract: Background: Atrial fibrillation (AF) is a common cardiac arrhythmia, associated with increased cardiovascular morbidity and mortality including thromboembolic events. The aims of this study were to assess the prevalence of left atrial appendage (LAA) ... ...

Abstract	Background: Atrial fibrillation (AF) is a common cardiac arrhythmia, associated with increased cardiovascular morbidity and mortality including thromboembolic events. The aims of this study were to assess the prevalence of left atrial appendage (LAA) thrombi in Japanese non-valvular atrial fibrillation (NVAF) patients undergoing preprocedural transesophageal echocardiography (TEE) during anticoagulation therapy, and to compare the efficacy of warfarin and direct oral anticoagulants (DOAC).Methods and Results:This retrospective study reviewed records of 559 consecutive NVAF patients (445 men; age, 62±11 years) undergoing preprocedural TEE following at least 3 weeks of anticoagulation therapy. Of these, 275 patients had non-paroxysmal AF (49%). LAA thrombus was observed in 15 patients (2.7%). The prevalence of LAA thrombi was similar between the DOAC group (2.6%) and the warfarin group (2.8%, P=0.86). No patients with CHA Conclusions: LAA thrombi were found in 2.7% of Japanese NVAF patients scheduled for procedures despite ongoing oral anticoagulation therapy. Incidence of thrombi was similar for patients on DOAC and on warfarin.
Language	English
Publishing date	2017-04-25
Publishing country	Japan
Document type	Journal Article
ZDB-ID	2068090-9
ISSN	1347-4820 ; 1346-9843
ISSN (online)	1347-4820
ISSN	1346-9843
DOI	10.1253/circj.CJ-16-1089
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Ui IV Zs.74: Show issues

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Article ; Online: Surface Electrocardiogram Screening for Subcutaneous Implantable Cardioverter-Defibrillators in Japanese Patients With and Without Brugada Syndrome.

Kawabata, Mihoko / Goya, Masahiko / Sasaki, Takeshi / Maeda, Shingo / Yagishita, Atsuhiko / Shirai, Yasuhiro / Kaneko, Masakazu / Shiohira, Shinya / Isobe, Mitsuaki / Hirao, Kenzo

Circulation journal : official journal of the Japanese Circulation Society

2017 Volume 81, Issue 7, Page(s) 981–987

Abstract: Background: Subcutaneous implantable cardioverter-defibrillators (S-ICD) could eliminate lead-associated complications. We assessed the prevalence of S-ICD ineligibility in conventional ICD recipients and compared it in patients with and without Brugada ...

Abstract	Background: Subcutaneous implantable cardioverter-defibrillators (S-ICD) could eliminate lead-associated complications. We assessed the prevalence of S-ICD ineligibility in conventional ICD recipients and compared it in patients with and without Brugada syndrome (BrS).Methods and Results:Consecutive patients with a transvenous ICD without an indication for antibradycardia pacing were assessed. A patient was considered eligible for S-ICD if the ECG satisfied the screening template, both supine and standing, in ≥1 lead. Among 130 patients (103 men, age 57±15 years), a total of 18 (13.8%) patients were ineligible. The BrS group (n=33) had a significantly higher prevalence of S-ICD screening failure as compared with the non-BrS group (P=0.003; 30% vs. 8.2%). In the BrS group, the body mass index (BMI) was significantly lower, and T/QRS amplitude in lead I was significantly higher in those who were ineligible than that in the patients who were eligible. Of the 10 BrS patients failing the screening, 4 became eligible in the right parasternal electrode position. Conclusions: Among current ICD patients, there was a high incidence of patients with BrS who were unsuitable for S-ICD based on the left parasternal screening test. Suitability screening of patients for S-ICDs should be conducted carefully in patients with BrS, particularly if the BMI is low. Right parasternal electrode positioning should also be tested in such BrS patients.
Language	English
Publishing date	2017-06-23
Publishing country	Japan
Document type	Journal Article
ZDB-ID	2068090-9
ISSN	1347-4820 ; 1346-9843
ISSN (online)	1347-4820
ISSN	1346-9843
DOI	10.1253/circj.CJ-16-1295
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Article ; Online: Exertional syncope caused by myocardial ischemia due to arterial steal syndrome in left internal mammary artery graft.

Nakagama, Shun / Yonetsu, Taishi / Shiohira, Shinya / Matsuda, Yuji / Sasaoka, Taro / Hatano, Yu / Yagishita, Atsuhiko / Umemoto, Tomoyuki / Maeda, Shingo / Yamamoto, Takanobu / Yoneyama, Tomohiro / Kitazume, Yoshio / Takahashi, Yoshihide / Maejima, Yasuhiro / Kawabata, Mihoko / Goya, Masahiko / Ashikaga, Takashi / Arai, Hirokuni / Hirao, Kenzo

Coronary artery disease

2019 Volume 30, Issue 6, Page(s) 469–470

MeSH term(s)	Coronary Circulation ; Coronary-Subclavian Steal Syndrome/diagnostic imaging ; Coronary-Subclavian Steal Syndrome/etiology ; Coronary-Subclavian Steal Syndrome/physiopathology ; Coronary-Subclavian Steal Syndrome/therapy ; Hemodynamics ; Humans ; Internal Mammary-Coronary Artery Anastomosis/adverse effects ; Male ; Middle Aged ; Physical Exertion ; Recurrence ; Syncope/diagnosis ; Syncope/etiology ; Syncope/physiopathology ; Syncope/prevention & control ; Treatment Outcome
Language	English
Publishing date	2019-04-11
Publishing country	England
Document type	Case Reports
ZDB-ID	1047268-x
ISSN	1473-5830 ; 0954-6928
ISSN (online)	1473-5830
ISSN	0954-6928
DOI	10.1097/MCA.0000000000000729
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Zs.A 3039: Show issues

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Article ; Online: Safety and Efficacy of Transvenous Lead Extraction With a High-Frequency Excimer Laser　- A Single Center Experience.

Yoshitake, Takakatsu / Goya, Masahiko / Sasaki, Takeshi / Shiohira, Shinya / Sekigawa, Masahiro / Shirai, Yasuhiro / Lee, Kiko / Yagishita, Atsuhiko / Maeda, Shingo / Takahashi, Yoshihide / Kawabata, Mihoko / Hirao, Kenzo

Circulation journal : official journal of the Japanese Circulation Society

2018 Volume 82, Issue 12, Page(s) 2992–2997

Abstract: Background: Transvenous lead extractions have been performed using 40-Hz laser sheaths. Recently, a new 80-Hz laser sheath became available, but only a few reports have compared the effectiveness of the 40- and 80-Hz laser sheaths. Methods and Results: ... ...

Abstract	Background: Transvenous lead extractions have been performed using 40-Hz laser sheaths. Recently, a new 80-Hz laser sheath became available, but only a few reports have compared the effectiveness of the 40- and 80-Hz laser sheaths. Methods and Results: This study included 215 patients. Lead extractions using only laser sheaths were analyzed. The clinical characteristics, extraction parameters, and extraction tools were evaluated. The procedures were performed with 40-Hz sheaths in 150 patients (group 1: 270 leads) and 80-Hz sheaths in 65 (group 2: 99 leads). No statistically significant differences were observed in the clinical parameters except for sex. The mean implant duration was 95.3±86.0 and 78.2±56.8 months in groups 1 and 2, respectively (P=0.07). The respective mean laser time and number of laser pulses were 48.5±52.1 and 48.1±56.1 s (P=0.96) and 2,035.0±2,384.0 and 3,955.1±2,339.3 pulses (P<0.0001). Complete removal was achieved for 97.4% of the leads and in 98.0% in both groups (P=0.38). Major complications occurred in 2.0% and 3.1% of the patients in groups 1 and 2, respectively (P=0.94). Conclusions: Transvenous lead extraction using high-frequency laser sheaths was as highly successful as with low-frequency laser sheaths in Japanese patients.
MeSH term(s)	Aged ; Aged, 80 and over ; Defibrillators, Implantable/adverse effects ; Equipment Failure ; Female ; Humans ; Lasers, Excimer ; Male ; Middle Aged ; Pacemaker, Artificial/adverse effects
Language	English
Publishing date	2018-10-12
Publishing country	Japan
Document type	Clinical Trial ; Journal Article
ZDB-ID	2068090-9
ISSN	1347-4820 ; 1346-9843
ISSN (online)	1347-4820
ISSN	1346-9843
DOI	10.1253/circj.CJ-18-0869
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Article ; Online: Transvenous extraction of advisory implantable cardioverter defibrillator leads with a relatively long implant duration.

Goya, Masahiko / Nagashima, Michio / Hiroshima, Ken-Ichi / Hayashi, Kentaro / Makihara, Yu / Fukunaga, Masato / An, Yoshimori / Ohe, Masatsugu / Sasaki, Takeshi / Shiohira, Shinya / Shirai, Yasuhiro / Kawabata, Mihoko / Ando, Kenji / Isobe, Mitsuaki / Hirao, Kenzo

Journal of cardiology

2018 Volume 72, Issue 4, Page(s) 316–320

Abstract: Background: Optimal management of advisory implantable cardioverter defibrillator (ICD) leads has not been established. Several studies were reported concerning the lead extraction of advisory ICD leads, but the implant duration of those studies was ... ...

Abstract	Background: Optimal management of advisory implantable cardioverter defibrillator (ICD) leads has not been established. Several studies were reported concerning the lead extraction of advisory ICD leads, but the implant duration of those studies was short. We estimated the efficacy of lead extractions of advisory ICD leads with a relatively longer duration in Japanese patients. Methods: We retrospectively analyzed 28 patients who underwent a lead extraction at Kokura Memorial Hospital and Tokyo Medical and Dental University Hospital [Fidelis (Medtronic, Minneapolis, MN, USA): n=19, Riata (St. Jude Medical, Sylmar, CA, USA): n=8, Isoline (SORIN CRM SAS, Clamart, France): n=1]. The mean implant duration was 63.3±19.3 months. The indications were device related infections in 3, electrical lead failures in 18, electrical lead failures and venous obstructions in 3, and prophylactic reasons in 4 patients. Inappropriate shocks because of electrical lead failures were observed in 9 patients. Results: Complete removals were achieved of all 28 advisory leads. In 23 out of 28 patients, new ICD leads were implanted during the same procedure. In one patient, open chest surgery was performed for a hemothorax that occurred during a new ICD lead implantation just after successfully removing the advisory ICD lead. There were no other major or minor complications. Conclusion: Transvenous extractions of advisory ICD leads with relatively long implant duration were performed with a high success rate and low complication and mortality rate in Japanese patients.
MeSH term(s)	Aged ; Defibrillators, Implantable/adverse effects ; Device Removal/methods ; Female ; Humans ; Male ; Middle Aged ; Operative Time ; Retrospective Studies ; Time Factors ; Tokyo ; Treatment Outcome
Language	English
Publishing date	2018-04-25
Publishing country	Netherlands
Document type	Evaluation Studies ; Journal Article
ZDB-ID	639364-0
ISSN	1876-4738 ; 0386-2887 ; 0914-5087
ISSN (online)	1876-4738
ISSN	0386-2887 ; 0914-5087
DOI	10.1016/j.jjcc.2018.03.007
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