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  1. Book: Sleep Medicine

    Gozal, David / Sharafkhaneh, Amir

    A Comprehensive Guide for Transitioning Pediatric to Adult Care

    2023  

    Author's details Amir Sharafkhaneh, MD, PhD, Professor of Medicine, Section of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, Staff Physician, Sleep Disorders & Research Center, Medical Care Line, Michael E. DeBakey VA Medical Center 2002 Holcombe Blvd., Houston, Texas, 77030 Office: 713-794-7318Fax: 713-794-7558 Email: amirs@bcm.edu § David Gozal, MD, MBA, PhD (Hon), Marie M. and Harry L. Smith Endowed Chair, Chairperson, Department of Child Health, Pediatrician-in-Chief, MU Women's and Children's Hospital, University of Missouri School of Medicine 400 N Keene St, Suite 010, Columbia, MO 65201, USA Office: 573-882-6882Fax: 573-884-5179 Email: gozald@health.missouri.edu §
    Keywords Pediatrics ; Transition ; sleep disorders ; physiology ; psychology ; sleep ; pediatrics ; adult ; transition
    Language English
    Size 300 p.
    Edition 1
    Publisher Springer International Publishing
    Document type Book
    Note PDA Manuell_21
    Format 160 x 241 x 21
    ISBN 9783031300097 ; 3031300092
    Database PDA

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  2. Book ; Online ; E-Book: Fatigue management

    Sharafkhaneh, Amir / Hirshkowitz, Max

    principles and practices for improving workplace safety

    2018  

    Author's details Amir Sharafkhaneh, Max Hirshkowitz editors
    Keywords Psychiatry ; Neurology ; Pneumology
    Subject code 616.89
    Language English
    Size 1 Online-Ressource (X, 226 Seiten), Illustrationen
    Publisher Springer
    Publishing place New York, NY
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019821654
    ISBN 978-1-4939-8607-1 ; 9781493986057 ; 1-4939-8607-4 ; 1493986058
    DOI 10.1007/978-1-4939-8607-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  3. Book ; Online ; E-Book: Depression and anxiety in patients with chronic respiratory diseases

    Yohannes, Abebaw Mengistu / Hanania, Nicola / Kunik, Mark Edwin / Sharafkhaneh, Amir

    2017  

    Author's details Amir Sharafkhaneh, Abebaw Mengistu Yohannes, Nicola Alexander Hanania, Mark E. Kunik, editors
    Keywords anxiety ; asthma ; cystic fibrosis ; depression ; lung disease ; respiratory
    Subject code 610
    Language English
    Size 1 Online-Ressource (x, 200 Seiten)
    Publisher Springer New York
    Publishing place New York, NY
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019366465
    ISBN 978-1-493-97009-4 ; 9781493970070 ; 1-493-97009-7 ; 1493970070
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Validation of electronic diagnostic codes for rapid eye movement sleep behavior disorder.

    Jones, Melissa B / Schenck, Carlos H / Azarian, Mehrnaz / Jorge, Ricardo E / Sharafkhaneh, Amir / Razjouyan, Javad

    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

    2024  

    Abstract: We investigated the accuracy ... ...

    Abstract We investigated the accuracy of
    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2397213-0
    ISSN 1550-9397 ; 1550-9389
    ISSN (online) 1550-9397
    ISSN 1550-9389
    DOI 10.5664/jcsm.11190
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  5. Book: COPD

    Hanania, Nicola / Sharafkhaneh, Amir

    a guide to diagnosis and clinical management

    (Respiratory medicine)

    2011  

    Author's details Nicola Hanania ; Amir Sharafkhaneh, ed
    Series title Respiratory medicine
    Language English
    Size XIV, 319 S. : Ill., graph. Darst.
    Publisher Humana Press
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT016677435
    ISBN 978-1-58829-949-9 ; 1-58829-949-X ; 9781597453578 ; 1597453579
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2011 A 745 order for loan Magazin

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  6. Article: Impact of Obstructive Sleep Apnea Diagnosed Using the STOP-Bang Questionnaire Scale on Postoperative Complications Following Major Cardiac Surgery: A Prospective Observational Cohort Study.

    Javaherforooshzadeh, Fatemeh / Amjadzadeh, Mohammadreza / Haybar, Habib / Sharafkhaneh, Amir

    Cureus

    2022  Volume 14, Issue 6, Page(s) e26102

    Abstract: Purpose Obstructive sleep apnea (OSA) is a common and often undiagnosed condition in patients undergoing major surgeries, including cardiac surgery. This disorder is associated with peri- and postoperative problems. This study measured the association ... ...

    Abstract Purpose Obstructive sleep apnea (OSA) is a common and often undiagnosed condition in patients undergoing major surgeries, including cardiac surgery. This disorder is associated with peri- and postoperative problems. This study measured the association between OSA and peri- and postoperative complications in patients undergoing elective cardiac surgery. Methods Candidates for elective cardiac surgery were evaluated for OSA by the STOP-Bang questionnaire before the surgery. We evaluated patients before and after the operation regarding the cardiac, respiratory, and neurologic complications. We divided the participants into high-risk (score of 5-8), intermediate-risk (score of 3-4), and low-risk groups (score of 0-2) based on the STOP-Bang questionnaire. Results Of the 306 patients who underwent cardiac surgery, 173 (56.5%) were in the high-risk group, 100 (32.7%) were in the intermediate-risk group, and 33 (10.8%) were in the low-risk group for OSA. Patients in the high-risk group were significantly older than the other two groups (p value=0.013), had higher BMI (p<0.001), and suffered more from relevant comorbid conditions, including diabetes mellitus, hypertension, and hyperlipidemia (all p-values significant at < 0.05). However, not significant, patients in the high-risk group suffered more from postoperative complications including cardiac, respiratory, and neurological complications. Conclusion OSA is common in patients undergoing cardiac surgery. Our findings indicate that these patients manifest a higher incidence of postoperative complications compared to those with a lower risk of OSA. Because of the limited use of polysomnography, a simple STOP-Bang questionnaire is beneficial to screen patients for the risk of OSA peri-operatively, and patients diagnosed with OSA can get extra care during and after the surgery.
    Language English
    Publishing date 2022-06-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.26102
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  7. Article ; Online: The role of lncRNAs in intermittent hypoxia and sleep Apnea: A review of experimental and clinical evidence.

    Moradi, Mohammad-Taher / Fadaei, Reza / Sharafkhaneh, Amir / Khazaie, Habibolah / Gozal, David

    Sleep medicine

    2023  Volume 113, Page(s) 188–197

    Abstract: In this narrative review, we present a comprehensive assessment on the putative roles of long non-coding RNAs (lncRNAs) in intermittent hypoxia (IH) and sleep apnea. Collectively, the evidence from cell culture, animal, and clinical research studies ... ...

    Abstract In this narrative review, we present a comprehensive assessment on the putative roles of long non-coding RNAs (lncRNAs) in intermittent hypoxia (IH) and sleep apnea. Collectively, the evidence from cell culture, animal, and clinical research studies points to the functional involvement of lncRNAs in the pathogenesis, diagnosis, and potential treatment strategies for this highly prevalent disorder. Further research is clearly warranted to uncover the mechanistic pathways and to exploit the therapeutic potential of lncRNAs, thereby improving the management and outcomes of patients suffering from sleep apnea.
    MeSH term(s) Animals ; Humans ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; Sleep Apnea Syndromes/genetics ; Sleep Apnea Syndromes/pathology ; Hypoxia/genetics
    Chemical Substances RNA, Long Noncoding
    Language English
    Publishing date 2023-11-14
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2012041-2
    ISSN 1878-5506 ; 1389-9457
    ISSN (online) 1878-5506
    ISSN 1389-9457
    DOI 10.1016/j.sleep.2023.11.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Obstructive sleep apnea modulates clinical outcomes post-acute myocardial infarction: A large longitudinal veterans' dataset report.

    Agrawal, Ritwick / Sharafkhaneh, Amir / Nambi, Vijay / BaHammam, Ahmed / Razjouyan, Javad

    Respiratory medicine

    2023  Volume 211, Page(s) 107214

    Abstract: ... advantages during and after acute myocardial infarction (AMI). We hypothesized in patients who were admitted ... was in-hospital mortality during AMI hospitalization. We analyzed the data using logistic regression ... veterans with any sleep diagnosis, 76,359 patients were hospitalized with a diagnosis of AMI. We observed ...

    Abstract Background: While the longer-term Obstructive Sleep apnea (OSA)-related intermittent hypoxia (IH) leads to various comorbidities, it has become increasingly evident that OSA confers protective advantages during and after acute myocardial infarction (AMI). We hypothesized in patients who were admitted with acute MI, the presence of OSA is associated with lower in-hospital mortality compared to those without a prior diagnosis of OSA.
    Methods: In this nationwide retrospective study utilizing Veterans Health Administration records, we included patients hospitalized for MI with a history of sleep disorders from 1999 to 2020. We divided patients into two cohorts: those with OSA and those without OSA. The primary outcome was in-hospital mortality during AMI hospitalization. We analyzed the data using logistic regression and calculated the odds ratio of in-hospital mortality.
    Results: Out of more than four million veterans with any sleep diagnosis, 76,359 patients were hospitalized with a diagnosis of AMI. We observed 30,116 with OSA (age, 64 ± 10 years; BMI, 33 ± 7 kg/m
    Conclusions: Presence of OSA is associated with lower in-hospital mortality among patients admitted for AMI, after adjusting for various demographic and co-morbidity factors. This study highlights the complex relationship between OSA and cardiovascular health and highlights the need for further research in this area.
    MeSH term(s) Humans ; Middle Aged ; Aged ; Aged, 80 and over ; Retrospective Studies ; Veterans ; Myocardial Infarction/complications ; Myocardial Infarction/epidemiology ; Sleep Apnea, Obstructive/complications ; Sleep Apnea, Obstructive/epidemiology ; Sleep Apnea, Obstructive/diagnosis ; Comorbidity ; Syndrome ; Risk Factors
    Language English
    Publishing date 2023-03-15
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1003348-8
    ISSN 1532-3064 ; 0954-6111
    ISSN (online) 1532-3064
    ISSN 0954-6111
    DOI 10.1016/j.rmed.2023.107214
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  9. Article ; Online: Pimavanserin 34 mg at Bedtime for the Treatment of Insomnia in 6 Veterans With Posttraumatic Stress Disorder.

    Jones, Melissa B / Agrawal, Ritwick / Sharafkhaneh, Amir / Bhatti, Gursimrat / Li, Ruosha / Marsh, Laura / Jorge, Ricardo E

    The Journal of clinical psychiatry

    2023  Volume 84, Issue 6

    Language English
    Publishing date 2023-11-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 716287-x
    ISSN 1555-2101 ; 0160-6689
    ISSN (online) 1555-2101
    ISSN 0160-6689
    DOI 10.4088/JCP.23br14992
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  10. Article ; Online: Obesity paradox or hypoxia preconditioning: How obstructive sleep apnea modifies the Obesity-MI relationship.

    Sharafkhaneh, Amir / Agrawal, Ritwick / Nambi, Vijay / BaHammam, Ahmed / Razjouyan, Javad

    Sleep medicine

    2023  Volume 110, Page(s) 132–136

    Abstract: Objectives: The objective of this study was to evaluate the interaction between obesity and obstructive sleep apnea on acute MI in hospital mortality.: Methods: This retrospective cohort study utilized Veterans Health Administration data from years ... ...

    Abstract Objectives: The objective of this study was to evaluate the interaction between obesity and obstructive sleep apnea on acute MI in hospital mortality.
    Methods: This retrospective cohort study utilized Veterans Health Administration data from years 1999-2020. Participants were categorized according to their body mass index (BMI) to non-obese (BMI <30) and obese (BMI ≥30) groups. Clinical obstructive sleep apnea (SA) diagnosis was confirmed using ICD9/10 codes and the study subgroups included non-obese with no obstructive sleep apnea (nOB-nSA), non-Obese with obstructive sleep apnea (nOB-SA), obese with no obstructive sleep apnea (OB-nSA), and obese with obstructive sleep apnea (OB-SA). The primary outcome was odds ratio of in-hospital mortality during the hospitalization with acute MI as the principal diagnosis adjusted for age, gender, race, ethnicity, and Charlson comorbidity index (CCI) with the nOB-nSA group as the comparison group.
    Results: Among 72,036 veterans with acute-MI hospitalization, individuals with obesity and obstructive sleep apnea (OB-SA) had the lowest in-hospital mortality rate (1.0%) compared to those without obesity and obstructive sleep apnea (nOB-nSA, 2.8%), with obesity but without obstructive sleep apnea (OB-nSA, 2.4%), and with obesity and obstructive sleep apnea (nOB-SA, 1.4%). The adjusted odds ratio for mortality, compared to nOB-nSA, was 9% higher but not significant in OB-nSA (aOR, 1.09, 95%CI: 0.95, 1.25), 46% lower in OB-nSA (aOR, 0.54, 95%CI: 0.45, 0.66), and 52% lower in OB-SA (aOR, 0.48: 95%CI: 0.41, 0.57).
    Conclusion: Our data suggest that the association between obesity and improved survival in acute MI is largely driven by the presence of sleep apnea.
    MeSH term(s) Humans ; Body Mass Index ; Hypoxia ; Myocardial Infarction ; Obesity/complications ; Obesity Paradox ; Retrospective Studies ; Sleep Apnea Syndromes ; Sleep Apnea, Obstructive
    Language English
    Publishing date 2023-08-02
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2012041-2
    ISSN 1878-5506 ; 1389-9457
    ISSN (online) 1878-5506
    ISSN 1389-9457
    DOI 10.1016/j.sleep.2023.07.035
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