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  1. Article ; Online: Out-of-Hospital Intubation Trends Through the Coronavirus Disease 2019 Pandemic.

    Huebinger, Ryan / Chan, Hei Kit / Mann, N Clay / Fisher, Benjamin / Karfunkle, Benjamin / Bobrow, Bentley

    Annals of emergency medicine

    2023  Volume 82, Issue 6, Page(s) 763–765

    MeSH term(s) Humans ; COVID-19 ; Pandemics ; SARS-CoV-2 ; Intubation, Intratracheal ; Hospitals
    Language English
    Publishing date 2023-08-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603080-4
    ISSN 1097-6760 ; 0196-0644
    ISSN (online) 1097-6760
    ISSN 0196-0644
    DOI 10.1016/j.annemergmed.2023.07.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: COVID-19 Acute Respiratory Distress Syndrome and Pulmonary Embolism: A Case Report of Nebulized Nitroglycerin and Systemic Thrombolysis For Right Ventricular Failure.

    Karfunkle, Benjamin / Gill, Joseph / Shirey, Stephanie / Gordon, Richard

    The Journal of emergency medicine

    2021  Volume 61, Issue 5, Page(s) e103–e107

    Abstract: Background: Acute respiratory compromise caused by complications of COVID-19, such as acute respiratory distress syndrome (ARDS) or thromboembolic disease, is a complex syndrome with unique challenges in treatment. Management often requires time and ... ...

    Abstract Background: Acute respiratory compromise caused by complications of COVID-19, such as acute respiratory distress syndrome (ARDS) or thromboembolic disease, is a complex syndrome with unique challenges in treatment. Management often requires time and intensive care through a multiprofessional, multispecialty approach. Initial management is particularly challenging within the limited-resource environment of the emergency department (ED). The emergency physician's toolbox of treatments with reasonably rapid onset remains limited to respiratory support, prone positioning, steroids, and anticoagulation.
    Case report: We present a case of a patient with COVID-19 complicated by ARDS and bilateral pulmonary emboli with severe right ventricular dysfunction and systemic hypotension treated with nebulized nitroglycerin and systemic thrombolytic therapy in the ED. Serial evaluation of right ventricular function using point of care ultrasound over the next 2 h showed improvement of function with both agents as well as improvement in the patient's respiratory rate and work of breathing. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: This case describes a novel use of a widely available medication for patients with COVID-19-induced right ventricular dysfunction. Nebulized nitroglycerin may be an option to improve right ventricular function when other inhaled pulmonary vasodilators are not available in the initial ED setting. © 2021 Elsevier Inc.
    MeSH term(s) COVID-19 ; Humans ; Nitroglycerin/therapeutic use ; Pulmonary Embolism/complications ; Pulmonary Embolism/drug therapy ; Respiratory Distress Syndrome/drug therapy ; SARS-CoV-2 ; Thrombolytic Therapy ; Ventricular Dysfunction, Right/drug therapy ; Ventricular Dysfunction, Right/etiology
    Chemical Substances Nitroglycerin (G59M7S0WS3)
    Language English
    Publishing date 2021-07-09
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 605559-x
    ISSN 0736-4679
    ISSN 0736-4679
    DOI 10.1016/j.jemermed.2021.07.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Prehospital Ultrasound: Nationwide Incidence from the NEMSIS Database.

    Karfunkle, Benjamin / Chan, Hei Kit / Fisher, Benjamin / Gill, Joseph / Bakunas, Carrie / Gordon, Richard / Miller, Sara / Huebinger, Ryan

    Prehospital emergency care

    2023  Volume 28, Issue 3, Page(s) 515–530

    Abstract: Objective: We sought to describe prehospital ultrasound (PHUS) use and trends in PHUS utilization over time using a national database.: Methods: Using the 2018 - 2021 National Emergency Medical Services Information System databases, we identified ... ...

    Abstract Objective: We sought to describe prehospital ultrasound (PHUS) use and trends in PHUS utilization over time using a national database.
    Methods: Using the 2018 - 2021 National Emergency Medical Services Information System databases, we identified those EMS activations where PHUS was performed. We evaluated the association between year and number of PHUS exams performed using univariable and multivariable regression analysis. Analysis was performed on the overall group and various subgroups.
    Results: In total, there were 148,709,000 EMS activations by 13,899 agencies over the 4 years. Of these, 3,291 unique activations (0.002%) involved PHUS, performed by 71 EMS agencies (0.5%). The annual rate of ultrasound evaluations per 1 million EMS activations significantly increased over the study period: 5.2 in 2018, 14.8 in 2019, 18.6 in 2020, and 38.9 in 2021 (
    Conclusion: Prehospital ultrasound use in the United States increased significantly over the study period, but remains exceedingly rare. The performance of PHUS was recorded throughout the United States, with paramedics performing the majority of PHUS studies included in this database.
    MeSH term(s) Humans ; United States/epidemiology ; Emergency Medical Services ; Incidence ; Ultrasonography ; Databases, Factual ; Logistic Models
    Language English
    Publishing date 2023-08-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 1461751-1
    ISSN 1545-0066 ; 1090-3127
    ISSN (online) 1545-0066
    ISSN 1090-3127
    DOI 10.1080/10903127.2023.2239353
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: B-lines beyond the thoracic cavity - ultrasound identification of intercostal pulmonary hernia.

    Gordon, Richard / Karfunkle, Benjamin / Smith, Hannah / Larimore, Katheryn / Turgiss, Krystal / Najeemuddin, Syed

    Journal of clinical ultrasound : JCU

    2021  Volume 50, Issue 1, Page(s) 101–105

    Abstract: Intercostal pulmonary hernia is a rare condition that may present to the emergency department spontaneously, following blunt trauma or as a complication of thoracic surgery. With the evolution of minimally invasive thoracic surgery pulmonary hernia may ... ...

    Abstract Intercostal pulmonary hernia is a rare condition that may present to the emergency department spontaneously, following blunt trauma or as a complication of thoracic surgery. With the evolution of minimally invasive thoracic surgery pulmonary hernia may become more common. In this case of postoperative chest pain, incisional swelling, and shortness of breath, we present the ultrasound characteristics of a postoperative intercostal pulmonary hernia and its resemblance to subcutaneous emphysema.
    MeSH term(s) Hernia/diagnostic imaging ; Humans ; Lung ; Lung Diseases ; Thoracic Cavity ; Wounds, Nonpenetrating/complications ; Wounds, Nonpenetrating/diagnostic imaging
    Language English
    Publishing date 2021-07-12
    Publishing country United States
    Document type Case Reports
    ZDB-ID 189393-2
    ISSN 1097-0096 ; 0091-2751
    ISSN (online) 1097-0096
    ISSN 0091-2751
    DOI 10.1002/jcu.23035
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  5. Article: A Multicenter, Prospective Study Comparing Subxiphoid and Parasternal Views During Brief Echocardiography: Effect on Image Quality, Acquisition Time, and Visualized Anatomy.

    Gaspari, Romolo J / Gleeson, Timothy / Alerhand, Stephen / Caputo, William / Damewood, Sara / Dicroce, Christopher / Dwyer, Kristin / Gibbons, Ryan / Greenstein, Joshua / Harvey, Justin / Hill, Michael / Hoffmann, Beatrice / Jordan, Mary Kate / Karfunkle, Benjamin / Kropf, Charles / Lindsay, Robert / Luo, Shawn / Lusiak, Monika / Nalbandian, Ari /
    Naraghi, Leily / Nelson, Bret / Nickels, L Connor / Nolting, Laura / Nordberg, Alexandra / Panicker, Ashley / Pare, Joseph / Peach, Mandy / Pinto, Dorcas / Graham, Powell / Rose, Gabe / Russell, Frances / Schafer, Jesse / Scheatzle, Mark / Schnittke, Nikolai / Shpilko, Marina / Soucy, Zachary / Stowell, Jeffrey R / Vryhof, Daniel / Gottlieb, Michael

    The Journal of emergency medicine

    2022  Volume 62, Issue 5, Page(s) 648–656

    Abstract: Background: Recent literature has suggested echocardiography (echo) may prolong pauses in chest compressions during cardiac arrest.: Objectves: We sought to determine the impact of the sonographic approach (subxiphoid [SX] vs. parasternal long [PSL]) ...

    Abstract Background: Recent literature has suggested echocardiography (echo) may prolong pauses in chest compressions during cardiac arrest.
    Objectves: We sought to determine the impact of the sonographic approach (subxiphoid [SX] vs. parasternal long [PSL]) on time to image completion, image quality, and visualization of cardiac anatomy during echo, as performed during Advanced Cardiac Life Support.
    Methods: This was a multicenter, randomized controlled trial conducted at 29 emergency departments (EDs) assessing the time to image acquisition and image quality between SX and PSL views for echo. Patients were enrolled in the ED and imaged in a simulated cardiac arrest scenario. Clinicians experienced in echo performed both SX and PSL views, first view in random order. Image quality and time to image acquisition were recorded. Echos were evaluated for identification of cardiac landmarks. Data are presented as percentages or medians with interquartile ranges (IQRs).
    Results: We obtained 6247 echo images, comprising 3124 SX views and 3123 PSL. Overall time to image acquisition was 9.0 s (IQR 6.7-14.1 s). Image acquisition was shorter using PSL (8.8 s, IQR 6.5-13.5 s) compared with SX (9.3 s, IQR 6.7-15.0 s). The image quality was better with the PSL view (3.86 vs. 3.54; p < 0.0001), twice as many SX images scoring in the worst quality category compared with PSL (8.6% vs. 3.7%). Imaging of the pericardium, cardiac chambers, and other anatomic landmarks was superior with PSL imaging.
    Conclusions: Echo was performed in < 10 s in > 50% of patients using either imaging technique. Imaging using PSL demonstrated improved image quality and improved identification of cardiac landmarks.
    MeSH term(s) Advanced Cardiac Life Support ; Echocardiography/methods ; Heart Arrest ; Humans ; Prospective Studies ; Ultrasonography
    Language English
    Publishing date 2022-01-20
    Publishing country United States
    Document type Journal Article ; Multicenter Study ; Randomized Controlled Trial
    ZDB-ID 605559-x
    ISSN 0736-4679
    ISSN 0736-4679
    DOI 10.1016/j.jemermed.2021.10.032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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