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  1. Article ; Online: Blood stored for 42 days delivers oxygen as well as blood stored for 7 days.

    Dzik, Sunny

    Transfusion

    2021  Volume 61, Issue 3, Page(s) 657–659

    MeSH term(s) Blood Preservation ; Erythrocyte Transfusion ; Oxygen
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2021-03-14
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 208417-x
    ISSN 1537-2995 ; 0041-1132
    ISSN (online) 1537-2995
    ISSN 0041-1132
    DOI 10.1111/trf.16305
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  2. Article ; Online: COVID-19 Convalescent Plasma: Now Is the Time for Better Science.

    Dzik, Sunny

    Transfusion medicine reviews

    2020  Volume 34, Issue 3, Page(s) 141–144

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-23
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 639107-2
    ISSN 1532-9496 ; 0887-7963
    ISSN (online) 1532-9496
    ISSN 0887-7963
    DOI 10.1016/j.tmrv.2020.04.002
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  3. Article ; Online: Spikes in demand for hospital transfusion services.

    Dzik, 'Sunny' Walter

    Transfusion

    2021  Volume 61, Issue 3, Page(s) 722–729

    Abstract: Introduction: Spikes in the demand for blood components represent a substantial challenge to transfusion services. Simple metrics for characterizing volatility in blood components within the hospital transfusion service have not been established.: ... ...

    Abstract Introduction: Spikes in the demand for blood components represent a substantial challenge to transfusion services. Simple metrics for characterizing volatility in blood components within the hospital transfusion service have not been established.
    Methods: We measured the volatility of demand for blood services at a large academic urban general hospital over a 6-month period from July 2019 to December 2019 prior to the SARS-CoV2 pandemic.
    Results: Among 4416 consecutive hours assessed, there were 693 h (16%) with spikes in demand for blood components with a mean (sd) of 3.8 (2.7) spikes/day. Spikes in demand were frequently clustered. The median number of hours between spikes differed by shift (6 h for days; 3 h for evenings; 3 h for nights). The percentage of shift hours with demand spikes also differed (9% day; 19% evening; 18% night). During the study, 32,447 components were distributed to 19,431 patients. Of these, 11,819 components (36%) were distributed during hours of peak demand. Hours with a simultaneous spike in both component demand and patient demand occurred in 5% of hours or approximately once each day.
    Conclusion: Demand for transfusion services was highly volatile in an unpredictable fashion. We provide an approach that could be used to benchmark spikes in demand for blood services at hospitals. Consideration of the frequency, unpredictability, and magnitude of spikes in demand may be relevant for hemovigilance programs and for strategies to determine the laboratory staffing needed for good patient care.
    MeSH term(s) Blood Component Transfusion/statistics & numerical data ; Blood Safety ; Blood Transfusion/statistics & numerical data ; COVID-19/complications ; COVID-19/therapy ; Hospitals ; Humans ; Time Factors ; Volatilization ; Workforce/statistics & numerical data
    Language English
    Publishing date 2021-02-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208417-x
    ISSN 1537-2995 ; 0041-1132
    ISSN (online) 1537-2995
    ISSN 0041-1132
    DOI 10.1111/trf.16299
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  4. Article ; Online: Recommended Papers of 2022 From the TMR Editorial Board.

    Dzik, Sunny / Murphy, Michael

    Transfusion medicine reviews

    2022  Volume 37, Issue 1, Page(s) 1–6

    Language English
    Publishing date 2022-12-17
    Publishing country United States
    Document type Editorial
    ZDB-ID 639107-2
    ISSN 1532-9496 ; 0887-7963
    ISSN (online) 1532-9496
    ISSN 0887-7963
    DOI 10.1016/j.tmrv.2022.12.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Complement and Coagulation: Cross Talk Through Time.

    Dzik, Sunny

    Transfusion medicine reviews

    2019  Volume 33, Issue 4, Page(s) 199–206

    Abstract: Two complex protein defense systems-complement and coagulation-are based on amplifying enzyme cascades triggered by specific local stimuli. Excess systemic activation of either system is pathologic and is normally prevented by a family of regulatory ... ...

    Abstract Two complex protein defense systems-complement and coagulation-are based on amplifying enzyme cascades triggered by specific local stimuli. Excess systemic activation of either system is pathologic and is normally prevented by a family of regulatory proteins. The 2 systems are ancient biological processes which share a common origin that predates vertebrate evolution. Recent research has uncovered multiple opportunities for cross talk between complement and coagulation including proteins traditionally viewed as coagulation factors that activate and regulate complement, and proteins traditionally seen as part of the complement system that participate in coagulation. Ten examples of cross talk between the 2 systems are described. The mutual engagement of both systems is increasingly recognized to occur in human diseases. Three conditions-paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, and the antiphospholipid syndrome-provide examples of the importance of interactions between complement and coagulation in human biology. A better understanding of the mutual engagement of these 2 ancient defense systems is expected to result in improved diagnostics and new treatments for systemic diseases.
    MeSH term(s) Animals ; Antiphospholipid Syndrome/physiopathology ; Atypical Hemolytic Uremic Syndrome/physiopathology ; Biological Evolution ; Blood Coagulation/physiology ; Blood Coagulation Factors/physiology ; Complement Activation/physiology ; Complement System Proteins/physiology ; Hemoglobinuria, Paroxysmal/physiopathology ; Horseshoe Crabs ; Humans
    Chemical Substances Blood Coagulation Factors ; Complement System Proteins (9007-36-7)
    Language English
    Publishing date 2019-08-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 639107-2
    ISSN 1532-9496 ; 0887-7963
    ISSN (online) 1532-9496
    ISSN 0887-7963
    DOI 10.1016/j.tmrv.2019.08.004
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  6. Article ; Online: Pluribus ex uno: Allo-sensitization to an HLA "public epitope".

    Dzik, Walter Sunny / Pattanayak, Vikram

    Transfusion

    2022  Volume 62, Issue 8, Page(s) 1481–1482

    MeSH term(s) Epitopes ; HLA Antigens ; Humans
    Chemical Substances Epitopes ; HLA Antigens
    Language English
    Publishing date 2022-05-31
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 208417-x
    ISSN 1537-2995 ; 0041-1132
    ISSN (online) 1537-2995
    ISSN 0041-1132
    DOI 10.1111/trf.16937
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  8. Article ; Online: Artificial Intelligence and Scholarship in the 21st Century.

    Dzik, Sunny / Murphy, Michael / Garland, Rachel

    Transfusion medicine reviews

    2023  Volume 37, Issue 2, Page(s) 150722

    MeSH term(s) Humans ; History, 21st Century ; History, 20th Century ; Artificial Intelligence ; Fellowships and Scholarships
    Language English
    Publishing date 2023-02-24
    Publishing country United States
    Document type Historical Article ; Editorial
    ZDB-ID 639107-2
    ISSN 1532-9496 ; 0887-7963
    ISSN (online) 1532-9496
    ISSN 0887-7963
    DOI 10.1016/j.tmrv.2023.02.002
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  9. Article ; Online: COVID-19 Convalescent Plasma

    Dzik, Sunny

    Transfusion Medicine Reviews

    Now Is the Time for Better Science

    2020  Volume 34, Issue 3, Page(s) 141–144

    Keywords Clinical Biochemistry ; Hematology ; Biochemistry, medical ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 639107-2
    ISSN 1532-9496 ; 0887-7963
    ISSN (online) 1532-9496
    ISSN 0887-7963
    DOI 10.1016/j.tmrv.2020.04.002
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: James Blundell, Obstetrical Hemorrhage, and the Origins of Transfusion Medicine.

    Dzik, Sunny

    Transfusion medicine reviews

    2018  Volume 32, Issue 4, Page(s) 205–212

    Abstract: Although James Blundell is rightly acknowledged as the father of modern transfusion therapy, a review of the events surrounding the initial human-to-human transfusions in the first decades of the 19th century reveals substantial contributions by Blundell' ...

    Abstract Although James Blundell is rightly acknowledged as the father of modern transfusion therapy, a review of the events surrounding the initial human-to-human transfusions in the first decades of the 19th century reveals substantial contributions by Blundell's collaborators. Bundell's uncle John Haighton provided substantial support for animal experimentation in the growing field of physiology studies. John Leacock of Barbados provided the essential original experiments that focused the path of investigation on within-species transfusions. London instrument makers such as Laundy and Lloyd provided precision-made syringes without risk of air embolism. Fellow obstetricians Charles Waller and Edward Doubleday became ardent supporters of the new therapy and brought case referrals to Blundell's attention and care. British medical journals, such as The Lancet, provided much needed dissemination of early successes to curious medical practitioners. This 200th anniversary year of the first successful attempts at human-to-human transfusion presents an opportunity to review the failures and successes which occurred during the first days of what would ultimately become a life-saving treatment for millions worldwide.
    MeSH term(s) Animals ; Blood Transfusion/history ; Cats ; Dogs ; Equipment Design ; Hemorrhage/therapy ; History, 19th Century ; Humans ; Obstetrics/history ; Postpartum Hemorrhage/therapy ; Sheep ; Transfusion Medicine/methods
    Language English
    Publishing date 2018-08-23
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article ; Portrait ; Review
    ZDB-ID 639107-2
    ISSN 1532-9496 ; 0887-7963
    ISSN (online) 1532-9496
    ISSN 0887-7963
    DOI 10.1016/j.tmrv.2018.08.003
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