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Article ; Online: Left Gluteal Maximus Neuroma Causing Long-Standing Gluteal Pain.

Cognetti, Peter A / Levy, Emily

2023 Volume 22, Issue 3, Page(s) 76–77

Abstract: Abstract: Diagnosing buttock pain is a challenge due to complex anatomy and multiple causes. Potential pathologies range from common and benign to rare and life-threatening. Common causes for buttock pain include referred pain from the lumbar spine and ... ...

Abstract	Abstract: Diagnosing buttock pain is a challenge due to complex anatomy and multiple causes. Potential pathologies range from common and benign to rare and life-threatening. Common causes for buttock pain include referred pain from the lumbar spine and sacroiliac joint, hamstring origin tendinopathy, myofascial pain, ischiogluteal bursitis, gluteal pathology, and piriformis syndrome. Rarer causes include malignancy, bone infection, vascular anomalies, and spondyloarthropathies. Other conditions may be present concurrently in the lumbar and gluteal area, which can cloud the clinical picture. Correct diagnosis and early treatment may improve quality of life by providing a targetable reason for their distress, improving pain, and allowing the patient to get back to their activities of daily living. When treating a patient with buttock pain, it is essential to reevaluate the diagnosis when symptoms fail to improve despite appropriate intervention.Here, we discuss a case of a peripheral nerve sheath tumor found in the left gluteus medius muscle of a patient that caused persistent, debilitating buttock pain. After years of treatment for piriformis syndrome and possible spinous causes, the patient was ultimately diagnosed with a peripheral nerve sheath tumor through magnetic resonance imaging with contrast. Peripheral nerve sheath tumors are a diverse group of mostly benign tumors that can occur sporadically or associated with certain disease processes. These tumors usually present with pain, a soft tissue mass, or focal neurological deficits. Upon removal of the tumor, her gluteal pain completely resolved.
MeSH term(s)	Humans ; Female ; Activities of Daily Living ; Buttocks ; Piriformis Muscle Syndrome/complications ; Piriformis Muscle Syndrome/diagnosis ; Quality of Life ; Neuroma/complications ; Neuroma/diagnosis ; Nerve Sheath Neoplasms
Language	English
Publishing date	2023-03-01
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2080040-X
ISSN	1537-8918 ; 1537-890X
ISSN (online)	1537-8918
ISSN	1537-890X
DOI	10.1249/JSR.0000000000001043
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Article ; Online: Posterior reversible encephalopathy syndrome in the setting of IgA vasculitis.

Fanous, Noah / Clarke, Emily / Levy, Moise L

Pediatric dermatology

2024

Abstract: IgA vasculitis (IgAV), formerly known as Henoch-Scholein purpura, is a small vessel vasculitis, most commonly seen in pediatric patients, that can affect numerous internal organs including the kidneys, lungs, gastrointestinal tract, and the central ... ...

Abstract	IgA vasculitis (IgAV), formerly known as Henoch-Scholein purpura, is a small vessel vasculitis, most commonly seen in pediatric patients, that can affect numerous internal organs including the kidneys, lungs, gastrointestinal tract, and the central nervous system (CNS). CNS manifestations of this condition include hypertensive encephalopathy, thrombosis, optic neuropathy, seizures, CNS vasculitis, and a more recently described phenomenon known as posterior reversible encephalopathy syndrome (PRES). Symptoms of PRES include hypertension, altered mental status, and seizures caused by vasogenic disruption of the blood-brain barrier, and the condition is diagnosed by characteristic edema-related gray-white matter changes in the parieto-occipital lobes on magnetic resonance imaging. Herein, we present a rare case of PRES as a presenting sign of IgAV to increase awareness about this unusual association.
Language	English
Publishing date	2024-02-18
Publishing country	United States
Document type	Letter
ZDB-ID	605539-4
ISSN	1525-1470 ; 0736-8046
ISSN (online)	1525-1470
ISSN	0736-8046
DOI	10.1111/pde.15569
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Article ; Online: A game of raids: Expanding on a game theoretical approach utilising the prisoner's dilemma and ethnography in situ.

Jeffries, Emily M L / Wright, Sarah E / Lew-Levy, Sheina

The Behavioral and brain sciences

2024 Volume 47, Page(s) e14

Abstract: In this commentary, we set out the specifics of how Glowacki's game theoretical framework for the evolution of peace could be incorporated within broader cultural evolutionary approaches. We outline a formal proposal for prisoner's dilemma games ... ...

Abstract	In this commentary, we set out the specifics of how Glowacki's game theoretical framework for the evolution of peace could be incorporated within broader cultural evolutionary approaches. We outline a formal proposal for prisoner's dilemma games investigating raid-based conflict. We also centre an ethnographic lens to understand the norms surrounding war and peace in intergroup interactions in small-scale communities.
MeSH term(s)	Humans ; Prisoner Dilemma ; Cooperative Behavior ; Game Theory ; Anthropology, Cultural ; Cultural Evolution
Language	English
Publishing date	2024-01-15
Publishing country	England
Document type	Journal Article
ZDB-ID	423721-3
ISSN	1469-1825 ; 0140-525X
ISSN (online)	1469-1825
ISSN	0140-525X
DOI	10.1017/S0140525X23002510
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Article: Infantile transient smooth muscle contraction of the skin in a 1-month-old girl.

Clarke, Emily L / Fanous, Noah / Shu, Nova / Levy, Moise L

JAAD case reports

2023 Volume 42, Page(s) 72–73

Language	English
Publishing date	2023-10-20
Publishing country	United States
Document type	Case Reports
ZDB-ID	2834220-3
ISSN	2352-5126
ISSN	2352-5126
DOI	10.1016/j.jdcr.2023.09.035
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Article ; Online: Recognizing neonatal refeeding syndrome and thiamin supplementation: A case report.

Bradley, Caitlin / Hansen, Anne / Levy, Philip / Hashim, Emily

JPEN. Journal of parenteral and enteral nutrition

2023 Volume 47, Issue 3, Page(s) 437–441

Abstract: Refeeding syndrome (RS) is a condition characterized by electrolyte derangements, thiamin deficiency, and organ dysfunction after the provision of nutrition to an individual who had been deprived of nutrients. Published guidelines outlining the ... ...

Abstract	Refeeding syndrome (RS) is a condition characterized by electrolyte derangements, thiamin deficiency, and organ dysfunction after the provision of nutrition to an individual who had been deprived of nutrients. Published guidelines outlining the recognition and definition of RS exist for adult and children, but there are limited newborn-specific guidelines because of a paucity of available literature and variation in reporting. We describe a small-for-gestational-age, full-term newborn with neonatal encephalopathy who underwent therapeutic hypothermia. Electrolyte derangements and lactic acidosis developed and persisted after the introduction of intravenous nutrition. After the exclusion of other etiologies, neonatal RS was suspected, and the newborn was treated with thiamin. We provide a brief review of the current literature on neonatal RS, present a case report consistent with neonatal RS, and provide suggestions for the utility of thiamin replacement in newborns with suspected neonatal RS.
MeSH term(s)	Child ; Adult ; Infant, Newborn ; Humans ; Thiamine/therapeutic use ; Refeeding Syndrome/etiology ; Thiamine Deficiency/drug therapy ; Thiamine Deficiency/etiology ; Electrolytes ; Dietary Supplements
Chemical Substances	Thiamine (X66NSO3N35) ; Electrolytes
Language	English
Publishing date	2023-02-01
Publishing country	United States
Document type	Case Reports
ZDB-ID	800861-9
ISSN	1941-2444 ; 0148-6071
ISSN (online)	1941-2444
ISSN	0148-6071
DOI	10.1002/jpen.2474
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Zs.A 1524: Show issues

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Book: Oxford guide to imagery in cognitive therapy

Hackmann, Ann / Bennett-Levy, James / Holmes, Emily A.

(Oxford guides in cognitive behavioural therapy)

2011

Title variant	Imagery in cognitive therapy
Author's details	Ann Hackmann ; James Bennett-Levy ; Emily A. Holmes
Series title	Oxford guides in cognitive behavioural therapy
Language	English
Size	XLII, 233 S. : Ill., graph. Darst., 25 cm
Publisher	Oxford Univ. Press
Publishing place	Oxford u.a.
Publishing country	Great Britain
Document type	Book
Note	Hier auch später erschienene, unveränderte Nachdrucke
HBZ-ID	HT016844331
ISBN	978-0-19-923402-8 ; 0-19-923402-7
Database	Catalogue ZB MED Medicine, Health

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Shelf mark	Loan status	Location
2011 A 2120	order for loan	Magazin

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Article: Loss of postsynaptic NMDARs drives nanoscale reorganization of Munc13-1 and PSD-95.

Dharmasri, Poorna A / DeMarco, Emily M / Anderson, Michael C / Levy, Aaron D / Blanpied, Thomas A

bioRxiv : the preprint server for biology

2024

Abstract: Nanoscale protein organization within the active zone (AZ) and post-synaptic density (PSD) influences synaptic transmission. Nanoclusters of presynaptic Munc13-1 are associated with readily releasable pool size and neurotransmitter vesicle priming, while ...

Abstract	Nanoscale protein organization within the active zone (AZ) and post-synaptic density (PSD) influences synaptic transmission. Nanoclusters of presynaptic Munc13-1 are associated with readily releasable pool size and neurotransmitter vesicle priming, while postsynaptic PSD-95 nanoclusters coordinate glutamate receptors across from release sites to control their opening probability. Nanocluster number, size, and protein density vary between synapse types and with development and plasticity, supporting a wide range of functional states at the synapse. Whether or how the receptors themselves control this critical architecture remains unclear. One prominent PSD molecular complex is the NMDA receptor (NMDAR). NMDARs coordinate several modes of signaling within synapses, giving them the potential to influence synaptic organization through direct protein interactions or through signaling. We found that loss of NMDARs results in larger synapses that contain smaller, denser, and more numerous PSD-95 nanoclusters. Intriguingly, NMDAR loss also generates retrograde reorganization of the active zone, resulting in denser, more numerous Munc13-1 nanoclusters, more of which are aligned with PSD-95 nanoclusters. Together, these changes to synaptic nanostructure predict stronger AMPA receptor-mediated transmission in the absence of NMDARs. Notably, while prolonged antagonism of NMDAR activity increases Munc13-1 density within nanoclusters, it does not fully recapitulate these trans-synaptic effects. Thus, our results confirm that NMDARs play an important role in maintaining pre- and postsynaptic nanostructure and suggest that both decreased NMDAR expression and suppressed NMDAR activity may exert distinct effects on synaptic function, yet through unique architectural mechanisms.
Language	English
Publishing date	2024-01-12
Publishing country	United States
Document type	Preprint
DOI	10.1101/2024.01.12.574705
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Article ; Online: Clinical decision-making processes among graduate nurses, specialist nurses and nurse practitioners A collaborative international study.

Levy-Malmberg, Rika / Boman, Erika / Lehwaldt, Daniela / Fagerström, Lisbeth / Lockwood, Emily B

International nursing review

2024

Abstract: Aim: To explore clinical decision-making by comparing the processes used by three groups of nurses in the emergency departments of three hospitals: in Norway, Finland and Ireland.: Background: Clinical decision-making in an emergency department ... ...

Abstract	Aim: To explore clinical decision-making by comparing the processes used by three groups of nurses in the emergency departments of three hospitals: in Norway, Finland and Ireland. Background: Clinical decision-making in an emergency department environment is a complex process often occurring in times of crisis. It is an important aspect contributing to the quality of care. However, empirical research is limited regarding the decision-making process in different nursing roles. Methods: In accordance with the consolidated criteria for reporting qualitative research, a qualitative and observational study was conducted to explore clinical decision-making by comparing the processes used by three groups of nurses in the emergency departments of three hospitals: in Norway, Finland and Ireland. Six Registered Nurses, six Nurse Specialists and six Nurse Practitioners were observed. A total of 40 hours of observation was made at each setting according to a structured observation guideline, followed by clarifying questions. The data material was analysed by means of a qualitative manifest and latent content analysis. Results: Three themes arose: acting in accordance with routines, previous experience and intuition; considering patient experience; and facilitating new alternatives based on critical thinking. The Registered Nurses mainly used the first approach, the Nurse Specialists used the first and the second approaches, and the Nurse Practitioners used all three approaches. Conclusions: The results highlight the differences in decision-making processes between these groups. Nurse Practitioners were the only group that facilitated and evaluated new alternatives using their clinical autonomy, such as stepping up and making independent and collaborative decision-making. Implication: The results can be used in countries developing advanced practice nursing education and defining their scope of practice to inform stakeholders.
Language	English
Publishing date	2024-03-07
Publishing country	England
Document type	Journal Article
ZDB-ID	80342-x
ISSN	1466-7657 ; 0020-8132
ISSN (online)	1466-7657
ISSN	0020-8132
DOI	10.1111/inr.12951
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Article ; Online: Mediational pathways exploring the link between adverse childhood experiences and physical health in a transgender population.

Strenth, Chance R / Smith, Margaret / Gonzalez, Leo / Grant, Abigail / Thakur, Bhaskar / Levy Kamugisha, Emily I

Child abuse & neglect

2024 Volume 149, Page(s) 106678

Abstract: Background: Adverse childhood experiences (ACEs) consist of instances of abuse, neglect, or household dysfunction occurring before adulthood. Prevalence rates of ACEs are higher among specific populations, including gender minorities. In addition to ... ...

Abstract	Background: Adverse childhood experiences (ACEs) consist of instances of abuse, neglect, or household dysfunction occurring before adulthood. Prevalence rates of ACEs are higher among specific populations, including gender minorities. In addition to ACEs, transgender individuals (TG) face many personal, social, and structural factors that have the potential to negatively impact their physical health. Objective: This study examines exploratory mediational pathways between ACEs and two health outcomes (i.e., general health and days physically ill) in TG. Mediators include everyday discrimination, social support, gender non-affirmation, and mental distress. Methods: Cross-sectional data from the U.S. Transgender Population Health Survey (TransPop) was used to conduct a serial/parallel mediation analysis. The TransPop survey included a total of 274 TG. Results: For both outcome variables, the same three indirect pathways were significant. First, ACEs were associated with increased mental distress, which was associated with a decrease in general health and an increase in days physically ill. Second, ACEs were associated with increased discrimination, which was associated with increased mental distress, and this was associated with a decrease in general health and an increase in days physically ill. Finally, ACEs were associated with discrimination, which was associated with increased gender non-affirmation which was associated with increased mental distress, and this was associated with a decrease in general health and an increase in days physically ill. Conclusion: Interventions focused on reducing discrimination, gender non-affirmation, and poor mental health may be vital to improving the health of TG and to mitigating the indirect role of ACEs on TG health.
MeSH term(s)	Humans ; Child ; Adult ; Adverse Childhood Experiences ; Transgender Persons ; Cross-Sectional Studies ; Child Abuse/psychology ; Health Surveys
Language	English
Publishing date	2024-02-02
Publishing country	England
Document type	Journal Article
ZDB-ID	799143-5
ISSN	1873-7757 ; 0145-2134
ISSN (online)	1873-7757
ISSN	0145-2134
DOI	10.1016/j.chiabu.2024.106678
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Article ; Online: Expert Guidance on Off-Label Use of Hybrid Closed-Loop Therapy in Pregnancies Complicated by Diabetes.

Szmuilowicz, Emily D / Levy, Carol J / Buschur, Elizabeth O / Polsky, Sarit

Diabetes technology & therapeutics

2023 Volume 25, Issue 5, Page(s) 363–373

Abstract: Automated insulin delivery (AID) systems have established benefits in terms of glycemic control, health outcomes, and quality of life and are strongly recommended for people with type 1 diabetes outside of pregnancy. While evidence for use of ... ...

Abstract	Automated insulin delivery (AID) systems have established benefits in terms of glycemic control, health outcomes, and quality of life and are strongly recommended for people with type 1 diabetes outside of pregnancy. While evidence for use of investigational AID systems during pregnancy is promising, data and guidance are still needed regarding use of commercially available systems during pregnancy. Unfortunately, none of the hybrid closed-loop (HCL) systems that are currently available in the United States have glucose targets that are as aggressive as pregnancy glycemic targets, none have a pregnancy-specific algorithm, and none are approved for use during pregnancy. As such, any use of these systems during pregnancy is considered off-label in the United States and would be "assisted" by provider/user techniques. Despite these limitations, many women conceive while using clinically available HCL systems and may be hesitant to cease use during pregnancy. Achievement of strict pregnancy glycemic targets can be difficult, and it is conceivable that selective off-label use of clinically available HCL systems in some women could lead to improved glycemia. We herein offer expert guidance based on clinical experience and available case reports on how to identify appropriate candidates for HCL therapy in pregnancy, how to counsel pregnant women with diabetes on the potential risks and benefits of HCL therapy during pregnancy, and how to manage commercially available systems off-label throughout gestation in an assisted HCL approach.
MeSH term(s)	Female ; Humans ; Pregnancy ; Hypoglycemic Agents/therapeutic use ; Off-Label Use ; Insulin/therapeutic use ; Quality of Life ; Blood Glucose ; Insulin Infusion Systems ; Diabetes Mellitus, Type 1/drug therapy ; Blood Glucose Self-Monitoring
Chemical Substances	Hypoglycemic Agents ; Insulin ; Blood Glucose
Language	English
Publishing date	2023-03-01
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1452816-2
ISSN	1557-8593 ; 1520-9156
ISSN (online)	1557-8593
ISSN	1520-9156
DOI	10.1089/dia.2022.0540
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