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  1. Article ; Online: What is the comparative efficacy of negative-pressure wound therapy vs alternate temporary abdominal closure techniques in open abdominal wounds?

    Henteleff, Harry J / Parry, Neil G / Burlew, Clay Cothren

    Journal of the American College of Surgeons

    2014  Volume 218, Issue 6, Page(s) 1251–1253

    MeSH term(s) Abdominal Injuries/mortality ; Abdominal Injuries/surgery ; Female ; Humans ; Male ; Negative-Pressure Wound Therapy/methods ; Surgical Wound Infection/prevention & control ; Wound Healing/physiology
    Language English
    Publishing date 2014-06
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 1181115-8
    ISSN 1879-1190 ; 1072-7515
    ISSN (online) 1879-1190
    ISSN 1072-7515
    DOI 10.1016/j.jamcollsurg.2014.03.022
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  2. Article ; Online: Cost-effectiveness of bariatric surgery for severely obese adults with diabetes.

    Henteleff, Harry J / Birch, Daniel W / Hallowell, Peter T

    Canadian journal of surgery. Journal canadien de chirurgie

    2013  Volume 56, Issue 5, Page(s) 353–355

    MeSH term(s) Humans ; Internship and Residency/trends ; Models, Educational ; Teaching/methods
    Language English
    Publishing date 2013-09-25
    Publishing country Canada
    Document type Journal Article ; Comment
    ZDB-ID 410651-9
    ISSN 1488-2310 ; 0008-428X
    ISSN (online) 1488-2310
    ISSN 0008-428X
    DOI 10.1503/cjs.020713
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  3. Article ; Online: Comparative effectiveness of magnetic resonance imaging in breast cancer.

    Henteleff, Harry J A / Hunt, Kelly K / Quan, May Lynn

    Journal of the American College of Surgeons

    2012  Volume 215, Issue 6, Page(s) 894–6; discussion 895–6

    Language English
    Publishing date 2012-11-14
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 1181115-8
    ISSN 1879-1190 ; 1072-7515
    ISSN (online) 1879-1190
    ISSN 1072-7515
    DOI 10.1016/j.jamcollsurg.2012.09.006
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  4. Article ; Online: CAGS and ACS evidence based reviews in surgery. Guidelines for the management of Barrett esophagus with high-grade dysplasia?

    Henteleff, Harry J / Ellsmere, James C / Rizk, Nabil

    Canadian journal of surgery. Journal canadien de chirurgie

    2011  Volume 54, Issue 5, Page(s) 352–354

    Language English
    Publishing date 2011-09-21
    Publishing country Canada
    Document type Comment ; Journal Article
    ZDB-ID 410651-9
    ISSN 1488-2310 ; 0008-428X
    ISSN (online) 1488-2310
    ISSN 0008-428X
    DOI 10.1503/cjs.027111
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  5. Article ; Online: Ten-year follow-up of a province-wide cohort of surgical lung cancer patients in Nova Scotia.

    Wong, Daniel R / Henteleff, Harry J

    Canadian journal of surgery. Journal canadien de chirurgie

    2008  Volume 51, Issue 4, Page(s) 257–262

    Abstract: Background: After a diagnosis of lung carcinoma, survival is poor for all patients. We sought to assess 10-year survival and predictors of outcome after surgery for lung cancer in Nova Scotia.: Methods: We identified all patients n = 130) undergoing ... ...

    Abstract Background: After a diagnosis of lung carcinoma, survival is poor for all patients. We sought to assess 10-year survival and predictors of outcome after surgery for lung cancer in Nova Scotia.
    Methods: We identified all patients n = 130) undergoing resection for lung cancer in Nova Scotia in 1994 from the Nova Scotia Cancer Registry and hospital charts and followed them prospectively for 10 years. We used Cox proportional hazards modelling to identify predictors of survival.
    Results: The patients' mean age at operation was 67.7 (standard deviation [SD] 8.2) years, and 70% of the patients were men. Most of the operations n = 80, 61.5%) were performed in Halifax, and adenocarcinoma n = 55, 42.3%) was the most common histologic type. At the time of surgery, 66.9% of the cases were stage 1, 20.0% were stage 2 and 13.1% were stage 3. Survival at 5 and 10 years was 34% and 13%, respectively. Age of 70 years or older (hazard ratio [HR] 1.79, 95% confidence interval [CI] 1.20-2.68), large cell carcinoma (HR 2.27, 95% CI 1.31-3.94) and stage 3 cancer (HR 2.21, 95% CI 1.25-3.90) were significant independent predictors of survival. Hospital site was not associated with any difference in survival (p = 0.66), although there was a trend toward differential rates of lymph node sampling across sites (p = 0.06). The presence of node sampling was associated with improved survival in a separate multivariate model (HR 0.51, 95% CI 0.29-0.89).
    Conclusion: Actuarial survival after resection of lung carcinoma in Nova Scotia in 1994 was 34% at 5 years and 13% after 10 years. Age, stage and histology are independent predictors of survival; lymph node sampling was associated with greater survival.
    MeSH term(s) Aged ; Diagnosis, Differential ; Female ; Follow-Up Studies ; Humans ; Lung Neoplasms/diagnosis ; Lung Neoplasms/epidemiology ; Lung Neoplasms/surgery ; Male ; Nova Scotia/epidemiology ; Pneumonectomy/methods ; Prognosis ; Retrospective Studies ; Risk Factors ; Survival Rate/trends ; Time Factors
    Language English
    Publishing date 2008-08
    Publishing country Canada
    Document type Comparative Study ; Journal Article ; Multicenter Study
    ZDB-ID 410651-9
    ISSN 1488-2310 ; 0008-428X
    ISSN (online) 1488-2310
    ISSN 0008-428X
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  6. Article: Evidence-based review of the surgical management of hyperhidrosis.

    Henteleff, Harry J / Kalavrouziotis, Dimitri

    Thoracic surgery clinics

    2008  Volume 18, Issue 2, Page(s) 209–216

    Abstract: The great majority of the currently available evidence supporting sympathectomy for primary hyperhidrosis is observational, coming from a variety of prospective and restrospective clinical series as well as comparative studies. A cumulative experience in ...

    Abstract The great majority of the currently available evidence supporting sympathectomy for primary hyperhidrosis is observational, coming from a variety of prospective and restrospective clinical series as well as comparative studies. A cumulative experience in over 6000 patients suggests that ETS is a safe, reproducible, and effective procedure, and most patients are satisfied with the results of the surgery. The currently available experimental data comes from clinical trials that compared alternative levels of sympathetic chain disruption; these trials speak only to the relative merits of one surgical technique over another and do not provide an assessment of the overall impact of surgery in the general population of patients with primary hyperhidrosis. Furthermore, it is difficult to compare series and generalizability is compromised by a lack of uniform definitions and measures at both the exposure and outcome levels. There is marked heterogeneity with respect to study population and entry criteria, with significant variability of site and severity of excess sweating as well as the degree of preoperative conservative management of hyperhidrosis before surgical referral. Also the operative approach varies widely among studies, and the optimal procedure remains elusive: unilateral versus staged nonsimultaneous bilateral versus concomitant bilateral sympathectomy; ganglionic resection versus ablation using electrocoagulation or harmonic scalpel; clipping of the chain to maintain reversibility in the event of intolerable symptoms versus permanent disruption. In addition, the lack of uniform outcome measures makes these data difficult to interpret, and standardized metrics of surgical results are necessary, such as objective quantification of sweating by gravimetry or use of the SF-36 Health Survey Questionnaire as an estimate of patient quality of life. A multicenter, adequately powered, randomized controlled trial comparing surgical to medical management of hyperhidrosis is unlikely given the current enthusiasm for same-day thoracoscopic sympathectomy among surgeons, a largely positive literature replete with encouraging results, and well-informed hyperhidrosis patients who want to be cured of a socially debilitating illness. Future clinical trials in this area will likely compare surgical techniques. For such comparisons, procedures must be standardized and outcome measures validated for both symptoms of the disease and surgical complications. Finally, the studies must have large numbers of patients and adequate long-term follow-up if they are to detect differences in results among procedures with very high technical success rates.
    MeSH term(s) Adult ; Humans ; Hyperhidrosis/surgery ; Quality of Life ; Sympathectomy ; Thoracoscopy ; Treatment Outcome
    Language English
    Publishing date 2008-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2149218-9
    ISSN 1558-5069 ; 1547-4127
    ISSN (online) 1558-5069
    ISSN 1547-4127
    DOI 10.1016/j.thorsurg.2008.01.008
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  7. Article ; Online: Universal screening for methicillin-resistant Staphylococcus aureus in surgical patients.

    Henteleff, Harry J / Barie, Philip S / Hamilton, Stewart M

    Journal of the American College of Surgeons

    2010  Volume 211, Issue 6, Page(s) 833–835

    Language English
    Publishing date 2010-12
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 1181115-8
    ISSN 1879-1190 ; 1072-7515
    ISSN (online) 1879-1190
    ISSN 1072-7515
    DOI 10.1016/j.jamcollsurg.2010.09.007
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  8. Article ; Online: Endoscopic mucosal resection for high-grade dysplasia and intramucosal carcinoma: a Canadian experience.

    Yamashita, Denise Tami / Li, Chao / Bethune, Drew / Henteleff, Harry / Ellsmere, James

    Canadian journal of surgery. Journal canadien de chirurgie

    2017  Volume 60, Issue 2, Page(s) 129–133

    Abstract: Background: Endoscopic mucosal resection (EMR) is increasingly being used as a first-line treatment for Barrett esophagus (BE) with high-grade dysplasia (HGD) and intramucosal adenocarcinoma (IMC). We reviewed our experience with endoscopic treatment of ...

    Abstract Background: Endoscopic mucosal resection (EMR) is increasingly being used as a first-line treatment for Barrett esophagus (BE) with high-grade dysplasia (HGD) and intramucosal adenocarcinoma (IMC). We reviewed our experience with endoscopic treatment of BE with HGD and IMC at our institution with respect to eradication rates, complications and long-term recurrence.
    Methods: We performed a single-centre retrospective review of all patients referred between October 2010 and August 2014 for EMR with dysplastic BE or IMC. We performed EMR using a cap-fitted endoscope, and the procedure was repeated every 3 months until eradication or progression of disease.
    Results: A total of 28 patients were identified: 16 with dysplastic BE (14 HGD, 1 low-grade dysplasia, 1 intermediate dysplasia) and 12 with IMC. Complete eradication of HGD was achieved in 11 of 14 (79%) patients. Three of 12 (25%) patients initially referred with suspected IMC were found to have invasive adenocarcinoma on EMR. Eradication was successful in 8 of 9 (89%) patients with true IMC, with 1 patient progressing to salvage esophagectomy. Complications occurred in 2 of 28 (7%) patients; both had esophageal strictures managed with dilatation. Median duration of follow-up was 371 days.
    Conclusion: Our experience supports the safety of EMR as a first-line treatment for patients with BE with dysplasia and IMC in early short-term follow-up.
    MeSH term(s) Adenocarcinoma/surgery ; Aged ; Aged, 80 and over ; Barrett Esophagus/surgery ; Canada ; Endoscopic Mucosal Resection/methods ; Esophageal Neoplasms/surgery ; Female ; Humans ; Male ; Middle Aged ; Outcome Assessment, Health Care ; Retrospective Studies
    Language English
    Publishing date 2017-03-23
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 410651-9
    ISSN 1488-2310 ; 0008-428X
    ISSN (online) 1488-2310
    ISSN 0008-428X
    DOI 10.1503/cjs.013515
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  9. Article ; Online: Endoscopic mucosal resection versus esophagectomy for intramucosal adenocarcinoma in the setting of barrett's esophagus.

    Li, Chao / Yamashita, Denise Tami / Hawel, Jeffrey David / Bethune, Drew / Henteleff, Harry / Ellsmere, James

    Surgical endoscopy

    2017  Volume 31, Issue 10, Page(s) 4211–4216

    Abstract: Background: Esophagectomy has been the standard of care for patients with intramucosal adenocarcinoma (IMC) in the setting of Barrett's esophagus. It is, however, associated with significant post-operative morbidity and mortality. Endoscopic mucosal ... ...

    Abstract Background: Esophagectomy has been the standard of care for patients with intramucosal adenocarcinoma (IMC) in the setting of Barrett's esophagus. It is, however, associated with significant post-operative morbidity and mortality. Endoscopic mucosal resection (EMR) offers a minimally invasive approach with lesser morbidity. This study investigates the transition from esophagectomy to EMR for IMC with respect to eradication rates, post-operative morbidity, and long-term survival.
    Methods: Patients diagnosed with IMC from 2005 to 2013 were identified retrospectively. Beginning in 2009, preferred initial therapy for IMC transitioned from esophagectomy to EMR. Esophagectomy was performed either through a transthoracic or transhiatal technique. EMR was repeated until resolution of IMC on pathology or progression of disease. Continuous data are expressed as mean (SD) and analyzed using Student's t test. Categorical data are presented as number (%) and analyzed using Fisher's exact test.
    Results: We identified 23 patients; 12 patients underwent esophagectomy and 11 patients underwent EMR as initial therapy. Patients were similar with respects to age, gender, and comorbidity index. Most tumors arose from short segment (vs long segment) Barrett's (esophagectomy: 9 (75%) vs. EMR: 10 (91%), p = 0.59) and one patient in each group had superficial invasion into the submucosa (T1sm1), the remainder having mucosal disease. Esophagectomy was associated with 7 (58%) minor complications and 2 (17%) major complications (respiratory failure, anastomotic leak), whereas there were no complications related to EMR (p < 0.01). EMR successfully eradicated IMC in 10 patients (91%) with one progressing to esophagectomy. Patients required 2 (1) endoscopies to achieve eradication. There was one mortality in each group on long-term follow-up (log-rank test, p = 0.62).
    Conclusions: EMR was successful in eradicating IMC in 10/11 patients with similar long-term recurrence and mortality to esophagectomy patients. Patients with IMC may benefit from EMR as initial therapy by obviating the need for a complex and morbid operation.
    MeSH term(s) Adenocarcinoma/pathology ; Adenocarcinoma/surgery ; Aged ; Barrett Esophagus/complications ; Barrett Esophagus/pathology ; Barrett Esophagus/surgery ; Disease Progression ; Endoscopic Mucosal Resection/methods ; Esophageal Neoplasms/pathology ; Esophageal Neoplasms/surgery ; Esophagectomy/methods ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Neoplasm Recurrence, Local/surgery ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2017
    Publishing country Germany
    Document type Comparative Study ; Journal Article
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-017-5479-z
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  10. Article: Canadian Association of General Surgeons Evidence Based Reviews in Surgery. 6. "GERD" as a risk factor for esophageal cancer. Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma.

    Henteleff, Harry J A / Darling, Gail

    Canadian journal of surgery. Journal canadien de chirurgie

    2003  Volume 46, Issue 3, Page(s) 208–210

    Language English
    Publishing date 2003-06
    Publishing country Canada
    Document type Comment ; Journal Article
    ZDB-ID 410651-9
    ISSN 0008-428X
    ISSN 0008-428X
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