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  1. Article: Analysis of the contribution of sport events to sustainable development: Impacts, support and resident's perception.

    Parra-Camacho, David / González-Serrano, María Huertas / Alguacil Jiménez, Mario / Jiménez-Jiménez, Pablo

    Heliyon

    2023  Volume 9, Issue 11, Page(s) e22033

    Abstract: The current study intends to evaluate the link between the affects observed by citizens on athletic events, the perception of their contribution to municipalities' sustainable development, and support for their celebration. A total of 2049 inhabitants ... ...

    Abstract The current study intends to evaluate the link between the affects observed by citizens on athletic events, the perception of their contribution to municipalities' sustainable development, and support for their celebration. A total of 2049 inhabitants from the Valencian Community's three provincial capitals (Spain) took part in this study, which used a stratified random sample with proportionate allocation. The causal association model fit well, with RMSEA = 0.044, NNFI = 0.94, CFI = 0.95, and IFI = 0.95. The study's findings demonstrate that residents' perceptions of the positive and negative impacts caused by sporting events in their communities are an antecedent that explains how these events contribute to sustainable urban development. A positive relationship between perceived sustainable development and support for the hosting of sport events in these localities was also found. These results highlight the need to promote sustainable management development of any sporting event to increase local support from the residents.
    Language English
    Publishing date 2023-11-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e22033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The impact of a multicomponent training program on physical fitness and joint injuries in Spanish male professional soccer players.

    Jiménez-Rubio, Sergio / Raya-González, Javier / Lobo-Triviño, David / García-Calvo, Tomás

    Journal of sports sciences

    2024  Volume 41, Issue 21, Page(s) 1934–1943

    Abstract: This study aimed to assess the effects of a multicomponent training program (ProSAS) on selected measures of physical fitness and joint injuries in Spanish male professional soccer players. Twenty-six professional soccer players (age: 25.2 ± 3.1 years) ... ...

    Abstract This study aimed to assess the effects of a multicomponent training program (ProSAS) on selected measures of physical fitness and joint injuries in Spanish male professional soccer players. Twenty-six professional soccer players (age: 25.2 ± 3.1 years) were randomly assigned to either the experimental (EG;
    MeSH term(s) Humans ; Male ; Young Adult ; Adult ; Soccer/injuries ; Physical Fitness ; Lower Extremity ; Leg ; Athletic Performance
    Language English
    Publishing date 2024-01-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 995528-8
    ISSN 1466-447X ; 0264-0414
    ISSN (online) 1466-447X
    ISSN 0264-0414
    DOI 10.1080/02640414.2024.2307780
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Lesson learned in pediatric haploidentical transplantation in a low-resource environment: delivering melphalan IV and using low dose radiation reduce graft failure.

    Jiménez-Antolinez, Valentine / Colunga-Pedraza, Julia / Gómez-De León, Andrés / González-Lopez, Elias / Gómez-Almaguer, David / González-Llano, Oscar

    Hematology (Amsterdam, Netherlands)

    2024  Volume 29, Issue 1, Page(s) 2335417

    Abstract: Objectives: ...

    Abstract Objectives:
    MeSH term(s) Humans ; Child ; Melphalan ; Prospective Studies ; Transplantation, Haploidentical ; Busulfan ; Hematologic Neoplasms
    Chemical Substances Melphalan (Q41OR9510P) ; Busulfan (G1LN9045DK)
    Language English
    Publishing date 2024-04-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 1341428-8
    ISSN 1607-8454 ; 1024-5332 ; 1024-5340
    ISSN (online) 1607-8454
    ISSN 1024-5332 ; 1024-5340
    DOI 10.1080/16078454.2024.2335417
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Reactive oxidant species induced by antifungal drugs: identity, origins, functions, and connection to stress-induced cell death.

    Gonzalez-Jimenez, Irene / Perlin, David S / Shor, Erika

    Frontiers in cellular and infection microbiology

    2023  Volume 13, Page(s) 1276406

    Abstract: Reactive oxidant species (ROS) are unstable, highly reactive molecules that are produced by cells either as byproducts of metabolism or synthesized by specialized enzymes. ROS can be detrimental, e.g., by damaging cellular macromolecules, or beneficial, ... ...

    Abstract Reactive oxidant species (ROS) are unstable, highly reactive molecules that are produced by cells either as byproducts of metabolism or synthesized by specialized enzymes. ROS can be detrimental, e.g., by damaging cellular macromolecules, or beneficial, e.g., by participating in signaling. An increasing body of evidence shows that various fungal species, including both yeasts and molds, increase ROS production upon exposure to the antifungal drugs currently used in the clinic: azoles, polyenes, and echinocandins. However, the implications of these findings are still largely unclear due to gaps in knowledge regarding the chemical nature, molecular origins, and functional consequences of these ROS. Because the detection of ROS in fungal cells has largely relied on fluorescent probes that lack specificity, the chemical nature of the ROS is not known, and it may vary depending on the specific fungus-drug combination. In several instances, the origin of antifungal drug-induced ROS has been identified as the mitochondria, but further experiments are necessary to strengthen this conclusion and to investigate other potential cellular ROS sources, such as the ER, peroxisomes, and ROS-producing enzymes. With respect to the function of the ROS, several studies have shown that they contribute to the drugs' fungicidal activities and may be part of drug-induced programmed cell death (PCD). However, whether these "pro-death" ROS are a primary consequence of the antifungal mechanism of action or a secondary consequence of drug-induced PCD remains unclear. Finally, several recent studies have raised the possibility that ROS induction can serve an adaptive role, promoting antifungal drug tolerance and the evolution of drug resistance. Filling these gaps in knowledge will reveal a new aspect of fungal biology and may identify new ways to potentiate antifungal drug activity or prevent the evolution of antifungal drug resistance.
    MeSH term(s) Antifungal Agents/pharmacology ; Antifungal Agents/therapeutic use ; Reactive Oxygen Species/metabolism ; Oxidants ; Echinocandins/pharmacology ; Apoptosis
    Chemical Substances Antifungal Agents ; Reactive Oxygen Species ; Oxidants ; Echinocandins
    Language English
    Publishing date 2023-10-12
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2023.1276406
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Impact of breastfeeding on ICU admissions and need for mechanical ventilation in infants younger than 6 months with RSV+ bronchiolitis. An observational study.

    Jiménez-Nogueira, Esperanza / Bueno-Rebollo, Cristina / García-Jerez, Beatriz / Callejón-Fernández, Elia / Díaz-Torres, Mateo Jesús / González-Jiménez, Yolanda / Lozano-Paniagua, David / Juárez-Marruecos, Patricia / Nievas-Soriano, Bruno José / Bonillo-Perales, Antonio

    Pediatric pulmonology

    2024  

    Abstract: Introduction: This work aimed to analyze whether breastfeeding is a predictive factor for admission to ICU or needing mechanical ventilation in children under 6 months with RSV+ respiratory infection.: Methods: A retrospective cohort study was ... ...

    Abstract Introduction: This work aimed to analyze whether breastfeeding is a predictive factor for admission to ICU or needing mechanical ventilation in children under 6 months with RSV+ respiratory infection.
    Methods: A retrospective cohort study was performed in three hospitals. Binary and multiple logistic regression analyses were performed to evaluate the association of variables with admission to the ICU or receiving mechanical ventilation.
    Results: We analyzed 414 admissions, of which 293 (70.8%) had received breastfeeding, 43 (8.1%) were admitted to the ICU, and 26 (5.4%) required mechanical ventilation. Bivariate analysis showed that breastfeeding for at least 15 days and a longer duration of breastfeeding were associated with a lower risk of admission to the ICU and requiring mechanical ventilation. Multivariate analysis showed that not having been breastfed for at least 1 month was predictive of ICU admission; not having been breastfed for at least 2 months was predictive of needing mechanical ventilation.
    Conclusions: Breastfeeding for as little as 15-28 days could be associated with a lower risk of ICU admission and requiring mechanical ventilation in infants younger than 6 months admitted for RSV+ bronchiolitis. Since breastfeeding is one of the few protective factors that can be promoted, this finding is relevant for current clinical practice and the development of health promotion programs. Future studies can compare their results to ours.
    Language English
    Publishing date 2024-05-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632784-9
    ISSN 1099-0496 ; 8755-6863
    ISSN (online) 1099-0496
    ISSN 8755-6863
    DOI 10.1002/ppul.27036
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  6. Article: Development and validation of EDU-COV-NEE-NEAE questionnaire to measure educational response, ICT usage and impact of COVID-19 pandemic on students with special educational needs.

    Rodríguez-Jiménez, María C / Pérez Jorge, David / González-Contreras, Ana I / Larumbe Zabala, Eneko

    Heliyon

    2023  Volume 9, Issue 9, Page(s) e19231

    Abstract: The COVID-19 pandemic forced changes in the educational response, which involved the intensive use of Information and Communication Technology (ICT) skills, among other interventions. The circumstances required both families and teachers to make an extra ...

    Abstract The COVID-19 pandemic forced changes in the educational response, which involved the intensive use of Information and Communication Technology (ICT) skills, among other interventions. The circumstances required both families and teachers to make an extra effort to adapt to a reality that was expected to last for a long time. These changes had a special impact on students with Specific Needs of Educational Support (SNES) and Special Educational Needs (SEN). This study aimed to design and validate a questionnaire to assess the impact of the online training model used during the pandemic on teachers of students with SNES and SEN. We used qualitative, exploratory, and confirmatory factor analyses. The final 16-item scale was composed of three factors. Factor1, was labeled as "Educational Response.", factor2 was labeled "ICT Usage and Online Teaching," and Factor 3 was labeled "Impact." The questionnaire demonstrated good validity and reliability. This short questionnaire is recommended for assessing or monitoring the impact of changes in educational interventions involving ICT competencies due to COVID-19. However, they can also be easily adapted to similar circumstances or educational settings.
    Language English
    Publishing date 2023-08-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e19231
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Co-existence of peripheral fatigue of the knee extensors and jump potentiation after an incremental running test to exhaustion in endurance trained male runners.

    Márquez, Gonzalo / González-Hernandez, Jorge / Jiménez-Reyes, Pedro / Colomer-Poveda, David / Boullosa, Daniel

    Frontiers in sports and active living

    2023  Volume 5, Page(s) 1267593

    Abstract: The aim of the present study was to investigate the effect of an incremental running exercise until exhaustion on twitch responses and jump capacity in endurance trained runners. For this purpose, 8 experienced endurance male runners were required to ... ...

    Abstract The aim of the present study was to investigate the effect of an incremental running exercise until exhaustion on twitch responses and jump capacity in endurance trained runners. For this purpose, 8 experienced endurance male runners were required to perform neuromuscular function tests before and after a submaximal running bout (control condition -CTR-) or an incremental running test to volitional exhaustion (experimental conditions -EXP-). The twitch interpolation technique was used to assess voluntary activation and muscle contractile properties before and after each condition (CTR and EXP). Countermovement jump was also used to assess the stretch-shortening cycle function before and after both conditions. In addition, rating of perceived exertion, heart rate, blood lactate and skin temperature were also recorded. Only EXP improved jump performance, however, it was also accompanied by a reduction in maximal voluntary contraction and the peak twitch force of the knee extensors evoked by electrical stimulation at 10 Hz (Db10). It is likely that reductions in maximal voluntary contraction may be related to an excitation-contraction coupling failure (i.e. low-frequency fatigue) as suggest the reduction in the Db10. The current results confirm that acute changes in jump performance may not be appropriate to evaluate acute fatigue in endurance trained runners.
    Language English
    Publishing date 2023-11-09
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2624-9367
    ISSN (online) 2624-9367
    DOI 10.3389/fspor.2023.1267593
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Electrical and Joule Heating Capabilities of Multifunctional Coatings based on Recycled Carbon Fiber from Prepreg Scrap.

    Martinez-Diaz, David / Espeute, Emma / Jiménez-Suárez, Alberto / Prolongo, Silvia González

    ACS omega

    2023  Volume 8, Issue 49, Page(s) 46548–46559

    Abstract: The continuous growth in the use of preimpregnated semielaborated products to manufacture continuous carbon fiber-reinforced polymer parts has led the industry to face an important challenge in the management of the prepreg scrap, as the amount of waste ... ...

    Abstract The continuous growth in the use of preimpregnated semielaborated products to manufacture continuous carbon fiber-reinforced polymer parts has led the industry to face an important challenge in the management of the prepreg scrap, as the amount of waste produced can reach almost 75% due to the inefficiency of the cutting phase. In this context, this industry is pushed to move toward a circular economy approach by conferring a new use to their waste. The main problem arises from the fact that shortening carbon fiber leads to nonefficient mechanical reinforcement and that other thermal or chemical recycling approaches are environmentally hazardous. In this work, mechanical recycling of carbon fiber prepregs from expired virgin prepregs or scrap from an automated manufacturing operation is proposed as an economical and environmentally efficient method to obtain multifunctional coatings with Joule effect heating capabilities, which are demanded by different industries as a high-value product. As a coating, mechanical performance is not so relevant; nevertheless, obtaining high electrical conductivity by the incorporation of proper size and distributed short recycled carbon fiber can lead to a self-heating coating that could be used for anti- and deicing purposes or any other thermally activated function with very low power consumption. In this way, electrical conductivities up to 2 S/m were obtained, which allowed for achieving temperatures of 200 °C by the Joule effect in all samples in less than 17 s by the application of voltages below 48 V for bulk materials and 100 V for the coating.
    Language English
    Publishing date 2023-11-28
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c05413
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Uses and Applications of Docosahexaenoic Acid (DHA) in Pediatric Gastroenterology: Current Evidence and New Perspective.

    Jiménez, David González / García, Carlos Bousoño / Martín, Juan Jose Diaz

    Current pediatric reviews

    2021  Volume 17, Issue 4, Page(s) 329–335

    Abstract: In this paper, we will review the dietary allowances of these fatty acids in the paediatric population, and also the indications in different pathologies within the field of pediatric gastroenterology. Finally, we will try to explain the reasons that may ...

    Abstract In this paper, we will review the dietary allowances of these fatty acids in the paediatric population, and also the indications in different pathologies within the field of pediatric gastroenterology. Finally, we will try to explain the reasons that may justify the difficulty in translating good results in experimental studies to the usual clinical practice. This "good results" may be too little to be detected or there may be other causes but misinterpreted as effects of DHA.
    MeSH term(s) Child ; Dietary Supplements ; Docosahexaenoic Acids/therapeutic use ; Gastroenterology ; Humans
    Chemical Substances Docosahexaenoic Acids (25167-62-8)
    Language English
    Publishing date 2021-03-02
    Publishing country United Arab Emirates
    Document type Journal Article
    ISSN 1875-6336
    ISSN (online) 1875-6336
    DOI 10.2174/1573396317666210303151947
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Influence of 12-Week Concurrent Training on Exosome Cargo and Its Relationship with Cardiometabolic Health Parameters in Men with Obesity.

    Estébanez, Brisamar / Amaro-Gahete, Francisco J / Gil-González, Cristina / González-Gallego, Javier / Cuevas, María J / Jiménez-Pavón, David

    Nutrients

    2023  Volume 15, Issue 13

    Abstract: Exosome release varies depending on the physiological state of the cell, so they could play a fundamental role in obesity, the biggest pandemic in today's societies. The beneficial effects that physical activity has both on weight and cardiovascular ... ...

    Abstract Exosome release varies depending on the physiological state of the cell, so they could play a fundamental role in obesity, the biggest pandemic in today's societies. The beneficial effects that physical activity has both on weight and cardiovascular parameters may be mediated by exosomes released in response to exercise. Thus, we aimed (I) to study the influence of a 12-week CT intervention on exosome cargo modifications in men with obesity and (II) to determine whether changes in exosomes after the intervention were related to changes in cardiometabolic health parameters in our cohorts. An experimental, controlled design was performed in twelve (nine with valid data) adult male obese patients (mean values: 41.6 years old, 97.6 kg and 32.4 kg/m
    MeSH term(s) Adult ; Humans ; Male ; Exosomes ; Obesity/therapy ; Exercise ; Exercise Therapy ; Cardiovascular Diseases
    Language English
    Publishing date 2023-07-07
    Publishing country Switzerland
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15133069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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