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  1. Article: Diagnostic value of synovial fluid adenosine deaminase level in tuberculous arthritis.

    Sohn, Kyung Mok

    JPMA. The Journal of the Pakistan Medical Association

    2021  Volume 71, Issue 4, Page(s) 1246–1248

    Abstract: Although body fluid adenosine deaminase (ADA) level is useful for diagnosing tuberculosis but little is known about joint fluid ADA level in tuberculous (TB) arthritis. This study aimed to evaluate the diagnostic value of synovial fluid ADA (SF-ADA) in ... ...

    Abstract Although body fluid adenosine deaminase (ADA) level is useful for diagnosing tuberculosis but little is known about joint fluid ADA level in tuberculous (TB) arthritis. This study aimed to evaluate the diagnostic value of synovial fluid ADA (SF-ADA) in TB arthritis. Of 43 patients enrolled, nine had confirmed TB arthritis. Fourteen had non-TB septic arthritis, and 20 patients had non-infectious etiologies. The SF-ADA levels were significantly elevated in patients with TB arthritis compared to those with non-infectious origin (P <0.05). All SF-ADA levels were 76 ≥ U/L in TB arthritis and < 60 U/L in non-infectious synovial fluid. The ADA was not different between TB arthritis and non-TB septic arthritis (P = 0.87). The possibility of identifying synovial fluid with an ADA under 60-76 U/L of tuberculous etiology may be very low. In addition, an SF-ADA >76 U/L with negative ordinary bacterial culture results is highly suspicious for TB arthritis.
    MeSH term(s) Adenosine Deaminase ; Arthritis, Infectious/diagnosis ; Humans ; Pleural Effusion ; Sensitivity and Specificity ; Synovial Fluid ; Tuberculosis, Osteoarticular
    Chemical Substances Adenosine Deaminase (EC 3.5.4.4)
    Language English
    Publishing date 2021-06-14
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    DOI 10.47391/JPMA.708
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Alleged debridement with maggots.

    Sohn, Kyung Mok / Lee, Jooyeon

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2020  Volume 95, Page(s) 13–14

    Language English
    Publishing date 2020-03-31
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2020.03.048
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  3. Article: Methicillin Resistance Increased the Risk of Treatment Failure in Native Joint Septic Arthritis Caused by

    Kim, Jungok / Park, So Yeon / Sohn, Kyung Mok / Kim, Bomi / Joo, Eun-Jeong

    Antibiotics (Basel, Switzerland)

    2023  Volume 12, Issue 11

    Abstract: This study aimed to compare clinical characteristics and outcomes in patients with native joint septic arthritis (NJSA) due to methicillin- ... ...

    Abstract This study aimed to compare clinical characteristics and outcomes in patients with native joint septic arthritis (NJSA) due to methicillin-resistant
    Language English
    Publishing date 2023-11-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12111628
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  4. Article: Administering Antibiotics for Less Than Four Weeks Increases the Risk of Relapse in Culture-Positive Septic Arthritis of Native Joints.

    Joo, Eun-Jeong / Kim, Bomi / Sohn, Kyung Mok / Kym, Sungmin / Kim, Jungok

    Journal of clinical medicine

    2023  Volume 12, Issue 21

    Abstract: 1) Objectives: This study investigated the optimal duration of antibiotic therapy and determined the risk factors associated with relapse in patients with culture-proven septic arthritis of native joints. (2) Methods: A retrospective review was ... ...

    Abstract (1) Objectives: This study investigated the optimal duration of antibiotic therapy and determined the risk factors associated with relapse in patients with culture-proven septic arthritis of native joints. (2) Methods: A retrospective review was conducted on patients aged ≥18 years diagnosed with native joint septic arthritis, with bacteria isolated from joints and/or blood. The exclusion criteria were prosthetic joint infections and cases with no identified microorganisms. The outcomes were assessed in the remission and relapse groups. (3) Results: Among 479 patients with native joint septic arthritis, 137 met the inclusion criteria, with a median follow-up duration of 2.7 years. The relapse rate was 9.5%, which mainly occurred within 30 days after antibiotic treatment completion. Compared with the remission group, the relapse group showed a significantly higher proportion of cases that received antibiotic therapy for ≤ 4 weeks (4.8% vs. 46.2%,
    Language English
    Publishing date 2023-10-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12216808
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  5. Article: Corrigendum: Differential association of viral dynamics with disease severity depending on patients' age group in COVID-19.

    Kim, Yuri / Cheon, Shinhyea / Jeong, Hyeongseok / Park, Uni / Ha, Na-Young / Lee, Jooyeon / Sohn, Kyung Mok / Kim, Yeon-Sook / Cho, Nam-Hyuk

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1178685

    Abstract: This corrects the article DOI: 10.3389/fmicb.2021.712260.]. ...

    Abstract [This corrects the article DOI: 10.3389/fmicb.2021.712260.].
    Language English
    Publishing date 2023-03-14
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1178685
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  6. Article ; Online: Administering Antibiotics for Less Than Four Weeks Increases the Risk of Relapse in Culture-Positive Septic Arthritis of Native Joints

    Eun-Jeong Joo / Bomi Kim / Kyung Mok Sohn / Sungmin Kym / Jungok Kim

    Journal of Clinical Medicine, Vol 12, Iss 21, p

    2023  Volume 6808

    Abstract: 1) Objectives: This study investigated the optimal duration of antibiotic therapy and determined the risk factors associated with relapse in patients with culture-proven septic arthritis of native joints. (2) Methods: A retrospective review was ... ...

    Abstract (1) Objectives: This study investigated the optimal duration of antibiotic therapy and determined the risk factors associated with relapse in patients with culture-proven septic arthritis of native joints. (2) Methods: A retrospective review was conducted on patients aged ≥18 years diagnosed with native joint septic arthritis, with bacteria isolated from joints and/or blood. The exclusion criteria were prosthetic joint infections and cases with no identified microorganisms. The outcomes were assessed in the remission and relapse groups. (3) Results: Among 479 patients with native joint septic arthritis, 137 met the inclusion criteria, with a median follow-up duration of 2.7 years. The relapse rate was 9.5%, which mainly occurred within 30 days after antibiotic treatment completion. Compared with the remission group, the relapse group showed a significantly higher proportion of cases that received antibiotic therapy for ≤ 4 weeks (4.8% vs. 46.2%, p < 0.001), synovial fluid white blood cell (WBC) counts ≥150 × 10 3 /mm 3 (25.3% vs. 60.0%, p = 0.030), acute kidney injury (19.2% vs. 50%, p = 0.024), and extended-spectrum beta-lactamases-producing Enterobacteriaceae (0.8 vs. 15.4%, p = 0.024). Independent risk factors for relapse were determined as antibiotic therapy duration of ≤ 4 weeks (odds ratio (OR), 25.47; 95% confidence interval (CI), 1.57–412.33; p = 0.023) and synovial fluid WBC counts ≥150 × 10 3 /mm 3 (OR, 17.46; 95% CI, 1.74–175.62; p = 0.015). (4) Conclusions: Patients with native joint septic arthritis require vigilant monitoring for relapse, particularly when treated with antibiotic regimens administered for less than four weeks or when synovial aspirates exhibit elevated WBC counts at diagnosis.
    Keywords arthritis ; infectious ; septic arthritis ; native joint septic arthritis ; bone and joint infections ; antibiotic duration ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Two Fatal Cases of Stress-induced Cardiomyopathy in COVID-19 Patients.

    Park, Jae Hyeong / Moon, Jae Young / Sohn, Kyung Mok / Kim, Yeon Sook

    Journal of cardiovascular imaging

    2020  Volume 28, Issue 4, Page(s) 300–303

    Keywords covid19
    Language English
    Publishing date 2020-10-21
    Publishing country Korea (South)
    Document type Case Reports
    ZDB-ID 3020035-0
    ISSN 2586-7296 ; 2586-7210
    ISSN (online) 2586-7296
    ISSN 2586-7210
    DOI 10.4250/jcvi.2020.0125
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  8. Article: Guidelines for Infection Control and Burnout Prevention in Healthcare Workers Responding to COVID-19.

    Park, Se Yoon / Cheong, Hae Suk / Kwon, Ki Tae / Sohn, Kyung Mok / Heo, Sang Taek / Lee, Shinwon / Chung, Un Sun / Lee, So Hee

    Infection & chemotherapy

    2023  Volume 55, Issue 1, Page(s) 150–165

    Abstract: During the coronavirus disease 2019 (COVID-19) pandemic, frontline healthcare workers (HCWs) suffered more distress from the possibility of contracting the virus, quarantine, social stigma, and prejudice against their families. Many studies have ... ...

    Abstract During the coronavirus disease 2019 (COVID-19) pandemic, frontline healthcare workers (HCWs) suffered more distress from the possibility of contracting the virus, quarantine, social stigma, and prejudice against their families. Many studies have investigated the impact of the pandemic on HCWs; however, studies or guidelines presenting strategies to overcome these challenges are lacking. As part of a 2020 research project supported by the Ministry of Health and Welfare, titled "Health impact assessment of healthcare workers undertaking coronavirus disease 2019 treatment and management in Korea: Identifying problems and researching effective solutions" (HC20C0003), we created guidelines to respond to serious problems posed by infection control. and burnout among HCWs during COVID-19 response measures throughout the extended pandemic period. We formulated the guidelines by means of a systematic review and collated them with the latest literature. The guidelines will highlight the gravity and impact of infection control and burnout among HCWs responding to COVID-19 and include potential prevention strategies, and they can be used as a reference in the event of another emerging infectious disease outbreak in the future.
    Language English
    Publishing date 2023-04-04
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 2573798-3
    ISSN 2093-2340
    ISSN 2093-2340
    DOI 10.3947/ic.2022.0164
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6842: Show issues Location:
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  9. Article ; Online: Improvement in Health-Related Quality of Life Following Antibiotic Treatment in Nontuberculous Mycobacterial Pulmonary Disease: Initial Analysis of the NTM-KOREA Cohort.

    Kwak, Nakwon / Henkle, Emily / Hwang, Hyeontaek / Jeon, Doosoo / Jhun, Byung Woo / Jo, Kyung-Wook / Kang, Young Ae / Kim, Hyung-Jun / Kim, Joong-Yub / Kim, Young Ran / Kwon, Yong-Soo / Lee, Jae Ho / Mok, Jeongha / Park, Youngmok / Shim, Tae Sun / Sohn, Hojoon / Whang, Jake / Yim, Jae-Joon

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2024  

    Abstract: Background: Improving health-related quality of life (HRQOL) has emerged as a priority in the management of nontuberculous mycobacterial pulmonary disease (NTM-PD). We aimed to evaluate HRQOL and its changes after 6 months' treatment in patients with ... ...

    Abstract Background: Improving health-related quality of life (HRQOL) has emerged as a priority in the management of nontuberculous mycobacterial pulmonary disease (NTM-PD). We aimed to evaluate HRQOL and its changes after 6 months' treatment in patients with NTM-PD.
    Methods: The NTM-KOREA is a nationwide prospective cohort enrolling patients initiating treatment for NTM-PD in 8 institutions across South Korea. We conducted the Quality of Life-Bronchiectasis (QOL-B) at 6-month intervals and evaluated baseline scores (higher scores indicate better quality of life) and changes after 6 months' treatment. Multivariate logistic regression was performed to identify factors associated with improvement in the QOL-B physical functioning and respiratory symptoms domains.
    Results: Between February 2022 and August 2023, 411 patients were included in the analysis. Baseline scores (95% confidence interval [CI]) for physical functioning and respiratory symptoms were 66.7 (46.7-86.7) and 81.5 (70.4-92.6), respectively. Among 228 patients who completed the QOL-B after 6 months' treatment, improvements in physical functioning and respiratory symptoms were observed in 61 (26.8%) and 71 (31.1%) patients, respectively. A lower score (adjusted odds ratio; 95% CI) for physical functioning (0.93; 0.91-0.96) and respiratory symptoms (0.92; 0.89-0.95) at treatment initiation was associated with a greater likelihood of physical functioning and respiratory symptom improvement, respectively; achieving culture conversion was not associated with improvement in physical functioning (0.62; 0.28-1.39) or respiratory symptoms (1.30; 0.62-2.74).
    Conclusions: After 6 months of antibiotic treatment for NTM-PD, HRQOL improved in almost one-third, especially in patients with severe initial symptoms, regardless of culture conversion.
    Clinical trials registration: ClinicalTrials.gov identifier: NCT03934034.
    Language English
    Publishing date 2024-04-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciae131
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  10. Article: Higher Risk for All-cause Mortality of

    Kim, Yeon Sook / Kim, Jungok / Cheon, Shinhye / Sohn, Kyung Mok

    Infection & chemotherapy

    2020  Volume 52, Issue 1, Page(s) 82–92

    Abstract: Background: Staphylococcus aureus: Materials and methods: We conducted a retrospective study on the patients with SAB hospitalized in a tertiary care center in Korea between March 2014 and December 2018. Kaplan-Meier analysis was performed to compare ...

    Abstract Background: Staphylococcus aureus
    Materials and methods: We conducted a retrospective study on the patients with SAB hospitalized in a tertiary care center in Korea between March 2014 and December 2018. Kaplan-Meier analysis was performed to compare all-cause mortality following SAB among patients with non-dialysis dependent CKD (ND-CKD), those receiving dialysis, and those without CKD (non-CKD). The predictors of mortality among CKD patients were analyzed by Cox proportional hazards regression.
    Results: As a total, 278 SAB of 43 ND-CKD (31 males), 58 dialysis (39 males), and 177 non-CKD (112 males) patients were included. The 30-day mortality was 39.5% in ND-CKD, 27.6% in dialysis, and 7.9% in non-CKD patients. The hazard ratio of all-cause mortality following SAB in ND-CKD was 2.335 (95% confidence interval, 1.203 - 4.531;
    Conclusion: ND-CKD patients demonstrated poor outcome following SAB and administration of appropriate antibiotics within 48 h could reduce the risk for mortality.
    Language English
    Publishing date 2020-02-20
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2573798-3
    ISSN 2093-2340
    ISSN 2093-2340
    DOI 10.3947/ic.2020.52.1.82
    Database MEDical Literature Analysis and Retrieval System OnLINE

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