LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 465

Search options

  1. Book ; Online: Continued Fascination - A Tribute to a Giant in Immunology, Dr. William E. Paul

    Zhu, Jinfang / Milner, Joshua D.

    2019  

    Keywords Medicine ; Immunology ; William E. Paul ; Interleukin-4 ; T cell differentiation ; B cell activation ; Immune homeostasis ; Mast Cells
    Size 1 electronic resource (147 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021231459
    ISBN 9782889458769 ; 2889458768
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: A pathway linking atopic dermatitis to skin microbes.

    Zhu, Jinfang

    Cell host & microbe

    2024  Volume 32, Issue 2, Page(s) 154–155

    Abstract: Interactions between microbiota and host skin have an important impact on cutaneous immunity and inflammation. In this issue of Cell Host & Microbe, Cha et al. report that skin commensal bacteria-mediated priming of group 2 innate lymphoid cells in early ...

    Abstract Interactions between microbiota and host skin have an important impact on cutaneous immunity and inflammation. In this issue of Cell Host & Microbe, Cha et al. report that skin commensal bacteria-mediated priming of group 2 innate lymphoid cells in early life predisposes the mice to atopic dermatitis-like inflammation in adulthood.
    MeSH term(s) Mice ; Animals ; Dermatitis, Atopic ; Immunity, Innate ; Lymphocytes ; Skin ; Inflammation/metabolism
    Language English
    Publishing date 2024-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2278004-X
    ISSN 1934-6069 ; 1931-3128
    ISSN (online) 1934-6069
    ISSN 1931-3128
    DOI 10.1016/j.chom.2024.01.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6578: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Mysterious ILC2 tissue adaptation.

    Zhu, Jinfang

    Nature immunology

    2018  Volume 19, Issue 10, Page(s) 1042–1044

    MeSH term(s) Interleukin-13 ; Lymphocytes
    Chemical Substances Interleukin-13
    Language English
    Publishing date 2018-11-20
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2016987-5
    ISSN 1529-2916 ; 1529-2908
    ISSN (online) 1529-2916
    ISSN 1529-2908
    DOI 10.1038/s41590-018-0214-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5294: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 42: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Innate Lymphoid Cells and Intestinal Inflammatory Disorders

    Mingzhu Zheng / Jinfang Zhu

    International Journal of Molecular Sciences, Vol 23, Iss 1856, p

    2022  Volume 1856

    Abstract: Innate lymphoid cells (ILCs) are a population of lymphoid cells that do not express T cell or B cell antigen-specific receptors. They are largely tissue-resident and enriched at mucosal sites to play a protective role against pathogens. ILCs mimic the ... ...

    Abstract Innate lymphoid cells (ILCs) are a population of lymphoid cells that do not express T cell or B cell antigen-specific receptors. They are largely tissue-resident and enriched at mucosal sites to play a protective role against pathogens. ILCs mimic the functions of CD4 T helper (Th) subsets. Type 1 innate lymphoid cells (ILC1s) are defined by the expression of signature cytokine IFN-γ and the master transcription factor T-bet, involving in the type 1 immune response; ILC2s are characterized by the expression of signature cytokine IL-5/IL-13 and the master transcription factor GATA3, participating in the type 2 immune response; ILC3s are RORγt-expressing cells and are capable of producing IL-22 and IL-17 to maintain intestinal homeostasis. The discovery and investigation of ILCs over the past decades extends our knowledge beyond classical adaptive and innate immunology. In this review, we will focus on the roles of ILCs in intestinal inflammation and related disorders.
    Keywords ILC1 ; ILC2 ; ILC3 ; intestinal inflammation ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Subject code 570
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article ; Online: Innate Lymphoid Cells and Intestinal Inflammatory Disorders.

    Zheng, Mingzhu / Zhu, Jinfang

    International journal of molecular sciences

    2022  Volume 23, Issue 3

    Abstract: Innate lymphoid cells (ILCs) are a population of lymphoid cells that do not express T cell or B cell antigen-specific receptors. They are largely tissue-resident and enriched at mucosal sites to play a protective role against pathogens. ILCs mimic the ... ...

    Abstract Innate lymphoid cells (ILCs) are a population of lymphoid cells that do not express T cell or B cell antigen-specific receptors. They are largely tissue-resident and enriched at mucosal sites to play a protective role against pathogens. ILCs mimic the functions of CD4 T helper (Th) subsets. Type 1 innate lymphoid cells (ILC1s) are defined by the expression of signature cytokine IFN-γ and the master transcription factor T-bet, involving in the type 1 immune response; ILC2s are characterized by the expression of signature cytokine IL-5/IL-13 and the master transcription factor GATA3, participating in the type 2 immune response; ILC3s are RORγt-expressing cells and are capable of producing IL-22 and IL-17 to maintain intestinal homeostasis. The discovery and investigation of ILCs over the past decades extends our knowledge beyond classical adaptive and innate immunology. In this review, we will focus on the roles of ILCs in intestinal inflammation and related disorders.
    MeSH term(s) Animals ; Gastroenteritis/immunology ; Gene Expression Regulation ; Humans ; Immunity, Innate ; Interferon-gamma/metabolism ; Interleukin-17/metabolism ; Interleukins/metabolism ; Lymphocytes/immunology ; Nuclear Receptor Subfamily 1, Group F, Member 3/metabolism ; T-Box Domain Proteins/metabolism ; Interleukin-22
    Chemical Substances IFNG protein, human ; Interleukin-17 ; Interleukins ; Nuclear Receptor Subfamily 1, Group F, Member 3 ; RORC protein, human ; T-Box Domain Proteins ; T-box transcription factor TBX21 ; Interferon-gamma (82115-62-6)
    Language English
    Publishing date 2022-02-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms23031856
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: T Helper Cell Differentiation, Heterogeneity, and Plasticity.

    Zhu, Jinfang

    Cold Spring Harbor perspectives in biology

    2018  Volume 10, Issue 10

    Abstract: Naïve CD4 T cells, on activation, differentiate into distinct T helper (Th) subsets that produce lineage-specific cytokines. By producing unique sets of cytokines, effector Th subsets play critical roles in orchestrating immune responses to a variety of ... ...

    Abstract Naïve CD4 T cells, on activation, differentiate into distinct T helper (Th) subsets that produce lineage-specific cytokines. By producing unique sets of cytokines, effector Th subsets play critical roles in orchestrating immune responses to a variety of infections and are involved in the pathogenesis of many inflammatory diseases including autoimmunity, allergy, and asthma. The differentiation of Th cells relies on the strength of T-cell receptor (TCR) signaling and signals triggered by polarizing cytokines that activate and/or up-regulate particular transcription factors. Several lineage-specific master transcription factors dictate Th cell fates and functions. Although these master regulators cross-regulate each other, their expression can be dynamic. Sometimes, they are even coexpressed, resulting in massive Th-cell heterogeneity and plasticity. Similar regulation mediated by these master regulators is also found in innate lymphoid cells (ILCs) that are innate counterparts of Th cells.
    MeSH term(s) Animals ; Cell Differentiation/physiology ; Gene Expression Regulation ; Humans ; Inflammation ; Lymphocyte Activation ; T-Lymphocytes, Helper-Inducer/classification ; T-Lymphocytes, Helper-Inducer/physiology
    Language English
    Publishing date 2018-10-01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, N.I.H., Intramural ; Review
    ISSN 1943-0264
    ISSN (online) 1943-0264
    DOI 10.1101/cshperspect.a030338
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: A case of lupus erythematosus tumidus misdiagnosed as erysipelas

    Qing Zhu / Chenglin Zhu / Jinfang Zhang / Yuli Zhang / Guoqiang Zhang

    European Journal of Inflammation, Vol

    2023  Volume 21

    Abstract: A patient presented with erythema and oedema on the right eyelid, malar region and left thigh with pruritus and pain. She was diagnosed with erysipelas and had been treated with anti-inflammatory drugs, but the symptoms did not improve. Laboratory ... ...

    Abstract A patient presented with erythema and oedema on the right eyelid, malar region and left thigh with pruritus and pain. She was diagnosed with erysipelas and had been treated with anti-inflammatory drugs, but the symptoms did not improve. Laboratory investigation and biopsy showed that she was consistent with lupus erythematosus tumidus. It's a typical and rare diease relatively.
    Keywords Medicine ; R
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article: Seventeen-Year Journey Working With a Master.

    Zhu, Jinfang

    Frontiers in immunology

    2018  Volume 9, Page(s) 960

    Abstract: It had been a great honor for me to work with the late Dr. William E. Paul for 17 years in the Laboratory of Immunology (LI) from 1998 until his passing in 2015. He was such a master in the immunology field. Under his outstanding guidance, my research ... ...

    Abstract It had been a great honor for me to work with the late Dr. William E. Paul for 17 years in the Laboratory of Immunology (LI) from 1998 until his passing in 2015. He was such a master in the immunology field. Under his outstanding guidance, my research has been focusing on transcriptional regulation of T helper (Th) cell differentiation, especially, on the role of a master transcription factor GATA3 during Th2 cell differentiation. Just as enormous scientific contributions of Dr. Paul (we all call him Bill) to the immunology community are far beyond his serving as the Chief of the LI, GATA3 also plays important roles in different lymphocytes at various developmental stages besides its critical functions in Th2 cells. In this special review dedicated to the memory of Bill, I will summarize the research that I have carried out in Bill's lab working on GATA3 in the context of related studies by other groups in the field of T cell differentiation and innate lymphoid cell (ILC) development. These include the essential role of GATA3 in regulating Th2/ILC2 differentiation/development and their functions, the critical role of GATA3 during the development of T cells and innate lymphoid cells, and dynamic and quantitative expression of GATA3 in controlling lymphocyte homeostasis and functions.
    MeSH term(s) Cell Differentiation ; Cytokines/immunology ; GATA3 Transcription Factor/immunology ; Gene Expression Regulation ; Humans ; Immunity, Innate ; Lymphocyte Activation ; Th2 Cells/immunology
    Chemical Substances Cytokines ; GATA3 Transcription Factor ; GATA3 protein, human
    Language English
    Publishing date 2018-05-02
    Publishing country Switzerland
    Document type Journal Article ; Personal Narrative ; Research Support, N.I.H., Intramural
    ZDB-ID 2606827-8
    ISSN 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2018.00960
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article: Water Uptake Tradeoffs of Dominant Shrub Species in the Coastal Wetlands of the Yellow River Delta, China.

    Zhu, Jinfang / Liu, Jingtao / Li, Junsheng / Zhao, Caiyun / Sun, Jingkuan

    Frontiers in plant science

    2022  Volume 13, Page(s) 935025

    Abstract: ... Tamarix ... ...

    Abstract Tamarix chinensis
    Language English
    Publishing date 2022-06-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2022.935025
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Differential regulation of lineage-determining transcription factor expression in innate lymphoid cell and adaptive T helper cell subsets.

    Fang, Difeng / Healy, Ayanna / Zhu, Jinfang

    Frontiers in immunology

    2023  Volume 13, Page(s) 1081153

    Abstract: CD4 T helper (Th) cell subsets, including Th1, Th2 and Th17 cells, and their innate counterparts innate lymphoid cell (ILC) subsets consisting of ILC1s, ILC2s and ILC3s, display similar effector cytokine-producing capabilities during pro-inflammatory ... ...

    Abstract CD4 T helper (Th) cell subsets, including Th1, Th2 and Th17 cells, and their innate counterparts innate lymphoid cell (ILC) subsets consisting of ILC1s, ILC2s and ILC3s, display similar effector cytokine-producing capabilities during pro-inflammatory immune responses. These lymphoid cell subsets utilize the same set of lineage-determining transcription factors (LDTFs) for their differentiation, development and functions. The distinct ontogeny and developmental niches between Th cells and ILCs indicate that they may adopt different external signals for the induction of LDTF during lineage commitment. Increasing evidence demonstrates that many conserved cis-regulatory elements at the gene loci of LDTFs are often preferentially utilized for the induction of LDTF expression during Th cell differentiation and ILC development at different stages. In this review, we discuss the functions of lineage-related cis-regulatory elements in inducing T-bet, GATA3 or RORγt expression based on the genetic evidence provided in recent publications. We also review and compare the upstream signals involved in LDTF induction in Th cells and ILCs both
    MeSH term(s) Transcription Factors/genetics ; Transcription Factors/metabolism ; Lymphocytes ; Immunity, Innate ; Gene Expression Regulation ; T-Lymphocytes, Helper-Inducer
    Chemical Substances Transcription Factors
    Language English
    Publishing date 2023-01-04
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, N.I.H., Intramural
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.1081153
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top