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  1. Article ; Online: Recollections on the life of Professor Ewa Kossowska MD.

    Chmielik, Mieczyslaw / Chmielik, Lechoslaw P

    International journal of pediatric otorhinolaryngology

    2012  Volume 76, Issue 6, Page(s) 765–766

    MeSH term(s) Female ; History, 20th Century ; Humans ; Otolaryngology/history ; Physician's Role ; Poland
    Language English
    Publishing date 2012-07-10
    Publishing country Ireland
    Document type Biography ; Historical Article ; Journal Article
    ZDB-ID 754501-0
    ISSN 1872-8464 ; 0165-5876
    ISSN (online) 1872-8464
    ISSN 0165-5876
    DOI 10.1016/j.ijporl.2012.04.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Rak piersi

    Chmielik, Ewa

    standardy oceny morfologicznej materiału tkankowego oraz wybrane zagadnienia dotyczące karcinogenezy i biologii nowotworu

    (Polish journal of pathology ; 62,4, Suppl. 4)

    2011  

    Author's details Ewa Chmielik
    Series title Polish journal of pathology ; 62,4, Suppl. 4
    Collection
    Language Polish
    Size s50 S. : zahlr Ill.
    Edition Wersja zaktualizowana
    Publisher Termedia
    Publishing place Poznań
    Publishing country Poland
    Document type Book
    HBZ-ID HT017304776
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Pathology and Tumor Microenvironment: Past, Present, and Future.

    Chmielik, Ewa

    Pathobiology : journal of immunopathology, molecular and cellular biology

    2020  Volume 87, Issue 2, Page(s) 55–57

    MeSH term(s) Biomedical Research/trends ; Humans ; Neoplasms/drug therapy ; Neoplasms/pathology ; Tumor Microenvironment
    Language English
    Publishing date 2020-04-14
    Publishing country Switzerland
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 1022703-9
    ISSN 1423-0291 ; 1015-2008
    ISSN (online) 1423-0291
    ISSN 1015-2008
    DOI 10.1159/000507222
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Vulvar Merkel cell carcinoma combined with squamous cell carcinoma of the vulva.

    Cwynar, Marlena / Chmielik, Ewa / Cwynar, Grzegorz / Ptak, Piotr / Kowalczyk, Karolina

    Ginekologia polska

    2023  

    Language English
    Publishing date 2023-09-25
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 130894-4
    ISSN 2543-6767 ; 0017-0011
    ISSN (online) 2543-6767
    ISSN 0017-0011
    DOI 10.5603/gpl.96927
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Nowe i kontrowersyjne jednostki morfologiczne w patologii gruczołu piersiowego.

    Chmielik, Ewa

    Polish journal of pathology : official journal of the Polish Society of Pathologists

    2014  Volume 65, Issue 4 Suppl 2, Page(s) S42–52

    Title translation New and controversial morphological units in the pathology of the breast .
    MeSH term(s) Breast Neoplasms/pathology ; Carcinoma in Situ/pathology ; Carcinoma, Lobular/pathology ; Carcinoma, Papillary/pathology ; Epithelial Cells/pathology ; Female ; Humans
    Language Polish
    Publishing date 2014-12
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 1283064-1
    ISSN 1233-9687 ; 0031-3114
    ISSN 1233-9687 ; 0031-3114
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Stereotactic Radiotherapy Boost in Treatment of Persistent Periocular Sebaceous Carcinoma after Surgery.

    Polanowski, Paweł / Nasiek, Aleksandra / Grządziel, Aleksandra / Chmielik, Ewa / Pietruszka, Agnieszka / Składowski, Krzysztof / Polanowska, Katarzyna

    Biomedicines

    2023  Volume 11, Issue 6

    Abstract: Sebaceous carcinoma is a rare malignancy that should be treated with surgical resection. Nonetheless, a dynamic and aggressive course of the disease may disqualify a patient from this treatment. Applying radiotherapy with the escalation dose using a ... ...

    Abstract Sebaceous carcinoma is a rare malignancy that should be treated with surgical resection. Nonetheless, a dynamic and aggressive course of the disease may disqualify a patient from this treatment. Applying radiotherapy with the escalation dose using a stereotactic boost is worthy of consideration as a radical treatment. In this paper, we present the case study of a young patient with a tumor localized in the periocular area. The patient was treated with operation two times without a satisfactory effect. Conventional radiotherapy, 60 Gy in 30 fractions, combined with chemotherapy based on cisplatin 40 mg/m
    Language English
    Publishing date 2023-05-26
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11061538
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: The Relationship between Histological Composition and Metabolic Profile in Breast Tumors and Peritumoral Tissue Determined with

    Skorupa, Agnieszka / Ciszek, Mateusz / Turska-d'Amico, Maria / Stobiecka, Ewa / Chmielik, Ewa / Szumniak, Ryszard / d'Amico, Andrea / Boguszewicz, Łukasz / Sokół, Maria

    Cancers

    2023  Volume 15, Issue 4

    Abstract: Breast tumors constitute the complex entities composed of cancer cells and stromal components. The compositional heterogeneity should be taken into account in bulk tissue metabolomics studies. The aim of this work was to find the relation between the ... ...

    Abstract Breast tumors constitute the complex entities composed of cancer cells and stromal components. The compositional heterogeneity should be taken into account in bulk tissue metabolomics studies. The aim of this work was to find the relation between the histological content and
    Language English
    Publishing date 2023-02-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15041283
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Stereotactic Radiotherapy Boost in Treatment of Persistent Periocular Sebaceous Carcinoma after Surgery

    Paweł Polanowski / Aleksandra Nasiek / Aleksandra Grządziel / Ewa Chmielik / Agnieszka Pietruszka / Krzysztof Składowski / Katarzyna Polanowska

    Biomedicines, Vol 11, Iss 1538, p

    2023  Volume 1538

    Abstract: Sebaceous carcinoma is a rare malignancy that should be treated with surgical resection. Nonetheless, a dynamic and aggressive course of the disease may disqualify a patient from this treatment. Applying radiotherapy with the escalation dose using a ... ...

    Abstract Sebaceous carcinoma is a rare malignancy that should be treated with surgical resection. Nonetheless, a dynamic and aggressive course of the disease may disqualify a patient from this treatment. Applying radiotherapy with the escalation dose using a stereotactic boost is worthy of consideration as a radical treatment. In this paper, we present the case study of a young patient with a tumor localized in the periocular area. The patient was treated with operation two times without a satisfactory effect. Conventional radiotherapy, 60 Gy in 30 fractions, combined with chemotherapy based on cisplatin 40 mg/m 2 and the addition of a stereotactic radiosurgery boost were administered. The tolerance of this treatment was acceptable. During the 2-year follow-up, local and distant recurrences were not diagnosed. The presented case shows the usefulness of an individualized approach in the radical treatment of sebaceous carcinoma with the use of the stereotactic radiotherapy boost. This is a subsequent example of the implementation of the boost in head and neck carcinoma, which yields a positive result.
    Keywords sebaceous carcinoma ; stereotactic radiotherapy ; radiosurgery boost ; Biology (General) ; QH301-705.5
    Subject code 616
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Laryngeal chondrosarcoma treated with conventional radiotherapy - case report and review of the literature.

    Roch-Zniszczoł, Agata / Księżniak-Baran, Dorota / Chmielik, Ewa / Goleń, Maria / Amrogowicz, Natalia / Gabryś, Dorota

    Polish journal of pathology : official journal of the Polish Society of Pathologists

    2022  Volume 73, Issue 2, Page(s) 176–179

    Abstract: We report a case of a 68-year-old patient with laryngeal chondrosarcoma, whose first symptoms were hoarseness and gradually increasing dyspnoea, but there was no sign of disease in clinical examination, which postponed the diagnosis. The patient ... ...

    Abstract We report a case of a 68-year-old patient with laryngeal chondrosarcoma, whose first symptoms were hoarseness and gradually increasing dyspnoea, but there was no sign of disease in clinical examination, which postponed the diagnosis. The patient underwent complete laryngectomy and adjuvant conformal radiotherapy with a total dose of 70 Gy. The pathological assessment confirmed advanced laryngeal chondrosarcoma originating from thyroid cartilage. Imaging studies and directoscopy were performed, and they did not reveal recurrence or metastases of the disease for 6 years. Distant metastatic spread in the liver and lungs was confirmed 7 years after diagnosis, which caused hepatic insufficiency and led to death.
    MeSH term(s) Humans ; Aged ; Chondrosarcoma/radiotherapy ; Chondrosarcoma/pathology ; Laryngeal Neoplasms/radiotherapy ; Laryngeal Neoplasms/pathology ; Laryngectomy/methods ; Bone Neoplasms
    Language English
    Publishing date 2022-09-07
    Publishing country Poland
    Document type Review ; Case Reports
    ZDB-ID 1283064-1
    ISSN 1233-9687 ; 0031-3114
    ISSN 1233-9687 ; 0031-3114
    DOI 10.5114/pjp.2022.119240
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Prognostic Value of Molecular Intratumor Heterogeneity in Primary Oral Cancer and Its Lymph Node Metastases Assessed by Mass Spectrometry Imaging.

    Kurczyk, Agata / Gawin, Marta / Paul, Piotr / Chmielik, Ewa / Rutkowski, Tomasz / Pietrowska, Monika / Widłak, Piotr

    Molecules (Basel, Switzerland)

    2022  Volume 27, Issue 17

    Abstract: Different aspects of intra-tumor heterogeneity (ITH), which are associated with the development of cancer and its response to treatment, have postulated prognostic value. Here we searched for potential association between phenotypic ITH analyzed by mass ... ...

    Abstract Different aspects of intra-tumor heterogeneity (ITH), which are associated with the development of cancer and its response to treatment, have postulated prognostic value. Here we searched for potential association between phenotypic ITH analyzed by mass spectrometry imaging (MSI) and prognosis of head and neck cancer. The study involved tissue specimens resected from 77 patients with locally advanced oral squamous cell carcinoma, including 37 patients where matched samples of primary tumor and synchronous lymph node metastases were analyzed. A 3-year follow-up was available for all patients which enabled their separation into two groups: with no evidence of disease (NED,
    MeSH term(s) Carcinoma, Squamous Cell/pathology ; Head and Neck Neoplasms ; Humans ; Lymphatic Metastasis ; Mass Spectrometry ; Mouth Neoplasms/diagnostic imaging ; Mouth Neoplasms/genetics ; Mouth Neoplasms/pathology ; Prognosis ; Tumor Microenvironment
    Language English
    Publishing date 2022-08-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27175458
    Database MEDical Literature Analysis and Retrieval System OnLINE

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