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  1. Article ; Online: Educator's blueprint: A guide for clinician-educators to achieve promotion in emergency medicine.

    Gore, Katarzyna / Dyne, Pamela / Fitch, Michael T / Mattu, Amal / Pillow, M Tyson / Gottlieb, Michael

    AEM education and training

    2023  Volume 7, Issue 3, Page(s) e10883

    Abstract: Promotion and tenure (P&T) can be a complex process, which many junior faculty in academic ... application portfolio. This resource can inform faculty and faculty developers when planning for P&T. ...

    Abstract Promotion and tenure (P&T) can be a complex process, which many junior faculty in academic emergency medicine may struggle navigating. This paper presents perspectives and key considerations to guide faculty through the promotions process. We explore tips through three key phases: plotting the course for a successful academic career, collecting data to support academic advancement, and packaging materials into a compelling application portfolio. This resource can inform faculty and faculty developers when planning for P&T.
    Language English
    Publishing date 2023-05-29
    Publishing country United States
    Document type Journal Article
    ISSN 2472-5390
    ISSN (online) 2472-5390
    DOI 10.1002/aet2.10883
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Polygenic Scores and Preclinical Cardiovascular Disease in Individuals With HIV: Insights From the REPRIEVE Trial.

    Zou, Roger S / Ruan, Yunfeng / Truong, Buu / Bhattacharya, Romit / Lu, Michael T / Karády, Júlia / Bernardo, Rachel / Finneran, Phoebe / Hornsby, Whitney / Fitch, Kathleen V / Ribaudo, Heather J / Zanni, Markella V / Douglas, Pamela S / Grinspoon, Steven K / Patel, Aniruddh P / Natarajan, Pradeep

    Journal of the American Heart Association

    2024  Volume 13, Issue 7, Page(s) e033413

    Abstract: Background: Coronary artery disease (CAD) is a leading cause of death among the 38.4 million people with HIV globally. The extent to which cardiovascular polygenic risk scores (PRSs) derived in non-HIV populations generalize to people with HIV is not ... ...

    Abstract Background: Coronary artery disease (CAD) is a leading cause of death among the 38.4 million people with HIV globally. The extent to which cardiovascular polygenic risk scores (PRSs) derived in non-HIV populations generalize to people with HIV is not well understood.
    Methods and results: PRSs for CAD (GPS
    Conclusions: Among people with HIV treated with antiretroviral therapy without documented atherosclerotic cardiovascular disease and at low-to-moderate calculated risk in REPRIEVE, an externally developed CAD PRS was predictive of subclinical atherosclerosis. PRS for low-density lipoprotein cholesterol was also associated with subclinical atherosclerosis, supporting a role for low-density lipoprotein cholesterol in HIV-associated CAD.
    Registration: URL: https://www.reprievetrial.org; Unique identifier: NCT02344290.
    MeSH term(s) Humans ; Female ; Middle Aged ; Male ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/genetics ; Cardiovascular Diseases/complications ; Coronary Artery Disease/complications ; Plaque, Atherosclerotic/complications ; Atherosclerosis/complications ; Risk Factors ; HIV Infections/complications ; HIV Infections/diagnosis ; HIV Infections/drug therapy ; Computed Tomography Angiography/methods ; Cholesterol, LDL ; Coronary Angiography
    Chemical Substances Cholesterol, LDL
    Language English
    Publishing date 2024-03-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.123.033413
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Cytomegalovirus IgG is Associated With Physical Function But Not Muscle Density in People With HIV.

    Abidi, Maheen Z / Umbleja, Triin / Overton, Edgar T / Burdo, Tricia / Flynn, Jacqueline M / Lu, Michael T / Taron, Jana / Schnittman, Samuel R / Fitch, Kathleen V / Zanni, Markella V / Fichtenbaum, Carl J / Malvestutto, Carlos / Aberg, Judith A / Fulda, Evelynne S / Eckard, Allison Ross / Manne-Goehler, Jennifer / Tuan, Jessica J / Ribaudo, Heather J / Douglas, Pamela S /
    Grinspoon, Steven K / Brown, Todd T / Erlandson, Kristine M

    Journal of acquired immune deficiency syndromes (1999)

    2024  Volume 95, Issue 5, Page(s) 470–478

    Abstract: Background: Cytomegalovirus (CMV) seropositivity is associated with poor outcomes, including physical function impairment, in people without HIV. We examined associations between CMV IgG titer and physical function in virologically suppressed people ... ...

    Abstract Background: Cytomegalovirus (CMV) seropositivity is associated with poor outcomes, including physical function impairment, in people without HIV. We examined associations between CMV IgG titer and physical function in virologically suppressed people with HIV (PWH).
    Methods: REPRIEVE is a double-blind randomized trial evaluating pitavastatin for primary prevention of atherosclerotic cardiovascular disease in PWH. This analysis focused on participants enrolled in a substudy with additional biomarker testing, imaging [coronary CT angiography], and physical function measures at entry. CMV IgG was measured using quantitative enzyme immunoassay, physical function by Short Physical Performance Battery, and muscle density and area by CT. Associations between CMV IgG (risk factor) and outcomes were evaluated using the partial Spearman correlation and linear and log-binomial regression.
    Results: Among 717 participants, 82% male, the median CMV IgG was 2716 (Q1, Q3: 807, 6672) IU/mL, all above the limit of quantification. Among 631 participants with imaging, there was no association between CMV IgG and CT-based muscle density or area, controlling for age (r = -0.03 and r = -0.01, respectively; P ≥ 0.38). Among 161 participants with physical function data, higher CMV IgG was associated with poorer overall modified Short Physical Performance Battery score ( P = 0.02), adjusted for age, nadir CD4, and high-sensitivity C-reactive protein.
    Conclusions: Higher CMV IgG titer was associated with poorer physical function, not explained by previous immune compromise, inflammation, or muscle density or area. Further mechanistic studies are needed to understand this association and whether CMV-specific therapy can affect physical function in PWH.
    MeSH term(s) Humans ; Male ; Female ; Cytomegalovirus ; Cytomegalovirus Infections/complications ; HIV Infections/complications ; HIV Infections/drug therapy ; Muscles ; Immunoglobulin G ; Antibodies, Viral
    Chemical Substances Immunoglobulin G ; Antibodies, Viral
    Language English
    Publishing date 2024-01-05
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 645053-2
    ISSN 1944-7884 ; 1077-9450 ; 0897-5965 ; 0894-9255 ; 1525-4135
    ISSN (online) 1944-7884 ; 1077-9450
    ISSN 0897-5965 ; 0894-9255 ; 1525-4135
    DOI 10.1097/QAI.0000000000003377
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The Coexistence of Carpal Tunnel Syndrome in Workers With Trigger Digit.

    Fitch, Michael S / Thiese, Matthew S / Wood, Eric M / Kapellusch, Jay M / Hegmann, Kurt T

    Hand (New York, N.Y.)

    2020  Volume 16, Issue 6, Page(s) 753–758

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Carpal Tunnel Syndrome/epidemiology ; Carpal Tunnel Syndrome/etiology ; Cross-Sectional Studies ; Humans ; Logistic Models ; Prevalence ; Trigger Finger Disorder/epidemiology ; Trigger Finger Disorder/etiology
    Language English
    Publishing date 2020-01-22
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 2277325-3
    ISSN 1558-9455 ; 1558-9447
    ISSN (online) 1558-9455
    ISSN 1558-9447
    DOI 10.1177/1558944719893048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Associations of Muscle Density and Area With Coronary Artery Plaque and Physical Function.

    Erlandson, Kristine M / Umbleja, Triin / Lu, Michael T / Taron, Jana / Ribaudo, Heather J / Overton, Edgar T / Presti, Rachel M / Haas, David W / Sax, Paul E / Yin, Michael T / Zhai, Bingxue Kris / Louis, Rochelle / Upadhyay, Namrata / Eslami, Parastou / Douglas, Pamela S / Zanni, Markella V / Fitch, Kathleen V / Fulda, Evelynne S / Fichtenbaum, Carl J /
    Malvestutto, Carlos D / Grinspoon, Steven K / Brown, Todd T

    Journal of acquired immune deficiency syndromes (1999)

    2023  Volume 94, Issue 2, Page(s) 174–184

    Abstract: Objective: Skeletal muscle quality and mass are important for maintaining physical function during advancing age. We leveraged baseline data from Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE) to evaluate whether paraspinal muscle density ...

    Abstract Objective: Skeletal muscle quality and mass are important for maintaining physical function during advancing age. We leveraged baseline data from Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE) to evaluate whether paraspinal muscle density and muscle area are associated with cardiac or physical function outcomes in people with HIV (PWH).
    Methods: REPRIEVE is a double-blind randomized trial evaluating the effect of pitavastatin for primary prevention of major adverse cardiovascular events in PWH. This cross-sectional analysis focuses on participants who underwent coronary computed tomography at baseline. Lower thoracic paraspinal muscle density (Hounsfield units [HU]) and area (cm 2 ) were assessed on noncontrast computed tomography.
    Results: Of 805 PWH, 708 had paraspinal muscle measurements. The median age was 51 years and 17% were natal female patients. The median muscle density was 41 HU (male) and 30 HU (female); area 13.2 cm 2 /m (male) and 9.9 cm 2 /m (female). In adjusted analyses, greater density (less fat) was associated with a lower prevalence of any coronary artery plaque, coronary artery calcium score >0, and high plaque burden ( P = 0.06); area was not associated with plaque measures. Among 139 patients with physical function measures, greater area (but not density) was associated with better performance on a short physical performance battery and grip strength.
    Conclusions: Among PWH, greater paraspinal muscle density was associated with a lower prevalence of coronary artery disease while greater area was associated with better physical performance. Whether changes in density or area are associated with changes in CAD or physical performance will be evaluated through longitudinal analyses in REPRIEVE.
    MeSH term(s) Humans ; Male ; Female ; Middle Aged ; Coronary Angiography/methods ; Coronary Vessels/diagnostic imaging ; Cross-Sectional Studies ; Risk Factors ; HIV Infections/complications ; Computed Tomography Angiography ; Coronary Artery Disease/complications ; Plaque, Atherosclerotic/diagnostic imaging ; Plaque, Atherosclerotic/complications ; Muscle, Skeletal
    Language English
    Publishing date 2023-06-28
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 645053-2
    ISSN 1944-7884 ; 1077-9450 ; 0897-5965 ; 0894-9255 ; 1525-4135
    ISSN (online) 1944-7884 ; 1077-9450
    ISSN 0897-5965 ; 0894-9255 ; 1525-4135
    DOI 10.1097/QAI.0000000000003244
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Pediatric Needle Cricothyrotomy: A Case for Simulation in Prehospital Medicine.

    Stopyra, Jason P / Wright, Jamie L / Fitch, Michael T / Mitchell, Michael S

    MedEdPORTAL : the journal of teaching and learning resources

    2017  Volume 13, Page(s) 10589

    Abstract: Introduction: A patient that cannot be oxygenated or ventilated requires immediate and effective assessment, treatment, and transportation. Pediatric needle cricothyrotomy is used infrequently, therefore providers have a tendency to lose proficiency. ... ...

    Abstract Introduction: A patient that cannot be oxygenated or ventilated requires immediate and effective assessment, treatment, and transportation. Pediatric needle cricothyrotomy is used infrequently, therefore providers have a tendency to lose proficiency. Simulation training and evaluation are valuable tools to improve provider experience and skill.
    Methods: A case was designed involving a 3-year-old male with a peanut allergy that presents with rash, swelling, and severe respiratory distress. The patient's respiratory distress and swelling worsens despite treatment with epinephrine and other allergic reaction medications. The patient then becomes unresponsive and impossible to oxygenate or ventilate. The primary objective of this case is airway management with needle cricothyrotomy in the pediatric population. A secondary objective is appropriate postprocedure management including appropriate ventilation rates and emergency medical transportation methods.
    Results: This case was initially presented to 45 paramedics. Provider comfort with managing airway emergencies in young children improved from 47% to 89%. Confidence in performing pediatric needle cricothyrotomy improved from 16% to 87%. All providers felt the exercise was valuable and 98% felt the simulation provided appropriate realism.
    Discussion: This scenario provides an outstanding opportunity for paramedic evaluation and training in pediatric needle cricothyrotomy and significantly improved the comfort level of providers' management of a failed pediatric airway. As we reflected on the use of this module, it was apparent that this was a very beneficial opportunity to spend one-on-one time between participants and their medical director. The training staff also benefited from the repeated emphasis of good assessment and treatment of a complex patient scenario.
    Language English
    Publishing date 2017-06-02
    Publishing country United States
    Document type Journal Article
    ISSN 2374-8265
    ISSN (online) 2374-8265
    DOI 10.15766/mep_2374-8265.10589
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A Retrospective Observational Analysis of Overall Survival with Sipuleucel-T in Medicare Beneficiaries Treated for Advanced Prostate Cancer.

    McKay, Rana R / Hafron, Jason M / Ferro, Christine / Wilfehrt, Helen M / Fitch, Kate / Flanders, Scott C / Fabrizio, Michael D / Schweizer, Michael T

    Advances in therapy

    2020  Volume 37, Issue 12, Page(s) 4910–4929

    Abstract: Introduction: Since sipuleucel-T approval in 2010, the treatment landscape for metastatic ... observation period. We compared: first-line sipuleucel-T vs. first-line ASPIs and any-line sipuleucel-T vs ... any-line ASPIs (without sipuleucel-T). We used a multivariable regression model to help control ...

    Abstract Introduction: Since sipuleucel-T approval in 2010, the treatment landscape for metastatic castration-resistant prostate cancer (mCRPC) now includes the androgen-receptor signaling pathway inhibitors (ASPIs) abiraterone acetate or enzalutamide. In 2013 and 2014, these oral agents were approved for use in men with metastatic prostate cancer who had minimal to no symptoms. We compared overall survival (OS) in men who received their first mCRPC treatment using the Medicare Fee-for-Service 100% administrative claims research dataset with patient-level linkage to the National Death Index.
    Methods: This retrospective cohort analysis (January 2013 to December 2017) included men who were chemo-naïve at treatment start in 2014 and who had continuous Medicare Parts A, B, and D eligibility during the 3-year observation period. We compared: first-line sipuleucel-T vs. first-line ASPIs and any-line sipuleucel-T vs. any-line ASPIs (without sipuleucel-T). We used a multivariable regression model to help control for potentially confounding factors while assessing survival outcomes.
    Results: The model included 6044 eligible men (average age 75-78 years) with similar disease severity; > 80% were white. Median OS, presented as sipuleucel-T vs. ASPI, was 35.2 vs. 20.7 months (n, 906 vs. 5092; any-line cohort) and 34.9 vs. 21.0 months (n, 647 vs. 4810; first-line cohort). Model outcomes indicated sipuleucel-T was associated with significantly prolonged OS compared with ASPIs: adjusted hazard ratio, 0.59 (95% CI 0.527-0.651) and 0.56 (0.494-0.627) for the any-line and first-line cohorts, respectively.
    Conclusion: This analysis suggests use of sipuleucel-T at any time was associated with improved OS compared with ASPI use alone. Of note, these analyses are intended as descriptive rather than definitive as this dataset contains limited data on key clinical factors. While selection bias is a risk in secondary claims data, this research provides important insight into real-world treatment outcomes.
    MeSH term(s) Abiraterone Acetate/therapeutic use ; Aged ; Aged, 80 and over ; Antineoplastic Agents, Immunological/therapeutic use ; Cohort Studies ; Disease-Free Survival ; Humans ; Male ; Medicare ; Phenylthiohydantoin/analogs & derivatives ; Phenylthiohydantoin/therapeutic use ; Prostatic Neoplasms, Castration-Resistant/drug therapy ; Prostatic Neoplasms, Castration-Resistant/pathology ; Retrospective Studies ; Tissue Extracts/therapeutic use ; Treatment Outcome ; United States
    Chemical Substances Antineoplastic Agents, Immunological ; Tissue Extracts ; Phenylthiohydantoin (2010-15-3) ; sipuleucel-T (8Q622VDR18) ; enzalutamide (93T0T9GKNU) ; Abiraterone Acetate (EM5OCB9YJ6)
    Language English
    Publishing date 2020-10-07
    Publishing country United States
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 632651-1
    ISSN 1865-8652 ; 0741-238X
    ISSN (online) 1865-8652
    ISSN 0741-238X
    DOI 10.1007/s12325-020-01509-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Risk factors for clonal hematopoiesis of indeterminate potential in people with HIV: a report from the REPRIEVE trial.

    Bhattacharya, Romit / Uddin, Md Mesbah / Patel, Aniruddh P / Niroula, Abhishek / Finneran, Phoebe / Bernardo, Rachel / Fitch, Kathleen V / Lu, Michael T / Bloomfield, Gerald S / Malvestutto, Carlos / Aberg, Judy A / Fichtenbaum, Carl J / Hornsby, Whitney / Ribaudo, Heather J / Libby, Peter / Ebert, Benjamin L / Zanni, Markella V / Douglas, Pamela S / Grinspoon, Steven K /
    Natarajan, Pradeep

    Blood advances

    2024  Volume 8, Issue 4, Page(s) 959–967

    Abstract: Abstract: Clonal hematopoiesis of indeterminate potential (CHIP), the clonal expansion of myeloid cells with leukemogenic mutations, results in increased coronary artery disease (CAD) risk. CHIP is more prevalent among people with HIV (PWH), but the ... ...

    Abstract Abstract: Clonal hematopoiesis of indeterminate potential (CHIP), the clonal expansion of myeloid cells with leukemogenic mutations, results in increased coronary artery disease (CAD) risk. CHIP is more prevalent among people with HIV (PWH), but the risk factors are unknown. CHIP was identified among PWH in REPRIEVE (Randomized Trial to Prevent Vascular Events in HIV) using whole-exome sequencing. Logistic regression was used to associate sociodemographic factors and HIV-specific factors with CHIP adjusting for age, sex, and smoking status. In the studied global cohort of 4486 PWH, mean age was 49.9 (standard deviation [SD], 6.4) years; 1650 (36.8%) were female; and 3418 (76.2%) were non-White. CHIP was identified in 223 of 4486 (4.97%) and in 38 of 373 (10.2%) among those aged ≥60 years. Age (odds ratio [OR], 1.07; 95% confidence interval [CI], 1.05-1.09; P < .0001) and smoking (OR, 1.37; 95% CI, 1.14-1.66; P < .001) associated with increased odds of CHIP. Globally, participants outside of North America had lower odds of CHIP including sub-Saharan Africa (OR, 0.57; 95% CI, 0.4-0.81; P = .0019), South Asia (OR, 0.45; 95% CI, 0.23-0.80; P = .01), and Latin America/Caribbean (OR, 0.56; 95% CI, 0.34-0.87; P = .014). Hispanic/Latino ethnicity (OR, 0.38; 95% CI, 0.23-0.54; P = .002) associated with significantly lower odds of CHIP. Among HIV-specific factors, CD4 nadir <50 cells/mm3 associated with a 1.9-fold (95%CI, 1.21-3.05; P = .006) increased odds of CHIP, with the effect being significantly stronger among individuals with short duration of antiretroviral therapy (ART; OR, 4.15; 95% CI, 1.51-11.1; P = .005) (Pinteraction= .0492). Among PWH at low-to-moderate CAD risk on stable ART, smoking, CD4 nadir, North American origin, and non-Hispanic ethnicity associated with increased odds of CHIP. This trial was registered at www.ClinicalTrials.gov as NCT02344290.
    MeSH term(s) Humans ; Female ; Middle Aged ; Male ; Clonal Hematopoiesis ; Risk Factors ; HIV Infections/drug therapy ; HIV Infections/complications ; North America ; Ethnicity
    Language English
    Publishing date 2024-01-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2915908-8
    ISSN 2473-9537 ; 2473-9529
    ISSN (online) 2473-9537
    ISSN 2473-9529
    DOI 10.1182/bloodadvances.2023011324
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Recurrent spontaneous globe subluxation: a case report and review of manual reduction techniques.

    Kelly, Elizabeth W / Fitch, Michael T

    The Journal of emergency medicine

    2013  Volume 44, Issue 1, Page(s) e17–20

    Abstract: Background: Spontaneous globe subluxation is an uncommon problem that develops acutely and can present with significant patient distress from ocular pain and vision loss.: Objectives: To present an unusual case of recurrent spontaneous globe ... ...

    Abstract Background: Spontaneous globe subluxation is an uncommon problem that develops acutely and can present with significant patient distress from ocular pain and vision loss.
    Objectives: To present an unusual case of recurrent spontaneous globe subluxation and describe several methods emergency physicians can use to reduce a subluxation.
    Case report: We describe a patient with recurrent spontaneous globe subluxation who presented to the Emergency Department with acute ocular pain and vision loss. The subluxation was emergently reduced, resolving the pain and restoring normal vision. Various manual reduction techniques are discussed.
    Conclusion: There are a number of manual reduction techniques used for treating spontaneous globe subluxation.
    MeSH term(s) Exophthalmos/therapy ; Humans ; Male ; Middle Aged ; Orbital Diseases/therapy ; Recurrence ; Treatment Outcome
    Language English
    Publishing date 2013-01
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 605559-x
    ISSN 0736-4679
    ISSN 0736-4679
    DOI 10.1016/j.jemermed.2011.06.129
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Using high-fidelity emergency simulation with large groups of preclinical medical students in a basic science course.

    Fitch, Michael T

    Medical teacher

    2007  Volume 29, Issue 2-3, Page(s) 261–263

    Abstract: Background: High-fidelity patient simulation is often used to teach clinical patient management and decision-making with small groups. This pilot project determined feasibility for large-group educational presentations using simulation for preclinical ... ...

    Abstract Background: High-fidelity patient simulation is often used to teach clinical patient management and decision-making with small groups. This pilot project determined feasibility for large-group educational presentations using simulation for preclinical basic science courses.
    Methods: We developed an emergency patient simulation encounter illustrating basic neuroscience concepts. Physician actors interacted with a high-fidelity simulated patient mannequin in a lecture hall. First and second year medical students were active participants in the 90 minute live event in large groups. Digital video was recorded and written feedback was obtained from participants.
    Results: The simulation was presented four times to a total of 202 students. Video review demonstrated extensive interaction within the large groups. Case management discussions included basic science topics, autonomic pathways, and neuropharmacology. Student feedback revealed 98% rated the correlation to basic science concepts as very good or outstanding, and 99% rated the same for overall presentation.
    Conclusions: Live large-group simulation presentations are feasible in a non-traditional location, correlate with basic science in the preclinical medical curriculum, and are well-received by students.
    MeSH term(s) Education, Medical, Undergraduate/methods ; Emergencies ; Feasibility Studies ; Humans ; Manikins ; Neurosciences/education ; Pilot Projects ; Role Playing ; Students, Medical
    Language English
    Publishing date 2007-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 424426-6
    ISSN 1466-187X ; 0142-159X
    ISSN (online) 1466-187X
    ISSN 0142-159X
    DOI 10.1080/01421590701297334
    Database MEDical Literature Analysis and Retrieval System OnLINE

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