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  1. Book: Fetal and neonatal physiology / 2 / Richard A. Polin ; William W. Fox ; Steven H. Abman

    Polin, Richard A. / Fox, William W. / Abman, Steven H.

    2004  

    Author's details Richard A. Polin ; William W. Fox ; Steven H. Abman
    Collection Fetal and neonatal physiology
    Language English
    Size XXXII S., S. 1004 - 1960, XLVIII S. : Ill., graph. Darst.
    Edition 3. ed.
    Publisher Saunders u.a.
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT013828822
    ISBN 9-997-62831-4 ; 978-9-997-62831-2
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Fetal and neonatal physiology / 1 / Richard A. Polin ; William W. Fox ; Steven H. Abman

    Polin, Richard A. / Fox, William W. / Abman, Steven H.

    2004  

    Author's details Richard A. Polin ; William W. Fox ; Steven H. Abman
    Collection Fetal and neonatal physiology
    Language English
    Size XXXII, 1001, LVIII S. : Ill., graph. Darst.
    Edition 3. ed.
    Publisher Saunders u.a.
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT013828805
    ISBN 9-997-62826-8 ; 978-9-997-62826-8
    Database Catalogue ZB MED Medicine, Health

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  3. Book: Fetal and neonatal physiology / Volume 1

    Polin, Richard A. / Fox, William W. / Abman, Steven H.

    2022  

    Author's details Richard A. Polin ; William W. Fox ; Steven H. Abman
    Collection Fetal and neonatal physiology
    Language English
    Size xxxviii, 940, i51 Seiten, Illustrationen, Diagramme
    Edition Sixth edition
    Publisher Saunders u.a.
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    Accompanying material Zugang zu Online-Ausgabe über Code
    HBZ-ID HT021017683
    ISBN 978-0-323-82555-9 ; 0-323-82555-9
    Database Catalogue ZB MED Medicine, Health

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  4. Book: Fetal and neonatal physiology / Volume 2

    Polin, Richard A. / Fox, William W. / Abman, Steven H.

    2022  

    Author's details Richard A. Polin ; William W. Fox ; Steven H. Abman
    Collection Fetal and neonatal physiology
    Language English
    Size xxxviii, i51 Seiten, Seiten 941 - 1854, Illustrationen, Diagramme
    Edition Sixth edition
    Publisher Saunders u.a.
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT021017687
    ISBN 978-0-323-82556-6 ; 0-323-82556-7
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: The new APS: lingering lessons.

    Abman, Steven H

    Pediatric research

    2022  Volume 92, Issue 5, Page(s) 1217–1222

    Language English
    Publishing date 2022-03-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 4411-8
    ISSN 1530-0447 ; 0031-3998
    ISSN (online) 1530-0447
    ISSN 0031-3998
    DOI 10.1038/s41390-022-02006-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Characterization of Early Pulmonary Hypertension in Infants Born Preterm: A Key Step Toward Improving Outcomes.

    Abman, Steven H

    The Journal of pediatrics

    2022  Volume 251, Page(s) 44–46

    MeSH term(s) Infant, Newborn ; Infant ; Humans ; Hypertension, Pulmonary/diagnosis ; Infant, Premature ; Bronchopulmonary Dysplasia
    Language English
    Publishing date 2022-09-10
    Publishing country United States
    Document type Editorial
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2022.09.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Pulmonary Hypertension in Established Bronchopulmonary Dysplasia: Physiologic Approaches to Clinical Care.

    Abman, Steven H / Lakshminrusimha, Satyan

    Clinics in perinatology

    2024  Volume 51, Issue 1, Page(s) 195–216

    Abstract: Preterm infants with bronchopulmonary dysplasia (BPD) are prone to develop pulmonary hypertension (PH). Strong laboratory and clinical data suggest that antenatal factors, such as preeclampsia, chorioamnionitis, oligohydramnios, and placental dysfunction ...

    Abstract Preterm infants with bronchopulmonary dysplasia (BPD) are prone to develop pulmonary hypertension (PH). Strong laboratory and clinical data suggest that antenatal factors, such as preeclampsia, chorioamnionitis, oligohydramnios, and placental dysfunction leading to fetal growth restriction, increase susceptibility for BPD-PH after premature birth. Echocardiogram metrics and serial assessments of NT-proBNP provide useful tools to diagnose and monitor clinical course during the management of BPD-PH, as well as monitoring for such complicating conditions as left ventricular diastolic dysfunction, shunt lesions, and pulmonary vein stenosis. Therapeutic strategies should include careful assessment and management of underlying airways and lung disease, cardiac performance, and systemic hemodynamics, prior to initiation of PH-targeted drug therapies.
    MeSH term(s) Infant ; Infant, Newborn ; Female ; Humans ; Pregnancy ; Bronchopulmonary Dysplasia/complications ; Bronchopulmonary Dysplasia/therapy ; Hypertension, Pulmonary/therapy ; Hypertension, Pulmonary/diagnosis ; Infant, Premature ; Placenta ; Premature Birth
    Language English
    Publishing date 2024-01-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 193116-7
    ISSN 1557-9840 ; 0095-5108
    ISSN (online) 1557-9840
    ISSN 0095-5108
    DOI 10.1016/j.clp.2023.12.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Neonatal Pulmonary Hypertension: Phenotypes, Physiology, and Management.

    Lakshminrusimha, Satyan / Abman, Steven H

    Clinics in perinatology

    2023  Volume 51, Issue 1, Page(s) xix–xxii

    MeSH term(s) Infant, Newborn ; Humans ; Hypertension, Pulmonary/therapy ; Hypertension ; Phenotype
    Language English
    Publishing date 2023-12-13
    Publishing country United States
    Document type Editorial
    ZDB-ID 193116-7
    ISSN 1557-9840 ; 0095-5108
    ISSN (online) 1557-9840
    ISSN 0095-5108
    DOI 10.1016/j.clp.2023.11.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Pulmonary Hypertension: The Hidden Danger for Newborns.

    Abman, Steven H

    Neonatology

    2021  Volume 118, Issue 2, Page(s) 211–217

    Abstract: Despite growing awareness of the clinical importance of pulmonary hypertension (PH) in preterm infants, uncertainty persists regarding the different clinical settings in which abnormalities of pulmonary vascular growth, function, and structure contribute ...

    Abstract Despite growing awareness of the clinical importance of pulmonary hypertension (PH) in preterm infants, uncertainty persists regarding the different clinical settings in which abnormalities of pulmonary vascular growth, function, and structure contribute to high morbidity and mortality, and potential interventions to improve outcomes are uncertain. A major gap for improving outcomes of preterm infants with PH has been the limited characterization of the distinct settings of PH and related disease-specific mechanisms in preterm infants that represent diverse pulmonary vascular phenotypes of prematurity. In comparison with term newborns, preterm infants have a higher risk for developing hypoxemia due to suprasystemic levels of PH in preterm infants shortly after birth or persistent pulmonary hypertension of the newborn (PPHN). Variable and milder levels of PH have also been demonstrated in preterm infants without evidence of severe hypoxemic respiratory failure, suggesting delayed vascular transition of the lung which is associated with higher risks of mortality and developing bronchopulmonary dysplasia (BPD). In addition, early echocardiographic signs of PH at day 7 are strongly associated with the subsequent diagnosis of BPD, late PH, and respiratory disease throughout early childhood. In infants with evolving or established BPD, PH that persists beyond the first few months of life in preterm infants is associated with high mortality. Recent data further show that PVD can persist and cause PH in prematurely born adults. Overall, more precise characterization and studies of diverse pulmonary vascular phenotypes in preterm infants will be likely to improve the development of therapeutic strategies to optimize care of preterm infants with PH.
    MeSH term(s) Bronchopulmonary Dysplasia/diagnosis ; Child, Preschool ; Humans ; Hypertension, Pulmonary/diagnosis ; Infant, Newborn ; Infant, Premature ; Lung ; Persistent Fetal Circulation Syndrome
    Language English
    Publishing date 2021-05-05
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 2266911-5
    ISSN 1661-7819 ; 1661-7800
    ISSN (online) 1661-7819
    ISSN 1661-7800
    DOI 10.1159/000516107
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Oxygen Targets in Neonatal Pulmonary Hypertension: Individualized, "Precision-Medicine" Approach.

    Lakshminrusimha, Satyan / Abman, Steven H

    Clinics in perinatology

    2023  Volume 51, Issue 1, Page(s) 77–94

    Abstract: Oxygen is a specific pulmonary vasodilator. Hypoxemia causes pulmonary vasoconstriction, and normoxia leads to pulmonary vasodilation. However, hyperoxia does not enhance pulmonary vasodilation but causes oxidative stress. There are no clinical trials ... ...

    Abstract Oxygen is a specific pulmonary vasodilator. Hypoxemia causes pulmonary vasoconstriction, and normoxia leads to pulmonary vasodilation. However, hyperoxia does not enhance pulmonary vasodilation but causes oxidative stress. There are no clinical trials evaluating optimal oxygen saturation or Pao
    MeSH term(s) Infant, Newborn ; Humans ; Oxygen ; Hypertension, Pulmonary/therapy ; Lung ; Vasodilator Agents ; Hypoxia
    Chemical Substances Oxygen (S88TT14065) ; Vasodilator Agents
    Language English
    Publishing date 2023-12-28
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 193116-7
    ISSN 1557-9840 ; 0095-5108
    ISSN (online) 1557-9840
    ISSN 0095-5108
    DOI 10.1016/j.clp.2023.12.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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