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  1. Book ; Online ; E-Book: Clinical Manual of Psychopharmacology in the Medically Ill

    Ferrando, Stephen J.

    2023  

    Abstract: With 19 new psychiatric drugs, 19 new forms of previously available drugs, and new medical agents, this third editionl has been updated to account for both medical and psychiatric drugs that have become available since the second edition, as well as ... ...

    Abstract With 19 new psychiatric drugs, 19 new forms of previously available drugs, and new medical agents, this third editionl has been updated to account for both medical and psychiatric drugs that have become available since the second edition, as well as recent relevant randomized controlled trials, systematic reviews, and meta-analyses.
    Keywords Psychology, Pathological ; Mental illness
    Subject code 616.89
    Language English
    Size 1 online resource (896 pages)
    Edition 3rd ed.
    Publisher American Psychiatric Association Publishing
    Publishing place Washington, D.C
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-61537-514-7 ; 978-1-61537-514-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Clinical manual of psychopharmacology in the medically ill

    Ferrando, Stephen J.

    2010  

    Title variant Psychopharmacology in the medically ill
    Author's details ed. by Stephen J. Ferrando
    Keywords Psychotropic Drugs / adverse effects ; Psychotropic Drugs / pharmacokinetics ; Comorbidity ; Drug Interactions
    Language English
    Size XXX, 610 S.
    Edition 1. ed.
    Publisher American Psychiatric Publ
    Publishing place Washington, DC u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT016629736
    ISBN 978-1-58562-367-9 ; 1-58562-367-9
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2010 A 6400 order for loan Magazin

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  3. Article ; Online: No Difference in Neuropsychiatric PASC Between Vaccinated and Unvaccinated Patients: Further Insights From a Cross-Sectional Study.

    Saperia, Corey / Lynch, Sean / Dornbush, Rhea / Ferrando, Stephen J

    Journal of the Academy of Consultation-Liaison Psychiatry

    2023  Volume 64, Issue 4, Page(s) 409–411

    MeSH term(s) Humans ; Cross-Sectional Studies ; Vaccination/adverse effects
    Language English
    Publishing date 2023-07-20
    Publishing country Netherlands
    Document type Letter
    ISSN 2667-2960
    ISSN (online) 2667-2960
    DOI 10.1016/j.jaclp.2023.04.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Anxiety and posttraumatic stress in post-acute sequelae of COVID-19: prevalence, characteristics, comorbidity, and clinical correlates.

    Ferrando, Stephen J / Lynch, Sean / Ferrando, Nicole / Dornbush, Rhea / Shahar, Sivan / Klepacz, Lidia

    Frontiers in psychiatry

    2023  Volume 14, Page(s) 1160852

    Abstract: Background: Anxiety and post-traumatic stress symptoms have been reported in association with acute and post-acute sequelae of COVID-19 (PASC).: Purpose: This study aimed to document the cross-sectional prevalence, characteristics and clinical ... ...

    Abstract Background: Anxiety and post-traumatic stress symptoms have been reported in association with acute and post-acute sequelae of COVID-19 (PASC).
    Purpose: This study aimed to document the cross-sectional prevalence, characteristics and clinical correlates of anxiety and post-traumatic stress in a study of neuropsychiatric sequelae of COVID-19.
    Method: 75 participants recruited from a post-COVID-19 recovery program and the community were assessed for sociodemographic, medical, psychiatric, and neurocognitive symptoms and performance. The generalized anxiety questionnaire-7 (GAD-7) and post-traumatic stress disorder questionnaire for DSM5 (PCL5) were utilized to measure anxiety and PTSD symptoms. Established cutoff scoring for the GAD-7 and algorithm-based scoring of the PCL5 were utilized to determine clinically significant anxiety symptoms and PTSD, respectively.
    Results: The cohort was 71% female, 36% ethnic minority, with the main age of 43.5 years, 80% employment, 40% with the prior psychiatric treatment history and 2/3 seeking post-COVID care for PASC. Clinically significant anxiety symptoms were found in 31% and PTSD was found in 29% of the cohort. Nervousness and excessive worry were the most prominent anxiety symptoms, while changes in mood/cognition and avoidance were most frequent in PTSD. There was a high degree of comorbidity between clinically significant anxiety symptoms, PTSD, depression and fatigue. In logistic regression, acute COVID illness severity, prior psychiatric history, and memory complaints (but not objective neuropsychological performance) predicted clinically significant anxiety symptoms and/or PTSD.
    Conclusion: Clinically significant anxiety and PTSD are found in approximately 1 of 3 individuals after COVID-19 infection. They are highly comorbid with each other as well as with depression and fatigue. All patients seeking care for PASC should be screened for these neuropsychiatric complications. Symptoms of worry, nervousness, subjective changes in mood, and cognition as well as behavioral avoidance are particularly important targets of clinical intervention.
    Language English
    Publishing date 2023-06-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1160852
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: When Did the Empathy Die?: Examining the Correlation Between Length of Medical Training and Level of Empathy.

    Dinoff, Adam / Lynch, Sean / Hameed, Azeb Shahul / Koestler, Jennifer / Ferrando, Stephen J / Klepacz, Lidia

    Medical science educator

    2023  Volume 33, Issue 2, Page(s) 489–497

    Abstract: Purpose: Empathy is an important skill for physicians as it can lead to improved patient outcomes and satisfaction. This study assessed self-reported empathy by medical students across all four years of medical school and potential differences in ... ...

    Abstract Purpose: Empathy is an important skill for physicians as it can lead to improved patient outcomes and satisfaction. This study assessed self-reported empathy by medical students across all four years of medical school and potential differences in empathy across students interested in different subspecialties.
    Method: All medical students enrolled at New York Medical College in August 2020 were invited to participate in this study. Participants completed the student version of the Jefferson Scale of Empathy.
    Results: A total of 179 medical students participated. Mean empathy score in fourth-year students was significantly lower than that in first-year students. Mean empathy score was greatest among students interested in Pediatrics and was greater in participants who identified as women.
    Conclusions: Self-reported empathy may be lower in upper-year medical students when compared to lower-year students. The potential reasons for lower empathy in the later years of training are discussed. A systematic curriculum for teaching and maintaining empathy should be developed and uniformly implemented across medical schools to combat a potential decline in empathy.
    Language English
    Publishing date 2023-03-17
    Publishing country United States
    Document type Journal Article
    ISSN 2156-8650
    ISSN (online) 2156-8650
    DOI 10.1007/s40670-023-01768-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Change in Neuropsychological Test Performance Seen in a Longitudinal Study of Patients With Post-acute Sequelae of COVID-19: A 6-Month Follow-up Study.

    Lynch, Sean T / Dornbush, Rhea / Shahar, Sivan / Mansour, Rayah / Klepacz, Lidia / Primavera, Louis H / Ferrando, Stephen J

    Journal of the Academy of Consultation-Liaison Psychiatry

    2024  

    Abstract: Background: Post-acute sequelae of COVID-19 may include physical, psychiatric, and neurocognitive symptoms. Few studies of cognitive symptoms have been longitudinal, with many following participants briefly after infection and relying on subjective ... ...

    Abstract Background: Post-acute sequelae of COVID-19 may include physical, psychiatric, and neurocognitive symptoms. Few studies of cognitive symptoms have been longitudinal, with many following participants briefly after infection and relying on subjective complaints, screening instruments, or computerized testing. This group previously reported diminished neuropsychological (NP) test performance in over half of 60 individuals tested in-person 7 months post-COVID-19, particularly those seeking care for cognitive complaints. The current study describes the initial and 6-month follow-up results of an expanded cohort of 75 participants.
    Objective: To measure longitudinal changes in neuropsychological test performance, as well as medical and psychiatric changes, post-COVID-19.
    Methods: Participants underwent NP, psychiatric, and medical assessments approximately 7 months after acute COVID-19 infection. Sixty-three (84%) returned approximately 6 months later for repeat evaluation.
    Results: At the initial visit, 29 (38.7%) met criteria for low NP performance, and 16 (21.3%) met criteria for extremely low NP performance. At 6-month follow-up, several NP domains that were significantly below normative values at the initial visit were no longer abnormal, with the exception of language. Only measures of delayed memory and fatigue showed significant improvements between the 2 time points.
    Conclusions: A substantial proportion of individuals recovered from acute COVID-19 infection have persistent neuropsychiatric symptoms over 1 year after infection. While the overall sample in this study showed some improvement in NP test performance relative to norms, only fatigue and delayed memory improved significantly between times 1 and 2. No individual declined in NP test performance, though relatively few individuals made significant clinical improvement, indicating the need for serial neuropsychiatric assessment and treatment supports. Longitudinal follow-up of this cohort is in progress.
    Language English
    Publishing date 2024-01-01
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2667-2960
    ISSN (online) 2667-2960
    DOI 10.1016/j.jaclp.2023.12.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Frequency, Characteristics, and Correlates of Cognitive Complaints in a Cohort of Individuals with Post-Acute Sequelae of COVID-19.

    Muschel, Cayla / Lynch, Sean T / Dornbush, Rhea / Klepacz, Lidia / Shahar, Sivan / Ferrando, Stephen J

    Brain sciences

    2023  Volume 14, Issue 1

    Abstract: Background: Cognitive complaints are among the most frequent symptoms of post-acute sequelae of COVID-19 (PASC). This study aimed to investigate the frequency, characteristics, and clinical correlates of cognitive complaints (CC) in PASC, particularly ... ...

    Abstract Background: Cognitive complaints are among the most frequent symptoms of post-acute sequelae of COVID-19 (PASC). This study aimed to investigate the frequency, characteristics, and clinical correlates of cognitive complaints (CC) in PASC, particularly in relation to objective neuropsychological (NP) performance.
    Methods: Seventy-four participants underwent psychiatric, medical, and NP testing approximately 7 months after acute COVID-19. The Patient Assessment of Own Functioning Inventory (PAOFI) was used to characterize the frequency and severity of CC in domains of memory, language, and cognitive/executive function. The associations of CC with sociodemographic, medical, psychiatric, and NP variables were assessed utilizing correlational analysis, logistic regression, and pairwise comparisons of those categorized as having CC vs. not having CC.
    Results: Taken together, approximately one-third of the study participants had clinically significant CC. Memory difficulty was the most frequent CC, although all categories were frequently endorsed. Memory and cognitive/executive complaints correlated with NP tests in these and multiple other NP domains. CC were more likely to be under-reported in those with diminished NP performance than over-reported in those without diminished performance. Acute COVID-19 symptom severity, elevated depressive symptoms, and NP tests of diminished attention and psychomotor processing speed were independent predictors of CC in logistic regression.
    Conclusions: Cognitive complaints after acute COVID-19 should be taken seriously, as they are likely to reflect diminished NP performance, as well as medical, psychiatric, and functional burdens. However, patients with PASC may not accurately identify or characterize objective cognitive difficulties, so programs offering comprehensive care for patients with PASC should offer formal neuropsychological testing.
    Language English
    Publishing date 2023-12-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci14010003
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  8. Article: Frequency and Characteristics of Depression and Its Association with Diminished Quality of Life in a Cohort of Individuals with Post-Acute Sequelae of COVID-19.

    Shahar, Sivan / Lynch, Sean / Dornbush, Rhea / Klepacz, Lidia / Smiley, Abbas / Ferrando, Stephen J

    Neuropsychiatric disease and treatment

    2023  Volume 19, Page(s) 2069–2079

    Abstract: Background: Approximately one-third of COVID-19 survivors will experience persistent symptoms, which may include neurological and psychiatric disturbances. Previous research has suggested that up to 45% of people develop clinically significant ... ...

    Abstract Background: Approximately one-third of COVID-19 survivors will experience persistent symptoms, which may include neurological and psychiatric disturbances. Previous research has suggested that up to 45% of people develop clinically significant depressive symptoms post-COVID. This study sought to determine frequency, symptom profile, and clinical correlates of depression post-COVID.
    Methods: Seventy-five participants who had recovered from COVID-19 underwent neurocognitive, psychiatric, medical, and cognitive testing/screening. The primary measures of interest in this report included the Patient Health Questionnaire (PHQ-9), a 9-item depression-screening tool, and the Endicott Quality of Life Enjoyment and Satisfaction Questionnaire.
    Results: One-third of study participants screened as positive on the PHQ-9 for clinically significant depression, with the most commonly reported symptom being fatigue, followed by sleep disturbance and poor concentration. Also reported were decreased satisfaction in employment, sexual life, and mood. Depressed patients described greater illness severity during COVID-19 infection and subjective cognitive impairment, which was not found on neurocognitive testing. The only significant predictor of depression was COVID-19 illness severity.
    Limitations: A significant portion of participants was a clinical population with specific post-COVID complaints and was predominately comprised of white females. Formal psychiatric evaluation was not performed.
    Conclusion: Many individuals may experience depression after COVID-19 infection, with symptoms appearing to be predominately somatic in nature and correspond with COVID-19 illness severity.
    Language English
    Publishing date 2023-10-03
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2186503-6
    ISSN 1178-2021 ; 1176-6328
    ISSN (online) 1178-2021
    ISSN 1176-6328
    DOI 10.2147/NDT.S427957
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6068: Show issues Location:
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  9. Article: Two Women with History of Bipolar Disorder.

    Mahgoub, Nahla / Kotbi, Nabil / Ferrando, Stephen J / Young, Robert C

    Psychiatric annals

    2020  Volume 40, Issue 4, Page(s) 181–183

    Language English
    Publishing date 2020-04-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 222181-0
    ISSN 0048-5713
    ISSN 0048-5713
    DOI 10.3928/00485713-20100330-01
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    Zs.A 1115: Show issues Location:
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  10. Article ; Online: Screening for brain fog: Is the montreal cognitive assessment an effective screening tool for neurocognitive complaints post-COVID-19?

    Lynch, Sean / Ferrando, Stephen J / Dornbush, Rhea / Shahar, Sivan / Smiley, Abbas / Klepacz, Lidia

    General hospital psychiatry

    2022  Volume 78, Page(s) 80–86

    Abstract: Background: Cognitive complaints are one of the most frequent symptoms reported in post-acute sequelae of COVID-19 (PASC). The Montreal Cognitive Assessment (MoCA) has been used to estimate prevalence of cognitive impairment in many studies of PASC, and ...

    Abstract Background: Cognitive complaints are one of the most frequent symptoms reported in post-acute sequelae of COVID-19 (PASC). The Montreal Cognitive Assessment (MoCA) has been used to estimate prevalence of cognitive impairment in many studies of PASC, and is commonly employed as a screening test in this population, however, its validity has not been established.
    Objective: To determine the utility of the MoCA to screen for cognitive impairment in PASC.
    Methods: Sixty participants underwent neuropsychological, psychiatric, and medical assessments, as well as the Montreal Cognitive Assessment, 6-8 months after acute COVID-19 infection.
    Results: The overall sample had a mean score of 26.1 on the MoCA, with approximately one third screening below the cutoff score of 26, similar to the rate of extremely low NP test performance. MoCA score was inversely correlated with fatigue and depression measures and ethnic minority participants scored on average lower, despite similar education and estimated premorbid function. The MoCA had an accuracy of 63.3% at detecting any degree of diminished NP performance, and an accuracy of 73.3% at detecting extremely low NP performance.
    Discussion/conclusion: The MoCA may not be accurate for detecting neither mild nor more severe degrees of diminished NP test performance in PASC. Therefore, patients with persistent cognitive complaints in the setting of PASC who score in the normal range on the MoCA should be referred for formal NP assessment.
    MeSH term(s) Brain ; COVID-19 ; Cognitive Dysfunction/diagnosis ; Cognitive Dysfunction/epidemiology ; Cognitive Dysfunction/etiology ; Ethnicity ; Humans ; Mental Status and Dementia Tests ; Minority Groups ; Neuropsychological Tests
    Language English
    Publishing date 2022-07-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 392299-6
    ISSN 1873-7714 ; 0163-8343
    ISSN (online) 1873-7714
    ISSN 0163-8343
    DOI 10.1016/j.genhosppsych.2022.07.013
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