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  1. Article ; Online: Pour une analyse du discours en géographie

    Louise de La Haye Saint Hilaire / Guillaume Schmitt / Christine Margetic

    Belgeo, Vol

    les paradigmes du foncier agricole dans deux agglomérations du Nord de la France

    2021  Volume 2

    Abstract: In a context of increasing attention to the demand for relocation, which calls on the production function of agricultural areas and their multifunctionality projected by citizens, farmland appears to be a subject invested from different angles, ... ...

    Abstract In a context of increasing attention to the demand for relocation, which calls on the production function of agricultural areas and their multifunctionality projected by citizens, farmland appears to be a subject invested from different angles, particularly by local public policies. This article aims to contribute to research on farmland by providing an analysis of the speech of institutional actors: Métropole Européenne de Lille and the conurbation of Douaisis (Nord). The work is also structured around a methodological objective: to propose a grid for analysing discourse in geography and urban planning. The article underlines both the interest of a qualitative approach and the contribution for geography to use of tools for the analysis and visualization of qualitative data.
    Keywords farmland ; discourse analysis ; food ; lexical approach ; Lille ; Douai (France) ; Geography (General) ; G1-922
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher Société Royale Belge de Géographie and the Belgian National Committee of Geography
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: COVID-19 Outbreak in France: Setup and Activities of a Mobile Extracorporeal Membrane Oxygenation Team During the First 3 Weeks.

    Haye, Guillaume / Fourdrain, Alex / Abou-Arab, Osama / Berna, Pascal / Mahjoub, Yazine

    Journal of cardiothoracic and vascular anesthesia

    2020  Volume 34, Issue 12, Page(s) 3493–3495

    MeSH term(s) COVID-19/epidemiology ; COVID-19/therapy ; Extracorporeal Membrane Oxygenation/instrumentation ; Extracorporeal Membrane Oxygenation/methods ; France/epidemiology ; Humans ; Pandemics ; Point-of-Care Systems
    Keywords covid19
    Language English
    Publishing date 2020-05-08
    Publishing country United States
    Document type Letter
    ZDB-ID 1067317-9
    ISSN 1532-8422 ; 1053-0770
    ISSN (online) 1532-8422
    ISSN 1053-0770
    DOI 10.1053/j.jvca.2020.05.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Prognostic value of right ventricular dilatation on computed tomography pulmonary angiogram for predicting adverse clinical events in severe COVID-19 pneumonia.

    Beyls, Christophe / Vial, Jeremie / Lefebvre, Thomas / Muller, Charlotte / Hanquiez, Thomas / Besserve, Patricia / Guilbart, Mathieu / Haye, Guillaume / Bernasinski, Michael / Huette, Pierre / Dupont, Hervé / Abou-Arab, Osama / Jounieaux, Vincent / Mahjoub, Yazine

    Frontiers in medicine

    2023  Volume 10, Page(s) 1213775

    Abstract: Background: Right ventricle dilatation (RVD) is a common complication of non-intubated COVID-19 pneumonia caused by pro-thrombotic pneumonitis, intra-pulmonary shunting, and pulmonary vascular dysfunction. In several pulmonary diseases, RVD is routinely ...

    Abstract Background: Right ventricle dilatation (RVD) is a common complication of non-intubated COVID-19 pneumonia caused by pro-thrombotic pneumonitis, intra-pulmonary shunting, and pulmonary vascular dysfunction. In several pulmonary diseases, RVD is routinely measured on computed tomography pulmonary angiogram (CTPA) by the right ventricle-to-left ventricle (LV) diameter ratio > 1 for predicting adverse events.
    Objective: The aim of the study was to evaluate the association between RVD and the occurrence of adverse events in a cohort of critically ill non-intubated COVID-19 patients.
    Methods: Between February 2020 and February 2022, non-intubated patients admitted to the Amiens University Hospital intensive care unit for COVID-19 pneumonia with CTPA performed within 48 h of admission were included. RVD was defined by an RV/LV diameter ratio greater than one measured on CTPA. The primary outcome was the occurrence of an adverse event (renal replacement therapy, extracorporeal membrane oxygenation, 30-day mortality after ICU admission).
    Results: Among 181 patients, 62% (
    Conclusion: Right ventricle (RV) dilatation assessed by RV/LV ratio was a common CTPA finding in non-intubated critical patients with COVID-19 pneumonia and was not associated with the occurrence of clinical adverse events.
    Language English
    Publishing date 2023-07-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1213775
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  4. Article: Almitrine for COVID-19 critically ill patients - a vascular therapy for a pulmonary vascular disease: Three case reports.

    Huette, Pierre / Abou Arab, Osama / Jounieaux, Vincent / Guilbart, Mathieu / Belhout, Mohamed / Haye, Guillaume / Dupont, Hervé / Beyls, Christophe / Mahjoub, Yazine

    World journal of clinical cases

    2021  Volume 9, Issue 14, Page(s) 3385–3393

    Abstract: Background: Several reports with clinical, histological and imaging data have observed the involvement of lung vascular function to explain the severe hypoxemia in coronavirus disease 2019 (COVID-19) patients. It has been hypothesized that an increased ... ...

    Abstract Background: Several reports with clinical, histological and imaging data have observed the involvement of lung vascular function to explain the severe hypoxemia in coronavirus disease 2019 (COVID-19) patients. It has been hypothesized that an increased pulmonary blood flow associated with an impairment of hypoxic pulmonary vasoconstriction is responsible for an intrapulmonary shunt. COVID-19 may lead to refractory hypoxemia (PaO
    Case summary: We report our experience with three patients with refractory hypoxemia treated with almitrine to enhance oxygenation. Low dose almitrine (Vectarion
    Conclusion: Almitrine may be effective and safe to enhance oxygenation in coronavirus disease 2019 patients. Further controlled studies are required.
    Language English
    Publishing date 2021-05-13
    Publishing country United States
    Document type Case Reports
    ISSN 2307-8960
    ISSN 2307-8960
    DOI 10.12998/wjcc.v9.i14.3385
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Preload Dependency of 2D Right Ventricle Speckle Tracking Echocardiography Parameters in Healthy Volunteers: A Prospective Pilot Study.

    Beyls, Christophe / Bohbot, Yohann / Caboche, Matthieu / Huette, Pierre / Haye, Guillaume / Dupont, Hervé / Mahjoub, Yazine / Osama, Abou-Arab

    Journal of clinical medicine

    2021  Volume 11, Issue 1

    Abstract: 1) Background: Right ventricular (RV) strain parameters derived from the analysis of the tricuspid annular displacement (TAD) are emergent two-dimensional speckle tracking echocardiography (2D-STE) parameter used for the quantitative assessment of RV ... ...

    Abstract (1) Background: Right ventricular (RV) strain parameters derived from the analysis of the tricuspid annular displacement (TAD) are emergent two-dimensional speckle tracking echocardiography (2D-STE) parameter used for the quantitative assessment of RV systolic function. Few data are available regarding 2D-STE parameters and their dependency on RV preload. Our aim was to evaluate the effect of an acute change in RV preload on 2D-STE parameters in healthy volunteers. (2) Methods: Acute modification of RV preload was performed by a fluid challenge (FC): an infusion of 500 mL of 0.9% sodium chloride was given over 5 min in supine position. Preload dependency (responder group) was confirmed by a stroke volume increase of at least 10% measured by echocardiography. (3) Results: Among 32 healthy volunteers, 19 (59%) subjects were classified as non-responders and 13 (41%) as responders. In the responder group, the tricuspid annular plane systolic excursion (TAPSE) significantly increased (20 (20-23.5) mm to 24 (20.5-26.5) mm;
    Language English
    Publishing date 2021-12-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11010019
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  6. Article ; Online: Preload Dependency of 2D Right Ventricle Speckle Tracking Echocardiography Parameters in Healthy Volunteers

    Christophe Beyls / Yohann Bohbot / Matthieu Caboche / Pierre Huette / Guillaume Haye / Hervé Dupont / Yazine Mahjoub / Abou-Arab Osama

    Journal of Clinical Medicine, Vol 11, Iss 19, p

    A Prospective Pilot Study

    2022  Volume 19

    Abstract: 1) Background: Right ventricular (RV) strain parameters derived from the analysis of the tricuspid annular displacement (TAD) are emergent two-dimensional speckle tracking echocardiography (2D-STE) parameter used for the quantitative assessment of RV ... ...

    Abstract (1) Background: Right ventricular (RV) strain parameters derived from the analysis of the tricuspid annular displacement (TAD) are emergent two-dimensional speckle tracking echocardiography (2D-STE) parameter used for the quantitative assessment of RV systolic function. Few data are available regarding 2D-STE parameters and their dependency on RV preload. Our aim was to evaluate the effect of an acute change in RV preload on 2D-STE parameters in healthy volunteers. (2) Methods: Acute modification of RV preload was performed by a fluid challenge (FC): an infusion of 500 mL of 0.9% sodium chloride was given over 5 min in supine position. Preload dependency (responder group) was confirmed by a stroke volume increase of at least 10% measured by echocardiography. (3) Results: Among 32 healthy volunteers, 19 (59%) subjects were classified as non-responders and 13 (41%) as responders. In the responder group, the tricuspid annular plane systolic excursion (TAPSE) significantly increased (20 (20–23.5) mm to 24 (20.5–26.5) mm; p = 0.018), while RV strain parameters significantly decreased after FC: −23.5 ((−22.3)–(−27.3))% to −25 ((−24)–(29.6))%; p = 0.03) for RV free wall longitudinal strain and −22.8 ((−20.4)–(−30.7))% to −23.7 ((−21.2)–(−27))%; p = 0.02) for RV four-chamber longitudinal strain. 2D-STE parameters derived from the TAD analysis were not influenced by the FC (all p > 0.05). (4) Conclusions: In young, healthy volunteers, RV strain parameters and TAPSE are preload dependent, while TAD parameters were not. The loading conditions must be accounted for when evaluating RV systolic function by 2D-STE parameters.
    Keywords right ventricle ; speckle tracking ; strain ; preload ; fluid challenge ; Medicine ; R
    Language English
    Publishing date 2022-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Effect of the oXiris membrane on microcirculation after cardiac surgery under cardiopulmonary bypass: study protocol for a randomised controlled trial (OXICARD Study).

    Abou-Arab, Osama / Huette, Pierre / Haye, Guillaume / Guilbart, Mathieu / Touati, Gilles / Diouf, Momar / Beyls, Christophe / Dupont, Herve / Mahjoub, Yazine

    BMJ open

    2021  Volume 11, Issue 7, Page(s) e044424

    Abstract: Introduction: Cytokine storm and endotoxin release during cardiac surgery with cardiopulmonary bypass (CPB) have been related to vasoplegic shock and organ dysfunction. We hypothesised that early (during CPB) cytokine adsorption with oXiris membrane for ...

    Abstract Introduction: Cytokine storm and endotoxin release during cardiac surgery with cardiopulmonary bypass (CPB) have been related to vasoplegic shock and organ dysfunction. We hypothesised that early (during CPB) cytokine adsorption with oXiris membrane for patients at high risk of inflammatory syndrome following cardiac surgery may improve microcirculation, endothelial function and outcomes.
    Methods and analysis: The Oxicard trial is a prospective, monocentric trial, randomising 70 patients scheduled for cardiac surgery. The inclusion criterion is patients aged more than 18 years old undergoing elective cardiac surgery under CPB with an expected CPB time >90 min (double valve replacement or valve replacement plus coronary arterial bypass graft). Patients will be allocated to the intervention group (n=35) or the control group (n=35). In the intervention group, oXiris membrane will be used on the Prismaflex device (Baxter) at blood pump flow of 450 mL/min during cardiac surgery under CPB. In the control group, cardiac surgery under CPB will be conducted as usual without oXiris membrane. An intention-to-treat analysis will be performed. The primary endpoint will be the microcirculatory flow index measured by sublingual microcirculation device at day 1 following cardiac surgery. The secondary endpoints will be other microcirculation variables at CPB end, 6 hours after CPB, at day 1 and at day 2. We also aim to evaluate the occurrence of major cardiovascular and cerebral events (eg, myocardial infarction, stroke, ischaemic mesenteric, resuscitated cardiac arrest, acute kidney injury) within the first 30 days. Cumulative catecholamine use, intensive care unit length of stay, endothelium glycocalyx shedding parameters (syndecan-1, heparan-sulfate and hyaluronic acid), inflammatory cytokines (tumour necrosis factor (TNF) alpha, interleukin 1 (IL1) beta, IL 10, IL 6, lipopolysaccharide, endothelin) and endothelial permeability biomarkers (angiopoietin 1, angiopoietin 2, Tie2 soluble receptor and Vascular Endothelial Growth Factor (VEGF) will also be evaluated.
    Ethics and dissemination: Ethical approval has been obtained from the Institutional Review Board of the University Hospital of Amiens (registration number ID RDB: 2019-A02437-50 in February 2020). Results of the study will be disseminated via peer-reviewed publications and presentations at national and international conferences.
    Trial registration number: NCT04201119.
    MeSH term(s) Adolescent ; Cardiac Surgical Procedures/adverse effects ; Cardiopulmonary Bypass/adverse effects ; Humans ; Microcirculation ; Prospective Studies ; Randomized Controlled Trials as Topic ; Vascular Endothelial Growth Factor A
    Chemical Substances Vascular Endothelial Growth Factor A
    Language English
    Publishing date 2021-07-09
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2020-044424
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  8. Article: Iatrogenic Acute Type A Aortic Dissection following Elective Cardiopulmonary Bypass.

    Huette, Pierre / Beyls, Christophe / Guilbart, Mathieu / Haye, Guillaume / Vial, Jérémie / Touati, Gilles / Mahjoub, Yazine / Abou-Arab, Osama

    Aorta (Stamford, Conn.)

    2020  Volume 8, Issue 5, Page(s) 155–158

    Abstract: We report a 62-year-old woman who was scheduled for an elective Tirone David valve sparing aortic root replacement under cardiopulmonary bypass. Within the next few hours, the patient developed bilateral acute ischemia of both lower limbs. A thoracic and ...

    Abstract We report a 62-year-old woman who was scheduled for an elective Tirone David valve sparing aortic root replacement under cardiopulmonary bypass. Within the next few hours, the patient developed bilateral acute ischemia of both lower limbs. A thoracic and abdominopelvic computed tomography scan showed acute Type A aortic dissection with a perforation at the brachiocephalic arterial trunk and a complete malperfusion of the inferior mesenteric and iliac arteries.
    Language English
    Publishing date 2020-12-23
    Publishing country Germany
    Document type Journal Article
    ISSN 2325-4637
    ISSN 2325-4637
    DOI 10.1055/s-0040-1715124
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  9. Article: COVID-19 Outbreak in France: Setup and Activities of a Mobile Extracorporeal Membrane Oxygenation Team During the First 3 Weeks

    Haye, Guillaume / Fourdrain, Alex / Abou-Arab, Osama / Berna, Pascal / Mahjoub, Yazine

    J. cardiothoracic vasc. anest

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32457006
    Database COVID19

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  10. Article ; Online: COVID-19 outbreak in France: Setup and activities of a mobile Extra Corporeal Membrane Oxygenation (ECMO) team during the first 3 weeks

    Haye, Guillaume / Fourdrain, Alex / Abou-Arab, Osama / Berna, Pascal / Mahjoub, Yazine

    J Cardiothorac Vasc Anesth

    Keywords covid19
    Publisher PMC
    Document type Article ; Online
    DOI 10.1053/j.jvca.2020.05.004
    Database COVID19

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