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Article ; Online: CORONA-steps for tracheotomy in COVID-19 patients: A staff-safe method for airway management.

Haen, Pierre / Caruhel, Jean-Baptiste / Laversanne, Sophie / Cordier, Pierre-Yves

2020 Volume 105, Page(s) 104729

MeSH term(s)	Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Tracheostomy ; Tracheotomy
Keywords	covid19
Language	English
Publishing date	2020-04-20
Publishing country	England
Document type	Letter ; Comment
ZDB-ID	1120465-5
ISSN	1879-0593 ; 0964-1955 ; 1368-8375
ISSN (online)	1879-0593
ISSN	0964-1955 ; 1368-8375
DOI	10.1016/j.oraloncology.2020.104729
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Zs.A 4869: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.A 456: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Comparison of three surgical techniques of posterolateral knee reconstruction: A cadaver study.

Pioger, Charles / Bouché, Pierre-Alban / Haen, Thomas-Xavier / Pujol, Nicolas

Orthopaedics & traumatology, surgery & research : OTSR

2022 Volume 108, Issue 8, Page(s) 103414

Abstract: Background: Injuries to the posterolateral corner (PLC) of the knee are often overlooked but, require reconstruction in order to restore stability in varus and external rotation. Among the many anatomic and non-anatomic PLC reconstruction techniques ... ...

Abstract	Background: Injuries to the posterolateral corner (PLC) of the knee are often overlooked but, require reconstruction in order to restore stability in varus and external rotation. Among the many anatomic and non-anatomic PLC reconstruction techniques available, the modified Larson (mLR), LaPrade (LPR) and Versailles reconstruction (VR) procedures are widely used. Hypothesis: The hypothesis was that anatomic PLC reconstruction (VR and LPR procedures) provides better restoration and control of external rotation. Patients and methods: Fifteen fresh-frozen cadaveric knees were tested to compare the 3 procedures. Varus laxity on stress radiographs in full knee extension and external rotatory laxity on dial test at 30° flexion were quantified at 3 phases: intact knee, PLC sectioned and PLC reconstructed. Results: Mean varus laxity did not differ significantly between techniques in intact knees (p=.14), after PLC sectioning (p=.14) or after PLC reconstruction (p=.17). After PLC reconstruction, varus laxity was restored, with no statistical difference between mLR, VR and LPR compared to intact test values (respectively, -1.0, -1.3 and -1.5; p=.98). In all 3 groups, mean external rotation laxity on dial test at 30° flexion did not significantly differ between intact knees (p=.32) and after PLC sectioning (p=.15). After PLC reconstruction, the mLR technique was significantly less effective in restoring rotational stability than the VR and LPR techniques (p=.025). Discussion: The VR technique provided similar outcomes to LPR for restoring stability in varus and external rotation. The 2 "anatomic" reconstruction procedures (VR and LPR) were significantly more effective than the modified Larson technique for external rotation control, confirming the study hypothesis. Consequently, it remains preferable to use anatomic techniques in multiligament injuries involving the PLC. Level of evidence: IV, cadaver study.
MeSH term(s)	Humans ; Joint Instability/surgery ; Biomechanical Phenomena ; Knee Joint/surgery ; Range of Motion, Articular ; Cadaver
Language	English
Publishing date	2022-09-17
Publishing country	France
Document type	Journal Article
ISSN	1877-0568
ISSN (online)	1877-0568
DOI	10.1016/j.otsr.2022.103414
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Article ; Online: Head Face and Neck Surgeon Deployment in the New French Role 2: The Damage Control Resuscitation and Surgical Team.

Fawaz, Rayan / Dagain, Arnaud / Pons, Yoann / Haen, Pierre / Froussart, Françoise / Caruhel, Jean Baptiste

Military medicine

2022 Volume 188, Issue 9-10, Page(s) e2868–e2873

Abstract: Introduction: High-intensity conflict is back after decades of asymmetric warfare. With the increase in the incidence of head, face, and neck (HFN) injuries, the French Medical Military Service has decided to deploy HFN surgeons in the new French Role 2: ...

Abstract	Introduction: High-intensity conflict is back after decades of asymmetric warfare. With the increase in the incidence of head, face, and neck (HFN) injuries, the French Medical Military Service has decided to deploy HFN surgeons in the new French Role 2: the Damage Control, Resuscitation, and Surgical Team (DCRST). This study aims to provide an overview of HFN French surgeons from their initial training, including the surgical skills required, to their deployment on the DCRST. Materials and methods: The DCRST is a tactical mobile medico-surgical structure with several configurations depending on the battlefield, mission, and flux of casualties. It represents the new French paradigm for the management of combat casualties, including HFN injuries. Results: The HFN's military surgeon training starts during residency with rotation in the different subspecialties. The HFN surgeon follows a training course called "The French Course for Deployment Surgery" that provides sufficient background to manage polytrauma, including HFN facilities on modern warfare. We have reviewed the main surgical procedures required for an HFN military surgeon. Conclusion: The systematic deployment of HFN surgeons in Role 2 is a specificity of the French army as well as the HFN surgeon's training.Currently, the feedback from an asymmetric conflict is encouraging. However, it will have to innovate to adapt to modern warfare.
MeSH term(s)	Humans ; Military Medicine/education ; Military Personnel/education ; Multiple Trauma ; Neck Injuries/surgery ; Surgeons
Language	English
Publishing date	2022-10-19
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	391061-1
ISSN	1930-613X ; 0026-4075
ISSN (online)	1930-613X
ISSN	0026-4075
DOI	10.1093/milmed/usac329
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Article: CORONA-steps for tracheotomy in COVID-19 patients: A staff-safe method for airway management

Haen, Pierre / Caruhel, Jean-Baptiste / Laversanne, Sophie / Cordier, Pierre-Yves

Oral Oncol

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #88359
Database	COVID19

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Article ; Online: CORONA-steps for tracheotomy in COVID-19 patients

Haen, Pierre / Caruhel, Jean-Baptiste / Laversanne, Sophie / Cordier, Pierre-Yves

Oral Oncology

A staff-safe method for airway management

2020 Volume 105, Page(s) 104729

Keywords	Cancer Research ; Oral Surgery ; Oncology ; covid19
Language	English
Publisher	Elsevier BV
Publishing country	us
Document type	Article ; Online
ZDB-ID	1120465-5
ISSN	1879-0593 ; 0964-1955 ; 1368-8375
ISSN (online)	1879-0593
ISSN	0964-1955 ; 1368-8375
DOI	10.1016/j.oraloncology.2020.104729
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Zs.A 4869: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.A 456: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Health workers' safety during tracheostomy in COVID-19 patients: Homemade protective screen.

Cordier, Pierre-Yves / De La Villeon, Bruno / Martin, Edouard / Goudard, Yvain / Haen, Pierre

Head & neck

2020 Volume 42, Issue 7, Page(s) 1361–1362

Abstract: As an aerosol and droplets generating procedure, tracheostomy increases contamination risks for health workers in the coronavirus disease context. To preserve the health care system capacity and to limit virus cross-transmission, protecting caregivers ... ...

Abstract	As an aerosol and droplets generating procedure, tracheostomy increases contamination risks for health workers in the coronavirus disease context. To preserve the health care system capacity and to limit virus cross-transmission, protecting caregivers against coronavirus infection is of critical importance. We report the use of external fixator equipment to set up a physical interface between the patient's neck and the caregiver performing a tracheostomy in COVID-19 patients. Once the metal frame set in place, it is wrapped with a single-use clear and sterile cover for surgical C-arm. This installation is simple, easy, and fast to achieve and can be carried out with inexpensive material available in every hospital. This physical interface is an additional safety measure that prevents the direct projection of secretions or droplets. It should, of course, only be considered as a complement to strict compliance with barrier precautions and personal protective equipment.
MeSH term(s)	COVID-19 ; China ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Equipment Design ; Female ; Health Personnel/statistics & numerical data ; Humans ; Infection Control/methods ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Male ; Occupational Health ; Pandemics/prevention & control ; Pandemics/statistics & numerical data ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Protective Devices/statistics & numerical data ; Tracheostomy/instrumentation ; Tracheostomy/methods
Keywords	covid19
Language	English
Publishing date	2020-04-29
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	645165-2
ISSN	1097-0347 ; 0148-6403 ; 1043-3074
ISSN (online)	1097-0347
ISSN	0148-6403 ; 1043-3074
DOI	10.1002/hed.26222
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Oral Squamous Cell Carcinoma Is Associated with a Low Thrombosis Risk Due to Storage Pool Deficiency in Platelets.

Haen, Pierre / Crescence, Lydie / Mege, Diane / Altié, Alexandre / Dubois, Christophe / Panicot-Dubois, Laurence

Biomedicines

2021 Volume 9, Issue 3

Abstract: Venous thrombo-embolism (VTE) disease is the second most common cause of mortality in cancer patients, and evaluation and prevention of thrombosis risk is essential. VTE-associated risk varies according to the type of tumor disease. Oral cancer is the ... ...

Abstract	Venous thrombo-embolism (VTE) disease is the second most common cause of mortality in cancer patients, and evaluation and prevention of thrombosis risk is essential. VTE-associated risk varies according to the type of tumor disease. Oral cancer is the most frequent type of head and neck cancer, and it represents approximately 2.1% of all cancers worldwide. Most tumors are squamous cell carcinomas and are mainly due to tobacco and alcohol abuse. VTE risk associated with oral squamous cell carcinoma (OSCC) is low. However, many studies have shown that OSCC has the following biological features of cancers associated with a high thrombosis risk: modified thrombosis and fibrinolysis mechanisms; strong expression of procoagulant proteins; secretion of procoagulant microparticles; and production of procoagulant cytokines. Using an original mouse model of tongue squamous cell carcinoma, our study aimed to clarify this paradoxical situation. First, we showed that OSCC tumors have a pro-aggregatory phenotype and a high local thrombosis risk. Second, we found that tongue tumor mice do not have an elevated systemic thrombosis risk (the risk of an "at distance" thrombosis event such as lower extremity deep venous thrombosis or pulmonary embolism) and even show a reduction in risk. Third, we demonstrated that tongue tumor mice show a reduction in platelet reactivity, which explains the low systemic thrombosis risk. Finally, we found that tongue tumor mice present granule pool deficiency, thereby explaining the reduction in platelet reactivity and systemic thrombosis risk.
Language	English
Publishing date	2021-02-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720867-9
ISSN	2227-9059
ISSN	2227-9059
DOI	10.3390/biomedicines9030228
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Clinical validation of an elastin-derived trifunctional peptide for skin regeneration.

Abraham, Jean-Daniel / Vaissière, Anais / Desouches, Christophe / Thiery, Gaetan / Bertrand, Baptiste / Alfandari, Bruno / Courtois, Ivan / Azencot, Armand / Casoli, Vincent / Haen, Pierre / Colson, Thomas / Hornebeck, William / Ritter, Didier

American journal of translational research

2023 Volume 15, Issue 7, Page(s) 4620–4628

Abstract: Aging is associated with progressive skin fragility, characterized in part by extracellular matrix (ECM) fragmentation. This degradation produces matrikines which have an impact on ECM rremodeling. Our group previously designed and characterized a ... ...

Abstract	Aging is associated with progressive skin fragility, characterized in part by extracellular matrix (ECM) fragmentation. This degradation produces matrikines which have an impact on ECM rremodeling. Our group previously designed and characterized a trifunctional peptide (TFP), constituted of i) an elastokine motif (VGVAPG) Objective: In the present study, TFP properties were evaluated in a clinical assay. Methods: Twenty-two volunteers applied a TFP-based cream on one hemi-face and a placebo-based cream on the other hemi-face, twice a day during 28 days, before undergoing a surgical lifting. Cutometry and skin relief measurements were performed at days 0 and 28, and skin explants from lifting surgery were used for histological analyses. Results: Cutometry and skin relief measurements reveal TFP firming properties and wrinkle depth decrease in 28 days on TFP- as compared to placebo-treated hemi-faces. These results are confirmed by histological analyses showing an increase of the ratio between basal lamina and stratum corneum. Furthermore, immunostaining of collagen reveals a modification of the ratio between type I and III collagens. Conclusion: The combined analysis of phenotypic and histologic parameters demonstrates a reorganization of the ECM towards a regenerative profile upon TFP treatment.
Language	English
Publishing date	2023-07-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2471058-1
ISSN	1943-8141
ISSN	1943-8141
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Health workers' safety during tracheostomy in COVID ‐19 patients

Cordier, Pierre‐Yves / De La Villeon, Bruno / Martin, Edouard / Goudard, Yvain / Haen, Pierre

Head & Neck

Homemade protective screen

2020 Volume 42, Issue 7, Page(s) 1361–1362

Keywords	Otorhinolaryngology ; covid19
Language	English
Publisher	Wiley
Publishing country	us
Document type	Article ; Online
ISSN	1043-3074
DOI	10.1002/hed.26222
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Early Evaluation of a New French Surgery Course in the Best Practice of Dealing With Major Incidents and Mass Casualty Events.

Fischer, Juliette / Barbois, Sandrine / Quesada, Jean-Louis / Boddaert, Guillaume / Haen, Pierre / Bertani, Antoine / Duhamel, Patrick / Delmas, Jean-Marc / Lechevallier, Eric / Piolat, Christian / Rongieras, Frédéric / Tresallet, Christophe / Balandraud, Paul / Arvieux, Catherine

Journal of surgical education

2023 Volume 80, Issue 9, Page(s) 1253–1267

Abstract: Objective: The main objective of this study is to evaluate the impact of a nationwide 5-month course aimed to prepare surgeons for Major Incidents through the acquisition of key knowledge and competencies. Learners' satisfaction was also measured as a ... ...

Abstract	Objective: The main objective of this study is to evaluate the impact of a nationwide 5-month course aimed to prepare surgeons for Major Incidents through the acquisition of key knowledge and competencies. Learners' satisfaction was also measured as a secondary objective. Design: This course was evaluated thanks to various teaching efficacy metrics, mainly based on Kirkpatrick's hierarchy in medical education. Gain in knowledge of participants was evaluated by multiple-choice tests. Self-reported confidence was measured with 2 detailed pre and post training questionnaires. Setting: Creation in 2020 of a nationwide, optional and comprehensive Surgical Training in War and Disaster Situation as part of the French surgery residency program. In 2021, data was gathered regarding the impact of the course on participants' knowledge and competencies. Participants: The study included 26 students in the 2021 cohort (13 residents and 13 practitioners). Results: Mean scores were significantly higher in the post-test compared to the pre-test, showing significant increase in participants' knowledge during the course: 73,3% vs. 47,3% respectively (p ≤ 0.001). Average learners' confidence scores to perform technical procedures showed at least a +1-point increase on the Likert scale for 65% of items tested (p ≤ 0.001). 89% of items showed at least a +1-point increase on the Likert scale when it came to average learners' confidence score on dealing with complicated situations (p ≤ 0.001). Our post-training satisfaction survey showed that 92% of all participants have noticed the impact of the course on their daily practice. Conclusion: Our study shows that the third level of Kirkpatrick's hierarchy in medical education was reached. This course therefore appears to be meeting the objectives set by the Ministry of Health. Being only 2 years old, it is on the road to gathering momentum and further development.
MeSH term(s)	Humans ; Child, Preschool ; Mass Casualty Incidents ; Students ; Surveys and Questionnaires ; Education, Medical ; Personal Satisfaction
Language	English
Publishing date	2023-07-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	2277538-9
ISSN	1878-7452 ; 1931-7204
ISSN (online)	1878-7452
ISSN	1931-7204
DOI	10.1016/j.jsurg.2023.06.011
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