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Article: Procalcitonin and CRP as Biomarkers in Discrimination of Community-acquired Pneumonia and Exacerbation of COPD.

Çolak, Ayfer / Yılmaz, Celalettin / Toprak, Burak / Aktoğu, Serir

2017 Volume 36, Issue 2, Page(s) 122–126

Abstract: Background: Serum procalcitonin (PCT) and C-reactive protein (CRP) are markers of systemic inflammation and bacterial infection. We aimed to compare the usefulness of procalcitonin and CRP in patients with community-acquired pneumonia and exacerbations ... ...

Abstract	Background: Serum procalcitonin (PCT) and C-reactive protein (CRP) are markers of systemic inflammation and bacterial infection. We aimed to compare the usefulness of procalcitonin and CRP in patients with community-acquired pneumonia and exacerbations of chronic obstructive pulmonary disease (COPD). Methods: A total of 116 consecutive patients were included in the study: 76 with chronic obstructive pulmonary disease in group 1, and 40 with pneumonia in group 2. Results: Median serum CRP level was 44 mg/L in the COPD group and 132 mg/L in the pneumonia group. Median value of serum PCT was found to be 0.07 in the COPD group and 0.14 ng/mL in the pneumonia group. Serum PCT and CRP levels were significantly higher in the pneumonia group compared to the COPD group (p<0.001). The area under the ROC curve was 0.788 (CI: 0.704-0.872) for CRP and 0.699 (CI: 0.599-0.800) for procalcitonin to identify pneumonia. Conclusions: Procalcitonin and CRP levels were significantly higher in patients with community-acquired pneumonia presenting to the emergency department with indications for hospitalization than in patients with exacerbations of chronic obstructive pulmonary disease. Serum CRP and procalcitonin concentrations were strongly correlated. CRP might be a more valuable marker in these patients with lower respiratory tract infections.
Language	English
Publishing date	2017-04-22
Publishing country	Serbia
Document type	Journal Article
ZDB-ID	2387367-X
ISSN	1452-8258
ISSN	1452-8258
DOI	10.1515/jomb-2017-0011
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Zs.A 3112: Show issues

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Article: The diagnostic accuracy of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in mediastinal tuberculous lymphadenitis

Erer, Onur Fevzi / Erol, Serhat / Anar, Ceyda / Biçmen, Can / Aydoğdu, Zekiye / Aktoğu, Serir

Turkish journal of medical sciences

2017 Volume 47, Issue 6, Page(s) 1874–1879

Abstract: Background/aim: Mediastinal lymph nodes are the second most commonly affected lymph nodes in tuberculous lymphadenitis. It is often difficult to diagnose tuberculosis in patients with lymphadenopathy without parenchymal lesions. The aim of this study was ...

Abstract	Background/aim: Mediastinal lymph nodes are the second most commonly affected lymph nodes in tuberculous lymphadenitis. It is often difficult to diagnose tuberculosis in patients with lymphadenopathy without parenchymal lesions. The aim of this study was to describe the diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in patients with isolated mediastinal tuberculous lymphadenitis (MTLA). Materials and methods: This study included 527 patients who had undergone EBUS-TBNA between December 2012 and December 2014. Patients with the final diagnosis of MTLA were evaluated. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of EBUS-TBNA were calculated.Results: The prevalence of MTLA in all patients who had undergone EBUS-TBNA for mediastinal lymphadenopathy of unknown etiology was 5.2% (28/527). EBUS-TBNA was diagnostic in 21/28 (75%) patients, and the remaining 7 patients required additional procedures for confirmation of diagnosis. Sensitivity, specificity, PPV, NPV, and accuracy of combined cytopathological and microbiological examinations of EBUS-TBNA in the diagnosis of MTLA were 87.5%, 98.5%, 91.4%, 98%, and 94.4%, respectively. There were no major complications.Conclusion: EBUS-TBNA is a safe and effective procedure for the diagnosis of MTLA. When microbiological and cytopathological examinations of samples are combined, EBUS-TBNA demonstrates good diagnostic accuracy and NPV for the diagnosis of MTLA.
MeSH term(s)	Adult ; Aged ; Endoscopic Ultrasound-Guided Fine Needle Aspiration/methods ; Endoscopic Ultrasound-Guided Fine Needle Aspiration/statistics & numerical data ; Female ; Humans ; Lymph Nodes/diagnostic imaging ; Lymph Nodes/microbiology ; Lymph Nodes/pathology ; Male ; Mediastinal Diseases/diagnosis ; Mediastinal Diseases/microbiology ; Mediastinal Diseases/pathology ; Mediastinum/diagnostic imaging ; Mediastinum/microbiology ; Mediastinum/pathology ; Middle Aged ; Predictive Value of Tests ; Retrospective Studies ; Tuberculosis, Lymph Node/diagnosis ; Tuberculosis, Lymph Node/microbiology ; Tuberculosis, Lymph Node/pathology
Language	English
Publishing date	2017-12-19
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	1183461-4
ISSN	1303-6165 ; 1300-0144
ISSN (online)	1303-6165
ISSN	1300-0144
DOI	10.3906/sag-1606-110
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Zs.A 3242: Show issues

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Article: Clinical characteristics of nontuberculosis mycobacterial pulmonary infection in immunocompetent adult patients: 6 cases.

Çetinkaya, Pelin Duru / Anar, Ceyda / Özkan Aktoğu, Serir / Erer, Onur Fevzi / Şenol, Güneş

Tuberkuloz ve toraks

2017 Volume 65, Issue 4, Page(s) 344–348

Title translation	Bağışıklığı baskılanmamış erişkin hastalarda nontüberküloz mikobakteri infeksiyonu: 6 olgu nedeniyle.
Language	English
Publishing date	2017
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	2468802-2
ISSN	0494-1373
ISSN	0494-1373
DOI	10.5578/tt.48563
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Zs.A 6702: Show issues

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Article: In vitro effects of ciprofloxacin, levofloxacin and moxifloxacin on Mycobacterium tuberculosis isolates.

Yılmaz, Fethiye Ferda / Eraç, Bayrı / Ermertcan, Şafak / Çavuşoğlu, Cengiz / Biçmen, Can / Aktoğu Özkan, Serir / Hoşgör Limoncu, Mine

Tuberkuloz ve toraks

2018 Volume 66, Issue 1, Page(s) 32–36

Abstract: Introduction: Increased tuberculosis prevalence, and isolation of multidrug resistant (MDR) Mycobacterium tuberculosis strains frequently as causative organisms from tuberculosis infections are resulted in increasing need of new anti-tuberculosis drugs. ...

Title translation	Mycobacterium tuberculosis kökenleri üzerine siprofloksasin, levofloksasin ve moksifloksasinin in vitro etkinliği.
Abstract	Introduction: Increased tuberculosis prevalence, and isolation of multidrug resistant (MDR) Mycobacterium tuberculosis strains frequently as causative organisms from tuberculosis infections are resulted in increasing need of new anti-tuberculosis drugs. Nowadays, fluoroquinolones known to have fewer side effects than the other drugs used in treatment of tuberculosis are sometimes assessed even as first-line anti-tuberculosis drugs due to their in vitro and in vivo strong activity. It was aimed in this study to investigate phenotypically the fluoroquinolone susceptibility in MDR and non-MDR M. tuberculosis isolates. Materials and methods: A total of 126 MDR and non-MDR M. tuberculosis isolates from mycobacteriology laboratory of two hospitals in the Aegean Region of Turkey were included in the study. Ciprofloxacin (CIP), levofloxacin (LEV) and moxifloxacin (MXF) susceptibilities were assessed by agar proportion method according to the Clinical and Laboratory Standards Institute (CLSI) recommendations. Result: Twelve (15.2%), 5 (6.3%) and 4 (5.1%) of the MDR M. tuberculosis strains were resistant to CIP, LEV, MXF, respectively [resistance breakpoints (µg/mL); CIP (> 2), LEV (> 1), MXF (> 0.5)] while non-MDR strains were susceptible to CIP, LEV, MXF. Conclusions: Consequently, although high fluoroquinolone susceptibilities were evaluated as a pleasing data in this study, to preserve their efficiency for many years steadily, quinolone usage and resistance increment in MDR M. tuberculosis isolates should be monitored elaborately.
MeSH term(s)	Antitubercular Agents/pharmacology ; Antitubercular Agents/therapeutic use ; Ciprofloxacin/pharmacology ; Fluoroquinolones/pharmacology ; Humans ; Levofloxacin/pharmacology ; Microbial Sensitivity Tests ; Moxifloxacin ; Mycobacterium tuberculosis/drug effects ; Mycobacterium tuberculosis/isolation & purification ; Tuberculosis/drug therapy ; Tuberculosis, Multidrug-Resistant/drug therapy ; Turkey
Chemical Substances	Antitubercular Agents ; Fluoroquinolones ; Ciprofloxacin (5E8K9I0O4U) ; Levofloxacin (6GNT3Y5LMF) ; Moxifloxacin (U188XYD42P)
Language	English
Publishing date	2018-08-24
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	2468802-2
ISSN	0494-1373
ISSN	0494-1373
DOI	10.5578/tt.58677
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Zs.A 6702: Show issues

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Article: Multiple Pulmonary Arterial Aneurysms in Behçet’s Disease: Clinical and Radiologic Remission after Cyclophosphamide and Corticosteroid Therapy

Aktogu, Serir / Erer, Onur Fevzi / Ürpek, Gülcan / Soy, Ömer / Tibet, Gültekin

Respiration

2002 Volume 69, Issue 2, Page(s) 178–181

Abstract: Behçet’s disease (BD) with pulmonary arterial aneurysm is rare and often associated with a poor ...

Institution	Departments of Respiratory Medicine and Radiology, İzmir Training Hospital for Thoracic Medicine and Surgery, Yenişehir, Izmir, Turkey
Abstract	Behçet’s disease (BD) with pulmonary arterial aneurysm is rare and often associated with a poor prognosis. But there is also a chance that the aneurysm may completely resolve with medical therapy. A 39-year-old man presented with fever, malaise, bilateral chest pain, recurrent oral ulcers, and hemoptysis. The chest radiograph showed a round opacity in the right hilum. Computed tomography and magnetic resonance angiography (MRA) further revealed multiple, bilateral pulmonary arterial aneurysms consistent with the diagnosis of BD. The patient was started on a course of cyclophosphamide and corticosteroid therapy that resulted in cessation of his symptoms and complete resolution of radiologic findings. The chest radiograph and MRA reverted to normal on long-term follow-up. He is still alive and symptom-free 20 months after diagnosis.
Keywords	Behçet’s disease ; Pulmonary arteries ; Aneurysm ; Vasculitis
Language	English
Publishing date	2002-04-08
Publisher	S. Karger AG
Publishing place	Basel, Switzerland
Document type	Article
Note	Case Report
ZDB-ID	206674-9
ISSN	1423-0356 ; 0025-7931
ISSN (online)	1423-0356
ISSN	0025-7931
DOI	10.1159/000056324
Database	Karger publisher's database

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Article ; Online: Predictive value of platelet-to-lymphocyte ratio in exacerbation of chronic obstructive pulmonary disease.

Karadeniz, Gülistan / Aktoğu, Serir / Erer, Onur Fevzi / Kır, Serpil Bulaç / Doruk, Sibel / Demir, Melike / Sonat, Kübra

Biomarkers in medicine

2016 Volume 10, Issue 7, Page(s) 701–710

Abstract: ... with the forced expiratory volume in 1 s.: Conclusion: The PLR may be used as a useful and easily accessible tool for evaluating ...

Abstract	Aim: We aimed to assess the platelet-to-lymphocyte ratio (PLR) and platelet parameters in patients with chronic obstructive pulmonary disease (COPD). Methods: A total of 60 stable COPD patients, 50 acute exacerbation COPD patients and 50 healthy controls were enrolled in this study. Results: The platelet distribution width and PLR were higher and the mean platelet volume was lower in the COPD patients during acute exacerbation compared with the stable patients and controls. The PLR was negatively correlated with the forced expiratory volume in 1 s. Conclusion: The PLR may be used as a useful and easily accessible tool for evaluating the ongoing inflammation during stable period and the disease severity during acute exacerbations in COPD patients.
MeSH term(s)	Aged ; Area Under Curve ; Blood Platelets/cytology ; Blood Platelets/physiology ; C-Reactive Protein/analysis ; Case-Control Studies ; Disease Progression ; Female ; Forced Expiratory Volume ; Humans ; Lymphocytes/cytology ; Male ; Mean Platelet Volume ; Middle Aged ; Predictive Value of Tests ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/pathology ; ROC Curve ; Smoking
Chemical Substances	C-Reactive Protein (9007-41-4)
Language	English
Publishing date	2016-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2481014-9
ISSN	1752-0371 ; 1752-0363
ISSN (online)	1752-0371
ISSN	1752-0363
DOI	10.2217/bmm-2016-0046
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Zs.A 6985: Show issues

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Article: Contribution of cell block obtained by endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of malignant diseases and sarcoidosis.

Erer, Onur Fevzi / Erol, Serhat / Anar, Ceyda / Aydoğdu, Zekiye / Özkan, Serir Aktoğu

Endoscopic ultrasound

2016 Volume 6, Issue 4, Page(s) 265–268

Abstract: Aim: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a safe and minimally invasive procedure that can be performed in outpatient settings. Several studies have demonstrated the usefulness of EBUS-TBNA in the diagnosis of ... ...

Abstract	Aim: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a safe and minimally invasive procedure that can be performed in outpatient settings. Several studies have demonstrated the usefulness of EBUS-TBNA in the diagnosis of sarcoidosis and malignant diseases. This study focused on the role of cell block (CB) analysis in determining the diagnostic yield of EBUS-TBNA in malignant diseases and sarcoidosis. Materials and methods: The study was conducted at a training and research hospital. Records of patients who underwent EBUS-TBNA between March 2011 and December 2014 for diagnosed sarcoidosis or malignancy were retrospectively analyzed. Results of all EBUS-TBNA smears and CB were separately evaluated to determine the diagnostic value of each. Results: There were 84 sarcoidosis and 179 malignancy patients. In the malignancy group, CB contributed to cancer diagnosis in 15 (8.3%) patients and subclassification in 19 (10.6%) patients. In the sarcoidosis group, for 45.2% of patients (38/84), smears were not diagnostic but CB showed granulomatous inflammation. Conclusion: CB significantly increases the diagnostic yield of EBUS-TBNA for sarcoidosis. In our study, in the malignancy group the diagnostic yield was low but it was helpful for subclassification, especially for adenocarcinoma.
Language	English
Publishing date	2016-04-28
Publishing country	China
Document type	Journal Article
ZDB-ID	2998317-4
ISSN	2226-7190 ; 2303-9027
ISSN (online)	2226-7190
ISSN	2303-9027
DOI	10.4103/2303-9027.180763
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Article: Diagnostic yield of EBUS-TBNA for lymphoma and review of the literature.

Erer, Onur Fevzi / Erol, Serhat / Anar, Ceyda / Aydoğdu, Zekiye / Özkan, Serir Aktoğu

Endoscopic ultrasound

2016 Volume 6, Issue 5, Page(s) 317–322

Abstract: Aim: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), which enables cytological examination of mediastinal lymph node (LN) aspiration samples, is a safe and minimally invasive method for diagnosis and staging of lung cancer ... ...

Abstract	Aim: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), which enables cytological examination of mediastinal lymph node (LN) aspiration samples, is a safe and minimally invasive method for diagnosis and staging of lung cancer and diagnosis of diseases affecting mediastinal LNs. In this study, we investigated the yield of EBUS-TBNA for diagnosis of lymphoma and reviewed the literature since the British Thoracic Society (BTS) guidelines were published. Materials and methods: We retrospectively evaluated our database for patients who underwent EBUS between March 2011 and December 2014. One hundred eighty-nine patients with isolated mediastinal lymphadenopathy were included in the study. Patients with other causes of lymphadenopathy, such as lung cancer or extrathoracic malignancy, and those with pulmonary lesions accompanying mediastinal lymphadenopathy were excluded from the study. Patients with final diagnosed lymphoma were included in the study on the basis of a history of lymphoma or newly evaluated mediastinal lymphadenopathy. The sensitivity and negative predictive value (NPV) of EBUS-TBNA were calculated. Results: There were 13 patients with the final diagnosis of lymphoma. Eleven of them were new diagnoses and 2 patients were known chronic lymphocytic leukemia (CLL), and underwent EBUS-TBNA for determination of recurrence. Twelve EBUS-TBNA procedures were performed for suspected new cases. Three (25%) were diagnostic, 2 (16.7%) were suspicious for lymphoma and underwent further interventions for definite diagnosis, and 7 (58.3%) were false negative. All 3 patients diagnosed with EBUS-TBNA were non-Hodgkin lymphoma (NHL). None of the Hodgkin lymphoma (HL) cases could be diagnosed with EBUS-TBNA. The overall diagnostic sensitivity and NPV of EBUS-TBNA in detecting lymphoma was 65% and 96.1%, respectively. For the newly diagnosed lymphoma cases, EBUS-TBNA had a sensitivity of 61.1%. Conclusion: In conclusion, we believe that since the publication of the BTS guidelines, the value of EBUS-TBNA in the diagnosis of lymphoma still remains controversial. EBUS-TBNA can be the first diagnostic modality in diagnosis of recurrent lymphomas. However, for suspected new cases, especially for HL, the diagnostic yield of EBUS-TBNA is low and negative results do not exclude lymphoma. Further interventions such as mediastinoscopy should be performed for high-suspicion patients.
Language	English
Publishing date	2016-04-28
Publishing country	China
Document type	Journal Article
ZDB-ID	2998317-4
ISSN	2226-7190 ; 2303-9027
ISSN (online)	2226-7190
ISSN	2303-9027
DOI	10.4103/2303-9027.180762
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Article: Toplum Kökenli Pnömonisi Olan Erişkin Hastalarda Konvansiyonel ve Multipleks PCR Yöntemleriyle Bakteriyel Etiyolojinin Araştırılması

Kurutepe, Semra / Ecemiş, Talat / Ozgen, Aylin / Biçmen, Can / Celik, Pınar / Aktoğu Özkan, Serir / Sürücüoğlu, Süheyla

Mikrobiyoloji bulteni

2012 Volume 46, Issue 4, Page(s) 523–531

Abstract: ... The leading organism was S.pneumoniae (n= 32, 25%), followed by H.influenzae and M.pneumoniae (n= 9, 7%), gram ... 11.7%), and mixed infections in 14 (10.9%) patients. The detection rate of microorganisms (S ... against S.pneumoniae, M.pneumoniae and H.influenzae in our region. ...

Title translation	Investigation of bacterial etiology with conventional and multiplex PCR methods in adult patients with community-acquired pneumonia.
Abstract	Community-acquired pneumonia (CAP) is still a serious life-threatening disease, in which the etiologic agent cannot be identified in more than 50% of patients despite advanced diagnostic methods. The most commonly used methods in the determination of CAP etiology are culture and serological tests. Since early and accurate therapy reduces the mortality in CAP cases, rapid and reliable diagnostic methods are needed. The aim of this study was to determine the bacterial etiology in adult patients with CAP by implementing multiplex polymerase chain reaction/reverse line blot hybridization (M-PCR/RLBH) assay combined with conventional methods. A total of 128 cases (94 were male; age range: 19-81 years, mean age: 58) who were admitted to our hospital and clinically diagnosed as CAP between November 2008 - November 2010, were included in the study. Respiratory samples (sputum and/or bronchoalveolar lavage) obtained from patients were searched by M-PCR/RLBH method (Gen ID®, Autoimmun Diagnostika GmbH, Germany) in terms of the presence of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, Chlamydia pneumoniae and Legionella pneumophila nucleic acids. The samples were simultaneously inoculated onto 5% sheep blood agar, chocolate agar, haemophilus isolation agar, buffered charcoal yeast extract-selective agar and EMB agar media for cultivation. Serum samples obtained from the cases were tested for IgM and IgG antibodies against C.pneumoniae by microimmunofluorescence (Focus Diagnostic, USA) and against L.pneumophila and M.pneumoniae by indirect immunofluorescence (Euroimmun, Germany) methods. The bacterial etiology was identified in 59 (46.1%) of 128 patients with CAP and a total of 73 pathogens were detected. The leading organism was S.pneumoniae (n= 32, 25%), followed by H.influenzae and M.pneumoniae (n= 9, 7%), gram-negative bacilli (n= 10, 7.8%), M.catarrhalis (n= 6, 4.7%), C.pneumoniae (n= 4, 3.2%), L.pneumophila (n= 2, 1.6%) and Staphylococcus aureus (n= 1, 1.4%). Infection with atypical pathogens were detected in 15 (11.7%), and mixed infections in 14 (10.9%) patients. The detection rate of microorganisms (S.pneumoniae, H.influenzae, M.catarrhalis, C.pneumoniae, L.pneumophilia, M.pneumoniae) searched by M-PCR/RLBH method was 41.4% (53/128), while those microorganisms were detected in 23.4% (30/128) of the patients by conventional methods, representing a significant difference (p< 0.05). It was concluded that M-PCR/RLBH method supplemented the determination of bacterial etiology in CAP cases by increasing the rate of detection from 23.4% to 41.4%. The results indicated that empirical treatment of CAP should primarily include antibiotics against S.pneumoniae, M.pneumoniae and H.influenzae in our region.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Bacteria/classification ; Bacteria/isolation & purification ; Bronchoalveolar Lavage Fluid/microbiology ; Community-Acquired Infections/microbiology ; Female ; Fluorescent Antibody Technique/methods ; Humans ; Male ; Middle Aged ; Multiplex Polymerase Chain Reaction ; Nucleic Acid Hybridization ; Pneumonia, Bacterial/microbiology ; Sputum/microbiology ; Young Adult
Language	Turkish
Publishing date	2012-10
Publishing country	Turkey
Document type	English Abstract ; Journal Article
ZDB-ID	985146-x
ISSN	0374-9096
ISSN	0374-9096
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Zs.A 3943: Show issues

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Article: Hydatid cyst presenting as an eosinophilic pleural effusion.

Aktoğu Ozkan, Serir / Erer, Onur F / A Yalçin, Yavuz / Yuncu, Gökhan / Aydoğdu, Zekiye

Respirology (Carlton, Vic.)

2007 Volume 12, Issue 3, Page(s) 462–464

Abstract: A 61-year-old woman presented with an eosinophilic pleural effusion, secondary to transdiaphragmatic intrapleural spread of an hepatic hydatid cyst. Right posterolateral thoracotomy and frenotomy revealed a loculated pleural effusion associated with a 10 ...

Abstract	A 61-year-old woman presented with an eosinophilic pleural effusion, secondary to transdiaphragmatic intrapleural spread of an hepatic hydatid cyst. Right posterolateral thoracotomy and frenotomy revealed a loculated pleural effusion associated with a 10 x 8 cm hydatid cyst in the posterior segment of the liver. Hydatid disease should be included in the differential diagnosis of eosinophilic pleural effusions in endemic regions.
MeSH term(s)	Animals ; Diagnosis, Differential ; Echinococcosis, Hepatic/complications ; Echinococcosis, Pulmonary/complications ; Echinococcosis, Pulmonary/diagnosis ; Echinococcosis, Pulmonary/pathology ; Echinococcus granulosus/pathogenicity ; Eosinophils/pathology ; Female ; Humans ; Lung/diagnostic imaging ; Lung/parasitology ; Middle Aged ; Pleural Effusion/diagnosis ; Pleural Effusion/etiology ; Pleural Effusion/pathology ; Tomography, X-Ray Computed
Language	English
Publishing date	2007-05
Publishing country	Australia
Document type	Case Reports ; Journal Article
ZDB-ID	1435849-9
ISSN	1440-1843 ; 1323-7799
ISSN (online)	1440-1843
ISSN	1323-7799
DOI	10.1111/j.1440-1843.2007.01054.x
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