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  1. Article ; Online: Clinical features and outcome of eight patients with Chlamydia psittaci pneumonia diagnosed by targeted next generation sequencing.

    Zhang, Yanping / Jiang, Xiangsen / Ye, Wei / Sun, Jinlin

    The clinical respiratory journal

    2023  Volume 17, Issue 9, Page(s) 915–930

    Abstract: Introduction: The clinical symptoms of Chlamydia psittaci pneumonia are still poorly understood. This study was designed to summarize the clinical features and outcome of eight C. psittaci pneumonia patients diagnosed by targeted next generation ... ...

    Abstract Introduction: The clinical symptoms of Chlamydia psittaci pneumonia are still poorly understood. This study was designed to summarize the clinical features and outcome of eight C. psittaci pneumonia patients diagnosed by targeted next generation sequencing (tNGS).
    Methods: We included eight C. psittaci pneumonia patients admitted to our hospital from January 2021 to July 2022. The tNGS was performed to the samples collected from bronchoalveolar lavage fluid of each patient. Their clinical data were analysed, including baseline features, clinical symptoms, chest radiographic findings and laboratory examinations.
    Results: The tNGS sequence number for C. psittaci was in a range of 10 to 1722. The radiographic characteristics were mainly featured by patchy consolidation shadows, ground-glass density shadows, air bronchogram and slight pleural effusion. Within 1-3 days after hospitalization, most patients showed increased neutrophil ratio, C-reactive protein and erythrocyte sedimentation rate, and decreased lymphocyte count, total protein, albumin and prealbumin. Some patients showed increased glutamic-pyruvic transaminase, glutamic-oxaloacetic transaminase and lactate dehydrogenase levels. Three critically ill patients showed increased creatine kinase, creatine kinase isoenzyme and high-sensitivity troponin T (hs-TnT) levels.
    Conclusions: A poultry or bird contact history, typical flu-like symptoms, patchy consolidation, ground-glass density shadow and air bronchogram may contribute to the diagnosis and treatment of C. psittaci pneumonia. Increase in creatine kinase, creatine kinase isoenzyme and hs-TnT may indicate a severe condition. Moxifloxacin and minocycline were effective in the management of C. psittaci pneumonia.
    MeSH term(s) Humans ; Chlamydophila psittaci/genetics ; High-Throughput Nucleotide Sequencing ; Creatine ; Isoenzymes ; Pneumonia
    Chemical Substances Creatine (MU72812GK0) ; Isoenzymes
    Language English
    Publishing date 2023-08-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2442214-9
    ISSN 1752-699X ; 1752-6981
    ISSN (online) 1752-699X
    ISSN 1752-6981
    DOI 10.1111/crj.13681
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Correlation study and clinical value analysis between cerebral microbleeds and white matter hyperintensity with high-field susceptibility-weighted imaging.

    Zhao, Xiumin / Yin, Liang / Yu, Lei / Jiang, Xiangsen / Tian, Ning / Yin, Zudong

    Medicine

    2023  Volume 102, Issue 36, Page(s) e35003

    Abstract: This study aimed to investigate the relationship between white matter hyperintensity (WMH) and cerebral microbleeds (CMBs) using susceptibility-weighted imaging (SWI) with high resolution. Additionally, it sought to analyze the clinical significance of ... ...

    Abstract This study aimed to investigate the relationship between white matter hyperintensity (WMH) and cerebral microbleeds (CMBs) using susceptibility-weighted imaging (SWI) with high resolution. Additionally, it sought to analyze the clinical significance of SWI with high resolution and its potential to guide intravenous thrombolysis in stroke patients. In this retrospective analysis, we examined 96 patients with hypertension after acute stroke in our hospital using SWI. Demographic and medical data of these 96 patients were collected. Spearman correlation analysis was performed to investigate the relationship between CMBs and the grading of WMH. A significant positive correlation was observed between CMBs and the grade of WMH (R = 0.593, P < .05). The data also revealed a superior ROC area under the curve for the modified Fazekas grading of WMH, which was 0.814 (P < .05). There is a positive correlation between CMBs and the grading of leukoaraiosis in patients with acute stroke and hypertension. The higher the degree of WMH, the more severe the microvascular lesions, increasing the likelihood of intracranial hemorrhage. SWI can provide valuable guidance for administering intravenous thrombolysis in patients with acute stroke.
    MeSH term(s) Humans ; Leukoaraiosis/diagnostic imaging ; Correlation of Data ; Retrospective Studies ; White Matter/diagnostic imaging ; Hypertension/complications ; Stroke ; Cerebral Hemorrhage/diagnostic imaging
    Language English
    Publishing date 2023-03-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000035003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Factors related to residual gallbladder calculi formation using computed tomography and magnetic resonance imaging combined with clinical data

    Zudong Yin / Yanyan Zhu / Zhangzhu Li / Xiangsen Jiang / Wei An / Liang Yin / Lei Yu

    Journal of International Medical Research, Vol

    2020  Volume 48

    Abstract: Objective We aimed to investigate risk factors related to remnant gallbladder (RGB) stones. Methods This retrospective study included 73 patients with RGB, in groups with and without RGB calculi. Univariate analyses were used to identify nine variables ... ...

    Abstract Objective We aimed to investigate risk factors related to remnant gallbladder (RGB) stones. Methods This retrospective study included 73 patients with RGB, in groups with and without RGB calculi. Univariate analyses were used to identify nine variables associated with RGB calculi: sex, age, body mass index (BMI), time to detection, surgical method, length of RGB, angle of RGB and common hepatic duct (CHD), choledocholithiasis, and remnant cholecystitis. Multivariate logistic regression was performed to assess independent predictors of RGB stones. A receiver operating characteristic (ROC) curve was used to estimate model accuracy and determine cut-off values of independent predictors. Results We enrolled 73 patients, 33 with and 40 without RGB stones. Univariate analyses showed that age, BMI, time to detection, length of RGB, angle of RGB and CHD were predictors for RGB calculi. Multivariate analyses indicated that time to detection, length of RGB, and angle of RGB and CHD were independent predictors for RGB calculi. The area under the ROC curve of the model was 0.940. Cut-off values of the three indicators were 1.5 years, 2.25 cm, and 22.5°, respectively. Conclusion Time to detection, length of RGB, and angle of RGB and CHD were independent predictors of RGB calculi.
    Keywords Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2020-09-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Factors related to residual gallbladder calculi formation using computed tomography and magnetic resonance imaging combined with clinical data.

    Yin, Zudong / Zhu, Yanyan / Li, Zhangzhu / Jiang, Xiangsen / An, Wei / Yin, Liang / Yu, Lei

    The Journal of international medical research

    2020  Volume 48, Issue 9, Page(s) 300060520958968

    Abstract: Objective: We aimed to investigate risk factors related to remnant gallbladder (RGB) stones.: Methods: This retrospective study included 73 patients with RGB, in groups with and without RGB calculi. Univariate analyses were used to identify nine ... ...

    Abstract Objective: We aimed to investigate risk factors related to remnant gallbladder (RGB) stones.
    Methods: This retrospective study included 73 patients with RGB, in groups with and without RGB calculi. Univariate analyses were used to identify nine variables associated with RGB calculi: sex, age, body mass index (BMI), time to detection, surgical method, length of RGB, angle of RGB and common hepatic duct (CHD), choledocholithiasis, and remnant cholecystitis. Multivariate logistic regression was performed to assess independent predictors of RGB stones. A receiver operating characteristic (ROC) curve was used to estimate model accuracy and determine cut-off values of independent predictors.
    Results: We enrolled 73 patients, 33 with and 40 without RGB stones. Univariate analyses showed that age, BMI, time to detection, length of RGB, angle of RGB and CHD were predictors for RGB calculi. Multivariate analyses indicated that time to detection, length of RGB, and angle of RGB and CHD were independent predictors for RGB calculi. The area under the ROC curve of the model was 0.940. Cut-off values of the three indicators were 1.5 years, 2.25 cm, and 22.5°, respectively.
    Conclusion: Time to detection, length of RGB, and angle of RGB and CHD were independent predictors of RGB calculi.
    MeSH term(s) Gallbladder ; Humans ; Lithotripsy ; Magnetic Resonance Imaging ; Retrospective Studies ; Tomography, X-Ray Computed
    Language English
    Publishing date 2020-10-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 184023-x
    ISSN 1473-2300 ; 0300-0605 ; 0142-2596
    ISSN (online) 1473-2300
    ISSN 0300-0605 ; 0142-2596
    DOI 10.1177/0300060520958968
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: COVID-19 Dynamic Computed Tomography (CT) Performance and Observation of Some Laboratory Indicators.

    Jiang, Xiangsen / Yin, Zudong / Wang, Tao / Zhai, Nailiang / Lu, Feng / Zhan, Chunhua / Han, Qizheng / Feng, Changjiang

    Medical science monitor : international medical journal of experimental and clinical research

    2020  Volume 26, Page(s) e924403

    Abstract: BACKGROUND Chest CT has an essential role in the detection and evaluation of novel coronary pneumonia (COVID-19) and has be regarded as a critical supplement for RT-PCR. This study explored the dynamic CT manifestations of COVID-19 at different times and ...

    Abstract BACKGROUND Chest CT has an essential role in the detection and evaluation of novel coronary pneumonia (COVID-19) and has be regarded as a critical supplement for RT-PCR. This study explored the dynamic CT manifestations of COVID-19 at different times and the value of some laboratory indicators for clinical guidance. MATERIAL AND METHODS This retrospective review included 44 patients who were infected with COVID-19. The dynamic chest CT and laboratory findings were obtained from electronic medical records. The intervals between onset and CT scans and the dynamic changes of the lesions were recorded. The above data were reviewed, sorted, and analyzed by using SPSS 21.0 software. RESULTS From the time of onset, the dynamic image of the lungs became more complete. Fibrous cord shadow absorption in the lungs were observed. Experimental indicators, biochemical indicators of lymphocytes, and protein series were decreased to varying degrees, while erythrocyte sedimentation, fibrinogen, and D-dimer were increased to varying degrees. CONCLUSIONS The dynamic changes of CT images of lungs of COVID-19 patients, combined with the clinical manifestations and laboratory indicators of patients, can help guide clinical diagnosis and treatment.
    MeSH term(s) Betacoronavirus ; Biomarkers ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Coronavirus Infections/diagnostic imaging ; Coronavirus Infections/pathology ; Coronavirus Infections/physiopathology ; Humans ; Image Processing, Computer-Assisted ; Lung/diagnostic imaging ; Pandemics ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/pathology ; Pneumonia, Viral/physiopathology ; Retrospective Studies ; SARS-CoV-2 ; Software ; Tomography, X-Ray Computed
    Chemical Substances Biomarkers
    Keywords covid19
    Language English
    Publishing date 2020-05-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1439041-3
    ISSN 1643-3750 ; 1234-1010
    ISSN (online) 1643-3750
    ISSN 1234-1010
    DOI 10.12659/MSM.924403
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Mechanical properties tailoring of topology optimized and selective laser melting fabricated Ti6Al4V lattice structure.

    Xu, Yangli / Zhang, Dongyun / Hu, Songtao / Chen, Runping / Gu, Yilei / Kong, Xiangsen / Tao, Jiongming / Jiang, Yijian

    Journal of the mechanical behavior of biomedical materials

    2019  Volume 99, Page(s) 225–239

    Abstract: This paper investigates the effect of porosity and unit cell size variation in topology optimized (TOP) and selective laser melting (SLM) fabricated Ti6Al4V lattice structure on the mechanical properties including compressive strength, failure mechanism ... ...

    Abstract This paper investigates the effect of porosity and unit cell size variation in topology optimized (TOP) and selective laser melting (SLM) fabricated Ti6Al4V lattice structure on the mechanical properties including compressive strength, failure mechanism and dynamic elastic modulus. Meanwhile, mathematical relations between mechanical properties and geometric parameters are obtained based on Gibson-Ashby model. The results show that both ultimate compressive strength (σ = 23∼498 MPa) and dynamic elastic modulus (E = 3.5∼55.47 GPa) of TOP lattice structures gradually decrease with the increase in porosity and unit cell size. The analysis combining experimental and numerical results indicates that TOP lattice structures are elastic-brittle porous material and have two failure mechanisms. The numerical predicted stress-strain curves are compared with the experimental ones. The numerical models incorporating the Johnson-Cook damage model could predict the slip direction of 45° failure band and ultimate compressive strength. Classical Gibson-Ashby model was used to predict the relation between relative density and mechanical properties of lattice structures. The exponential factors (n) of fitted models are obviously affected by unit cell size, which are determined by the number of unit cells in compressive test and SLM manufacturability in dynamic elastic modulus test. A 3D Modulus-Density-Unit Cell Size model is innovatively proposed, which can provide theoretical basis of tailoring orthopedic implant filled with functional gradient TOP lattice structures.
    MeSH term(s) Algorithms ; Biocompatible Materials/chemistry ; Bone and Bones/pathology ; Compressive Strength ; Elastic Modulus ; Elasticity ; Humans ; Imaging, Three-Dimensional ; Lasers ; Materials Testing ; Models, Theoretical ; Orthopedics ; Porosity ; Pressure ; Prostheses and Implants ; Stress, Mechanical ; Titanium/chemistry ; X-Ray Diffraction
    Chemical Substances Biocompatible Materials ; titanium alloy (TiAl6V4) (12743-70-3) ; Titanium (D1JT611TNE)
    Language English
    Publishing date 2019-06-21
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2378381-3
    ISSN 1878-0180 ; 1751-6161
    ISSN (online) 1878-0180
    ISSN 1751-6161
    DOI 10.1016/j.jmbbm.2019.06.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [Verteporfin inhibits proliferation, invasion and migration of MDA-MB-231 human breast cancer cells by down-regulating the expression of Yes-associated protein].

    Jiang, Yulin / Liu, Yifeng / Zhang, Zhiqian / Yang, Junhong / Ye, Xiangsen / Jin, Qianni / Chen, Tingmei

    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology

    2017  Volume 33, Issue 9, Page(s) 1223–1227

    Abstract: Objective To investigate the effects of verteporfin on the proliferation, invasion and migration of human breast cancer MDA-MB-231 cells and the underlying mechanism. Methods MDA-MB-231 cells in the logarithmic growth phase were randomly divided into ... ...

    Abstract Objective To investigate the effects of verteporfin on the proliferation, invasion and migration of human breast cancer MDA-MB-231 cells and the underlying mechanism. Methods MDA-MB-231 cells in the logarithmic growth phase were randomly divided into control group and verteporfin treatment group. After MDA-MB-231 cells were treated with (0, 4, 8, 12, 16) μmol/mL verteporfin, the minimal inhibitory concentration was determined by CCK-8 assay. After treatment with 4 μmol/mL verteporfin, the invasion and migration abilities of MDA-MB-231 cells were detected by Transwell
    MeSH term(s) Adaptor Proteins, Signal Transducing/genetics ; Antineoplastic Agents/pharmacology ; Breast Neoplasms/drug therapy ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Down-Regulation ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Neoplasm Invasiveness ; Phosphoproteins/genetics ; Porphyrins/pharmacology ; Transcription Factors ; Verteporfin
    Chemical Substances Adaptor Proteins, Signal Transducing ; Antineoplastic Agents ; Phosphoproteins ; Porphyrins ; Transcription Factors ; YAP1 protein, human ; Verteporfin (0X9PA28K43)
    Language Chinese
    Publishing date 2017-10-31
    Publishing country China
    Document type Journal Article
    ISSN 1007-8738
    ISSN 1007-8738
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: COVID-19 Dynamic Computed Tomography (CT) Performance and Observation of Some Laboratory Indicators

    Jiang, Xiangsen / Yin, Zudong / Wang, Tao / Zhai, Nailiang / Lu, Feng / Zhan, Chunhua / Han, Qizheng / Feng, Changjiang

    Med Sci Monit

    Abstract: BACKGROUND Chest CT has an essential role in the detection and evaluation of novel coronary pneumonia (COVID-19) and has be regarded as a critical supplement for RT-PCR. This study explored the dynamic CT manifestations of COVID-19 at different times and ...

    Abstract BACKGROUND Chest CT has an essential role in the detection and evaluation of novel coronary pneumonia (COVID-19) and has be regarded as a critical supplement for RT-PCR. This study explored the dynamic CT manifestations of COVID-19 at different times and the value of some laboratory indicators for clinical guidance. MATERIAL AND METHODS This retrospective review included 44 patients who were infected with COVID-19. The dynamic chest CT and laboratory findings were obtained from electronic medical records. The intervals between onset and CT scans and the dynamic changes of the lesions were recorded. The above data were reviewed, sorted, and analyzed by using SPSS 21.0 software. RESULTS From the time of onset, the dynamic image of the lungs became more complete. Fibrous cord shadow absorption in the lungs were observed. Experimental indicators, biochemical indicators of lymphocytes, and protein series were decreased to varying degrees, while erythrocyte sedimentation, fibrinogen, and D-dimer were increased to varying degrees. CONCLUSIONS The dynamic changes of CT images of lungs of COVID-19 patients, combined with the clinical manifestations and laboratory indicators of patients, can help guide clinical diagnosis and treatment.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #259653
    Database COVID19

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  9. Article ; Online: The miR-186-3p/EREG axis orchestrates tamoxifen resistance and aerobic glycolysis in breast cancer cells.

    He, Mengjia / Jin, Qianni / Chen, Cong / Liu, Yifeng / Ye, Xiangsen / Jiang, Yulin / Ji, Feihu / Qian, Husun / Gan, Delu / Yue, Shujun / Zhu, Wei / Chen, Tingmei

    Oncogene

    2019  Volume 38, Issue 28, Page(s) 5551–5565

    Abstract: Tamoxifen resistance is one of the major challenges for its medical uses in estrogen receptor (ER)-positive breast cancer. Aerobic glycolysis, an anomalous characteristic of glucose metabolism in cancer cells, has been shown to associate with the ... ...

    Abstract Tamoxifen resistance is one of the major challenges for its medical uses in estrogen receptor (ER)-positive breast cancer. Aerobic glycolysis, an anomalous characteristic of glucose metabolism in cancer cells, has been shown to associate with the resistance to chemotherapeutic agents. It remains, however, largely unclear whether and how tamoxifen resistance contributes to aerobic glycolysis in breast cancer. Here, we report that tamoxifen resistance is associated with enhanced glycolysis in ER-positive breast cancer cells. We demonstrate that EREG, an agonist of EGFR, has an important role in enhancing glycolysis via activating EGFR signaling and its downstream glycolytic genes in tamoxifen-resistant breast cancer cells. We further show that EREG is a direct target of miR-186-3p and that downregulation of miR-186-3p by tamoxifen results in EREG upregulation in tamoxifen-resistant breast cancer cells. Importantly, systemic delivery of cholesterol-modified agomiR-186-3p to mice bearing tamoxifen-resistant breast tumors effectively attenuates both tumor growth and [
    MeSH term(s) Aerobiosis ; Animals ; Antineoplastic Agents, Hormonal/pharmacology ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Down-Regulation ; Drug Resistance, Neoplasm ; Epiregulin/metabolism ; Female ; Humans ; Mice ; Mice, Nude ; MicroRNAs/metabolism ; Tamoxifen/pharmacology ; Up-Regulation ; Xenograft Model Antitumor Assays
    Chemical Substances Antineoplastic Agents, Hormonal ; EREG protein, human ; Epiregulin ; MIRN186 microRNA, human ; MicroRNAs ; Tamoxifen (094ZI81Y45)
    Language English
    Publishing date 2019-04-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639046-8
    ISSN 1476-5594 ; 0950-9232
    ISSN (online) 1476-5594
    ISSN 0950-9232
    DOI 10.1038/s41388-019-0817-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Invalidation of mitophagy by FBP1-mediated repression promotes apoptosis in breast cancer.

    Liu, Yifeng / Jiang, Yulin / Wang, Nian / Jin, Qianni / Ji, Feihu / Zhong, Changli / Zhang, Zhiqiang / Yang, Junhong / Ye, Xiangsen / Chen, Tingmei

    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

    2017  Volume 39, Issue 6, Page(s) 1010428317708779

    Abstract: Fructose-1,6-bisphosphatase 1, a rate-limiting enzyme in gluconeogenesis, was recently shown to be a tumor suppressor. However, the functions of fructose-1,6-bisphosphatase 1 in the regulation of mitophagy and apoptosis remain unknown. Here, we ... ...

    Abstract Fructose-1,6-bisphosphatase 1, a rate-limiting enzyme in gluconeogenesis, was recently shown to be a tumor suppressor. However, the functions of fructose-1,6-bisphosphatase 1 in the regulation of mitophagy and apoptosis remain unknown. Here, we investigated the effects of fructose-1,6-bisphosphatase 1 on mitophagy and apoptosis as well as their underlying mechanisms in breast cancer cells. In this work, the messenger RNA and protein expression of various molecules were determined by quantitative realtime polymerase chain reaction and western blot, respectively. Gene-expression correlations were obtained from The Cancer Genome Atlas Breast Cancer database and analyzed using cBioPortal. The levels of cellular reactive oxygen species and apoptotic index were detected by flow cytometry. The mitochondrial membrane potentials were assessed with a JC-1 fluorescent sensor. Subcellular structures were observed under a transmission electron microscope. The intracellular distribution of translocase of outer membrane 20 was detected by immunofluorescence staining. Protein-protein interactions were analyzed by immunoprecipitation. Our results indicated that fructose-1,6-bisphosphatase 1 expression was negatively correlated with autophagy level in breast cancer. Fructose-1,6-bisphosphatase 1 restrained autophagy activity by increasing the level of p62 and decreasing the levels of LC3 and Beclin 1. Additionally, fructose-1,6-bisphosphatase 1 promoted cell apoptosis by upregulating the levels of intracellular ROS and expression of pro-apoptotic proteins such as cleaved PARP, cleaved Caspase 3, and Bax and downregulating the levels of anti-apoptotic proteins such as PARP, Caspase 3, and Bcl-2. Finally, fructose-1,6-bisphosphatase 1 limited the efficient removal of diseased mitochondria and reduced the messenger RNA and protein expressions of HIF-1α, BNIP3L/NIX, and BNIP3. More importantly, fructose-1,6-bisphosphatase 1 facilitated co-action between Bcl-2 and Beclin 1, which may be important in the mechanism of fructose-1,6-bisphosphatase 1-mediated mitophagy inhibition. In summary, loss of mitophagy by fructose-1,6-bisphosphatase 1-mediated repression promotes apoptosis in breast cancer.
    MeSH term(s) Apoptosis/genetics ; Autophagy/genetics ; Beclin-1/genetics ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; DNA Helicases/genetics ; DNA-Binding Proteins/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Kaplan-Meier Estimate ; MCF-7 Cells ; Mitochondria/genetics ; Mitochondrial Degradation/genetics ; Protein Interaction Maps/genetics ; Proto-Oncogene Proteins c-bcl-2/genetics ; Reactive Oxygen Species/metabolism
    Chemical Substances Beclin-1 ; DNA-Binding Proteins ; FUBP1 protein, human ; Proto-Oncogene Proteins c-bcl-2 ; Reactive Oxygen Species ; DNA Helicases (EC 3.6.4.-)
    Language English
    Publishing date 2017-03-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605825-5
    ISSN 1423-0380 ; 0289-5447 ; 1010-4283
    ISSN (online) 1423-0380
    ISSN 0289-5447 ; 1010-4283
    DOI 10.1177/1010428317708779
    Database MEDical Literature Analysis and Retrieval System OnLINE

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