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Article ; Online: Chest Radiography in COVID-19: No Role in Asymptomatic and Oligosymptomatic Disease.

Schaefer-Prokop, Cornelia / Prokop, Mathias

2020 Volume 298, Issue 3, Page(s) E156–E157

MeSH term(s)	COVID-19 ; Humans ; Lung ; Radiography ; SARS-CoV-2 ; Singapore
Language	English
Publishing date	2020-12-08
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	80324-8
ISSN	1527-1315 ; 0033-8419
ISSN (online)	1527-1315
ISSN	0033-8419
DOI	10.1148/radiol.2020204038
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Human-AI Symbiosis: A Path Forward to Improve Chest Radiography and the Role of Radiologists in Patient Care.

Gefter, Warren B / Prokop, Mathias / Seo, Joon Beom / Raoof, Suhail / Langlotz, Curtis P / Hatabu, Hiroto

Radiology

2024 Volume 310, Issue 1, Page(s) e232778

MeSH term(s)	Humans ; Symbiosis ; Patient Care ; Radiography ; Radiologists
Language	English
Publishing date	2024-01-12
Publishing country	United States
Document type	Editorial
ZDB-ID	80324-8
ISSN	1527-1315 ; 0033-8419
ISSN (online)	1527-1315
ISSN	0033-8419
DOI	10.1148/radiol.232778
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Article: Review of strategies to reduce the contamination of the water environment by gadolinium-based contrast agents.

Dekker, Helena M / Stroomberg, Gerard J / Van der Molen, Aart J / Prokop, Mathias

Insights into imaging

2024 Volume 15, Issue 1, Page(s) 62

Abstract: Gadolinium-based contrast agents (GBCA) are essential for diagnostic MRI examinations. GBCA are only used in small quantities on a per-patient basis; however, the acquisition of contrast-enhanced MRI examinations worldwide results in the use of many ... ...

Abstract	Gadolinium-based contrast agents (GBCA) are essential for diagnostic MRI examinations. GBCA are only used in small quantities on a per-patient basis; however, the acquisition of contrast-enhanced MRI examinations worldwide results in the use of many thousands of litres of GBCA per year. Data shows that these GBCA are present in sewage water, surface water, and drinking water in many regions of the world. Therefore, there is growing concern regarding the environmental impact of GBCA because of their ubiquitous presence in the aquatic environment. To address the problem of GBCA in the water system as a whole, collaboration is necessary between all stakeholders, including the producers of GBCA, medical professionals and importantly, the consumers of drinking water, i.e. the patients. This paper aims to make healthcare professionals aware of the opportunity to take the lead in making informed decisions about the use of GBCA and provides an overview of the different options for action.In this paper, we first provide a summary on the metabolism and clinical use of GBCA, then the environmental fate and observations of GBCA, followed by measures to reduce the use of GBCA. The environmental impact of GBCA can be reduced by (1) measures focusing on the application of GBCA by means of weight-based contrast volume reduction, GBCA with higher relaxivity per mmol of Gd, contrast-enhancing sequences, and post-processing; and (2) measures that reduce the waste of GBCA, including the use of bulk packaging and collecting residues of GBCA at the point of application.Critical relevance statement This review aims to make healthcare professionals aware of the environmental impact of GBCA and the opportunity for them to take the lead in making informed decisions about GBCA use and the different options to reduce its environmental burden.Key points• Gadolinium-based contrast agents are found in sources of drinking water and constitute an environmental risk.• Radiologists have a wide spectrum of options to reduce GBCA use without compromising diagnostic quality.• Radiology can become more sustainable by adopting such measures in clinical practice.
Language	English
Publishing date	2024-02-27
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	2543323-4
ISSN	1869-4101
ISSN	1869-4101
DOI	10.1186/s13244-024-01626-7
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book: Ganzkörper-Computertomographie

Prokop, Mathias / Engelke, Christoph

Spiral- und Multislice-CT ; 328 Tabellen

(RRR - Referenz-Reihe Radiologie)

2007

Author's details	Mathias Prokop ... Unter Mitarb. von C. Engelke
Series title	RRR - Referenz-Reihe Radiologie
Keywords	Tomography, X-Ray Computed ; Computertomografie
Subject	Computertomographie ; CT ; Tomometrie ; Durchstrahlungscomputertomographie ; Durchstrahlungscomputertomografie ; Transmissionscomputertomographie ; Transmissionscomputertomografie ; Computerlaminographie ; Computerlaminografie ; CAT ; Computed axial tomography ; Computertomogramm
Language	German
Size	XXIV, 1064 S. : zahlr. Ill., graph. Darst.
Edition	2., vollst. überarb. und erw. Aufl.
Publisher	Thieme
Publishing place	Stuttgart u.a.
Publishing country	Germany
Document type	Book
HBZ-ID	HT014101031
ISBN	3-13-108912-1 ; 978-3-13-108912-0
Database	Catalogue ZB MED Medicine, Health

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2006 A 6158	order for loan	Magazin
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Article ; Online: Hounsfield's Legacy.

Wildberger, Joachim Ernst / Prokop, Mathias

Investigative radiology

2020 Volume 55, Issue 9, Page(s) 556–558

Abstract: Computed tomography (CT) has evolved over decades, offering superb morphologic imaging with isotropic resolution at rapid acquisition times. The latest developments in hardware, such as photon-counting and ultrahigh-resolution detectors, together with ... ...

Abstract	Computed tomography (CT) has evolved over decades, offering superb morphologic imaging with isotropic resolution at rapid acquisition times. The latest developments in hardware, such as photon-counting and ultrahigh-resolution detectors, together with breakthroughs in software technology have further improved spatial and temporal resolution while steadily reducing radiation exposure. These achievements enable CT for functional imaging and make high-quality imaging more accessible through workflow automation. Radiomics, integrated diagnostics, and data science will further push CT applications beyond their current limits.
MeSH term(s)	Photons ; Software ; Tomography, X-Ray Computed
Language	English
Publishing date	2020-07-23
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	80345-5
ISSN	1536-0210 ; 0020-9996
ISSN (online)	1536-0210
ISSN	0020-9996
DOI	10.1097/RLI.0000000000000680
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Article: Tackling the increasing contamination of the water supply by iodinated contrast media.

Dekker, Helena M / Stroomberg, Gerard J / Prokop, Mathias

Insights into imaging

2022 Volume 13, Issue 1, Page(s) 30

Abstract: Contrast media are essential for diagnostic and interventional procedures. Iodinated contrast media are the most commonly used agents, with CT requiring the largest overall quantities. Data show that these iodinated contrast media are found in sewage ... ...

Abstract	Contrast media are essential for diagnostic and interventional procedures. Iodinated contrast media are the most commonly used agents, with CT requiring the largest overall quantities. Data show that these iodinated contrast media are found in sewage water, surface water and drinking water in many regions in the world. Because standard drinking water purification techniques only provide poor to moderate removal of iodinated contrast media, these substances pose a problem for drinking water preparation that has not yet been solved. There is a growing body of evidence supporting the negative environmental effects of iodinated contrast media via their breakdown products. The environmental impact of iodinated contrast media can be mitigated by measures focusing on the application of contrast media or the excretion of contrast media. Measures with respect to contrast application include reducing the utilization of contrast media, reducing the waste of contrast media and collecting residues of contrast media at the point of application. The amount of contrast media excreted into the sewage water can be decreased by introducing urine bags and/or special urine collection and waste-water processing techniques in the hospital. To tackle the problem of contrast media in the water system in its entirety, it is necessary for all parties involved to cooperate, from the producer of contrast medium to the consumer of drinking water. This paper aims to make health professionals aware of the opportunity to take the lead now in more conscious decisions regarding use of contrast media and gives an overview of the different perspectives for action.
Language	English
Publishing date	2022-02-24
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	2543323-4
ISSN	1869-4101
ISSN	1869-4101
DOI	10.1186/s13244-022-01175-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: The Facilitators and Barriers of the Implementation of a Clinical Decision Support System for Breast Cancer Multidisciplinary Team Meetings-An Interview Study.

Kočo, Lejla / Siebers, Carmen C N / Schlooz, Margrethe / Meeuwis, Carla / Oldenburg, Hester S A / Prokop, Mathias / Mann, Ritse M

Cancers

2024 Volume 16, Issue 2

Abstract: Background: AI-driven clinical decision support systems (CDSSs) hold promise for multidisciplinary team meetings (MDTMs). This study aimed to uncover the hurdles and aids in implementing CDSSs during breast cancer MDTMs.: Methods: Twenty-four core ... ...

Abstract	Background: AI-driven clinical decision support systems (CDSSs) hold promise for multidisciplinary team meetings (MDTMs). This study aimed to uncover the hurdles and aids in implementing CDSSs during breast cancer MDTMs. Methods: Twenty-four core team members from three hospitals engaged in semi-structured interviews, revealing a collective interest in experiencing CDSS workflows in clinical practice. All interviews were audio recorded, transcribed verbatim and analyzed anonymously. A standardized approach, 'the framework method', was used to create an analytical framework for data analysis, which was performed by two independent researchers. Results: Positive aspects included improved data visualization, time-saving features, automated trial matching, and enhanced documentation transparency. However, challenges emerged, primarily concerning data connectivity, guideline updates, the accuracy of AI-driven suggestions, and the risk of losing human involvement in decision making. Despite the complexities involved in CDSS development and integration, clinicians demonstrated enthusiasm to explore its potential benefits. Conclusions: Acknowledging the multifaceted nature of this challenge, insights into the barriers and facilitators identified in this study offer a potential roadmap for smoother future implementations. Understanding these factors could pave the way for more effective utilization of CDSSs in breast cancer MDTMs, enhancing patient care through informed decision making.
Language	English
Publishing date	2024-01-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers16020401
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Article ; Online: Optimized, Person-Centered Workflow Design for a High-Throughput Breast MRI Screening Facility-A Simulation Study.

Kočo, Lejla / Balkenende, Luuk / Appelman, Linda / Moman, Maaike R / Sponsel, Aljoscha / Schimanski, Markus / Prokop, Mathias / Mann, Ritse M

Investigative radiology

2024

Abstract: Objectives: This project aims to model an optimal scanning environment for breast magnetic resonance imaging (MRI) screening based on real-life data to identify to what extent the logistics of breast MRI can be optimized.: Materials and methods: A ... ...

Abstract	Objectives: This project aims to model an optimal scanning environment for breast magnetic resonance imaging (MRI) screening based on real-life data to identify to what extent the logistics of breast MRI can be optimized. Materials and methods: A novel concept for a breast MRI screening facility was developed considering layout of the building, workflow steps, used resources, and MRI protocols. The envisioned screening facility is person centered and aims for an efficient workflow-oriented design. Real-life data, collected from existing breast MRI screening workflows, during 62 scans in 3 different hospitals, were imported into a 3D simulation software for designing and testing new concepts. The model provided several realistic, virtual, logistical pathways for MRI screening and their outcome measures: throughput, waiting times, and other relevant variables. Results: The total average appointment time in the baseline scenario was 25:54 minutes, with 19:06 minutes of MRI room occupation. Simulated improvements consisted of optimizing processes and resources, facility layout, and scanning protocol. In the simulation, time spent in the MRI room was reduced by introducing an optimized facility layout, dockable tables, and adoption of an abbreviated MRI scanning protocol. The total average appointment time was reduced to 19:36 minutes, and in this scenario, the MRI room was occupied for 06:21 minutes. In the most promising scenario, screening of about 68 people per day (10 hours) on a single MRI scanner could be feasible, compared with 36 people per day in the baseline scenario. Conclusions: This study suggests that by optimizing workflow MRI for breast screening total appointment duration and MRI occupation can be reduced. A throughput of up to 6 people per hour may be achieved, compared with 3 people per hour in the current setup.
Language	English
Publishing date	2024-01-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	80345-5
ISSN	1536-0210 ; 0020-9996
ISSN (online)	1536-0210
ISSN	0020-9996
DOI	10.1097/RLI.0000000000001059
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Article ; Online: Tackling the increasing contamination of the water supply by iodinated contrast media

Helena M. Dekker / Gerard J. Stroomberg / Mathias Prokop

Insights into Imaging, Vol 13, Iss 1, Pp 1-

2022 Volume 9

Abstract: Abstract Contrast media are essential for diagnostic and interventional procedures. Iodinated contrast media are the most commonly used agents, with CT requiring the largest overall quantities. Data show that these iodinated contrast media are found in ... ...

Abstract	Abstract Contrast media are essential for diagnostic and interventional procedures. Iodinated contrast media are the most commonly used agents, with CT requiring the largest overall quantities. Data show that these iodinated contrast media are found in sewage water, surface water and drinking water in many regions in the world. Because standard drinking water purification techniques only provide poor to moderate removal of iodinated contrast media, these substances pose a problem for drinking water preparation that has not yet been solved. There is a growing body of evidence supporting the negative environmental effects of iodinated contrast media via their breakdown products. The environmental impact of iodinated contrast media can be mitigated by measures focusing on the application of contrast media or the excretion of contrast media. Measures with respect to contrast application include reducing the utilization of contrast media, reducing the waste of contrast media and collecting residues of contrast media at the point of application. The amount of contrast media excreted into the sewage water can be decreased by introducing urine bags and/or special urine collection and waste-water processing techniques in the hospital. To tackle the problem of contrast media in the water system in its entirety, it is necessary for all parties involved to cooperate, from the producer of contrast medium to the consumer of drinking water. This paper aims to make health professionals aware of the opportunity to take the lead now in more conscious decisions regarding use of contrast media and gives an overview of the different perspectives for action.
Keywords	Contrast media ; Environmental fate ; Water supply system ; Sustainability ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Subject code	070
Language	English
Publishing date	2022-02-01T00:00:00Z
Publisher	SpringerOpen
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Trends in the incidence of pulmonary nodules in chest computed tomography: 10-year results from two Dutch hospitals.

Hendrix, Ward / Rutten, Matthieu / Hendrix, Nils / van Ginneken, Bram / Schaefer-Prokop, Cornelia / Scholten, Ernst T / Prokop, Mathias / Jacobs, Colin

European radiology

2023 Volume 33, Issue 11, Page(s) 8279–8288

Abstract: Objective: To study trends in the incidence of reported pulmonary nodules and stage I lung cancer in chest CT.: Methods: We analyzed the trends in the incidence of detected pulmonary nodules and stage I lung cancer in chest CT scans in the period ... ...

Abstract	Objective: To study trends in the incidence of reported pulmonary nodules and stage I lung cancer in chest CT. Methods: We analyzed the trends in the incidence of detected pulmonary nodules and stage I lung cancer in chest CT scans in the period between 2008 and 2019. Imaging metadata and radiology reports from all chest CT studies were collected from two large Dutch hospitals. A natural language processing algorithm was developed to identify studies with any reported pulmonary nodule. Results: Between 2008 and 2019, a total of 74,803 patients underwent 166,688 chest CT examinations at both hospitals combined. During this period, the annual number of chest CT scans increased from 9955 scans in 6845 patients in 2008 to 20,476 scans in 13,286 patients in 2019. The proportion of patients in whom nodules (old or new) were reported increased from 38% (2595/6845) in 2008 to 50% (6654/13,286) in 2019. The proportion of patients in whom significant new nodules (≥ 5 mm) were reported increased from 9% (608/6954) in 2010 to 17% (1660/9883) in 2017. The number of patients with new nodules and corresponding stage I lung cancer diagnosis tripled and their proportion doubled, from 0.4% (26/6954) in 2010 to 0.8% (78/9883) in 2017. Conclusion: The identification of incidental pulmonary nodules in chest CT has steadily increased over the past decade and has been accompanied by more stage I lung cancer diagnoses. Clinical relevance statement: These findings stress the importance of identifying and efficiently managing incidental pulmonary nodules in routine clinical practice. Key points: • The number of patients who underwent chest CT examinations substantially increased over the past decade, as did the number of patients in whom pulmonary nodules were identified. • The increased use of chest CT and more frequently identified pulmonary nodules were associated with more stage I lung cancer diagnoses.
MeSH term(s)	Humans ; Incidence ; Solitary Pulmonary Nodule/diagnostic imaging ; Solitary Pulmonary Nodule/epidemiology ; Multiple Pulmonary Nodules/diagnostic imaging ; Multiple Pulmonary Nodules/epidemiology ; Tomography, X-Ray Computed/methods ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/epidemiology
Language	English
Publishing date	2023-06-20
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1085366-2
ISSN	1432-1084 ; 0938-7994 ; 1613-3749
ISSN (online)	1432-1084
ISSN	0938-7994 ; 1613-3749
DOI	10.1007/s00330-023-09826-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

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