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Book: Minimally invasive spine surgery

Phillips, Frank M.

surgical techniques and disease management

2014

Author's details	Frank M. Phillips ...ed
Keywords	Spine--Surgery ; Endoscopic surgery ; Laparoscopic surgery
Language	English
Size	XVII, 473 S. : Ill., graph. Darst., 24 cm
Publisher	Springer
Publishing place	New York u.a.
Publishing country	United States
Document type	Book
HBZ-ID	HT018328857
ISBN	978-1-4614-5673-5 ; 9781461456742 ; 1-4614-5673-8 ; 1461456746
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

Shelf mark	Loan status	Location
2014 A 2817	available for loan (reading room)	Lesesaal EG

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Book: Treatment of complex cervical spine disorders

Phillips, Frank M.

(The orthopedic clinics of North America ; 43,1)

2012

Author's details	guest ed. Frank M. Phillips
Series title	The orthopedic clinics of North America ; 43,1
Collection
Language	English
Size	XIII, 154 S. : zahlr. Ill.
Publisher	Saunders an imprint of Elsevier
Publishing place	Philadelphia, PA
Publishing country	United States
Document type	Book
HBZ-ID	HT017090490
ISBN	978-1-4557-3904-2 ; 1-4557-3904-9
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

Shelf mark	Loan status	Location
Se 118 -43,1-	verfügbar in Königswinter	Königswinter

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Book: <The> lumbar intervertebral disc

Phillips, Frank M.

2009

Author's details	Frank M. Phillips
Keywords	Intervertebral Disk ; Lumbosacral Region
Language	English
Size	XIX, 305 S. : Ill., graph. Darst.
Publisher	Thieme
Publishing place	New York u.a.
Publishing country	United States
Document type	Book
HBZ-ID	HT016076132
ISBN	978-1-60406-048-5 ; 1-60406-048-4
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

Shelf mark	Loan status	Location
2009 A 4853	order for loan	Magazin

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Article ; Online: Postoperative Spinal Hematoma and Seroma.

Butler, Alexander J / Mohile, Neil / Phillips, Frank M

The Journal of the American Academy of Orthopaedic Surgeons

2023 Volume 31, Issue 17, Page(s) 908–913

Abstract: Fluid collections after spine surgery are rare complications, although potentially grave, and may be broadly grouped into two major categories. Symptomatic postoperative epidural hematomas have some known risk factors and can present with a widely ... ...

Abstract	Fluid collections after spine surgery are rare complications, although potentially grave, and may be broadly grouped into two major categories. Symptomatic postoperative epidural hematomas have some known risk factors and can present with a widely variable profile of signs and symptoms. Treatment involves emergent surgical evacuation to reduce the risk of permanent neurologic deficit. Postoperative seroma may lead to disruption of wound healing and deep infection and has been associated with the use of recombinant human bone mineral protein. These diagnoses may present diagnostic challenges; thorough understanding of the involved pathophysiology, meticulous clinical evaluation, and radiographic interpretation are critical to appropriate management and optimal outcome.
MeSH term(s)	Humans ; Seroma/therapy ; Seroma/complications ; Retrospective Studies ; Spine/surgery ; Hematoma/etiology ; Spinal Cord Diseases/etiology ; Postoperative Complications/surgery
Language	English
Publishing date	2023-04-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	1200524-1
ISSN	1940-5480 ; 1067-151X
ISSN (online)	1940-5480
ISSN	1067-151X
DOI	10.5435/JAAOS-D-22-01022
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Zs.A 4048: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Applications of Augmented Reality in Orthopaedic Spine Surgery.

Shahzad, Hania / Bhatti, Nazihah S / Phillips, Frank M / Khan, Safdar N

The Journal of the American Academy of Orthopaedic Surgeons

2023 Volume 31, Issue 17, Page(s) e601–e609

Abstract: The application of augmented reality (AR) in surgical settings has primarily been as a navigation tool in the operating room because of its ease of use and minimal effect on surgical procedures. The surgeon can directly face the surgical field while ... ...

Abstract	The application of augmented reality (AR) in surgical settings has primarily been as a navigation tool in the operating room because of its ease of use and minimal effect on surgical procedures. The surgeon can directly face the surgical field while viewing 3D anatomy virtually, thus reducing the need to look at an external display, such as a navigation system. Applications of AR are being explored in spine surgery. The basic principles of AR include data preparation, registration, tracking, and visualization. Current literature provides sufficient preclinical and clinical data evidence for the use of AR technology in spine surgery. AR systems are efficient assistive devices, providing greater accuracy for insertion points, more comfort for surgeons, and reduced operating time. AR technology also has beneficial applications in surgical training, education, and telementorship for spine surgery. However, costs associated with specially designed imaging equipment and physicians' comfort in using this technology continue to remain barriers to its adoption. As this technology evolves to a more widespread use, future applications will be directed by the cost-effectiveness of AR-assisted surgeries.
MeSH term(s)	Humans ; Augmented Reality ; Orthopedics ; Surgery, Computer-Assisted/methods ; Spine/surgery ; Orthopedic Procedures/methods
Language	English
Publishing date	2023-04-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	1200524-1
ISSN	1940-5480 ; 1067-151X
ISSN (online)	1940-5480
ISSN	1067-151X
DOI	10.5435/JAAOS-D-23-00023
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Zs.A 4048: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Delayed Infection After Cervical Disc Arthroplasty: A Case Report and Review of the Literature.

Federico, Vincent P / Zavras, Athan G / Vucicevic, Rajko S / Salazar, Luis M / An, Howard S / Colman, Matthew W / Phillips, Frank M

Clinical spine surgery

2024

Abstract: Study design: Case report and literature review.: Objective: To report the relatively rare complication of delayed infection after cervical disc arthroplasty (CDA).: Background: Delayed infection of the M6 device has been a rarely reported ... ...

Abstract	Study design: Case report and literature review. Objective: To report the relatively rare complication of delayed infection after cervical disc arthroplasty (CDA). Background: Delayed infection of the M6 device has been a rarely reported complication, with all cases described outside of the United States. The reliability of positive intraoperative cultures remains an ongoing debate. Methods: Cases were reviewed, and findings were summarized. A literature review was performed and discussed, with special consideration to current reports of delayed M6 infection, etiology, and utility of intraoperative cultures. Results: We present a case of delayed infection 6 years after primary 1-level CDA with the M6 device. At revision surgery, gross purulence was encountered. Intraoperative cultures finalized with Staphylococcus epidermidis and Cutibacterium acnes. The patient was revised with removal of the M6 and conversion to anterior cervical discectomy and fusion. A prolonged course of intravenous antibiotics was followed by an oral course for suppression. At the final follow-up, the patient's preoperative symptoms had resolved. Conclusion: Delayed infection after CDA is a rare complication, with ongoing debate regarding the reliability of positive cultures. We describe an infected M6 and demonstrate the utility of implant removal, conversion to anterior cervical discectomy and fusion, and long-term antibiotics as definitive treatment. Level of evidence: Level V-case report and literature review.
Language	English
Publishing date	2024-04-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	2849646-2
ISSN	2380-0194 ; 2380-0186
ISSN (online)	2380-0194
ISSN	2380-0186
DOI	10.1097/BSD.0000000000001618
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Zs.A 2427: Show issues

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Article ; Online: Proposal for a classification system of radiographic bone changes after cervical disc replacement.

Khachatryan, Armen / Phillips, Frank M / Lanman, Todd H / Andersson, Gunnar B / Jacobs, Joshua J / Kurtz, Steven M

Journal of orthopaedic surgery and research

2024 Volume 19, Issue 1, Page(s) 218

Abstract: Background: The goal of this study is to propose a classification system with a common nomenclature for radiographic observations of periprosthetic bone changes following cTDR.: Methods: Aided by serial plain radiographs from recent cTDR cases (34 ... ...

Abstract	Background: The goal of this study is to propose a classification system with a common nomenclature for radiographic observations of periprosthetic bone changes following cTDR. Methods: Aided by serial plain radiographs from recent cTDR cases (34 patients; 44 devices), a panel of experts assembled for the purpose of creating a classification system to aid in reproducibly and accurately identifying bony changes and assessing cTDR radiographic appearance. Subdividing the superior and inferior vertebral bodies into 3 equal sections, observed bone loss such as endplate rounding, cystic erosion adjacent to the endplate, and cystic erosion not adjacent to the endplate, is recorded. Determining if bone loss is progressive, based on serial radiographs, and estimating severity of bone loss (measured by the percentage of end plate involved) is recorded. Additional relevant bony changes and device observations include radiolucent lines, heterotopic ossification, vertebral body olisthesis, loss of core implant height, and presence of device migration, and subsidence. Results: Serial radiographs from 19 patients (25 devices) implanted with a variety of cTDR designs were assessed by 6 investigators including clinicians and scientists experienced in cTDR or appendicular skeleton joint replacement. The overall agreement of assessments ranged from 49.9% (95% bootstrap confidence interval 45.1-73.1%) to 94.7% (95% CI 86.9-100.0%). There was reasonable agreement on the presence or absence of bone loss or radiolucencies (range: 58.4% (95% CI 51.5-82.7%) to 94.7% (95% CI 86.9-100.0%), as well as in the progression of radiolucent lines (82.9% (95% CI 74.4-96.5%)). Conclusions: The novel classification system proposed demonstrated good concordance among experienced investigators in this field and represents a useful advancement for improving reporting in cTDR studies.
MeSH term(s)	Humans ; Treatment Outcome ; Diskectomy ; Total Disc Replacement ; Cervical Vertebrae/diagnostic imaging ; Cervical Vertebrae/surgery ; Neck ; Intervertebral Disc Degeneration/surgery
Language	English
Publishing date	2024-04-03
Publishing country	England
Document type	Journal Article
ZDB-ID	2252548-8
ISSN	1749-799X ; 1749-799X
ISSN (online)	1749-799X
ISSN	1749-799X
DOI	10.1186/s13018-024-04679-y
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Article ; Online: Deep phenotyping the cervical spine: automatic characterization of cervical degenerative phenotypes based on T2-weighted MRI.

Niemeyer, Frank / Galbusera, Fabio / Tao, Youping / Phillips, Frank M / An, Howard S / Louie, Philip K / Samartzis, Dino / Wilke, Hans-Joachim

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

2023 Volume 32, Issue 11, Page(s) 3846–3856

Abstract: Purpose: Radiological degenerative phenotypes provide insight into a patient's overall extent of disease and can be predictive for future pathological developments as well as surgical outcomes and complications. The objective of this study was to ... ...

Abstract	Purpose: Radiological degenerative phenotypes provide insight into a patient's overall extent of disease and can be predictive for future pathological developments as well as surgical outcomes and complications. The objective of this study was to develop a reliable method for automatically classifying sagittal MRI image stacks of cervical spinal segments with respect to these degenerative phenotypes. Methods: We manually evaluated sagittal image data of the cervical spine of 873 patients (5182 motion segments) with respect to 5 radiological phenotypes. We then used this data set as ground truth for training a range of multi-class multi-label deep learning-based models to classify each motion segment automatically, on which we then performed hyper-parameter optimization. Results: The ground truth evaluations turned out to be relatively balanced for the labels disc displacement posterior, osteophyte anterior superior, osteophyte posterior superior, and osteophyte posterior inferior. Although we could not identify a single model that worked equally well across all the labels, the 3D-convolutional approach turned out to be preferable for classifying all labels. Conclusions: Class imbalance in the training data and label noise made it difficult to achieve high predictive power for underrepresented classes. This shortcoming will be mitigated in the future versions by extending the training data set accordingly. Nevertheless, the classification performance rivals and in some cases surpasses that of human raters, while speeding up the evaluation process to only require a few seconds.
MeSH term(s)	Humans ; Osteophyte ; Cervical Vertebrae/surgery ; Neck ; Radiography ; Magnetic Resonance Imaging/methods
Language	English
Publishing date	2023-08-29
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1115375-1
ISSN	1432-0932 ; 0940-6719
ISSN (online)	1432-0932
ISSN	0940-6719
DOI	10.1007/s00586-023-07909-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Preserving privacy in big data research: the role of federated learning in spine surgery.

Shahzad, Hania / Veliky, Cole / Le, Hai / Qureshi, Sheeraz / Phillips, Frank M / Javidan, Yashar / Khan, Safdar N

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

2024

Abstract: Purpose: Integrating machine learning models into electronic medical record systems can greatly enhance decision-making, patient outcomes, and value-based care in healthcare systems. Challenges related to data accessibility, privacy, and sharing can ... ...

Abstract	Purpose: Integrating machine learning models into electronic medical record systems can greatly enhance decision-making, patient outcomes, and value-based care in healthcare systems. Challenges related to data accessibility, privacy, and sharing can impede the development and deployment of effective predictive models in spine surgery. Federated learning (FL) offers a decentralized approach to machine learning that allows local model training while preserving data privacy, making it well-suited for healthcare settings. Our objective was to describe federated learning solutions for enhanced predictive modeling in spine surgery. Methods: The authors reviewed the literature. Results: FL has promising applications in spine surgery, including telesurgery, AI-based prediction models, and medical image segmentation. Implementing FL requires careful consideration of infrastructure, data quality, and standardization, but it holds the potential to revolutionize orthopedic surgery while ensuring patient privacy and data control. Conclusions: Federated learning shows great promise in revolutionizing predictive modeling in spine surgery by addressing the challenges of data privacy, accessibility, and sharing. The applications of FL in telesurgery, AI-based predictive models, and medical image segmentation have demonstrated their potential to enhance patient outcomes and value-based care.
Language	English
Publishing date	2024-02-25
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	1115375-1
ISSN	1432-0932 ; 0940-6719
ISSN (online)	1432-0932
ISSN	0940-6719
DOI	10.1007/s00586-024-08172-2
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Article ; Online: Prosthesis design and likelihood of achieving physiological range of motion after cervical disc arthroplasty: Analysis of range of motion data from 1,173 patients from 7 IDE clinical trials.

Patwardhan, Avinash G / Havey, Robert M / Phillips, Frank M / Zigler, Jack E / Coric, Domagoj / Guyer, Richard / Lanman, Todd / Muriuki, Muturi G

The spine journal : official journal of the North American Spine Society

2024

Abstract: Background context: The functional goals of cervical disc arthroplasty (CDA) are to restore enough range of motion (ROM) to reduce the risk of accelerated adjacent segment degeneration but limit excessive motion to maintain a biomechanically stable ... ...

Abstract	Background context: The functional goals of cervical disc arthroplasty (CDA) are to restore enough range of motion (ROM) to reduce the risk of accelerated adjacent segment degeneration but limit excessive motion to maintain a biomechanically stable index segment. This motion-range is termed the "Physiological mobility range." Clinical studies report postoperative ROM averaged over all study subjects but they do not report what proportion of reconstructed segments yield ROM in the Physiological mobility range following CDA surgery. Purpose: To calculate the proportion of reconstructed segments that yield flexion-extension ROM (FE-ROM) in the Physiological mobility range (defined as 5-16 degrees) by analyzing the 24-month postoperative data reported by clinical trials of various cervical disc prostheses. Study design/setting: Analysis of 24-month postoperative FE-ROM data from clinical trials. Patient sample: Data from 1,173 patients from single-level disc replacement clinical trials of 7 cervical disc prostheses. Outcome measures: 24-month postoperative index-level FE-ROM. Methods: The FE-ROM histograms reported in Food and Drug Administration-Investigational Device Exemption (FDA-IDE) submissions and available for this analysis were used to calculate the frequencies of implanted levels with postoperative FE-ROM in the following motion-ranges: Hypomobile [0-4 degrees], Physiological [5-16 degrees], and Hypermobile [≥17 degrees]. The ROM histograms also allowed calculation of the average ROM of implanted segments in each of the 3 motion-ranges. Results: Only 762 of 1,173 patients (implanted levels) yielded 24-month post-CDA FE-ROM in the physiological mobility range [5-16 degrees]. The proportions ranged from 60% to 79% across the 7 disc-prostheses, with an average of 65.0%±6.2%. Three-hundred and two (302) of 1,173 implanted levels yielded ROM in the 0-4-degree range. The proportions ranged from 15% to 38% with an average of 25.7%±8.9%. One-hundred and nine (109) of 1,173 implanted levels yielded ROM of ≥17 degrees with a range of 2%-21% and an average proportion of 9.3%±7.9%. The prosthesis with built-in stiffness due to its nucleus-annulus design yielded the highest proportion (103/131, 79%) of implanted segments in the physiological mobility range, compared to the cohort average of 65% (p<.01). Sixty-five of the 350 (18.6%) discs implanted with the 2 mobile-core designs in this cohort yielded ROM≥17 degrees as compared to the cohort average of 9.3% (109/1,173) (p<.05). At 2-year post-CDA, the "hypomobile" segments moved on average 2.4±1.2 degrees, those in the "physiological-mobility" group moved 9.4±3.2 degrees, and the hypermobile segments moved 19.6±2.6 degrees. Conclusions: Prosthesis design significantly influenced the likelihood of achieving FE-ROM in the physiological mobility range, while avoiding hypomobility or hypermobility (p<.01). Postoperative ROM averaged over all study subjects provides incomplete information about the prosthesis performance - it does not tell us how many implanted segments achieve physiological mobility and how many end up with hypomobility or hypermobility. We conclude that the proportion of index levels achieving post-CDA motions in the physiological mobility range (5-16 degrees) is a more useful outcome measure for future clinical trials.
Language	English
Publishing date	2024-01-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	2037072-6
ISSN	1878-1632 ; 1529-9430
ISSN (online)	1878-1632
ISSN	1529-9430
DOI	10.1016/j.spinee.2024.01.015
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