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Article ; Online: Analysis of potential risks of clinical application of Yi Dian Hong and its proprietary Chinese medicines: A review.

Chen, Gongzhen / Mao, Leiming / Xia, Huyan / Zhu, Lei / Huang, Jiamin / Lu, Yingmin / Liu, Xin / Tang, Ting

2024 Volume 103, Issue 4, Page(s) e36860

Abstract: Yi Dian Hong, belonging to the Asteraceae family, finds widespread use ... swelling, and cooling the blood. Modern medical research has revealed that Yi Dian Hong and its proprietary ... regulating immune-related molecules. However, studies have identified that the primary component of Yi Dian ...

Abstract	Yi Dian Hong, belonging to the Asteraceae family, finds widespread use in traditional Chinese medicine for its effectiveness in clearing heat, detoxifying, promoting blood circulation, reducing swelling, and cooling the blood. Modern medical research has revealed that Yi Dian Hong and its proprietary Chinese medicines possess biological functions such as inhibiting tumor-specific angiogenesis and regulating immune-related molecules. However, studies have identified that the primary component of Yi Dian Hong contains pyrrolizidine alkaloids (PAs), a toxic substance with potential risks to the liver, lungs, genes, and a propensity for carcinogenicity. Many countries impose strict controls on the content of PAs in herbal medicines and products. Unfortunately, China currently lacks relevant content standards, thereby introducing greater clinical application risks. To ensure the safety of clinical use of Yi Dian Hong, this review will analyze the risk associated with Yi Dian Hong and its proprietary Chinese medicines in clinical applications based on the PAs content in these medicines and provide recommendations.
MeSH term(s)	Humans ; Medicine, Chinese Traditional/adverse effects ; Drugs, Chinese Herbal/adverse effects ; Plants, Medicinal ; China ; Pyrrolizidine Alkaloids
Chemical Substances	Drugs, Chinese Herbal ; Pyrrolizidine Alkaloids
Language	English
Publishing date	2024-01-26
Publishing country	United States
Document type	Review ; Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000036860
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Article ; Online: Bu Shen Yi Sui Capsule Promotes Myelin Repair by Modulating the Transformation of A1/A2 Reactive Astrocytes

Zha, Zheng / Liu, Yi-Jiang / Liu, Si-Si / Zhang, Nan / Li, Jun-Ling / Qi, Fang / Jin, Liang-Yun / Xue, Bing / Yang, Tao / Fan, Yong-Ping / Zhao, Hui / Wang, Lei

Oxidative medicine and cellular longevity

2022 Volume 2022, Page(s) 3800004

Abstract: Background/ ... ...

Abstract	Background/Aims
MeSH term(s)	Animals ; Astrocytes/metabolism ; Central Nervous System ; Complement C1q/metabolism ; Complement C1q/pharmacology ; Mice ; Mice, Inbred C57BL ; MicroRNAs/metabolism ; Multiple Sclerosis/drug therapy ; Multiple Sclerosis/metabolism ; Myelin Sheath ; Tumor Necrosis Factor-alpha/metabolism
Chemical Substances	MicroRNAs ; Tumor Necrosis Factor-alpha ; Complement C1q (80295-33-6)
Language	English
Publishing date	2022-09-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2455981-7
ISSN	1942-0994 ; 1942-0994
ISSN (online)	1942-0994
ISSN	1942-0994
DOI	10.1155/2022/3800004
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Article ; Online: Reduction in gefitinib resistance mediated by Yi-Fei San-Jie pill in non-small cell lung cancer through regulation of tyrosine metabolism, cell cycle, and the MET/EGFR signaling pathway.

Yang, Cai-Zhi / Guo, Wei / Wang, Yi-Fan / Hu, Lei-Hao / Wang, Jing / Luo, Jia-Min / Yao, Xiao-Hui / Liu, Shan / Tao, Lan-Ting / Sun, Ling-Ling / Lin, Li-Zhu

Journal of ethnopharmacology

2023 Volume 314, Page(s) 116566

Abstract: Ethnopharmacological relevance: The Chinese herbal prescription Yi-Fei San-Jie pill (YFSJ) has ...

Abstract	Ethnopharmacological relevance: The Chinese herbal prescription Yi-Fei San-Jie pill (YFSJ) has been used for adjuvant treatment in patients with lung cancer for a long time. Aim of the study: Reports have indicated that the combination of gefitinib (Gef) with YFSJ inhibits the proliferation of EGFR-TKI-resistant cell lines by enhancing cellular apoptosis and autophagy in non-small cell lung cancer (NSCLC). However, the molecular mechanisms underlying the effect of YFSJ on EGFR-TKI resistance and related metabolic pathways remain to be explored. Materials and methods: In our report, ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), metabolomics, network pharmacology, bioinformatics, and biological analysis methods were used to investigate the mechanism. Results: The UPLC-MS/MS data identified 42 active compounds of YFSJ extracts. YFSJ extracts can enhance the antitumor efficacy of Gef without hepatic and renal toxicity in vivo. The analysis of the metabolomics pathway enrichment revealed that YFSJ mainly affected the tyrosine metabolism pathway in rat models. Moreover, YFSJ has been shown to reverse Gef resistance and improve the effects of Gef on the cellular viability, migration capacity, and cell cycle arrest of NSCLC cell lines with EGFR mutations. The results of network pharmacology and molecular docking analyses revealed that tyrosine metabolism-related active compounds of YFSJ affect EGFR-TKIs resistance in NSCLC by targeting cell cycle and the MET/EGFR signaling pathway; these findings were validated by western blotting and immunohistochemistry. Conclusions: YFSJ inhibits NSCLC by inducing cell cycle arrest in the G1/S phase to suppress tumor growth, cell viability, and cell migration through synergistic effects with Gef via the tyrosine metabolic pathway and the EGFR/MET signaling pathway. To summarize, the findings of the current study indicate that YFSJ is a prospective complementary treatment for Gef-resistant NSCLC.
MeSH term(s)	Rats ; Animals ; Carcinoma, Non-Small-Cell Lung/pathology ; Gefitinib/pharmacology ; Gefitinib/therapeutic use ; Lung Neoplasms/pathology ; Molecular Docking Simulation ; Chromatography, Liquid ; Prospective Studies ; ErbB Receptors/metabolism ; Drug Resistance, Neoplasm ; Tandem Mass Spectrometry ; Signal Transduction ; Cell Cycle ; Cell Line, Tumor ; Protein Kinase Inhibitors/pharmacology ; Cell Proliferation
Chemical Substances	Gefitinib (S65743JHBS) ; ErbB Receptors (EC 2.7.10.1) ; Protein Kinase Inhibitors
Language	English
Publishing date	2023-05-09
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2023.116566
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Article ; Online: Study on the Anti-demyelination Mechanism of Bu-Shen-Yi-Sui Capsule in the Central Nervous System Based on Network Pharmacology and Experimental Verification.

Zha, Zheng / Liu, Yi-Jiang / Liu, Si-Si / Zhang, Nan / Li, Jun-Ling / Qi, Fang / Jin, Liang-Yun / Xue, Bing / Yang, Tao / Fan, Yong-Ping / Zhao, Hui / Wang, Lei

Mediators of inflammation

2022 Volume 2022, Page(s) 9241261

Abstract: Methods: The potential active ingredients and corresponding potential targets of BSYS Capsule were obtained from the TCMSP, BATMAN-TCM, Swiss Target Prediction platform, and literature research. Disease targets of CNSD were explored through the ... ...

Abstract	Methods: The potential active ingredients and corresponding potential targets of BSYS Capsule were obtained from the TCMSP, BATMAN-TCM, Swiss Target Prediction platform, and literature research. Disease targets of CNSD were explored through the GeneCards and the DisGeNET databases. The matching targets of BSYS in CNSD were identified from a Venn diagram. The protein-protein interaction (PPI) network was constructed using bioinformatics methods. Gene Ontology (GO) function and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed to predict the mechanisms of BSYS. Furthermore, the neuroprotective effects of BSYS were evaluated using a cell model of hydrogen peroxide- (H Results: A total of 59 potential bioactive components of BSYS Capsule and 227 intersection targets were obtained. Topological analysis showed that AKT had the highest connectivity degrees in the PPI network. Enrichment analysis revealed that the targets of BSYS in the treatment of CNSD were the PI3K-Akt and MAPK signaling pathway, among other pathways. GO analysis results showed that the targets were associated with various biological processes, including apoptosis, reactive oxygen species metabolic process, and response to oxidative stress, among others. The experimental results demonstrated that BSYS drug-containing serum alleviated the H Conclusion: BSYS Capsule alleviated H
MeSH term(s)	Animals ; Central Nervous System ; Drugs, Chinese Herbal/therapeutic use ; Hydrogen Peroxide/pharmacology ; Medicine, Chinese Traditional/methods ; Network Pharmacology ; Phosphatidylinositol 3-Kinases ; Proto-Oncogene Proteins c-akt
Chemical Substances	Drugs, Chinese Herbal ; Hydrogen Peroxide (BBX060AN9V) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1)
Language	English
Publishing date	2022-07-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	1137605-3
ISSN	1466-1861 ; 0962-9351
ISSN (online)	1466-1861
ISSN	0962-9351
DOI	10.1155/2022/9241261
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Article ; Online: Bu-Fei Yi-Shen Granules Reduce Acute Exacerbations in Patients with GOLD 3-4 COPD: A Randomized Controlled Trial.

Yu, Xue-Qing / Di, Jia-Qi / Zhang, Wei / Wei, Geng-Shu / Ma, Zhan-Ping / Wu, Lei / Yu, Xue-Feng / Zhu, Hui-Zhi / Zhou, Miao / Feng, Cui-Ling / Feng, Ji-Hong / Fan, Ping / Li, Jian-Sheng / Yang, Jian-Ya

International journal of chronic obstructive pulmonary disease

2023 Volume 18, Page(s) 2439–2456

Abstract: ... of Bu-fei Yi-shen granules (BYGs) for COPD.: Patients and methods: We conducted a multicenter ...

Abstract	Purpose: Chronic obstructive pulmonary disease (COPD) is a disease characterized by frequent acute exacerbations (AEs), especially in severe and very severe cases. We aimed to evaluate the efficacy and safety of Bu-fei Yi-shen granules (BYGs) for COPD. Patients and methods: We conducted a multicenter, randomized, double-blinded, placebo-controlled trial of 348 COPD patients with GOLD 3-4 COPD. The patients were randomly assigned into experimental or control groups in a 1:1 ratio. Patients in the experimental group were prescribed BYG, while those in the control group were administered a placebo, orally, twice daily, with 5 days on and 2 days off per week for 52 weeks. The outcomes included AEs, pulmonary function, clinical signs and symptoms, dyspnea scores (mMRC), quality of life scores, and a 6-minute walk test (6MWT). Results: A total of 280 patients completed the trial, including 135 patients in the experimental group and 145 in the control group. Compared to the control group, significant differences were observed in frequencies of AEs (mean difference: -0.35; 95% CI: -0.61, -0.10; Conclusion: BYG, as compared to a placebo, could significantly reduce the frequencies of AEs and AE-related hospitalizations for GOLD 3-4 COPD patients. Clinical symptoms, treatment satisfaction, quality of life, and exercise capacity improved. There was no significant improvement in mortality and pulmonary function.
MeSH term(s)	Humans ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Quality of Life ; Lung ; Dyspnea ; Walking
Language	English
Publishing date	2023-11-06
Publishing country	New Zealand
Document type	Randomized Controlled Trial ; Multicenter Study ; Case Reports ; Clinical Trial
ZDB-ID	2212419-6
ISSN	1178-2005 ; 1176-9106
ISSN (online)	1178-2005
ISSN	1176-9106
DOI	10.2147/COPD.S413754
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Article ; Online: Mechanism of Action of Bu-Fei-Yi-Shen Formula in Treating Chronic Obstructive Pulmonary Disease Based on Network Pharmacology Analysis and Molecular Docking Validation.

Wu, Longchuan / Chen, Yu / Yi, Jiao / Zhuang, Yi / Cui, Lei / Ye, Chunhui

BioMed research international

2020 Volume 2020, Page(s) 9105972

Abstract: Objective: To explore the mechanism of action of Bu-Fei-Yi-Shen formula (BFYSF) in treating ...

Abstract	Objective: To explore the mechanism of action of Bu-Fei-Yi-Shen formula (BFYSF) in treating chronic obstructive pulmonary disease (COPD) based on network pharmacology analysis and molecular docking validation. Methods: First of all, the pharmacologically active ingredients and corresponding targets in BFYSF were mined by the Traditional Chinese Medicine Systems Pharmacology (TCMSP) database, the analysis platform, and literature review. Subsequently, the COPD-related targets (including the pathogenic targets and known therapeutic targets) were identified through the TTD, CTD, DisGeNet, and GeneCards databases. Thereafter, Cytoscape was employed to construct the candidate component-target network of BFYSF in the treatment of COPD. Moreover, the cytoHubba plug-in was utilized to calculate the topological parameters of nodes in the network; then, the core components and core targets of BFYSF in the treatment of COPD were extracted according to the degree value (greater than or equal to the median degree values for all nodes in the network) to construct the core network. Further, the Autodock vina software was adopted for molecular docking study on the core active ingredients and core targets, so as to verify the above-mentioned network pharmacology analysis results. Finally, the Omicshare database was applied in enrichment analysis of the biological functions of core targets and the involved signaling pathways. Results: In the core component-target network of BFYSF in treating COPD, there were 30 active ingredients and 37 core targets. Enrichment analysis suggested that these 37 core targets were mainly involved in the regulation of biological functions, such as response to biological and chemical stimuli, multiple cellular life processes, immunity, and metabolism. Besides, multiple pathways, including IL-17, Toll-like receptor (TLR), TNF, and HIF-1, played certain roles in the effect of BFYSF on treating COPD. Conclusion: BFYSF can treat COPD through the multicomponent, multitarget, and multipathway synergistic network, which provides basic data for intensively exploring the mechanism of action of BFYSF in treating COPD.
MeSH term(s)	Drugs, Chinese Herbal/pharmacology ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Interleukin-17/metabolism ; Medicine, Chinese Traditional ; Molecular Docking Simulation ; Protein Interaction Maps ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Signal Transduction ; Software ; Toll-Like Receptors/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Chemical Substances	Bu-Fei-Yi-Shen ; Drugs, Chinese Herbal ; HIF1A protein, human ; Hypoxia-Inducible Factor 1, alpha Subunit ; IL17A protein, human ; Interleukin-17 ; Toll-Like Receptors ; Tumor Necrosis Factor-alpha
Language	English
Publishing date	2020-11-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	2698540-8
ISSN	2314-6141 ; 2314-6133
ISSN (online)	2314-6141
ISSN	2314-6133
DOI	10.1155/2020/9105972
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Article ; Online: Tibetan medicine Ru-yi-Zhen-bao Pills exhibits anti-migraine effect through mediating PAG anti-nociceptive channel.

Luo, Ya Min / Ren, Xiao Qiao / Yang, Xue Qin / Song, Hui Rong / Li, Ran / Gao, Ming Hui / Li, Yi Ran / Zhou, Ran Ran / Ma, Lei / Zhang, Shu Jing / Dong, Ruan Juan / Ge, Dong Yu / Wang, Chun Guo / Ren, Qing Jia / Tao, Xiao Hua

Journal of ethnopharmacology

2019 Volume 249, Page(s) 112437

Abstract: ... As one of the marketed Tibetan drugs, Ru-yi-Zhen-bao Pills (RYZBP) have been clinically used to treat ... medium/low-dose groups (Ru-yi-Zhen-bao Pills; TH 1.00 g/kg, TM 0.50 g/kg and TL 0.25 g/kg). All rats were ...

Abstract	Ethnopharmacological relevance: Migraine is a disabling neurovascular disorder, which increases risk of cardiovascular events and is a social burden worldwide. The present first-line anti-migraine medications can cause overwhelming side-effects, of which one includes the onset of cardiovascular disease. As one of the marketed Tibetan drugs, Ru-yi-Zhen-bao Pills (RYZBP) have been clinically used to treat cardiovascular disorders and as anti-migraine medication. However, there is currently no research exploring the anti-migraine actions of RYZBP. Aim of the study: The current research was designed to assess the anti-migraine roles of RYZBP and explore the underlying mechanisms in a nitroglycerin (NTG)-induced migraine rat model trial. Materials and methods: 120 rats were randomly divided into the following six groups of 20 rats each: normal control group, model control group, positive control group, and RYZBP high/medium/low-dose groups (Ru-yi-Zhen-bao Pills; TH 1.00 g/kg, TM 0.50 g/kg and TL 0.25 g/kg). All rats were administered intragastrically for 7 consecutive days, which were subcutaneously injected with the NTG (10 mg/kg) after the last gavage (except in the normal control group). 3min after NTG treatment, 30 rats (5 rats from each group) were anesthetized and devoted to electroencephalogram(EEG) testing, which was used to evaluate the analgesic effect of RYZBP. One hour after NTG treatment, the rest of the 90 rats (15 rats from each group) were anesthetized and midbrain tissue sample was dissected. The dissection was then washed with physiological saline and collected. The histopathological changes in the periaqueductal gray(PAG) of 5 tissue samples were determined by aematoxylin-eosin (H&E) staining, as well as an estimation of substance P (SP) and neurokinin 1 receptor (NK1R) expression through immunohistochemically staining(IHC). Another 5 midbrain preparations were carried out to evaluate calcitonin gene-related peptide (CGRP), proenkephalin (PENK), SP, and cholecystokinin (CCK) expressions by real-time quantitative polymerase chain reaction (RT-qPCR). The rest of the 5 brainstem tissues were then used to measure CCK, CGRP, and opioid peptide receptor (DORR) levels by western blotting(WB). Results: In the EEG test, RYZBP (TM 0.50 g / kg) treatment transformed the EEG pain-wave of the NTG-induced migraine model rats in different time period. In the mechanism assay, compared with the model control group, RYZBP pretreatment reduced inflammatory cell infiltration, fibrosis and vacuolation of neuronal cells of PAG tissue seen by HE staining. IHC experiments further showed that RYZBPTM up-regulated SP expression levels and enhanced NK1R levels in the NTG-induced migraine rats (P < 0.05). Therapeutic administration of RYZBP also increased PENK mRNA expression and DORR protein level. Both RT-qPCR and western blotting trials indicated that RYZBP treatment significantly decreased CCK and CGRP expression levels (P < 0.01 or P < 0.05) in the NTG-induced migraine rats. Conclusions: RYZBP has the potential to be an effective anti-migraine treatment through suppressing the EEG pain-wave, increasing the levels of SP, PENK, DORR and reducing expression of CCK and CGRP. Mediating the PAG anti-nociceptive channel and inhibiting central sensitization were the two potential mechanisms, which offers further evidence for clinical therapy.
MeSH term(s)	Animals ; Calcitonin Gene-Related Peptide/metabolism ; Cholecystokinin/metabolism ; Disease Models, Animal ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use ; Electroencephalography ; Enkephalins/metabolism ; Humans ; Male ; Medicine, Tibetan Traditional/methods ; Migraine Disorders/chemically induced ; Migraine Disorders/diagnosis ; Migraine Disorders/drug therapy ; Migraine Disorders/pathology ; Nitroglycerin/toxicity ; Nociception/drug effects ; Periaqueductal Gray/drug effects ; Periaqueductal Gray/pathology ; Protein Precursors/metabolism ; Rats ; Rats, Sprague-Dawley ; Receptors, Opioid/metabolism
Chemical Substances	Drugs, Chinese Herbal ; Enkephalins ; Protein Precursors ; Receptors, Opioid ; proenkephalin ; Cholecystokinin (9011-97-6) ; Nitroglycerin (G59M7S0WS3) ; Calcitonin Gene-Related Peptide (JHB2QIZ69Z)
Language	English
Publishing date	2019-11-30
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2019.112437
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Article ; Online: Metallogeny of the Yi’nan Tongjing Au–Cu skarn deposit, Luxi district, North China Craton

Wen-Yan Cai / Zhao-Lu Zhang / Xiao Liu / Ji-Lei Gao / Ming Ma / Yadong Li / Ying-Xin Song / Zeng-Sheng Li

Frontiers in Earth Science, Vol

Perspective from in-suit trace elements, sulfur and lead isotopes of sulfides

2023 Volume 10

Abstract: ... hydrothermal processes. The Yi’nan Tongjing Au–Cu deposit is located in the central part of the Luxi district ... of shallow crustal material. The Yi’nan Tongjing Au–Cu skarn deposit was formed in the ... ...

Abstract	Gold–Cu skarn deposits are characterized by a diverse mineral assemblage, whose in-situ major/trace elements and isotope compositions can provide key constraints to the migration and enrichment of Au during hydrothermal processes. The Yi’nan Tongjing Au–Cu deposit is located in the central part of the Luxi district, and both skarn and Au–Cu ore bodies occur at the contact between the Early Cretaceous diorite porphyry and the Neoproterozoic to Cambrian carbonate rocks. Five stages of mineralization were identified: 1) early skarn (garnet–diopside–wollastonite); 2) late skarn (magnetite–epidote–actinolite±tremolite); 3) oxide (specularite–hematite); 4) sulfide (pyrite–chalcopyrite–sphalerite–quartz–chlorite); and 5) late quartz–calcite. The mineralization process in the Tongjing Au-Cu deposit was revealed by detailed scanning electron microscope-backscattered electron imaging, electron probe microanalysis, in-situ trace element, sulfur and lead isotope analysis. Magnetite is enriched in chalcophile elements (Cu, Zn, Pb), Co and Ni, probably due to hydrothermal overprint. The substitution of As and other elements in the formation of pyrite is conducive to the entry of Au into pyrite. The increase of Se and As contents in pyrite from stage IVa to IVb indicates that the temperature, salinity and oxygen fugacity of the ore-forming fluid decrease while the pH rises, resulting in the unloading of Au. The temperature of Au mineralization based on the Se content in pyrite does not exceed 300°C. Furthermore, V positively correlated with Ti and Ni/Cr ratios ≥1 in magnetite and most Co/Ni ratios in pyrite >10 all confirm their hydrothermal origins. The restricted sulfur (δ34SV-CDT = −0.5–1.2‰; mean = 0.4‰) and lead (206Pb/204Pb = 17.323–17.383; 207Pb/204Pb = 15.424–15.452; 208Pb/204Pb = 37.367–37.454) isotopic compositions suggest that the deep magma provided the primary mineralized material, accompanied by a relatively small amount of shallow crustal material. The Yi’nan Tongjing Au–Cu skarn deposit was formed in the ...
Keywords	in-situ trace elements analyses ; in-situ sulfur and lead isotopes ; Au precipitation mechanism ; Yi’nan Tongjing ; skarn deposit ; Luxi district ; Science ; Q
Subject code	550
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
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Book ; Online: Image encryption for Offshore wind power based on 2D-LCLM and Zhou Yi Eight Trigrams

Kou, Lei / Wu, Jinbo / Zhang, Fangfang / Ji, Peng / Ke, Wende / Wan, Junhe / Liu, Hailin / Li, Yang / Yuan, Quande

2023

Abstract: ... complex logistic mapping (2D-LCLM) and Zhou Yi Eight Trigrams. Firstly, the initial value of the 2D-LCLM ... rule is proposed from the Zhou Yi Eight Trigrams to obfuscate the pixel values and generate the round ...

Abstract	Offshore wind power is an important part of the new power system, due to the complex and changing situation at ocean, its normal operation and maintenance cannot be done without information such as images, therefore, it is especially important to transmit the correct image in the process of information transmission. In this paper, we propose a new encryption algorithm for offshore wind power based on two-dimensional lagged complex logistic mapping (2D-LCLM) and Zhou Yi Eight Trigrams. Firstly, the initial value of the 2D-LCLM is constructed by the Sha-256 to associate the 2D-LCLM with the plaintext. Secondly, a new encryption rule is proposed from the Zhou Yi Eight Trigrams to obfuscate the pixel values and generate the round key. Then, 2D-LCLM is combined with the Zigzag to form an S-box. Finally, the simulation experiment of the algorithm is accomplished. The experimental results demonstrate that the algorithm can resistant common attacks and has prefect encryption performance. Comment: accepted by Int. J. of Bio-Inspired Computation
Keywords	Computer Science - Cryptography and Security ; Computer Science - Computational Engineering ; Finance ; and Science ; Computer Science - Computer Vision and Pattern Recognition ; 68P25 ; E.3
Publishing date	2023-06-02
Publishing country	us
Document type	Book ; Online
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Article ; Online: Corrigendum to "Bu Shen Yi Sui capsule promotes remyelination correlating with Sema3A/ NRP-1, LIF/LIFR and Nkx6.2 in mice with experimental autoimmune encephalomyelitis" [J. Ethnopharmacol. 217 (2018) 36-48].

Zhao, Pei-Yuan / Wang, Yong-Qiang / Liu, Xi-Hong / Zhu, Ying-Jun / Zhao, Hui / Zhang, Qiu-Xia / Qi, Fang / Li, Jun-Ling / Zhang, Nan / Fan, Yong-Ping / Li, Kang-Ning / Zhao, Yuan-Yuan / Lei, Jian-Feng / Wang, Lei

Journal of ethnopharmacology

2023 Volume 318, Issue Pt A, Page(s) 116853

Language	English
Publishing date	2023-06-29
Publishing country	Ireland
Document type	Published Erratum
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2023.116853
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