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  1. Article ; Online: Temporal Trends in Mortality of Critically Ill Patients with Sepsis in the United Kingdom, 1988-2019.

    Prescott, Hallie C / Harrison, David A / Rowan, Kathryn M / Shankar-Hari, Manu / Wunsch, Hannah

    American journal of respiratory and critical care medicine

    2024  Volume 209, Issue 5, Page(s) 507–516

    Abstract: Rationale: ...

    Abstract Rationale:
    MeSH term(s) Humans ; Male ; Aged ; Female ; Retrospective Studies ; Critical Illness ; Sepsis ; United Kingdom/epidemiology ; Intensive Care Units
    Language English
    Publishing date 2024-01-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202309-1636OC
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Asthma in Adults.

    Rabin, Alexander S / Junck, Larry / Shankar, Hari M

    The New England journal of medicine

    2023  Volume 389, Issue 22, Page(s) 2111

    MeSH term(s) Adult ; Humans ; Asthma
    Language English
    Publishing date 2023-12-04
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2312345
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Ex Vivo Lung Perfusion Models to Explore the Pathobiology of ARDS

    Abdalla, A. / Dhaliwal, K. / Shankar-Hari, M.

    Annual update in intensive care and emergency medicine

    2023  Volume -, Issue -, Page(s) 111

    Language English
    Document type Article
    ZDB-ID 2600427-6
    ISSN 2191-5709
    Database Current Contents Medicine

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  4. Article: Ex Vivo Lung Perfusion Models to Explore the Pathobiology of ARDS

    Abdalla, A. / Dhaliwal, K. / Shankar-Hari, M.

    Annual update in intensive care and emergency medicine

    2023  Volume -, Issue -, Page(s) 111

    Language English
    Document type Article
    ZDB-ID 2600427-6
    ISSN 2191-5709
    Database Current Contents Medicine

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  5. Article ; Online: The REMDACTA trial: do interleukin receptor antagonists provide additional benefit in COVID-19?

    Tatham, Kate C / Shankar-Hari, Manu / Arabi, Yaseen M

    Intensive care medicine

    2021  Volume 47, Issue 11, Page(s) 1315–1318

    MeSH term(s) Antibodies, Monoclonal, Humanized ; COVID-19 ; Humans ; Receptors, Interleukin ; Respiration, Artificial ; SARS-CoV-2
    Chemical Substances Antibodies, Monoclonal, Humanized ; Receptors, Interleukin
    Language English
    Publishing date 2021-10-07
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-021-06540-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: How could we enhance translation of sepsis immunology to inform immunomodulation trials in sepsis?

    Shankar-Hari, M

    Critical care (London, England)

    2017  Volume 21, Issue 1, Page(s) 125

    Abstract: Sepsis results in complex alterations to the immune system. Our understanding of how these alterations in immune responses could help characterize extreme immune phenotypes, identify biomarkers with the ability to stratify patients for therapeutic ... ...

    Abstract Sepsis results in complex alterations to the immune system. Our understanding of how these alterations in immune responses could help characterize extreme immune phenotypes, identify biomarkers with the ability to stratify patients for therapeutic interventions, surrogates in the causal pathway of clinical end-points, and treatable traits are still rudimentary. A methodologically rigorous, consensus-based approach should enrich sepsis immune subpopulations to increase the probability of successful trials.
    MeSH term(s) Biomarkers/analysis ; Humans ; Immunomodulation ; Inflammation/immunology ; Sepsis/immunology ; Sepsis/mortality ; Sepsis/therapy
    Chemical Substances Biomarkers
    Language English
    Publishing date 2017-05-26
    Publishing country England
    Document type Editorial
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-017-1715-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Delirium in COVID-19: can we make the unknowns knowns?

    Wilcox, M Elizabeth / Shankar-Hari, Manu / McAuley, Daniel F

    Intensive care medicine

    2021  Volume 47, Issue 10, Page(s) 1144–1147

    MeSH term(s) COVID-19 ; Delirium/diagnosis ; Delirium/etiology ; Humans ; SARS-CoV-2
    Language English
    Publishing date 2021-06-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-021-06467-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Paediatric Inflammatory Multisystem Syndrome Temporally-Associated with SARS-CoV-2 Infection: An Overview.

    Carter, Michael J / Shankar-Hari, Manu / Tibby, Shane M

    Intensive care medicine

    2020  Volume 47, Issue 1, Page(s) 90–93

    MeSH term(s) Adolescent ; COVID-19/complications ; COVID-19/diagnosis ; COVID-19/etiology ; COVID-19/therapy ; Child ; Child, Preschool ; Diagnosis, Differential ; Female ; Humans ; Infant ; Male ; SARS-CoV-2 ; Systemic Inflammatory Response Syndrome/diagnosis ; Systemic Inflammatory Response Syndrome/etiology ; Systemic Inflammatory Response Syndrome/therapy ; Young Adult
    Keywords covid19
    Language English
    Publishing date 2020-10-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-020-06273-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Update on Climate Change: Its Impact on Respiratory Health at Work, Home, and at Play.

    Shankar, Hari M / Rice, Mary B

    Clinics in chest medicine

    2020  Volume 41, Issue 4, Page(s) 753–761

    Abstract: Climate change is a crisis of vast proportions that has serious implications for pulmonary health. Increasing global temperatures influence respiratory health through extreme weather events, wildfires, prolonged allergy seasons, and worsening air ... ...

    Abstract Climate change is a crisis of vast proportions that has serious implications for pulmonary health. Increasing global temperatures influence respiratory health through extreme weather events, wildfires, prolonged allergy seasons, and worsening air pollution. Children, elderly patients, and patients with underlying lung disease are at elevated risk of complications from these effects of climate change. This paper summarizes the myriad ways in which climate change affects the respiratory health of patients at home and in outdoor environments and outlines measures for patients to protect themselves.
    MeSH term(s) Air Pollution/adverse effects ; Climate Change/statistics & numerical data ; Humans ; Lung Diseases/etiology
    Language English
    Publishing date 2020-11-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 447455-7
    ISSN 1557-8216 ; 0272-5231
    ISSN (online) 1557-8216
    ISSN 0272-5231
    DOI 10.1016/j.ccm.2020.08.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Acute respiratory distress syndrome (ARDS) phenotyping.

    Shankar-Hari, M / Fan, E / Ferguson, N D

    Intensive care medicine

    2018  Volume 45, Issue 4, Page(s) 516–519

    MeSH term(s) Humans ; Phenotype ; Respiratory Distress Syndrome/genetics
    Language English
    Publishing date 2018-12-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-018-5480-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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