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  1. Article ; Online: Response by Tsao and Manning to Letter Regarding Article, "COVID-19-Associated Stress (Takotsubo) Cardiomyopathy".

    Tsao, Connie W / Manning, Warren J

    Circulation. Cardiovascular imaging

    2020  Volume 13, Issue 10, Page(s) e011614

    MeSH term(s) Betacoronavirus ; COVID-19 ; Cardiomyopathies ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Takotsubo Cardiomyopathy/epidemiology
    Keywords covid19
    Language English
    Publishing date 2020-09-23
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2435045-X
    ISSN 1942-0080 ; 1941-9651
    ISSN (online) 1942-0080
    ISSN 1941-9651
    DOI 10.1161/CIRCIMAGING.120.011614
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6743: Show issues Location:
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  2. Article: Aortic Stiffness: Epidemiology, Risk Factors, and Relevant Biomarkers.

    Angoff, Rebecca / Mosarla, Ramya C / Tsao, Connie W

    Frontiers in cardiovascular medicine

    2021  Volume 8, Page(s) 709396

    Abstract: Aortic stiffness (AoS) is a maladaptive response to hemodynamic stress and both modifiable and non-modifiable risk factors, and elevated AoS increases afterload for the heart. AoS is a non-invasive marker of cardiovascular health and metabolic ... ...

    Abstract Aortic stiffness (AoS) is a maladaptive response to hemodynamic stress and both modifiable and non-modifiable risk factors, and elevated AoS increases afterload for the heart. AoS is a non-invasive marker of cardiovascular health and metabolic dysfunction. Implementing AoS as a diagnostic tool is challenging as it increases with age and varies amongst races. AoS is associated with lifestyle factors such as alcohol and smoking, as well as hypertension and comorbid conditions including metabolic syndrome and its components. Multiple studies have investigated various biomarkers associated with increased AoS, and this area is of particular interest given that these markers can highlight pathophysiologic pathways and specific therapeutic targets in the future. These biomarkers include those involved in the inflammatory cascade, anti-aging genes, and the renin-angiotensin aldosterone system. In the future, targeting AoS rather than blood pressure itself may be the key to improving vascular health and outcomes. In this review, we will discuss the current understanding of AoS, measurement of AoS and the challenges in interpretation, associated biomarkers, and possible therapeutic avenues for modulation of AoS.
    Language English
    Publishing date 2021-11-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2021.709396
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Impact of Redefinition of Normal Limits for Echocardiographic Left Ventricular Ejection Fraction on All-Cause Mortality.

    Strom, Jordan B / Markson, Lawrence J / Tsao, Connie W / Manning, Warren J

    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography

    2021  Volume 34, Issue 7, Page(s) 802–803

    MeSH term(s) Echocardiography ; Heart Ventricles/diagnostic imaging ; Humans ; Stroke Volume ; Ventricular Function, Left
    Language English
    Publishing date 2021-03-04
    Publishing country United States
    Document type Letter ; Research Support, N.I.H., Extramural
    ZDB-ID 1035622-8
    ISSN 1097-6795 ; 0894-7317
    ISSN (online) 1097-6795
    ISSN 0894-7317
    DOI 10.1016/j.echo.2021.02.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Response by Tsao and Manning to Letter Regarding Article, “COVID-19-Associated Stress (Takotsubo) Cardiomyopathy”

    Tsao, Connie W. / Manning, Warren J.

    Circulation: Cardiovascular Imaging

    2020  Volume 13, Issue 10

    Keywords Radiology Nuclear Medicine and imaging ; Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Ovid Technologies (Wolters Kluwer Health)
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2435045-X
    ISSN 1942-0080 ; 1941-9651
    ISSN (online) 1942-0080
    ISSN 1941-9651
    DOI 10.1161/circimaging.120.011614
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Zs.A 6743: Show issues Location:
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  5. Article ; Online: Reply: Size Matters? Seeking High-Risk Populations Among "Normal" Individuals.

    Tsao, Connie W / Vasan, Ramachandran S

    JACC. Heart failure

    2016  Volume 4, Issue 10, Page(s) 828–829

    MeSH term(s) Heart Failure ; Humans ; Risk Factors
    Language English
    Publishing date 2016
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2016.06.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: COVID-19-Associated Stress (Takotsubo) Cardiomyopathy.

    Tsao, Connie W / Strom, Jordan B / Chang, James D / Manning, Warren J

    Circulation. Cardiovascular imaging

    2020  Volume 13, Issue 7, Page(s) e011222

    MeSH term(s) Betacoronavirus/pathogenicity ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/therapy ; Coronavirus Infections/virology ; Female ; Host Microbial Interactions ; Humans ; Middle Aged ; Myocarditis/diagnosis ; Myocarditis/physiopathology ; Myocarditis/therapy ; Myocarditis/virology ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; Pneumonia, Viral/virology ; Risk Factors ; SARS-CoV-2 ; Takotsubo Cardiomyopathy/diagnosis ; Takotsubo Cardiomyopathy/physiopathology ; Takotsubo Cardiomyopathy/therapy ; Takotsubo Cardiomyopathy/virology ; Treatment Outcome ; Ventricular Function, Left
    Keywords covid19
    Language English
    Publishing date 2020-07-15
    Publishing country United States
    Document type Case Reports ; Research Support, N.I.H., Extramural ; Video-Audio Media
    ZDB-ID 2435045-X
    ISSN 1942-0080 ; 1941-9651
    ISSN (online) 1942-0080
    ISSN 1941-9651
    DOI 10.1161/CIRCIMAGING.120.011222
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6743: Show issues Location:
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  7. Article ; Online: Framingham Heart Study: JACC Focus Seminar, 1/8.

    Andersson, Charlotte / Nayor, Matthew / Tsao, Connie W / Levy, Daniel / Vasan, Ramachandran S

    Journal of the American College of Cardiology

    2021  Volume 77, Issue 21, Page(s) 2680–2692

    Abstract: The Framingham Heart Study is the longest-running cardiovascular epidemiological study, starting in 1948. This paper gives an overview of the various cohorts, collected data, and most important research findings to date. In brief, the Framingham Heart ... ...

    Abstract The Framingham Heart Study is the longest-running cardiovascular epidemiological study, starting in 1948. This paper gives an overview of the various cohorts, collected data, and most important research findings to date. In brief, the Framingham Heart Study, funded by the National Institutes of Health and managed by Boston University, spans 3 generations of well phenotyped White persons and 2 cohorts comprised of racial and ethnic minority groups. These cohorts are densely phenotyped, with extensive longitudinal follow-up, and they continue to provide us with important information on human cardiovascular and noncardiovascular physiology over the lifespan, as well as to identify major risk factors for cardiovascular disease. This paper also summarizes some of the more recent progress in molecular epidemiology and discusses the future of the study.
    MeSH term(s) Cardiology/history ; Coronary Disease/epidemiology ; History, 20th Century ; History, 21st Century ; Humans ; Longitudinal Studies ; Massachusetts/epidemiology
    Language English
    Publishing date 2021-05-26
    Publishing country United States
    Document type Historical Article ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, N.I.H., Intramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2021.01.059
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Relations of Metabolic Health and Obesity to Brain Aging in Young to Middle-Aged Adults.

    Angoff, Rebecca / Himali, Jayandra J / Maillard, Pauline / Aparicio, Hugo J / Vasan, Ramachandran S / Seshadri, Sudha / Beiser, Alexa S / Tsao, Connie W

    Journal of the American Heart Association

    2022  Volume 11, Issue 6, Page(s) e022107

    Abstract: Background We aimed to evaluate the association between metabolic health and obesity and brain health measured via magnetic resonance imaging and neurocognitive testing in community dwelling adults. Methods and Results Framingham Heart Study Third ... ...

    Abstract Background We aimed to evaluate the association between metabolic health and obesity and brain health measured via magnetic resonance imaging and neurocognitive testing in community dwelling adults. Methods and Results Framingham Heart Study Third Generation Cohort members (n=2170, 46±9 years of age, 54% women) without prevalent diabetes, stroke, dementia, or other neurologic conditions were grouped by metabolic unhealthiness (≥2 criteria for metabolic syndrome) and obesity (body mass index ≥30 kg/m
    MeSH term(s) Adult ; Aging ; Body Mass Index ; Brain/metabolism ; Cross-Sectional Studies ; Female ; Humans ; Male ; Metabolic Syndrome/complications ; Middle Aged ; Obesity/complications ; Obesity/epidemiology ; Obesity/metabolism
    Language English
    Publishing date 2022-03-01
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.121.022107
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Cardiovascular endocrinology: Growth hormone in CVD prediction--a tall order?

    Tsao, Connie W / Vasan, Ramachandran S

    Nature reviews. Endocrinology

    2015  Volume 11, Issue 1, Page(s) 11–13

    MeSH term(s) Cardiovascular Diseases/blood ; Female ; Human Growth Hormone/blood ; Humans ; Male ; Neoplasms/blood
    Chemical Substances Human Growth Hormone (12629-01-5)
    Language English
    Publishing date 2015-01
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 2489381-X
    ISSN 1759-5037 ; 1759-5029
    ISSN (online) 1759-5037
    ISSN 1759-5029
    DOI 10.1038/nrendo.2014.204
    Database MEDical Literature Analysis and Retrieval System OnLINE

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