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  1. Book: Microbial metabolic engineering

    Santos, Christine Nicole S. / Ajikumar, Parayil Kumaran

    methods and protocols

    (Methods in molecular biology ; 1927 ; Springer protocols)

    2019  

    Author's details edited by Christine Nicole S. Santos and Parayil Kumaran Ajikumar
    Series title Methods in molecular biology ; 1927
    Springer protocols
    Collection
    Language English
    Size x, 252 Seiten, Illustrationen
    Publisher Humana Press
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT019995897
    ISBN 978-1-4939-9141-9 ; 9781493991426 ; 1-4939-9141-8 ; 1493991426
    Database Catalogue ZB MED Medicine, Health

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  2. Article: Introducing nurse prescribing in Gibraltar: the impact on palliative care.

    Santos-Willshere, Jamesina / Pizarro, Nicole

    British journal of nursing (Mark Allen Publishing)

    2022  Volume 31, Issue 3, Page(s) 162–168

    Abstract: This article critically explores the impact of the introduction of nurse prescribing on palliative care in Gibraltar. A preliminary audit review of the prescriptions issued by the two palliative independent nurse prescribers over their first full ... ...

    Abstract This article critically explores the impact of the introduction of nurse prescribing on palliative care in Gibraltar. A preliminary audit review of the prescriptions issued by the two palliative independent nurse prescribers over their first full calendar year of prescribing (2020) revealed two primary areas of impact: facilitating end-of-life care at home and improving anticipatory prescribing for end-of-life symptom management. These initial findings will be discussed in the context of the challenges and facilitators encountered during the first year of prescribing practice. Challenges were primarily related to the introduction of an advanced nursing role into an existing medical paradigm. Identified facilitators included comprehensive record keeping, collaborative working and the development of local guidelines, as well as the support of management and peers. The article concludes with a recommendation for further audits of prescribing data as a way to measure the impact of the new role and to inform future palliative service development.
    Language English
    Publishing date 2022-02-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1119191-0
    ISSN 0966-0461
    ISSN 0966-0461
    DOI 10.12968/bjon.2022.31.3.162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Equine-Assisted Therapeutic Intervention in Institutionalized Children: Case Studies.

    Matias, Ana Rita / Santos, Graça Duarte / Almeida, Nicole

    International journal of environmental research and public health

    2023  Volume 20, Issue 4

    Abstract: A significant number of institutionalized children have behavior problems. Socio-emotional skills are fundamental for their adaptation and success throughout life and are usually weakened in this population. Equine-assisted services (EAS) are a form of ... ...

    Abstract A significant number of institutionalized children have behavior problems. Socio-emotional skills are fundamental for their adaptation and success throughout life and are usually weakened in this population. Equine-assisted services (EAS) are a form of therapeutic mediation that facilitates and requires the practitioner's participation, contributing to the promotion of various psychomotor and socio-emotional dimensions. This study was developed during 17 sessions of EAS with a psychomotor intervention, which took place individually and weekly and lasted approximately 45 min, with three institutionalized children. A quantitative and qualitative assessment was carried out before and after the intervention to study the effects of an EAS intervention on socio-emotional competencies in the three institutionalized children. There was an improvement in skills, with an impact on intrapersonal skills and marked improvement in self-regulation and self-control, in addition to an improvement in the intentionality of movement and adequacy of gesture to the context. This type of intervention underlies a renewed educational and therapeutic approach, contributing to mental health promotion in this population.
    MeSH term(s) Animals ; Horses ; Humans ; Child ; Child, Institutionalized ; Emotions ; Health Promotion
    Language English
    Publishing date 2023-02-06
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20042846
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Refusal to Bear Weight in a Previously Healthy 8-year-old Girl.

    Sherwood, Karla / Santos, Christine / Rao, Latha / Webb, Nicole

    Pediatrics in review

    2022  Volume 42, Issue 12, Page(s) 698–701

    MeSH term(s) Child ; Female ; Health Status ; Humans ; Weight-Bearing
    Language English
    Publishing date 2022-08-26
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 774515-1
    ISSN 1526-3347 ; 0191-9601
    ISSN (online) 1526-3347
    ISSN 0191-9601
    DOI 10.1542/pir.2020-0085
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Modified Vertical Parasagittal Sub-Insular Hemispherotomy-Case Series and Technical Note.

    Del Gaudio, Nicole / Ferrao Santos, Susana / Raftopoulos, Christian

    Brain sciences

    2023  Volume 13, Issue 10

    Abstract: 1) Background: Hemispherotomy is the generally accepted treatment for hemispheric drug-resistant epilepsy (DRE). Lateral or vertical approaches are performed according to the surgeon's preference. Multiple technical variations have been proposed since ... ...

    Abstract (1) Background: Hemispherotomy is the generally accepted treatment for hemispheric drug-resistant epilepsy (DRE). Lateral or vertical approaches are performed according to the surgeon's preference. Multiple technical variations have been proposed since Delalande first described his vertical technique. We propose a sub-insular variation of the vertical parasagittal hemispherotomy (VPH) and describe our case series of patients operated on using this procedure. (2) Methods: Data from a continuous series of patients with hemispheric DRE who were operated on by the senior author (CR) using the modified sub-insular VPH technique were analyzed retrospectively. Pre-operative demographic and epilepsy characteristics, functional outcome, and surgical complications were extracted from medical charts. (3) Results: Twenty-five patients were operated on between August 2008 and August 2023; 23 have at least 3 months of follow-up. Of this group, 20 (86.9%) patients are seizure-free. Only two patients developed postoperative hydrocephalus (8.7%). All patients who were able to walk autonomously preoperatively and 20 (86.9%) of those with follow-up were able to walk without assistance. A total of 17 (74%) patients were able to perform adapted social activities at the latest follow-up. (4) Conclusions: Modified sub-insular VPH is a successful surgical technique for hemispheric DRE with seizure freedom rates similar to the largest series reported in the literature. Compared to other series, patients who were operated on with our modified technique had a lower rate of postoperative hydrocephalus and excellent long-term motor and cognitive outcomes.
    Language English
    Publishing date 2023-09-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci13101395
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The use of rubber dam in the survival of RMGIC restorations in primary molars: a 30-month randomized controlled clinical trial.

    Brum, Vanessa Dos Santos / Borges, Maria Luiza Vieira / Santos, Nicole Marchioro Dos / Kaufmann, Camila / Rodrigues, Jonas de Almeida

    Brazilian oral research

    2024  Volume 38, Page(s) e009

    Abstract: This study was a randomized controlled clinical trial with two parallel arms and the objective was to compare the survival of resin modified glass ionomer (RMGIC) restorations in primary teeth using rubber dam or cotton roll isolation after a 30-month ... ...

    Abstract This study was a randomized controlled clinical trial with two parallel arms and the objective was to compare the survival of resin modified glass ionomer (RMGIC) restorations in primary teeth using rubber dam or cotton roll isolation after a 30-month follow-up period. Ninety-two children (mean age 6.8 ± 1.37) and 200 primary molars with occlusal or occluso-proximal cavitated dentin caries lesions were randomly assigned into two groups: cotton rolls and rubber dam. All lesions were restored using RMGIC (RIVA Light Cure) after selective caries removal. Restorative failure and lesion arrestment were evaluated by two independent, trained, and calibrated examiners through clinical and radiographic examinations. The Kaplan-Meier test was used to assess the survival of restorations and Cox regression was used to assess the association of risk factors with restorative failure. There was no significant difference in survival rates between groups (p = 0.17). Older age (HR = 2.81 [95%CI: 1.47-5.44]) and higher rate of gingival bleeding (HR = 0.47 [95%CI: 0.23-0.99]) were associated with restorative failure. No patient had painful symptoms, pulp outcomes, or radiographic changes compatible with lesion progression. The use of rubber dam isolation did not increase the survival rate of occlusal and occluso-proximal restorations using RMGIC in primary molars after 30 months of follow-up. Since the survival is not influenced by the type of isolation, the professional can safely choose the appropriate technique for each case, considering his experience and preferences, as well as those of the patient.
    MeSH term(s) Child ; Humans ; Child, Preschool ; Rubber Dams ; Dental Care ; Dental Caries/therapy ; Molar ; Acrylic Resins ; Silicon Dioxide
    Chemical Substances glass ionomer ; Acrylic Resins ; Silicon Dioxide (7631-86-9)
    Language English
    Publishing date 2024-01-05
    Publishing country Brazil
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2179332-3
    ISSN 1807-3107 ; 1806-8324 ; 1517-7491
    ISSN (online) 1807-3107
    ISSN 1806-8324 ; 1517-7491
    DOI 10.1590/1807-3107bor-2024.vol38.0009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A Rare Entity with an Impressive Appearance

    Mariana Santos / Sofia Brandão Miranda / Albina Silva Ramires / Ana Raquel Silva Raposo / Nicole Silva

    Gazeta Médica, Vol 1, Iss

    2023  Volume 1

    Keywords Hemangioma/diagnosis ; Infant ; Newborn ; Neoplasms ; Vascular Tissue ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher José de Mello Saúde
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: A Rare Entity with an Impressive Appearance

    Mariana Santos / Sofia Brandão Miranda / Albina Silva Ramires / Ana Raquel Silva Raposo / Nicole Silva

    Gazeta Médica, Vol 1, Iss

    2023  Volume 1

    Keywords Hemangioma/diagnosis ; Infant ; Newborn ; Neoplasms ; Vascular Tissue ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher José de Mello Saúde
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Communication skills training pilot programme after traumatic brain injury: short and medium-term benefits.

    Agrela, Nicole / Santos, Maria Emília / Guerreiro, Sandra

    Brain injury

    2021  Volume 35, Issue 3, Page(s) 304–314

    Abstract: ... ...

    Abstract Objective
    MeSH term(s) Brain Injuries, Traumatic ; Caregivers ; Communication ; Comprehension ; Humans ; Pilot Projects
    Language English
    Publishing date 2021-01-19
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 639115-1
    ISSN 1362-301X ; 0269-9052
    ISSN (online) 1362-301X
    ISSN 0269-9052
    DOI 10.1080/02699052.2021.1872096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Feasibility and acceptability of Narrative Exposure Therapy to treat individuals with PTSD who are homeless or vulnerably housed

    Nicole E. Edgar / Alexandria Bennett / Nicole Santos Dunn / Sarah E. MacLean / Simon Hatcher

    Pilot and Feasibility Studies, Vol 8, Iss 1, Pp 1-

    a pilot randomized controlled trial

    2022  Volume 16

    Abstract: Abstract Background Diagnosed PTSD rates in people who are homeless are more than double that of the general population, ranging between 21 and 53%. Complex PTSD (cPTSD) also appears to be more common than PTSD. One treatment option is Narrative Exposure ...

    Abstract Abstract Background Diagnosed PTSD rates in people who are homeless are more than double that of the general population, ranging between 21 and 53%. Complex PTSD (cPTSD) also appears to be more common than PTSD. One treatment option is Narrative Exposure Therapy (NET), a brief trauma-focused psychotherapy which attempts to place trauma within a narrative of the person’s life. Our primary aim was to assess the feasibility and acceptability of recruiting people to a randomized controlled trial (RCT) of NET alone compared to NET augmented by a genealogical assessment. We hypothesized that incorporating a genealogical assessment may be more effective than NET alone in a population with predominately complex PTSD. Methods This pilot RCT enrolled participants who were 18 years of age or older, currently homeless or vulnerably housed, and with active symptoms of PTSD. Participants were randomized to NET alone or NET plus a genealogical assessment. Rates of referral, consent, and retention were examined as part of feasibility. Demographic and clinical data were collected at baseline. Symptoms of PTSD, drug use, and housing status were re-assessed at follow-up visits. We conducted a thematic analysis of qualitative interviews of service providers involved in the study which explored barriers and facilitators of study participation. Results Twenty-two potential participants were referred to the study, with 15 consenting to participate. Of these, one was a screen failure and 14 were randomized equally to the treatment arms. One randomized participant was withdrawn for safety. Attrition occurred primarily prior to starting therapy. Once therapy began, retention was high with 80% of participants completing all six sessions. Seven participants completed all follow-up sessions. Service providers identified a clear need for the treatment and emphasized the importance of trauma-informed care, a desire to know more about NET, and more communication about the process of referral. Conclusion Recruiting participants who were ...
    Keywords Narrative Exposure Therapy ; Complex post-traumatic stress disorder ; Homelessness ; Trauma-informed care ; Medicine (General) ; R5-920
    Subject code 150
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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