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  1. Article ; Online: mSphere of Influence: The discovery of a missing link in bacterial cell envelope biogenesis.

    Harrison, Gregory A

    mSphere

    2024  Volume 9, Issue 2, Page(s) e0063123

    Abstract: Gregory Harrison is a bacteriologist researching essential pathways in bacteria as potential ...

    Abstract Gregory Harrison is a bacteriologist researching essential pathways in bacteria as potential therapeutic targets. In this mSphere of Influence article, he reflects on a series of studies that employ complementary genetic approaches to define the crucial role of AsmA-family proteins in transporting phospholipids between the inner and outer membranes of Gram-negative bacteria. The authors of these three studies identify this family of lipid transporters through the means of bacterial genetics, answering a long-standing question in bacterial physiology, and serving as a reminder that a well-designed genetic strategy can go a long way in uncovering new biology.
    MeSH term(s) Biological Transport ; Membrane Transport Proteins/genetics ; Membrane Transport Proteins/metabolism ; Gram-Negative Bacteria/genetics
    Chemical Substances Membrane Transport Proteins
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Journal Article
    ISSN 2379-5042
    ISSN (online) 2379-5042
    DOI 10.1128/msphere.00631-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Thesis: Grace and human freedom according to St. Gregory of Nyssa

    Harrison, Verna E. F

    (Studies in the Bible and early Christianity ; 30)

    1992  

    Author's details Verna E. F. Harrison
    Series title Studies in the Bible and early Christianity ; 30
    Keywords Free will and determinism ; Grace (Theology)
    Language Undetermined
    Size II, 286 S, 24 cm
    Publisher Edwin Mellen Press
    Publishing place Lewiston, NY u.a.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Zugl.: Berkeley, Univ., Diss. : 1986
    Note Bibliogr. S. 261-272. - Includes index ; Originally presented as author's thesis (doctoral)--Graduate Theological Union, Berkeley, 1986
    ISBN 0773495428 ; 9780773495425
    Database Former special subject collection: coastal and deep sea fishing

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  3. Article ; Online: Perioperative Management of Glucose-lowering Drugs: Comment.

    Gregory, Stephen Harrison

    Anesthesiology

    2021  Volume 134, Issue 2, Page(s) 349

    MeSH term(s) Blood Glucose ; Diabetes Mellitus, Type 2 ; Glucose ; Humans ; Hypoglycemic Agents ; Pharmaceutical Preparations
    Chemical Substances Blood Glucose ; Hypoglycemic Agents ; Pharmaceutical Preparations ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2021-01-08
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 269-0
    ISSN 1528-1175 ; 0003-3022
    ISSN (online) 1528-1175
    ISSN 0003-3022
    DOI 10.1097/ALN.0000000000003625
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 199: Show issues

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  4. Article ; Online: COVID-19; addressing our reality and maintaining our resilience.

    Harrison, Gregory

    The British journal of surgery

    2020  Volume 107, Issue 10, Page(s) e446

    MeSH term(s) Adaptation, Psychological ; COVID-19/epidemiology ; COVID-19/psychology ; Humans ; Medical Staff, Hospital/psychology ; Pandemics ; Resilience, Psychological ; SARS-CoV-2 ; Stress, Psychological ; United Kingdom/epidemiology
    Keywords covid19
    Language English
    Publishing date 2020-08-04
    Publishing country England
    Document type Letter
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1002/bjs.11906
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: COVID-19; addressing our reality and maintaining our resilience ; COVID-19; addressing our reality and maintaining our resilience

    Harrison, Gregory

    British Journal of Surgery ; ISSN 0007-1323

    2020  

    Keywords Surgery ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1002/bjs.11906
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: The impact of frailty on the management of atrial fibrillation.

    Harrison, Stephanie L / Johnsen, Søren P / Lip, Gregory Y H

    Aging

    2023  Volume 15, Issue 14, Page(s) 6622–6624

    MeSH term(s) Humans ; Aged ; Atrial Fibrillation/drug therapy ; Frailty ; Frail Elderly
    Language English
    Publishing date 2023-07-19
    Publishing country United States
    Document type Editorial
    ISSN 1945-4589
    ISSN (online) 1945-4589
    DOI 10.18632/aging.204918
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Lipids and atrial fibrillation: New insights into a paradox.

    Sagris, Dimitrios / Harrison, Stephanie L / Lip, Gregory Y H

    PLoS medicine

    2022  Volume 19, Issue 8, Page(s) e1004067

    Abstract: In this Perspective, Dimitrios Sagris, Stephanie Harrison, and Gregory Lip discuss new evidence ...

    Abstract In this Perspective, Dimitrios Sagris, Stephanie Harrison, and Gregory Lip discuss new evidence concerning the paradoxical relationship between circulating lipids and atrial fibrillation.
    MeSH term(s) Atrial Fibrillation/etiology ; Humans ; Lipids
    Chemical Substances Lipids
    Language English
    Publishing date 2022-08-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2185925-5
    ISSN 1549-1676 ; 1549-1277
    ISSN (online) 1549-1676
    ISSN 1549-1277
    DOI 10.1371/journal.pmed.1004067
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: AI in the Loop: functionalizing fold performance disagreement to monitor automated medical image segmentation workflows.

    Gottlich, Harrison C / Korfiatis, Panagiotis / Gregory, Adriana V / Kline, Timothy L

    Frontiers in radiology

    2023  Volume 3, Page(s) 1223294

    Abstract: Introduction: Methods that automatically flag poor performing predictions are drastically needed to safely implement machine learning workflows into clinical practice as well as to identify difficult cases during model training.: Methods: ... ...

    Abstract Introduction: Methods that automatically flag poor performing predictions are drastically needed to safely implement machine learning workflows into clinical practice as well as to identify difficult cases during model training.
    Methods: Disagreement between the fivefold cross-validation sub-models was quantified using dice scores between folds and summarized as a surrogate for model confidence. The summarized Interfold Dices were compared with thresholds informed by human interobserver values to determine whether final ensemble model performance should be manually reviewed.
    Results: The method on all tasks efficiently flagged poor segmented images without consulting a reference standard. Using the median Interfold Dice for comparison, substantial dice score improvements after excluding flagged images was noted for the in-domain CT (0.85 ± 0.20 to 0.91 ± 0.08, 8/50 images flagged) and MR (0.76 ± 0.27 to 0.85 ± 0.09, 8/50 images flagged). Most impressively, there were dramatic dice score improvements in the simulated out-of-distribution task where the model was trained on a radical nephrectomy dataset with different contrast phases predicting a partial nephrectomy all cortico-medullary phase dataset (0.67 ± 0.36 to 0.89 ± 0.10, 122/300 images flagged).
    Discussion: Comparing interfold sub-model disagreement against human interobserver values is an effective and efficient way to assess automated predictions when a reference standard is not available. This functionality provides a necessary safeguard to patient care important to safely implement automated medical image segmentation workflows.
    Language English
    Publishing date 2023-09-15
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2673-8740
    ISSN (online) 2673-8740
    DOI 10.3389/fradi.2023.1223294
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Gait and neuromuscular dynamics during level and uphill walking carrying military loads.

    Walsh, Gregory S / Harrison, Isabel

    European journal of sport science

    2021  Volume 22, Issue 9, Page(s) 1364–1373

    Abstract: The neuromuscular system responds to perturbation and increasing locomotor task difficulty by altering the stability of neuromuscular output signals. The purpose of this study was to determine the effects of two different military load carriage systems ... ...

    Abstract The neuromuscular system responds to perturbation and increasing locomotor task difficulty by altering the stability of neuromuscular output signals. The purpose of this study was to determine the effects of two different military load carriage systems on the dynamic stability of gait and muscle activation signals. 14 army office cadets (20 ± 1 years) performed 4-minute treadmill walking trials on level (0%) and uphill (10%) gradients while unloaded, and with 11 kg backpack and 11 kg webbing loads while the activity of 6 leg and trunk muscles and the motion of the centre of mass (COM) were recorded. Loaded and uphill walking decreased stability and increased magnitude of muscle activations compared to loaded and level gradient walking. Backpack loads increased the medio-lateral stability of COM and uphill walking decreased stability of vertical COM motion and increased stride time variability. However, there was no difference between the two load carriage systems for any variable. The reduced stability of muscle activations in loaded and uphill conditions indicates an impaired ability of the neuromuscular control systems to accommodate perturbations in these conditions which may have implications on the operational performance of military personnel. However, improved medio-lateral stability in backpack conditions may indicate that participants were able to compensate for the loads used in this study, despite the decreased vertical stability and increased stride time variability evident in uphill walking. This study did not find differences between load carriage systems however, specific load carriage system effects may be elicited by greater load carriage masses.
    MeSH term(s) Biomechanical Phenomena ; Gait/physiology ; Humans ; Military Personnel ; Muscle, Skeletal ; Walking/physiology ; Weight-Bearing/physiology
    Language English
    Publishing date 2021-07-25
    Publishing country England
    Document type Journal Article
    ISSN 1536-7290
    ISSN (online) 1536-7290
    DOI 10.1080/17461391.2021.1953154
    Database MEDical Literature Analysis and Retrieval System OnLINE

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