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  1. Book ; Online ; E-Book: Equipment for respiratory care

    Volsko, Teresa A. / Chatburn, Robert L. / El-Khatib, Mohamad F.

    2022  

    Author's details Teresa A. Volsko, Robert L. Chatburn, Mohamad F. El-Khatib
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (1713 Seiten), Illustrationen
    Edition Second edition
    Publisher Jones & Bartlett Learning
    Publishing place Burlington, MA
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020709634
    ISBN 978-1-284-19623-8 ; 9781284196221 ; 1-284-19623-2 ; 1284196224
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Ratio of oxygen saturation index for predicting high-flow nasal cannula outcomes in emergency department for COVID-19 patients with severe hypoxemia: A retrospective study.

    Karam, Cynthia / Oseili, Ahmad / Shebbo, Fadia M / Fakih, Mohamad / El-Khatib, Mohamad F

    Turkish journal of emergency medicine

    2024  Volume 24, Issue 1, Page(s) 41–47

    Abstract: Objectives: High-flow nasal cannula (HFNC) oxygen therapy has been used as an initial ventilatory support for coronavirus disease 2019 (COVID-19) patients with mixed levels of acute hypoxemic respiratory failure (AHRF). However, the effectiveness of ... ...

    Abstract Objectives: High-flow nasal cannula (HFNC) oxygen therapy has been used as an initial ventilatory support for coronavirus disease 2019 (COVID-19) patients with mixed levels of acute hypoxemic respiratory failure (AHRF). However, the effectiveness of HFNC when used as initial ventilatory support in COVID-19 patients with severe AHRF exclusively is not well documented. Ratio of oxygen saturation (ROX) index (ROX = [SpO
    Methods: Retrospective study in 67 COVID-19 patients with severe AHRF receiving HFNC in the emergency department at a tertiary care academic medical center. ROX index was determined at 0, 2, 6, 12, and 24 h of HFNC onset. The need to escalate to noninvasive or invasive ventilatory support was documented. The receiver operating characteristic curves were performed and areas under the curves (AUCs) were calculated to evaluate the accuracy of ROX index for differentiating between patients who will succeed or fail HFNC therapy.
    Results: HFNC therapy was successful in 19 patients (28.1%) and failed in 48 patients (71.6%). ROX index after 6 h of HFNC initiation had the best predictive capacity for the outcome of HFNC therapy (AUC = 0.78). ROX index >4.4 at 6 h of HFNC onset was significantly associated with HFNC success/failure.
    Conclusion: ROX index at 6 h after initiating HFNC therapy in COVID-19 patients with severe AHRF has a good predictive capacity for HFNC success/failure.
    Language English
    Publishing date 2024-01-08
    Publishing country India
    Document type Journal Article
    ISSN 2452-2473
    ISSN 2452-2473
    DOI 10.4103/tjem.tjem_159_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effect of Ventilator Settings on Mechanical Power During Simulated Mechanical Ventilation of Patients With ARDS.

    El-Khatib, Mohamad F / Zeinelddine, Salah M / HajAli, Thuraya H / Rizk, Marwan / van der Staay, Matthias / Chatburn, Robert L

    Respiratory care

    2024  Volume 69, Issue 4, Page(s) 449–462

    Abstract: Background: In recent years, mechanical power (MP) has emerged as an important concept that can significantly impact outcomes from mechanical ventilation. Several individual components of ventilatory support such as tidal volume (V: Methods: We used ... ...

    Abstract Background: In recent years, mechanical power (MP) has emerged as an important concept that can significantly impact outcomes from mechanical ventilation. Several individual components of ventilatory support such as tidal volume (V
    Methods: We used an interactive mathematical model of ventilator output during volume control ventilation (VCV) with either constant inspiratory flow (VCV-CF) or descending ramp inspiratory flow, as well as pressure control ventilation (PCV). MP values were determined for simulated subjects with mild, moderate, and severe ARDS; and whenever MP > 17 J/min, V
    Results: VCV-CF always resulted in the lowest MPs while PCV resulted in highest MPs. Reductions in V
    Conclusions: VCV-CF resulted in the lowest MP. V
    MeSH term(s) Humans ; Respiration, Artificial/methods ; Ventilators, Mechanical ; Lung ; Tidal Volume ; Respiratory Distress Syndrome/therapy
    Language English
    Publishing date 2024-03-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.11470
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Incorporating ventilatory support parameters into the PaO

    El-Khatib, Mohamad F / BouAkl, Imad J / Hallal, Ali H

    Annals of intensive care

    2021  Volume 11, Issue 1, Page(s) 137

    Language English
    Publishing date 2021-09-22
    Publishing country Germany
    Document type Letter
    ZDB-ID 2617094-2
    ISSN 2110-5820
    ISSN 2110-5820
    DOI 10.1186/s13613-021-00926-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Sleep quality in survivors of critical illness: practical shortcomings unresolved.

    El-Khatib, Mohamad F / Esquinas, Antonio M

    Sleep & breathing = Schlaf & Atmung

    2018  Volume 23, Issue 2, Page(s) 583–584

    MeSH term(s) Critical Illness ; Humans ; Intensive Care Units ; Sleep ; Sleep Apnea, Obstructive ; Survivors
    Language English
    Publishing date 2018-09-15
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 1500381-4
    ISSN 1522-1709 ; 1520-9512
    ISSN (online) 1522-1709
    ISSN 1520-9512
    DOI 10.1007/s11325-018-1719-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: High-flow nasal cannula oxygen therapy during hypoxemic respiratory failure.

    El-Khatib, Mohamad F

    Respiratory care

    2012  Volume 57, Issue 10, Page(s) 1696–1698

    MeSH term(s) Critical Care ; Female ; Humans ; Hypoxia/therapy ; Male ; Oxygen Inhalation Therapy/methods ; Patient Preference ; Respiratory Insufficiency/therapy
    Language English
    Publishing date 2012-10
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 603252-7
    ISSN 0020-1324 ; 0098-9142
    ISSN 0020-1324 ; 0098-9142
    DOI 10.4187/respcare.02072
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Validation of the Arabic Severe Respiratory Insufficiency Questionnaire.

    Alawieh, Marwan F / Bzeih, Rania N / El-Khatib, Mohamad F / Sibai, Abla M / Ghandour, Lilian A / Zeineldine, Salah M

    BMC pulmonary medicine

    2021  Volume 21, Issue 1, Page(s) 315

    Abstract: Background/objectives: Assessment of Health-Related Quality of Life (HRQL) in patients with chronic respiratory insufficiency requiring Home Mechanical Ventilation (HMV) requires a valid measurement tool. The Severe Respiratory Insufficiency (SRI) ... ...

    Abstract Background/objectives: Assessment of Health-Related Quality of Life (HRQL) in patients with chronic respiratory insufficiency requiring Home Mechanical Ventilation (HMV) requires a valid measurement tool. The Severe Respiratory Insufficiency (SRI) questionnaire, originally developed in German, has been translated into different languages and tested in different contexts, but has so far not been in use in Arabic-speaking populations. The objective of this study is to validate the Arabic version of the SRI questionnaire in a sample of Arabic-speaking patients from Lebanon.
    Methods: Following forward/backward translations, the finalized Arabic version was administered to 149 patients (53 males-96 females, age 69.80 ± 10 years) receiving HMV. Patients were recruited from outpatient clinics and visited at home. The Arabic SRI and the 36-Item Short-Form Health Survey (SF-36) were administered, in addition to questions on sociodemographics and medical history. Exploratory Factor Analysis (EFA) was used to explore dimensionality; internal consistency reliability of the unidimensional scale and its subscales was assessed using Cronbach's alpha. External nomological validity was examined by assessing the correlation between the SRI and SF-36 scores.
    Results: The 49-item Arabic SRI scale showed a high internal consistency reliability (Cronbach alpha for the total scale was 0.897 and ranged between 0.73 and 0.87 for all subscales). Correlations between the SF-36-Mental Health Component MHC and SF-36-Physical Health Component with SRI-Summary Scale were 0.57 and 0.66, respectively, with higher correlations observed between the SF-36 and specific sub-scales such as the Physical Functioning and the Social Functioning subscales [r = 0.81 and r = 0.74 (P < 0.01), respectively].
    Conclusion and recommendations: The Arabic SRI is a reliable and valid tool for assessing HRQL in patients with chronic respiratory insufficiency receiving home mechanical ventilation.
    MeSH term(s) Aged ; Cross-Cultural Comparison ; Female ; Germany ; Home Care Services, Hospital-Based ; Humans ; Lebanon ; Male ; Middle Aged ; Psychometrics ; Quality of Life ; Reproducibility of Results ; Respiration, Artificial ; Respiratory Insufficiency/therapy ; Surveys and Questionnaires ; Translations
    Language English
    Publishing date 2021-10-11
    Publishing country England
    Document type Journal Article ; Validation Study
    ZDB-ID 2059871-3
    ISSN 1471-2466 ; 1471-2466
    ISSN (online) 1471-2466
    ISSN 1471-2466
    DOI 10.1186/s12890-021-01644-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Comparison of the Oxygenation Factor and the Oxygenation Ratio in Subjects With ARDS.

    El-Khatib, Mohamad F / Bouakl, Imad J / Ayoub, Chakib M / Chatburn, Robert L / Farhat, Hatem / Msheik, Mayyas / Fakih, Mohamad H / Hallal, Ali H

    Respiratory care

    2020  Volume 65, Issue 12, Page(s) 1874–1882

    Abstract: Background: The oxygenation ratio (ie, [Formula: see text]/[Formula: see text]) remains the most commonly used index for assessing oxygenation and disease severity in patients with acute ARDS. However, the oxygenation ratio does not account for ... ...

    Abstract Background: The oxygenation ratio (ie, [Formula: see text]/[Formula: see text]) remains the most commonly used index for assessing oxygenation and disease severity in patients with acute ARDS. However, the oxygenation ratio does not account for mechanical ventilation settings. We hypothesized that the oxygenation factor (ie, oxygenation ratio/mean airway pressure) is superior to the oxygenation ratio in reflecting oxygenation in patients with ARDS and results in a different classification of ARDS severity.
    Methods: In 150 subjects with ARDS (50 severe, 50 moderate, and 50 mild), arterial blood gas, mean airway pressure, static lung compliance, driving pressure, and mechanical power were obtained. The oxygenation ratio and the oxygenation factor were then calculated. Receiver operating characteristic curves were constructed for oxygenation ratio and oxygenation factor at lung compliance > 40 mL/cm H
    Results: Areas under the receiver operating characteristic curves for the oxygenation factor were significantly higher than for the oxygenation ratio. Reclassification of ARDS severity using the oxygenation factor did not affect subjects classified as having severe ARDS per the oxygenation ratio. However, 52% of subjects with moderate ARDS per the oxygenation ratio criteria were reclassified as either severe (25 subjects) or mild ARDS (1 subject) on the basis of oxygenation factor criteria. Also, 54% of subjects with mild ARDS per the oxygenation ratio criteria were reclassified as severe (4 subjects), moderate (21 subjects), or non-ARDS (2 subjects) on the basis of oxygenation factor criteria.
    Conclusions: The oxygenation factor was a superior ARDS oxygenation index compared to the oxygenation ratio and should be considered as a substitute criteria for classification of the severity of ARDS. (ClinicalTrials.gov registration NCT03946189.).
    MeSH term(s) Blood Gas Analysis ; Humans ; Lung ; Lung Compliance ; Oxygen ; Respiration, Artificial ; Respiratory Distress Syndrome/therapy
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2020-07-21
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.07669
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: In Vitro Anti-Diabetic, Anti-Inflammatory, Antioxidant Activities and Toxicological Study of Optimized

    Syed Mohamad, Sharifah Nurul Akilah / Khatib, Alfi / So'ad, Siti Zaiton Mat / Ahmed, Qamar Uddin / Ibrahim, Zalikha / Nipun, Tanzina Sharmin / Humaryanto, Humaryanto / AlAjmi, Mohamed F / Khalifa, Shaden A M / El-Seedi, Hesham R

    Pharmaceuticals (Basel, Switzerland)

    2023  Volume 16, Issue 12

    Abstract: Psychotria ... ...

    Abstract Psychotria malayana
    Language English
    Publishing date 2023-12-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph16121692
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Aflatoxins and Ochratoxin A in Tea Sold in Lebanon: Effects of Type, Packaging, and Origin.

    Hassan, Hussein F / Tashani, Hadeel / Ballouk, Farah / Daou, Rouaa / El Khoury, André / Abiad, Mohamad G / AlKhatib, Ali / Hassan, Mahdi / El Khatib, Sami / Dimassi, Hani

    International journal of environmental research and public health

    2023  Volume 20, Issue 16

    Abstract: Tea is among the oldest and most-known beverages around the world, and it has many flavors and types. Tea can be easily contaminated in any of its production steps, especially with mycotoxins that are produced particularly in humid and warm environments. ...

    Abstract Tea is among the oldest and most-known beverages around the world, and it has many flavors and types. Tea can be easily contaminated in any of its production steps, especially with mycotoxins that are produced particularly in humid and warm environments. This study aims to examine the level of ochratoxin A (OTA) and total aflatoxin (AF) contamination in black and green tea sold in Lebanon, evaluate its safety compared to international standards, and assess the effect of different variables on the levels of OTA and AFs. For this, the Lebanese market was screened and all tea brands (
    MeSH term(s) Aflatoxins ; Lebanon ; Product Packaging ; Tea
    Chemical Substances ochratoxin A (1779SX6LUY) ; Aflatoxins ; Tea
    Language English
    Publishing date 2023-08-10
    Publishing country Switzerland
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20166556
    Database MEDical Literature Analysis and Retrieval System OnLINE

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