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  1. Book ; Online: Bioactive Molecules from Marine Microorganisms

    Mazur-Marzec, Hanna / Toruńska-Sitarz, Anna

    2021  

    Keywords Medicine ; marine-derived fungus ; Aspergillus terreus ; thiodiketopiperazines ; dihydroisocoumarins ; Epicoccum nigrum ; deep-sea-derived fungus ; diketopiperazine enantiomers ; cytotocxic activity ; diatoms ; marine biotechnology ; anti-inflammatory ; drug discovery ; Cylindrotheca closterium ; mangrove Streptomyces ; genetic dereplication ; anti-microbial ; antiproliferative ; endophyte fungus ; Aspergillus versicolor ; diketopiperazines ; ECD calculation ; enantiomers ; bianthraquinones ; meroterpenoids ; anti-inflammatory activity ; Stemphylium sp ; cyanobacteria ; nostocyclopeptides ; Nostoc ; ncp gene cluster ; nonribosomal peptide synthetase ; aeruginosamides ; Limnoraphis ; cytotoxicity ; oligopeptide ; microviridin ; biotechnology ; ecology ; Penicillium citrinum ; chromone derivatives ; anti-cancer activity
    Size 1 electronic resource (172 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel, Switzerland
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021043922
    ISBN 9783036506210 ; 3036506217
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: The Cultural Identity and Education of University Students in Selected East-Central Countries : A Polish-Czech Comparative Study (Edition 1)

    Ogrodzka-Mazur, Ewa / Szafrańska, Anna / Malach, Josef / Chmura, Milan

    2021  

    Keywords Higher & further education, tertiary education ; Education ; Higher
    Size 1 Online-Ressource
    Publisher V&R unipress
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021048071
    ISBN 9783737012546 ; 3737012547
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online ; Thesis: Opportunities and Challenges for FDM 3D Printed Oral Dosage Forms for Personalized Medicine

    Mazur, Hellen [Verfasser] / Breitkreutz, Jörg [Gutachter] / Seidlitz, Anne [Gutachter]

    2023  

    Author's details Hellen Mazur ; Gutachter: Jörg Breitkreutz, Anne Seidlitz
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language English
    Publisher Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf
    Publishing place Düsseldorf
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  4. Article: How to approach and take care of minor adolescents whose situations raise ethical dilemmas? a position paper of the European academy of pediatrics.

    Michaud, Pierre-André / Takeuchi, Yusuke-Leo / Mazur, Artur / Hadjipanayis, Adamos A / Ambresin, Anne-Emmanuelle

    Frontiers in pediatrics

    2023  Volume 11, Page(s) 1120324

    Abstract: In the care of adolescents, health care providers often face situations raising ethical concerns or dilemmas, such as refusal of a treatment or hospitalization, or request of confidentiality while engaging in risky behaviors or facing unplanned pregnancy. ...

    Abstract In the care of adolescents, health care providers often face situations raising ethical concerns or dilemmas, such as refusal of a treatment or hospitalization, or request of confidentiality while engaging in risky behaviors or facing unplanned pregnancy. This position paper provides concrete avenues as how to assess the adolescent's capacity for autonomous decision making, e.g. the patient's competence in a specific situation, and how to elicit informed choice or consent. To do so, professionals need to be sensitized and trained as how to assess the cognitive and socio-psychological development of the young patient. Another challenge for the health professionals is to balance the needs to support patient's autonomy while offering secure guidance and protection if needed. To optimize such a process, they establish a climate of trust and empathy that will allow the patient to participate freely in the decision. In addition, especially when the decisions have potentially important consequences on the health and life, the professionals include, with the adolescent's permission, parents, caregivers or other significant adults, as well as they may request the opinion of other members of the health care team or expert colleagues such as ethicists.
    Language English
    Publishing date 2023-06-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2023.1120324
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Impact of Median MELD at Transplant Minus 3 National Policy on Quality of Transplanted Livers for Patients With and Without Hepatocellular Carcinoma.

    Mazur, Rafal D / Cron, David C / Chang, David C / Yeh, Heidi / Dageforde, Leigh Anne D

    Transplantation

    2023  Volume 108, Issue 1, Page(s) 204–214

    Abstract: Background: Patients with hepatocellular carcinoma (HCC) have been overprioritized in the deceased donor liver allocation system. The United Network for Organ Sharing adopted a policy in May 2019 that limited HCC exception points to the median Model for ...

    Abstract Background: Patients with hepatocellular carcinoma (HCC) have been overprioritized in the deceased donor liver allocation system. The United Network for Organ Sharing adopted a policy in May 2019 that limited HCC exception points to the median Model for End-Stage Liver Disease at transplant in the listing region minus 3. We hypothesized this policy change would increase the likelihood to transplant marginal quality livers into HCC patients.
    Methods: This was a retrospective cohort study of a national transplant registry, including adult deceased donor liver transplant recipients with and without HCC from May 18, 2017, to May 18, 2019 (prepolicy) to May 19, 2019, to March 1, 2021 (postpolicy). Transplanted livers were considered of marginal quality if they met ≥1 of the following: (1) donation after circulatory death, (2) donor age ≥70, (3) macrosteatosis ≥30% and (4) donor risk index ≥95th percentile. We compared characteristics across policy periods and by HCC status.
    Results: A total of 23 164 patients were included (11 339 prepolicy and 11 825 postpolicy), 22.7% of whom received HCC exception points (prepolicy versus postpolicy: 26.1% versus 19.4%; P = 0.03). The percentage of transplanted donor livers meeting marginal quality criteria decreased for non-HCC (17.3% versus 16.0%; P < 0.001) but increased for HCC (17.7% versus 19.4%; P < 0.001) prepolicy versus postpolicy. After adjusting for recipient characteristics, HCC recipients had 28% higher odds of being transplanted with marginal quality liver independent of policy period (odds ratio: 1.28; confidence interval, 1.09-1.50; P < 0.01).
    Conclusions: The median Model for End-Stage Liver Disease at transplant in the listing region minus 3 policy limited exception points and decreased the quality of livers received by HCC patients.
    MeSH term(s) Adult ; Humans ; Carcinoma, Hepatocellular/surgery ; Carcinoma, Hepatocellular/pathology ; Liver Transplantation/adverse effects ; Liver Neoplasms/surgery ; Liver Neoplasms/pathology ; End Stage Liver Disease/diagnosis ; End Stage Liver Disease/surgery ; Retrospective Studies ; Tissue and Organ Procurement ; Living Donors ; Patient Selection ; Severity of Illness Index ; Policy ; Waiting Lists
    Language English
    Publishing date 2023-12-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000004621
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 488: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 509: Show issues

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  6. Article: The Impact of COVID on Adolescent Mental Health, Self-Harm and Suicide: How Can Primary Care Provider Respond? A Position Paper of the European Academy of Pediatrics.

    Michaud, Pierre-André / Michaud, Laurent / Mazur, Artur / Hadjipanayis, Adamos / Kapp, Carole / Ambresin, Anne-Emmanuelle

    Frontiers in pediatrics

    2022  Volume 10, Page(s) 800000

    Abstract: Adolescents aged 10 to 19 live a period of their life marked by opportunities and vulnerabilities during which the issue of mental health is of prime importance. Since several decades, and especially since the start of the COVID pandemic, mental health ... ...

    Abstract Adolescents aged 10 to 19 live a period of their life marked by opportunities and vulnerabilities during which the issue of mental health is of prime importance. Since several decades, and especially since the start of the COVID pandemic, mental health problems and disorders among adolescents have increased around the world. Depression, self-harm and suicidal behavior are common during this period of life, and pediatricians can play a pivotal role in identifying affected or vulnerable youngsters. This article describes risk factors for self-harm and suicidal behavior and reviews how primary care pediatricians and health professionals can respond to such situations. This scoping review is based on existing evidences as well as the authors clinical experience. It suggests concrete actions that can be taken to secure the life of at risk teenagers, and discusses how to organize the transfer to mental health professionals when needed.
    Language English
    Publishing date 2022-03-23
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2022.800000
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The Structure of the Relationship between Physical Activity and Psychosocial Functioning of Women and Men during the COVID-19 Epidemic in Poland.

    Mazur, Anna / Bartoń, Elżbieta

    International journal of environmental research and public health

    2022  Volume 19, Issue 19

    Abstract: Since the coronavirus disease (COVID-19) pandemic is a serious crisis in many countries around the world, it is important to conduct empirical research aimed at identifying risks and factors protecting the functioning of people affected by it. For this ... ...

    Abstract Since the coronavirus disease (COVID-19) pandemic is a serious crisis in many countries around the world, it is important to conduct empirical research aimed at identifying risks and factors protecting the functioning of people affected by it. For this reason, the goals of the present research were to determine the level of physical activity and the severity of symptoms characteristic of mental disorders, cognitive disorders and the quality of social functioning, as well as the structure of the relationship between physical activity and psychosocial functioning of 226 women and 226 men during the COVID-19 epidemic in Eastern Poland. The research was conducted using the
    MeSH term(s) COVID-19/epidemiology ; Exercise ; Female ; Humans ; Male ; Pandemics ; Poland/epidemiology ; Psychosocial Functioning
    Language English
    Publishing date 2022-09-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph191911860
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Ionic Liquid-Based Polymer Matrices for Single and Dual Drug Delivery: Impact of Structural Topology on Characteristics and In Vitro Delivery Efficiency.

    Niesyto, Katarzyna / Keihankhadiv, Shadi / Mazur, Aleksy / Mielańczyk, Anna / Neugebauer, Dorota

    International journal of molecular sciences

    2024  Volume 25, Issue 2

    Abstract: Previously reported amphiphilic linear and graft copolymers, derived from the ionic liquid [2-(methacryloyloxy)ethyl]trimethylammonium chloride (TMAMA_Cl‾), along with their conjugates obtained through modification either before or after polymerization ... ...

    Abstract Previously reported amphiphilic linear and graft copolymers, derived from the ionic liquid [2-(methacryloyloxy)ethyl]trimethylammonium chloride (TMAMA_Cl‾), along with their conjugates obtained through modification either before or after polymerization with
    MeSH term(s) Humans ; Polymers/chemistry ; Ionic Liquids ; Drug Carriers/chemistry ; Chlorides ; Drug Delivery Systems ; Micelles
    Chemical Substances Polymers ; Ionic Liquids ; Drug Carriers ; Chlorides ; Micelles
    Language English
    Publishing date 2024-01-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25021292
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: COVAX no fault compensation program for COVID-19 vaccine injuries in 92 low and middle income countries.

    Mazur, Anne / Benitez, Stefanie / Chuffart-Finsterwald, Stéphanie / La Rotta, Rafael / Hampton, Lee M

    Vaccine

    2021  Volume 39, Issue 49, Page(s) 7128–7130

    MeSH term(s) COVID-19 ; COVID-19 Vaccines ; Compensation and Redress ; Developing Countries ; Humans ; SARS-CoV-2
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2021-10-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2021.10.047
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1930: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 458: Show issues

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  10. Article ; Online: Sprachtests im Online-Experiment am Beispiel des Oldenburger Satztests

    Schlüter, Anne / Baumann, Elisabeth-Sophie / Ben Ghorbal, Fatma / Hauenschild, Nele / Kleinow, Alina / Mazur, Vanessa / Thomas, Julia / Holube, Inga

    GMS Zeitschrift für Audiologie - Audiological Acoustics

    2024  Volume 6, Page(s) 5

    Abstract: Während der COVID-19-Pandemie waren audiologische Untersuchungen im Labor nur unter sehr strengen Hygienemaßnahmen bzw. gar nicht möglich. Um dieses Hindernis zu umgehen, wurde ein Online-Experiment mit dem synthetischen Sprachmaterial des Oldenburger ... ...

    Title translation Speech tests in online experiments using the example of the Oldenburg sentence test
    Abstract Während der COVID-19-Pandemie waren audiologische Untersuchungen im Labor nur unter sehr strengen Hygienemaßnahmen bzw. gar nicht möglich. Um dieses Hindernis zu umgehen, wurde ein Online-Experiment mit dem synthetischen Sprachmaterial des Oldenburger Satztests (OLSA) implementiert. Dadurch sollte geprüft werden, ob online mit synthetischer Sprache vergleichbare Ergebnisse erzielt werden wie in einem vorhergehenden Experiment im Labor. Mithilfe der Plattform Gorilla (https://gorilla.sc/) wurde ein Online-Experiment erstellt und durch einen Link über verschiedene Kommunikationskanäle (z. B. in Social Media) weitergegeben. Aufgerufen wurde dieser Link 182 Mal, was zu 81 vollständigen Datensätzen führte. Die ermittelten Sprachverständlichkeitsschwellen von 69 Probanden sind vergleichbar mit den Ergebnissen aus der Laborsituation. Allerdings wichen die Steigungen der Diskriminationsfunktionen signifikant voneinander ab. Grundsätzlich konnte gezeigt werden, dass der synthetische OLSA auch als Online-Experiment durchführbar ist. Hürden im Vergleich zur Labormessung zeigten sich jedoch bei Rekrutierung und Motivation der Probanden.

    During the COVID-19 pandemic, audiological tests in the laboratory were only possible under very strict hygiene measures or not at all. To circumvent this obstacle, an online experiment was implemented using the synthetic speech material of the Oldenburg Sentence Test (OLSA). The aim was to test whether comparable results could be achieved online with synthetic speech as used in a previous experiment in the laboratory. With the help of the platform Gorilla (https://gorilla.sc/), an online experiment was created and shared through a link via various communication channels (e.g., in social media). This link was accessed 182 times, resulting in 81 complete data sets. The speech-recognition thresholds established for 69 participants were comparable to the results from the laboratory situation. However, the slopes of the discrimination functions differed significantly. In principle, it was shown that the synthetic OLSA is also feasible as an online experiment. Compared to the laboratory measurement, greater hurdles were encountered in the recruitment and motivation of the test participants.
    Keywords Medizin, Gesundheit ; OLSA ; online experiment ; SRT ; synthetic speech ; OLSA ; Online-Experiment ; SRT ; synthetische Sprache
    Publishing date 2024-04-16
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Article ; Online
    ISSN 2628-9083
    ISSN (online) 2628-9083
    DOI 10.3205/zaud000040
    Database German Medical Science

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