Article ; Online: The impact of delayed access to COVID-19 vaccines in low- and lower-middle-income countries.
2023 Volume 10, Page(s) 1087138
Abstract: Introduction: A majority of low-income (LIC) and lower-middle-income countries (LMIC) were unable to achieve at least 10% population coverage during initial vaccine rollouts, despite the rapid development of the coronavirus disease 2019 (COVID-19) ... ...
| Abstract | Introduction: A majority of low-income (LIC) and lower-middle-income countries (LMIC) were unable to achieve at least 10% population coverage during initial vaccine rollouts, despite the rapid development of the coronavirus disease 2019 (COVID-19) vaccines. Nearly three years into this pandemic, evaluating the impact of inequities in vaccine access, uptake, and availability is long overdue. We hypothesized that a delay in receiving COVID-19 vaccines was associated with an increased toll on cumulative cases and mortality. Furthermore, this relationship was modified by the size of a country's economy. Methods: We performed an ecological study assessing these relationships, in which a country's economic standing was assessed by world bank income classification, gross domestic product based on the purchasing power parity (GDP PPP) per capita category, and crude GDP PPP. Results: Countries with the smallest economies reported first vaccination much later than larger economies on all three rankings, as much as 100 days longer. Among low-income countries, a one-day increase until the first vaccination was associated with a 1.92% (95% CI: 0.100, 3.87) increase in cumulative cases when compared to high-income countries ( Conclusion: Economic standing modified the effects of delayed access to COVID-19 vaccination on cumulative cases and mortality, in which LMICs tended to fare worse in outcomes than high-income countries despite the eventual rollout of vaccines. These findings highlight the importance of prioritizing equitable and timely access to COVID-19 vaccines across all countries, irrespective of economic size. Future studies should examine the impacts that vaccine inequities had on local transmission dynamics. |
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| MeSH term(s) | Humans ; COVID-19 Vaccines ; Developing Countries ; COVID-19/epidemiology ; COVID-19/prevention & control ; Vaccination ; Vaccines |
| Chemical Substances | COVID-19 Vaccines ; Vaccines |
| Language | English |
| Publishing date | 2023-01-12 |
| Publishing country | Switzerland |
| Document type | Journal Article |
| ZDB-ID | 2711781-9 |
| ISSN | 2296-2565 ; 2296-2565 |
| ISSN (online) | 2296-2565 |
| ISSN | 2296-2565 |
| DOI | 10.3389/fpubh.2022.1087138 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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