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Article: Änderung der StVZO: Blaue Kennleuchten an Einsatzfahrzeugen - neuer Sachstand

Noelle, J. / Schubert, R.

2022 Volume 45, Issue 6, Page(s) 10

Language	German
Document type	Article
ZDB-ID	632510-5
ISSN	0178-2525
Database	Current Contents Medicine

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Article: Patient Engagement in Provincial and Territorial Medical Association Decision-Making: A Rapid Scoping Review.

Brown, Ryan / Graham, Samantha / Girard, Jennifer / Moulaison, Noelle

Cureus

2024 Volume 16, Issue 2, Page(s) e54400

Abstract: In recent years health systems have engaged patient partners in decision-making. Provincial and Territorial Medical Associations (PTMAs) are the sole bargaining agents for physicians. PTMA negotiations with governments are often seen as insular. Adding ... ...

Abstract	In recent years health systems have engaged patient partners in decision-making. Provincial and Territorial Medical Associations (PTMAs) are the sole bargaining agents for physicians. PTMA negotiations with governments are often seen as insular. Adding the patient perspective could add tremendous value to negotiating committees, etc. as PTMAs look to advocate for person-centered care provided by their members. Using rapid scoping review methodology, PubMed was searched for studies reporting on the use of patient partners in PTMA decision-making. Title and abstract screening were conducted by a single reviewer with full-text review screened by two reviewers. The search yielded 231 titles with 10 moving to full-text review and ultimately no titles meeting inclusion criteria. This empty scoping review has identified a paucity of literature reporting on patient engagement in PTMA decision-making. Further research is required to determine the utility of introducing patient partners in this capacity.
Language	English
Publishing date	2024-02-18
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.54400
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: A response to a letter to the editor: Predictors for operative treatment in pediatric proximal third both-bone diaphyseal forearm fractures in children include age and translation, but not initial angulation.

Williams, Kevin / Whyte, Noelle / Carl, Jacob R / Marks, Jennifer / Segal, David / Little, Kevin J

Journal of children's orthopaedics

2023 Volume 17, Issue 6, Page(s) 628–629

Language	English
Publishing date	2023-11-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2279410-4
ISSN	1863-2548 ; 1863-2521
ISSN (online)	1863-2548
ISSN	1863-2521
DOI	10.1177/18632521231205603
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Improving pre-emptive access to the kidney transplant waiting list between 2017 and 2021: Assessment of a regional program in Aquitaine

Mathilde, Prezelin-Reydit / Karine, Moreau / Frederic, Jambon / Eric, Alezra / Grégoire, Robert / Jean-Christophe, Bernhard / Savva, Assatourian / Cécile, Degryse / Noëlle, Boulonne / Arlette, Communier / Brigitte, Bonpunt / Benjamin, Daviller / Olivier, Delorme / Xabina, Larre / Hannah, Kaminski / Karen, Leffondré / Pierre, Merville / Lionel, Couzi

Nephrologie & therapeutique

2024 Volume 20, Issue 1, Page(s) 1–10

Abstract: Introduction: Pre-emptive access to the kidney transplant (KT) waiting list remains limited in France, with only 3.9% of patients on pre-emptive KT and 5.6% of patients registered at the time of initiation of dialysis. A similar trend was observed in ... ...

Title translation	Amélioration de l’accès préemptif à la liste d’attente de transplantation rénale entre 2017 et 2021 : bilan d’un programme régional en Aquitaine
Abstract	Introduction: Pre-emptive access to the kidney transplant (KT) waiting list remains limited in France, with only 3.9% of patients on pre-emptive KT and 5.6% of patients registered at the time of initiation of dialysis. A similar trend was observed in Aquitaine. The aim of this study was to assess the impact of a regional program in terms of access to the waiting list for patients initiating a kidney replacement therapy (KRT). Methods: We included all patients assessed for registration on the list between 2017 and 2020, 2017 being the reference year and 2018 the beginning of the program. Using the CRISTAL and REIN registries, we assessed changes in the number of patients on the list at the time of initiation of dialysis or transplantation. Results: The number of new assessed candidates increased gradually each year from 255 in 2017 to 352 in 2020 (+38%). The number of patients on the list sharply increased in 2018 from 229 in 2017 to 319 in 2018 (+39.3%) and then remained stable. At the initiation of KRT, the proportion of patients registered on the waiting list increased gradually from 7.1% in 2017 to 18.2% in 2020. The proportion of pre-emptive KT remained stable between 2017 and 2021 (around 7%) with a decrease in 2020 (4.6%). Approximately 60% of patients had a contraindication to transplantation throughout the study. Conclusion: This study showed that a regional program aimed at providing better information to healthcare professionals and patients and encouraging rapid assessment of transplant candidates could increase the rate of pre-emptive registration on the KT waiting list for eligible patients over 4 years.
Language	French
Publishing date	2024-01-30
Publishing country	France
Document type	Journal Article
ZDB-ID	2229575-6
ISSN	1872-9177 ; 1769-7255
ISSN (online)	1872-9177
ISSN	1769-7255
DOI	10.1684/ndt.2024.64
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Intra-habitat structural complexity drives the distribution of fish trait groups on coral reefs

Noelle K. Helder / John H.R. Burns / Stephanie J. Green

Ecological Indicators, Vol 142, Iss , Pp 109266- (2022)

2022

Abstract: Three-dimensional (3D) habitat complexity is a primary driver of organism distribution and community structure across ecosystems. Identifying the specific metrics and spatial scales at which complexity is functionally important for communities is ... ...

Abstract	Three-dimensional (3D) habitat complexity is a primary driver of organism distribution and community structure across ecosystems. Identifying the specific metrics and spatial scales at which complexity is functionally important for communities is therefore a critical component in forecasting ecosystem function. Here we pair fish species traits with multiple metrics from habitat photogrammetry to evaluate the most important measures and scales of 3D complexity driving ecological functions within one of the most structurally diverse ecosystems on the planet: coral reefs. From May to July 2019, we collected high-resolution (1 cm) large- and small-scale intra-habitat (25 m2) structural complexity data across eight reefscapes (∼2500 m2) and conducted co-located fish functional group surveys in the Florida Keys, FL, USA. We used a hierarchical clustering analysis to group 80 observed fish species by four traits related to habitat use (social level, body size, crypsis, activity period) and feeding guild to generate mechanistic predictions about fish-habitat relationships. Evaluating relationships between the resulting trait-based functional groups (k = 9) and four metrics of intra-habitat complexity (large-scale vertical relief, and small-scale vector ruggedness [VRM], VRM deviation, and profile curvature) revealed that trait groups respond independently to the various measures and scales of reef complexity. While large-scale complexity (relief) is strongly related to the presence of solitary, cryptic, nocturnal carnivores, likely due to prey availability as well as day-time refuge opportunities, herbivore abundance is unaffected by increasing vertical relief, potentially due to predator avoidance. Instead, gregarious (i.e., schooling) herbivores increase with small-scale complexity measured by VRM and VRM deviation across reefscapes, while less gregarious herbivores only respond to small-scale complexity when these same measures occur in low-relief habitat, possibly due to a tradeoff between grazing resource ...
Keywords	Structure-from-motion photogrammetry ; Coral reefs ; Habitat structural complexity ; Fish ; Species traits ; Coral restoration ; Ecology ; QH540-549.5
Subject code	590
Language	English
Publishing date	2022-09-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Predictors for operative treatment in pediatric proximal third both-bone diaphyseal forearm fractures in children include age and translation, but not initial angulation.

Williams, Kevin / Whyte, Noelle / Carl, Jacob R / Marks, Jennifer / Segal, David / Little, Kevin J

Journal of children's orthopaedics

2023 Volume 17, Issue 2, Page(s) 156–163

Abstract: Introduction: Proximal third diaphyseal fractures of the radius and ulna represent an onerous fracture pattern due to difficulty maintaining acceptable alignment with nonoperative management. Our aim was to identify the factors that increase the odds ... ...

Abstract	Introduction: Proximal third diaphyseal fractures of the radius and ulna represent an onerous fracture pattern due to difficulty maintaining acceptable alignment with nonoperative management. Our aim was to identify the factors that increase the odds for a surgical treatment of these fractures. Recognizing these factors can raise awareness to patients who are more likely to require additional care and assist clinicians in counseling families, targeting treatment plans, and constructing follow-up protocols. We hypothesized that the age of the patient, the amount of initial fracture displacement, and the angulation of the fracture would predict the need for operative treatment. Methods: We retrospectively reviewed 276 proximal third diaphyseal forearm fractures at a single tertiary care institution. All patients underwent a nonoperative treatment trial, and if failed continued to surgery. Following a univariate analysis, we constructed a binary multivariate logistic regression model that included age, initial translation, and initial angulation to assess the association between the tested variables. Results: A regression model revealed that age (10 years and older, odds ratio: 8.2, 95% confidence interval: 3.9-17.24, p < 0.001) and radius translation of more than 100% (odds ratio: 7.06, 95% confidence interval: 2.69-18.52, p < 0.001) were associated with the need for surgical treatment. Initial fracture angulation lacked an association with a surgical treatment (odds ratio: 0.81 95% confidence interval: 0.38-1.74, p = 0.59). Conclusion: Age above 10 years and 100% initial translation of the radius fracture increased the odds for an ultimate decision to perform a surgery. Initial angulation, although often being the most remarkable radiographic feature, was not associated with a nonoperative treatment failure. We recommend an initial reduction attempt after counseling patients and their families that there is a high rate of conversion to operative treatment when the above features are met. Level of evidence: level III.
Language	English
Publishing date	2023-02-28
Publishing country	England
Document type	Journal Article
ZDB-ID	2279410-4
ISSN	1863-2548 ; 1863-2521
ISSN (online)	1863-2548
ISSN	1863-2521
DOI	10.1177/18632521231156941
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Survival of the Hmong population diagnosed with colon and rectal cancers in the United States.

Walker, Margaret R / Lor, Kha / Lor, Kajua B / Vidri, Roberto J / Hampton, John M / Maldonado, Cinthya / Schiefelbein, Andrea M / LoConte, Noelle K

Cancer medicine

2024 Volume 13, Issue 5, Page(s) e7087

Abstract: Background: The Hmong population constitutes an independent ethnic group historically dispersed throughout Southeast Asia; fallout from the Vietnam War led to their forced migration to the United States as refugees. This study seeks to investigate ... ...

Abstract	Background: The Hmong population constitutes an independent ethnic group historically dispersed throughout Southeast Asia; fallout from the Vietnam War led to their forced migration to the United States as refugees. This study seeks to investigate characteristics of the Hmong population diagnosed with in colorectal cancer (CRC) as well as survival within this population. Methods: Cases of colon and rectal adenocarcinoma diagnosed between 2004 and 2017 were identified from the National Cancer Database (NCDB). Summary statistics of demographic, clinical, socioeconomic, and treatment variables were generated with emphasis on age and stage at the time of diagnosis. Cox-proportional hazard models were constructed for survival analysis. Results: Of 881,243 total CRC cases within the NCDB, 120 were classified as Hmong. The average age of Hmong individuals at diagnosis was 58.9 years compared 68.7 years for Non-Hispanic White (NHW) individuals (p < 0.01). The distribution of analytic stage differed between the Hmong population and the reference NHW population, with 61.8% of Hmong individuals compared to 45.8% of NHW individuals with known stage being diagnosed at stage III or IV CRC compared to 0, I, or II (p = 0.001). However, there was no difference in OS when adjusting for potential confounders (HR 1.00 [0.77-1.33]; p = 0.998). Conclusions: Hmong individuals are nearly a decade younger at the time of diagnosis of CRC compared to the NHW individuals. However, these data do not suggest an association between Hmong ethnicity and overall survival, when compared to the NHW population.
MeSH term(s)	United States/epidemiology ; Humans ; Middle Aged ; Rectal Neoplasms/diagnosis ; Rectal Neoplasms/epidemiology ; Ethnicity ; Databases, Factual ; Colon ; White
Language	English
Publishing date	2024-03-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	2659751-2
ISSN	2045-7634 ; 2045-7634
ISSN (online)	2045-7634
ISSN	2045-7634
DOI	10.1002/cam4.7087
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Monochrome Multiplex Quantitative PCR Telomere Length Measurement.

Martin, Noelle A / McLester-Davis, Lauren W Y / Roy, Trevor R / Magruder, Madeline G / Hastings, Waylon J / Drury, Stacy S

Journal of visualized experiments : JoVE

2024 , Issue 205

Abstract: Telomeres are ribonucleoprotein structures at the end of all eukaryotic chromosomes that protect DNA from damage and preserve chromosome stability. Telomere length (TL) has been associated with various exposures, biological processes, and health outcomes. ...

Abstract	Telomeres are ribonucleoprotein structures at the end of all eukaryotic chromosomes that protect DNA from damage and preserve chromosome stability. Telomere length (TL) has been associated with various exposures, biological processes, and health outcomes. This article describes the monochrome multiplex quantitative polymerase chain reaction (MMqPCR) assay protocol routinely conducted in our laboratory for measuring relative mean TL from human DNA. There are several different PCR-based TL measurement methods, but the specific protocol for the MMqPCR method presented in this publication is repeatable, efficient, cost-effective, and suitable for population-based studies. This detailed protocol outlines all information necessary for investigators to establish this assay in their laboratory. In addition, this protocol provides specific steps to increase the reproducibility of TL measurement by this assay, defined by the intraclass correlation coefficient (ICC) across repeated measurements of the same sample. The ICC is a critical factor in evaluating expected power for a specific study population; as such, reporting cohort-specific ICCs for any TL assay is a necessary step to enhance the overall rigor of population-based studies of TL. Example results utilizing DNA samples extracted from peripheral blood mononuclear cells demonstrate the feasibility of generating highly repeatable TL data using this MMqPCR protocol.
MeSH term(s)	Humans ; Reproducibility of Results ; Leukocytes, Mononuclear ; DNA ; Telomere/genetics ; Multiplex Polymerase Chain Reaction
Chemical Substances	DNA (9007-49-2)
Language	English
Publishing date	2024-03-22
Publishing country	United States
Document type	Journal Article ; Video-Audio Media
ZDB-ID	2259946-0
ISSN	1940-087X ; 1940-087X
ISSN (online)	1940-087X
ISSN	1940-087X
DOI	10.3791/66545
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Article ; Online: Segmentation of Change in Surface Geometry Analysis for Cultural Heritage Applications.

Saha, Sunita / Martusewicz, Jacek / Streeton, Noëlle L W / Sitnik, Robert

Sensors (Basel, Switzerland)

2021 Volume 21, Issue 14

Abstract: This work proposes a change-based segmentation method for applications to cultural heritage (CH) imaging to perform monitoring and assess changes at each surface point. It can be used as a support or component of the 3D sensors to analyze surface ... ...

Abstract	This work proposes a change-based segmentation method for applications to cultural heritage (CH) imaging to perform monitoring and assess changes at each surface point. It can be used as a support or component of the 3D sensors to analyze surface geometry changes. In this research, we proposed a new method to identify surface changes employing segmentation based on 3D geometrical data acquired at different time intervals. The geometrical comparison was performed by calculating point-to-point Euclidean distances for each pair of surface points between the target and source geometry models. Four other methods for local distance measurement were proposed and tested. In the segmentation method, we analyze the local histograms of the distances between the measuring points of the source and target models. Then the parameters of these histograms are determined, and predefined classes are assigned to target surface points. The proposed methodology was evaluated by considering two different case studies of restoration issues on CH surfaces and monitoring them over time. The results were presented with a colormap visualization for each category of the detected change in the analysis. The proposed segmentation method will help in the field of conservation and restoration for the documentation and quantification of geometrical surface change information. This analysis can help in decision-making for the assessment of damage and potential prevention of further damage, and the interpretation of measurement results.
MeSH term(s)	Algorithms ; Imaging, Three-Dimensional
Language	English
Publishing date	2021-07-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s21144899
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Article ; Online: Extraction and Matrix Cleanup Method for Analyzing Novel Per- and Polyfluoroalkyl Ether Acids and Other Per- and Polyfluoroalkyl Substances in Fruits and Vegetables.

Meng, Pingping / DeStefano, Noelle J / Knappe, Detlef R U

Journal of agricultural and food chemistry

2022 Volume 70, Issue 16, Page(s) 4792–4804

Abstract: Per- and polyfluoroalkyl ether acids (PFEAs) are a subclass of per- and polyfluoroalkyl substances (PFAS) that are detected with increasing frequency in environmental matrices. Diet can be an important route of PFEA exposure, but the presence of PFEAs in ...

Abstract	Per- and polyfluoroalkyl ether acids (PFEAs) are a subclass of per- and polyfluoroalkyl substances (PFAS) that are detected with increasing frequency in environmental matrices. Diet can be an important route of PFEA exposure, but the presence of PFEAs in food is poorly understood. Extraction methods for food samples exist for traditionally studied PFAS, but their suitability for PFEAs and other novel PFAS remains unknown. In this study, an extraction and matrix cleanup method was developed to quantify 45 PFAS, including 13 PFEAs, 3 perfluoroalkane sulfonamides, and 6 fluorotelomer carboxylic acids in 10 types of fruits and vegetables. Homogenized samples were extracted with basic methanol, and resulting extracts were diluted with water and cleaned up using solid-phase extraction with weak anion-exchange cartridges. The method was validated by performing spike-recovery experiments at spike levels of 1 ng/g in all 10 matrices and 0.1 ng/g in 2 matrices. For PFAS without a corresponding isotopically labeled internal standard (IS), adopting an IS with a similar chromatographic retention time generated the most accurate recoveries. Dependent upon the matrix, recoveries of 38-44 PFAS (including 10-13 PFEAs) fell within 50-150% for samples spiked at 1 ng/g. Recoveries of 40 and 38 PFAS in blueberries and corn, respectively, fell within 50-150% for samples spiked at 0.1 ng/g. Method quantification limits (MQLs) of PFAS in pure solvents were determined as the lowest calibration level with an accuracy between 70 and 130%. To compensate for matrix effects, a matrix factor was applied on the basis of the analyte response in different matrices relative to the pure solvent. The MQLs of 45 PFAS (including 13 PFEAs) in 10 matrices ranged from 0.025 to 0.25 ng/g. Overall, this method is capable of sensitively quantifying 45 PFAS in many fruits and vegetables.
MeSH term(s)	Ether ; Ethers ; Fluorocarbons/analysis ; Fruit/chemistry ; Vegetables
Chemical Substances	Ethers ; Fluorocarbons ; Ether (0F5N573A2Y)
Language	English
Publishing date	2022-02-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	241619-0
ISSN	1520-5118 ; 0021-8561
ISSN (online)	1520-5118
ISSN	0021-8561
DOI	10.1021/acs.jafc.1c07665
Database	MEDical Literature Analysis and Retrieval System OnLINE

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