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  1. Article ; Online: Good Outcomes in Babies With In Utero Bedaquiline Exposure.

    Marais, Ben J

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2020  Volume 72, Issue 7, Page(s) 1169–1170

    MeSH term(s) Diarylquinolines/adverse effects ; Female ; Humans ; Infant ; Pregnancy ; Pregnant Women ; Rifampin ; South Africa ; Tuberculosis, Multidrug-Resistant
    Chemical Substances Diarylquinolines ; bedaquiline (78846I289Y) ; Rifampin (VJT6J7R4TR)
    Language English
    Publishing date 2020-03-03
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciaa174
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1505: Show issues Location:
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    Zs.MO 480: Show issues

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  2. Article ; Online: COVID-19 Disease Spectrum in Children: First Insights from Africa.

    Marais, Ben J

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2020  Volume 72, Issue 12, Page(s) e945–e947

    MeSH term(s) COVID-19 ; Child ; Hospitals ; Humans ; SARS-CoV-2 ; South Africa
    Keywords covid19
    Language English
    Publishing date 2020-10-29
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciaa1731
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 480: Show issues

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  3. Article ; Online: Improved Urine Lipoarabinomannan (LAM) Tests: The Answer for Child Tuberculosis Diagnosis?

    Marais, Ben J

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2020  Volume 72, Issue 9, Page(s) e289–e290

    MeSH term(s) Child ; Humans ; Lipopolysaccharides ; Tuberculosis/diagnosis ; Tuberculosis, Pulmonary
    Chemical Substances Lipopolysaccharides ; lipoarabinomannan
    Language English
    Publishing date 2020-08-05
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciaa1058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The Value of Chest Radiography in Tuberculosis Preventive Treatment Screening in Children and Adolescents.

    Marais, Ben J / Graham, Stephen M

    American journal of respiratory and critical care medicine

    2022  Volume 206, Issue 7, Page(s) 814–816

    MeSH term(s) Adolescent ; Child ; Humans ; Mass Screening ; Radiography ; Tuberculosis/diagnostic imaging ; Tuberculosis/epidemiology ; Tuberculosis/prevention & control
    Language English
    Publishing date 2022-06-10
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202205-1023ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Closing the policy-practice gap for tuberculosis preventive treatment.

    Casenghi, Martina / Furin, Jennifer / Sekadde, Moorine P / Sharma, Sangeeta / Marais, Ben J

    The Lancet. Child & adolescent health

    2024  Volume 8, Issue 5, Page(s) 315–317

    MeSH term(s) Humans ; Professional Practice Gaps ; Tuberculosis/prevention & control ; Policy
    Language English
    Publishing date 2024-03-21
    Publishing country England
    Document type Journal Article
    ISSN 2352-4650
    ISSN (online) 2352-4650
    DOI 10.1016/S2352-4642(24)00018-X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Tuberculosis in elderly Australians: a 10-year retrospective review.

    Lisson, Yasmin / Lal, Aparna / Marais, Ben J / Glynn-Robinson, Anna

    Western Pacific surveillance and response journal : WPSAR

    2024  Volume 15, Issue 1, Page(s) 1–10

    Abstract: Objective: This report describes the epidemiology of active tuberculosis (TB) in elderly Australians (≥ 65 years) with analysis of the factors associated with TB disease and successful treatment outcomes.: Methods: A retrospective study of TB cases ... ...

    Abstract Objective: This report describes the epidemiology of active tuberculosis (TB) in elderly Australians (≥ 65 years) with analysis of the factors associated with TB disease and successful treatment outcomes.
    Methods: A retrospective study of TB cases reported to the National Notifiable Diseases Surveillance System over a 10-year period from 2011 to 2020 was conducted. Cases were stratified by sex, age, risk factors, drug resistance, treatment type and outcome. Notification rates and incidence rate ratios with 95% confidence intervals were calculated and factors associated with treatment success analysed using multivariable logistic regression.
    Results: A total of 2231 TB cases among elderly people were reported over the study period, with a 10-year mean incidence rate of 6.2 per 100 000 population. The median age of cases was 75 years (range 65-100 years); most were male (65%) and born overseas (85%). Multivariable analysis found that successful treatment outcome was strongly associated with younger age, while unsuccessful treatment outcome was associated with being diagnosed within the first 2 years of arrival in Australia, ever having resided in an aged-care facility and resistance to fluoroquinolones.
    Discussion: Compared to other low-incidence settings in the Western Pacific Region, TB incidence in elderly people is low and stable in Australia, with most cases occurring among recent migrants from TB-endemic settings. Continued efforts to reduce TB importation and address migrant health, especially among elderly people, are important.
    MeSH term(s) Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Australasian People ; Australia/epidemiology ; Retrospective Studies ; Risk Factors ; Tuberculosis/drug therapy ; Tuberculosis/epidemiology
    Language English
    Publishing date 2024-01-05
    Publishing country Philippines
    Document type Journal Article
    ZDB-ID 2592503-9
    ISSN 2094-7313 ; 2094-7313
    ISSN (online) 2094-7313
    ISSN 2094-7313
    DOI 10.5365/wpsar.2024.15.1.1040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Newer Drugs for Tuberculosis Prevention and Treatment in Children.

    Marais, Ben J

    Indian journal of pediatrics

    2019  Volume 86, Issue 8, Page(s) 725–731

    Abstract: Children suffer a huge and often an unrecognized burden of tuberculosis (TB) in endemic countries like India. Better data have improved the visibility of childhood TB, but the establishment of functional TB prevention and treatment programs for children ... ...

    Abstract Children suffer a huge and often an unrecognized burden of tuberculosis (TB) in endemic countries like India. Better data have improved the visibility of childhood TB, but the establishment of functional TB prevention and treatment programs for children remains challenging. Barriers to TB prevention include: 1) non-implementation of existing guidelines, 2) perceived inability to rule out active TB with fear of creating drug resistance and 3) limited local guidance on the use of preventive therapy after close contact with drug resistant TB. Barriers to TB treatment include: 1) diagnostic challenges in resource-limited settings, 2) presentation to maternal and child health (MCH) services with poor linkage to the TB control program and 3) limited local guidance on the treatment of children with likely drug resistant TB. The authors provide an overview of newer drugs used for TB prevention and treatment in children. They discuss new options for the treatment of latent TB infection (LTBI) and new or repurposed drugs used in the treatment of children with multidrug resistant (MDR)-TB. The background information provided describes the benefits, risks and feasibility of various treatment options, which should assist treatment decisions until updated World Health Organization (WHO) guidance becomes available.
    MeSH term(s) Antitubercular Agents/therapeutic use ; Child ; Humans ; Latent Tuberculosis/drug therapy ; Tuberculosis/diagnosis ; Tuberculosis/drug therapy ; Tuberculosis/prevention & control ; Tuberculosis, Multidrug-Resistant/diagnosis ; Tuberculosis, Multidrug-Resistant/drug therapy ; Tuberculosis, Multidrug-Resistant/prevention & control
    Chemical Substances Antitubercular Agents
    Language English
    Publishing date 2019-02-01
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-018-02854-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 826: Show issues Location:
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  9. Article ; Online: Symptom-based screening of children with household tuberculosis contact.

    Marais, Ben J

    The Lancet. Respiratory medicine

    2018  Volume 6, Issue 4, Page(s) 235–237

    MeSH term(s) Child ; Family Characteristics ; Humans ; Infant ; Mycobacterium tuberculosis ; Tuberculosis ; Tuberculosis, Pulmonary
    Language English
    Publishing date 2018
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(17)30496-4
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    Zs.A 7041: Show issues Location:
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  10. Article ; Online: Preventing tuberculosis in household contacts crucial to protect children and contain epidemic spread.

    Marais, Ben J

    The Lancet. Global health

    2018  Volume 6, Issue 12, Page(s) e1260–e1261

    MeSH term(s) Child ; Epidemics ; Family Characteristics ; Humans ; Tuberculosis/epidemiology ; Tuberculosis, Multidrug-Resistant/epidemiology
    Language English
    Publishing date 2018-09-25
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2723488-5
    ISSN 2214-109X ; 2214-109X
    ISSN (online) 2214-109X
    ISSN 2214-109X
    DOI 10.1016/S2214-109X(18)30449-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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