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  1. Book: Climate change, climate science and economics

    Van Kooten, Gerrit C.

    prospects for an alternative energy future

    2013  

    Author's details G. Cornelis van Kooten
    Language English
    Size XXIII, 466 S. : graph. Darst.
    Publisher Springer
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book
    Note (Preis inkl. MwSt.) 139,05 €
    HBZ-ID HT017356069
    ISBN 978-94-007-4987-0 ; 9789400749887 ; 94-007-4987-2 ; 9400749880
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    128/766 available for loan (reading room) Freihandmagazin (U1)

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  2. Book: Climate change economics

    Van Kooten, Gerrit C.

    why international accords fail

    2004  

    Author's details G. Cornelis van Kooten
    Keywords Climatic changes/Economic aspects ; Environmental policy/Economic aspects ; Environmental impact charges ; Environmental policy/International cooperation
    Subject code 363.73874
    Language English
    Size VIII, 167 S. : graph. Darst.
    Publisher Elgar
    Publishing place Cheltenham u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT014006430
    ISBN 1-84376-812-7 ; 978-1-84376-812-8
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    048/912 available for loan (reading room) Freihandmagazin (U1)

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  3. Article ; Online: Beyond Encapsulation: Exploring Macrophage-Fibroblast Cross Talk in Implant-Induced Fibrosis.

    Sudarsanam, Phani Krishna / Alsema, Els C / Beijer, Nick R M / Kooten, Theo van / Boer, Jan de

    Tissue engineering. Part B, Reviews

    2024  

    Abstract: The foreign body response (FBR) and organ fibrosis are complex biological processes involving the interaction between macrophages and fibroblasts. Understanding the molecular mechanisms underlying macrophage-fibroblast cross talk is crucial for ... ...

    Abstract The foreign body response (FBR) and organ fibrosis are complex biological processes involving the interaction between macrophages and fibroblasts. Understanding the molecular mechanisms underlying macrophage-fibroblast cross talk is crucial for developing strategies to mitigate implant encapsulation, a major cause of implant failure. This article reviews the current knowledge on the role of macrophages and fibroblasts in the FBR and organ fibrosis, highlighting the similarities between these processes. The FBR is characterized by the formation of a fibrotic tissue capsule around the implant, leading to functional impairment. Various factors, including material properties such as surface chemistry, stiffness, and topography, influence the degree of encapsulation. Cross talk between macrophages and fibroblasts plays a critical role in both the FBR and organ fibrosis. However, the precise molecular mechanisms remain poorly understood. Macrophages secrete a wide range of cytokines that modulate fibroblast behavior such as abundant collagen deposition and myofibroblast differentiation. However, the heterogeneity of macrophages and fibroblasts and their dynamic behavior in different tissue environments add complexity to this cross talk. Experimental evidence from
    Language English
    Publishing date 2024-03-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2420584-9
    ISSN 1937-3376 ; 1937-3368
    ISSN (online) 1937-3376
    ISSN 1937-3368
    DOI 10.1089/ten.TEB.2023.0300
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5500/B: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: An energetic approach to the evolution of growth curve plasticity

    Croll, Jasper C. / Van kooten, Tobias / de Roos, André M.

    Theoretical Ecology

    2024  Volume 17, Issue 1

    Abstract: Growth in individual body size amongst different species can to a greater or lesser extent depend on environmental factors such as resource availability. Individual growth curves can therefore be largely fixed or more plastic. Classic theory about ... ...

    Abstract Growth in individual body size amongst different species can to a greater or lesser extent depend on environmental factors such as resource availability. Individual growth curves can therefore be largely fixed or more plastic. Classic theory about phenotypic plasticity assumes that such plasticity has associated costs. In contrast, according to dynamic energy budget theory, maintaining a fixed growth rate in the face of variable resource availability would incur additional energetic costs. In this article, we explore the simultaneous evolution of the degree of plasticity in individual growth curves and the rate of non-plastic, environment-independent individual growth. We explore different relations between possible additional energetic costs and the degree of growth curve plasticity. To do so, we use adaptive dynamics to analyze a size-structured population model that is based on dynamic energy budget theory to account for the energetic trade-offs within an individual. We show that simultaneous evolution of the degree of growth curve plasticity and the rate of non-plastic individual growth will drive these traits to intermediate values at first. Afterwards, the degree of growth curve plasticity might evolve slowly towards extreme values depending on whether energetic costs increase or decrease with the degree of plasticity. In addition, the analysis shows that it is unlikely to encounter species in which individual growth is entirely fixed or entirely plastic, opposing general assumptions in dynamic energy budget theory.
    Keywords Life Science
    Subject code 339
    Language English
    Publishing country nl
    Document type Article ; Online
    ZDB-ID 2391025-2
    ISSN 1874-1746 ; 1874-1738
    ISSN (online) 1874-1746
    ISSN 1874-1738
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  5. Book: Conserving nature's diversity

    Van Kooten, Gerrit C.

    insights from biology, ethics and economics

    (Ashgate studies in environmental and natural resource economics)

    2000  

    Author's details ed. by G. Cornelis van Kooten
    Series title Ashgate studies in environmental and natural resource economics
    Keywords Biodiversität ; Naturschutz ; Ethik
    Subject Ethische Theorie ; Moral ; Philosophische Ethik ; Sittenlehre ; Moralphilosophie ; Biologische Vielfalt ; Vielfalt
    Language English
    Size XII, 206 S.
    Publisher Ashgate
    Publishing place Aldershot u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT012881706
    ISBN 0-7546-1090-X ; 978-0-7546-1090-8
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    008/2705 available for loan (reading room) Freihandmagazin (U1)

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  6. Book: Fuzzy measures for a fuzzy concept

    Van Kooten, Gerrit C. / Wohl, Jennifer / Ells, Arlene

    a new approach to nonmarket valuation

    (Discussion papers in agricultural economics ; No. 35)

    1996  

    Author's details by G. Cornelis van Kooten, Jennifer Wohl and Arlene Ells. Ed. by: Institute of Agriculture Policy and Market Research, Justus Liebig University Giessen. [University of Giessen]
    Series title Discussion papers in agricultural economics ; No. 35
    Agrarökonomische Diskussionsbeiträge
    Collection Agrarökonomische Diskussionsbeiträge
    Size 27 S. : graph. Darst.
    Publisher Inst. für Agrarpolitik und Marktforschung
    Publishing place Giessen
    Document type Book
    HBZ-ID HT010740748
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    994/1059 available for loan (reading room) Freihandmagazin (U1)

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  7. Book ; Online: Is commodity storage an option for enhancing food security in developing countries?

    Van Kooten, Gerrit C

    (Working paper ; 2018, 01)

    2018  

    Author's details G. Cornelis van Kooten
    Series title Working paper ; 2018, 01
    Language English
    Size 1 Online-Ressource (circa 21 Seiten), Illustrationen
    Document type Book ; Online
    Database ECONomics Information System

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    Inter-library loan at ZB MED

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  8. Book: The economics of nature

    Van Kooten, Gerrit C. / Bulte, Erwin H.

    managing biological assets

    2000  

    Author's details G. Cornelis van Kooten ; Erwin H. Bulte
    Keywords Naturschutz ; Wirtschaftstheorie ; Umweltökonomie ; Umweltschutz ; Wert
    Subject Soziale Werte ; Sozialer Wert ; Werte ; Ökologie ; Umweltvorsorge ; Green ecology ; Umweltökonomik ; Umweltschutz ; Ökologische Ökonomie ; Ökonomische Theorie ; Volkswirtschaftstheorie ; Sozialökonomie ; Sozialökonomik ; Sozioökonomie
    Language English
    Size XVIII, 512 S. : graph. Darst.
    Publisher Blackwell
    Publishing place Malden, Mass
    Publishing country United States
    Document type Book
    HBZ-ID HT012799722
    ISBN 0-631-21895-5 ; 0-631-21894-7 ; 978-0-631-21895-1 ; 978-0-631-21894-4
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    008/1158 available for loan (reading room) Freihandmagazin (U1)

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  9. Article ; Online: Conversion from calcineurin inhibitors to belatacept-based immunosuppressive therapy skews terminal proliferation of non-classical monocytes and lowers lymphocyte counts.

    Bredewold, O W / van Oeveren-Rietdijk, A M / Florijn, B / Rotmans, J I / de Fijter, J W / van Kooten, C / van Zonneveld, A J / de Boer, H C

    Transplant immunology

    2024  Volume 82, Page(s) 101976

    Abstract: Belatacept, a modified form of CTLA-Ig that blocks CD28-mediated co-stimulation of T cells, is an immune-suppressant that can be used as an alternative to calcineurin inhibitors (CNIs). In kidney transplant recipients, belatacept has been associated with ...

    Abstract Belatacept, a modified form of CTLA-Ig that blocks CD28-mediated co-stimulation of T cells, is an immune-suppressant that can be used as an alternative to calcineurin inhibitors (CNIs). In kidney transplant recipients, belatacept has been associated with improved renal function and reduced cardiovascular toxicity. Monocytes as well as T-lymphocytes play causal roles in the pathophysiology of atherosclerotic disease. We hypothesized that the beneficial impact of the use of belatacept over CNIs on cardiovascular risk could be partly explained by the impact of belatacept therapy on these circulating leukocytes. Hence, we phenotyped circulating leukocytes in transplanted patients with a stable renal function that were randomized between either continuation of CNI or conversion to belatacept in two international studies in which we participated. In 41 patients, we found that belatacept-treated patients consistently showed lower numbers of B-lymphocytes, T-lymphocytes as well as CD14-negative monocytes (CD14NM), especially in non-diabetic patients. Our observation that this decrease was associated to plasma concentrations of TNFα is consistent with a model where CD14NM-production of TNFα is diminished by belatacept-treatment, due to effects on the antigen-presenting cell compartment.
    MeSH term(s) Humans ; Abatacept/therapeutic use ; Calcineurin Inhibitors/therapeutic use ; Cell Proliferation ; Graft Rejection/drug therapy ; Graft Rejection/prevention & control ; Immunosuppression Therapy/methods ; Immunosuppressive Agents/therapeutic use ; Kidney Transplantation/adverse effects ; Monocytes ; Tumor Necrosis Factor-alpha
    Chemical Substances Abatacept (7D0YB67S97) ; Calcineurin Inhibitors ; Immunosuppressive Agents ; Tumor Necrosis Factor-alpha
    Language English
    Publishing date 2024-01-08
    Publishing country Netherlands
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 1160846-8
    ISSN 1878-5492 ; 0966-3274
    ISSN (online) 1878-5492
    ISSN 0966-3274
    DOI 10.1016/j.trim.2023.101976
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3784: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Book ; Online: Can carbon offset trading promote economic development in forest-dependent and first nations communities?

    Van Kooten, Gerrit C

    (Working paper ; 2018, 02)

    2018  

    Author's details G. Cornelis van Kooten
    Series title Working paper ; 2018, 02
    Language English
    Size 1 Online-Ressource (circa 24 Seiten), Illustrationen
    Document type Book ; Online
    Database ECONomics Information System

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